New research published in Anaesthesia (the journal of the Association of Anaesthetists) shows that for children undergoing emergency surgery for appendicitis in the UK, black children had a four times greater risk of postoperative complications compared with white children. The study was led by Dr Amaki Sogbodjor, from Great Ormond Street Hospital and University College London (UCL), and Professor Ramani Moonesinghe, UCL Division of Surgery and Interventional Science, London, UK and Director, Central London National ...

NASA’s James Webb Space Telescope has found the best evidence yet for emission from a neutron star at the site of a recently observed supernova. The supernova, known as SN 1987A, was a core-collapse supernova, meaning the compacted remains at its core formed either a neutron star or a black hole. Evidence for such a compact object has long been sought, and while indirect evidence for the presence of a neutron star has previously been found, this is the first time that the effects of high-energy ...

Study finds guided parent-child discussions are effective at addressing subtle racism When parents discuss racism with their children, negative biases toward Black people are significantly reduced in both parent and child EVANSTON, Ill. --- Experts have long pointed out the need for white parents to have conversations that directly address racism with their children to reduce racial bias. But many parents fail to have these crucial discussions. Psychology researchers at Northwestern University have published ...

When a recession takes a bite out of an entrepreneur’s personal stock portfolio, does that person’s business suffer more than those of older and larger competitors?  New research by Marius Ring, assistant professor of finance at Texas McCombs, finds a link between the wealth of small-business owners and the health of their companies during economic downturns. When their stock portfolios lose value, their businesses suffer ripple effects: less financing and curtailed hiring.  “Entrepreneurial wealth follows the ups and downs of economic cycles,” Ring says. “I show that for entrepreneurs whose stock portfolios take a hit, their businesses ...

DURHAM, N.C. – Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. The research shows bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes. These duplicated resistance genes are often linked to “jumping genes” called transposons that can move from strain to strain. Not only does this provide a mechanism for resistance to spread, having multiple copies of a resistance ...

BEAUFORT, N.C. – When it comes to protecting a crucial resource in the face of changing conditions, it’s important to know how the humans reliant on that resource have organized themselves. Especially if there isn’t a lot of government supervision. A new study of small-scale fisheries in Mexico’s Gulf of California has found that the fishers’ response to a changing climate can be strongly influenced by what they fish for and how they’re organized. The work appears in the January 2024 issue of Global Environmental Change. “When we ...

CORVALLIS, Ore. – Forests in the coolest, wettest parts of the western Pacific Northwest are likely to see the biggest increases in burn probability, fire size and number of blazes as the climate continues to get warmer and drier, according to new modeling led by an Oregon State University scientist. Understanding how fire regimes may change under future climate scenarios is critical for developing adaptation strategies, said the study’s lead author, Alex Dye. Findings were published today in JGR Biogeosciences. Dye, ...

While the microchips inside electronic devices like cell phones and computers are incredibly small, transistors — the tiny electrical switches inside of microchips — are approaching the atomic level. Today’s microchips pack over 100 million transistors in an area the size of a pin head. Despite their almost unimaginable size, the total number of such microelectronic devices consume an enormous amount of energy, which is growing exponentially. Predictions indicate that 20% of the world’s energy could be consumed ...

A Weill Cornell Medicine-led research team has been awarded a 2024 Top 10 Clinical Research Achievement Award from the Clinical Research Forum in recognition of an influential 2023 New England Journal of Medicine study on early-stage lung cancer resection. The award is one of 10 given annually by the Clinical Research Forum for highly innovative and clinically translatable research with the potential to provide major benefits to patients. The Washington, D.C.-based organization is an influential advocate for government funding of clinical research and the interests of American clinical research institutions generally. The winners will present their award-winning ...

When certain connections in the brain do not function correctly, disorders such as Parkinson’s disease, dystonia, obsessive-compulsive disorder (OCD), and Tourette’s syndrome may result. Targeted stimulation of specific areas in the brain can help alleviate symptoms. To pinpoint the exact therapeutic target areas of the brain, a team led by researchers from Charité – Universitätsmedizin and Brigham and Women’s Hospital analyzed data from patients across the globe who had undergone implantation of tiny electrodes to stimulate ...

Join Gunther Eysenbach, the founder, CEO, and executive editor of JMIR Publications, in this new video as he reflects on the company's 25th anniversary and its remarkable journey in the scholarly publishing industry. Eysenbach discusses the inception of the Journal of Medical Internet Research and the driving forces behind creating an open access eHealth journal. He emphasizes the significance of innovation both in content and form, highlighting the company's early adoption of internet-based technologies ...

