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Social Science 2024-07-12

Judge: Texas university must release records on research study that resulted in deaths of dozens of animals

SAN ANGELO, Texas —Tom Green County District Court Judge Barbara L. Walther ruled Thursday, July 11, 2024, that Angelo State University must release public records relating to an experiment conducted on dozens of mice that resulted in the animals’ unnecessary suffering and death, reportedly to study the impact of the foster care system on human children. The ruling overturns Texas Attorney General Ken Paxton’s Nov. 17, 2022 decision to side with the university in denying the records. On July 13, 2023, the Physicians Committee for Responsible Medicine, a Washington, D.C. based health advocacy group of more than 17,000 doctor members that encourages higher standards ...
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UMass Amherst food scientist rises to the challenge of giving marbled fatty feel and taste to plant-based meat
Science 2024-07-12

UMass Amherst food scientist rises to the challenge of giving marbled fatty feel and taste to plant-based meat

One of the challenges of creating realistic-looking and delectable plant-based meat is mimicking the marbled effect of animal fat that many carnivores expect and enjoy. A University of Massachusetts Amherst food scientist has a plan to tackle this quandary by developing new technology supported by a $250,000 grant from the Good Food Institute. The not-for-profit think tank promotes plant-based alternatives to meat, dairy and eggs, as well as cultivated “clean meat” grown from animal cells in a facility. The technology proposed ...
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Environment 2024-07-12

Complex impact of large wildfires on ozone layer dynamics unveiled by new study

In a revelation that highlights the fragile balance of our planet's atmosphere, scientists from China, Germany, and the USA have uncovered an unexpected link between massive wildfire events and the chemistry of the ozone layer. Published in Science Advances, this study reveals how wildfires, such as the catastrophic 2019/20 Australian bushfires, impact the stratosphere in previously unseen ways. The ozone layer, a crucial shield protecting life on Earth from harmful ultraviolet (UV) radiation, has been on a path to ...
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Brain inflammation triggers muscle weakness after infections
Medicine 2024-07-12

Brain inflammation triggers muscle weakness after infections

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the brain to the muscles and causes a loss of muscle function. The study, in fruit flies and mice, also identified ways to block this process, which could have ...
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Medicine 2024-07-12

Research alert: All stem cell therapies are not created equal

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current “one-cell-cures-all” paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients. The researchers analyzed cell populations of autologous bone marrow aspirate concentrate (BMAC) and adipose-derived ...
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Environment 2024-07-12

Complex impact of large wildfires on ozone layer dynamics

The ozone layer, a crucial shield protecting life on Earth from harmful ultraviolet (UV) radiation, has been on a path to recovery thanks to the Montreal Protocol. This landmark international treaty, adopted in 1987, successfully led to phasing out the production of numerous substances responsible for ozone depletion. Over the past decades, the ozone layer has shown significant signs of healing, a testament to global cooperation and environmental policy. However, the stability of this vital atmospheric layer is now facing a new and unexpected challenge. During the 2019/20 Australian wildfires, ...
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Technology 2024-07-12

AI found to boost individual creativity – at the expense of less varied content

Stories written with AI assistance have been deemed to be more creative, better written and more enjoyable. A new study published in the journal Science Advances finds that AI enhances creativity by boosting the novelty of story ideas as well as the ‘usefulness’ of stories – their ability to engage the target audience and potential for publication. It finds that AI “professionalizes” stories, making them more enjoyable, more likely to have plot twists, better written and less boring. In ...
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Science 2024-07-12

Texas A&M research collaboration uncovers how domestic rabbits become feral in the wild

Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have uncovered how natural selection “rewilds” domestic rabbits. The study, published in Nature Ecology and Evolution, helps answer the question of how normally tame rabbits — which have many natural predators — can become a force of ecological destruction when purposefully or accidentally reintroduced to the wild. Here Comes Peter Cottontail Every gardener knows how much of a nuisance rabbits can be, but ...
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Technology 2024-07-12

Scientists find new way global air churn makes particles

By Leah Shaffer You can think of our atmosphere as a big chemistry set, a global churn of gaseous molecules and particles that constantly bounce off and change each other in complicated ways. While the particles are very small, often less than 1% of the thickness of human hair, they have outsized impacts. For example, particles are the seeds of cloud droplets, and the abundance of the particles changes the reflectivity and the amount of clouds, rainfall and climate. Now, researchers at Washington University in St. ...
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Science 2024-07-12

Researchers discover a new neural biomarker for OCD

A recent study from Baylor College of Medicine and Texas Children’s Hospital has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS),  a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, led by led by Drs. Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, ...
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Vivid portrait of interacting galaxies marks Webb’s second anniversary
Science 2024-07-12

Vivid portrait of interacting galaxies marks Webb’s second anniversary

Two for two! A duo of interacting galaxies commemorates the second science anniversary of NASA’s James Webb Space Telescope, which takes constant observations, including images and highly detailed data known as spectra. Its operations have led to a “parade” of discoveries by astronomers around the world. “Since President Biden and Vice President Harris unveiled the first image from the James Webb Space Telescope two years ago, Webb has continued to unlock the mysteries of the universe,” said NASA Administrator Bill Nelson. “With remarkable images from the ...
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UMass Amherst awarded $2.1 million to advance the science of engagement in community-academic research partnerships
Social Science 2024-07-12

UMass Amherst awarded $2.1 million to advance the science of engagement in community-academic research partnerships

University of Massachusetts Amherst researcher Thomas Mackie has received a $2.1 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) to advance the meaningful engagement of communities that are affected by mental health disparities and underrepresented in research partnerships. The study, entitled “Improving Research Partnership With Engagement Mapping: A Pilot Study to Advance Engagement Science” and co-led by Karen Tabb, a University of Illinois Urbana-Champaign researcher, is designed to empower community partners to have a greater role ...
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Science 2024-07-12

With gene editing, mice with a form of inherited deafness can hear again

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people. Zheng-Yi Chen, DPhil., and his colleagues at Mass Eye and Ear in Boston and other institutions studied a rare form of genetic deafness called autosomal dominant deafness-50 (DFNA50). ...
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Sant Pau researchers discover a new gene that causes ALS
Science 2024-07-12

Sant Pau researchers discover a new gene that causes ALS

Sant Pau researchers discover a new gene that causes ALS   Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease. Specifically, it is a shared mutation (c.1586C>T; p.Pro529Leu) in the ARPP21 gene that ...
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Synthetic biology reveals the secrets of life without oxygen
Science 2024-07-12

Synthetic biology reveals the secrets of life without oxygen

Long before photosynthesis brought free oxygen into the world, the earth was already populated by numerous organisms. Oxygen was life-threatening for them and therefore they developed completely different metabolic pathways to those we know from plants, animals and humans. Anaerobic bacteria have survived the ages in special, oxygen-free niches, some of them very close to us: as an essential part of the intestinal microbiome, where they are of enormous importance for the well-being of the organism. However, certain anaerobes can ...
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Environment 2024-07-12

UC3M student startup, Solaris Vita, awarded in Europe's largest entrepreneurship competition

Solaris Vita, a startup created by students at Universidad Carlos III de Madrid (UC3M), has won second place in the "Innovation of the Year" category at Gen-E 2024, the largest European youth entrepreneurship competition, organized by Junior Achievement Europe. This is the first time that a Spanish university team has won this award. The promoters of Solaris Vita, Miguel Iglesias (Industrial Engineering graduate from UC3M) and Yann Guichard (Economics student at the University), competed ...
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How plant cold specialists can adapt to the environment
Environment 2024-07-12

How plant cold specialists can adapt to the environment

Plant cold specialists like the spoonworts have adapted well to the cold climates of the Ice Ages. As cold and warm periods alternated, they developed a number of species that also resulted in a proliferation of the genome. Evolutionary biologists from the universities of Heidelberg, Nottingham, and Prague studied the influence this genome duplication has on the adaptive potential of plants. The results show that polyploids – species with more than two sets of chromosomes – can have an accumulation of structural mutations with signals for a possible local ...
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Medicine 2024-07-12

Biomarkers reveal how patients with glaucoma may respond to treatment

Markers in the blood that predict whether glaucoma patients are at higher risk of continued loss of vision following conventional treatment have been identified by researchers at UCL and Moorfields Eye Hospital. Over 700,000 people in the UK have glaucoma and it is the leading cause of irreversible blindness worldwide. The condition occurs when the cells in the eye that help you see (called retinal ganglion cells) start to die. The main risk factors for glaucoma are high eye pressure and older age. Currently, all licenced treatments are designed to lower pressure in the eye – also known as intraocular pressure. However, some patients ...
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Microbeads with adaptable fluorescent colors from visible light to near-infrared
Science 2024-07-12

Microbeads with adaptable fluorescent colors from visible light to near-infrared

1. A research team at NIMS has successfully developed an environmentally friendly, microspherical fluorescent material primarily made from citric acid. These microbeads emit various colors of light depending on the illuminating light and the size of the beads, which suggests a wide range of applications. Furthermore, the use of plant-derived materials allows for low-cost and energy-efficient synthesis. 2. Conventional luminescent devices commonly utilized thin films of compound semiconductors containing metals or sintered inorganic materials with rare earth elements. However, in a circular economy, there ...
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Medicine 2024-07-12

Neighborhood disadvantage and prostate tumor RNA expression of stress-related genes

About The Study: In this cross-sectional study, the expression of several stress-related genes in prostate tumors was higher among men residing in disadvantaged neighborhoods. This study is one of the first to suggest associations of neighborhood disadvantage with prostate tumor RNA expression. Additional research is needed in larger studies to replicate findings and further investigate interrelationships of neighborhood factors, tumor biology, and aggressive prostate cancer to inform interventions to reduce disparities.  Corresponding Author: To contact the corresponding author, ...
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Medicine 2024-07-12

Screen media use and mental health of children and adolescents

About The Study: This secondary analysis of a randomized clinical trial found that a short-term reduction in leisure-time screen media use within families positively affected psychological symptoms of children and adolescents, particularly by mitigating internalizing behavioral issues and enhancing prosocial behavior. More research is needed to confirm whether these effects are sustainable in the long term.  Corresponding Author: To contact the corresponding author, Jesper Schmidt-Persson, Ph.D., email jesp@kp.dk. To ...
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Medicine 2024-07-12

Mediterranean diet and cardiometabolic biomarkers in children and adolescents

About The Study: The findings of this study suggest that Mediterranean diet-based interventions may be useful tools to optimize cardiometabolic health among children and adolescents.  Corresponding Author: To contact the corresponding author, Jose Francisco Lopez-Gil, Ph.D., email josefranciscolopezgil@gmail.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.21976) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...
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A chemical claw machine bends and stretches when exposed to vapors
Science 2024-07-12

A chemical claw machine bends and stretches when exposed to vapors

Scientists at King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have developed a tiny “claw machine” that is able to pick up and drop a marble-sized ball in response to exposure to chemical vapors. The findings, published July 12 in the journal Chem, point to a technique that can enable soft actuators—the parts of a machine that make it move—to perform multiple tasks without the need for additional costly materials. While existing soft actuators can be “one-trick ponies” restricted to one type of movement, this novel composite film contorts itself ...
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Living in disadvantaged neighborhoods influences stress-related genes, which may contribute to aggressive prostate cancer in African American men
Medicine 2024-07-12

Living in disadvantaged neighborhoods influences stress-related genes, which may contribute to aggressive prostate cancer in African American men

BALTIMORE, MD, July 12, 2024 — Those living in disadvantaged neighborhoods have significantly higher activity of stress-related genes, new research suggests, which could contribute to higher rates of aggressive prostate cancer in African American men. The study, which was co-led by the University of Maryland School of Medicine (UMSOM) and Virginia Commonwealth University (VCU), was published today in JAMA Network Open. African American men have a higher incidence of prostate cancer and are more than twice as likely to die from the disease than White men in the U.S. They are often diagnosed with an ...
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Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock
Medicine 2024-07-12

Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock

Overview: DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.   DNA aptamers can specifically bind to biomolecules to modify their function, potentially making them ideal oligonucleotide therapeutics. We screened the DNA aptamer melanopsin (OPN4), a blue light photopigment in the retina that plays a key role in the use of light signals to reset the phase of circadian rhythms in the central clock. First, 15 DNA aptamers of melanopsin (Melapts) were identified following eight rounds of Cell-SELEX ...
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