URBANA, Ill. – Black Americans experience racial discrimination as a chronic stressor that influences their quality of life. But it exists in conjunction with other social factors that may modify the impact in various ways. A new study from the University of Illinois Urbana-Champaign explores how discrimination, gender, and social class affect individual well-being and relationship quality for Black Americans. “It’s well documented that discrimination negatively impacts individual quality of life, but research on how it affects relationships is mixed. Some studies find it has a negative effect, others that it has no effect, and some even find a positive effect, ...

Compound vital for all life likely played a role in life’s origin A chemical compound essential to all living things has been synthesised in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life, finds a new study led by UCL researchers. The compound, pantetheine, is the active fragment of Coenzyme A. It is important for metabolism - the chemical processes that maintain life. Earlier studies failed to synthesise pantetheine effectively, leading to suggestions that it was absent at life’s origin. In the new ...

New York, NY (February 22, 2024)—Recent developments in cancer research have highlighted the vital role of the immune system, particularly in the notable successes of cancer immunotherapy. Now, a paradigm-shifting study led by researchers at the Icahn School of Medicine at Mount Sinai in New York in collaboration with the University of Helsinki and Massachusetts General Hospital sheds light on how variations in immune genetics influence lung cancer risk, potentially paving the way for enhanced prevention strategies and screening. The findings were described in the February 22 online issue of Science [DOI number: 10.1126/science.adi3808]. The investigators ...

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in the peer-reviewed journal Science, could lead to the development of noninvasive tests to detect kidney scarring and, eventually, new therapies to reverse the condition. “The key to this discovery was our ability to directly compare injured kidney cells that successfully regenerated with those that did not,” said Sanjeev Kumar, MD, PhD, a nephrologist-scientist in the Board of Governors Regenerative Medicine Institute and the Department of Medicine at Cedars-Sinai and senior author ...

Data from a series of randomized trials in the United States suggests that if teachers move genetics instruction toward more complex genomics concepts, they can help students have a more scientifically accurate understanding of race. This can protect students from believing in unscientific notions of genetic essentialism, including the idea that inequality is genetic. People who believe in genetic essentialism believe – among other ideas – that most racial differences are determined by genes. Essentialist ...

Astronomers using the James Webb Space Telescope (JWST) have found conclusive evidence of a neutron star in the remnant of Supernova 1987A, the only supernova visible to the naked eye in the last 400 years and the most studied supernova in history. Although Supernova 1987A has been observed for more than three decades, scientists have not seen the compact object expected to have been produced during the explosion. Some indirect evidence had suggested that the supernova produced a neutron star, but a black hole wasn’t ruled ...

Roughly a third of the climate cooling that forests achieve by removing carbon dioxide (CO2) from the atmosphere is offset through changes to atmospheric composition and decreased surface reflectivity, researchers report. The findings suggest that the benefits of wide-scale forestation efforts may be overestimated and do not represent a single solution for addressing climate change. They also highlight the urgency of simultaneously focusing on emissions reductions. Planting trees has been widely promoted as a nature-based solution to remove anthropogenic CO2 from the atmosphere to help mitigate ...

More than 100 million years ago, the ancestors of the first snakes were small lizards that lived alongside other small, nondescript lizards in the shadow of the dinosaurs.   Then, in a burst of innovation in form and function, the ancestors of snakes evolved legless bodies that could slither across the ground, highly sophisticated chemical detection systems to find and track prey, and flexible skulls that enabled them to swallow large animals.   Those changes set the stage for the spectacular diversification of snakes over the past 66 million years, allowing them to quickly exploit new opportunities ...

  The side effects of large-scale forestation initiatives could reduce the CO2 removal benefits by up to a third Researchers at the University of Sheffield used computer models, which simulate the land, ocean and atmosphere, to investigate the impact of forestation under future climate scenarios While forestation increases atmospheric CO2 removal, it also changes atmospheric composition and darkens the land surface, reducing its potential to tackle climate change Combining forestation with other climate mitigation ...

New Haven, Conn. — Nearly 30 years ago, scientists discovered a unique class of anticancer molecules in a family of bryozoans, a phylum of marine invertebrates found in tropical waters. The chemical structures of these molecules, which consist of a dense, highly complex knot of oxidized rings and nitrogen atoms, has attracted the interest of organic chemists worldwide, who aimed to recreate these structures from scratch in the laboratory. However, despite considerable effort, it has remained an elusive task. Until now, that is. A team of Yale chemists, writing in the journal Science, ...

A new study, published in Science and co-authored by Dr Patrick Kavanagh of Maynooth University’s Department of Experimental Physics in Ireland, has provided the first conclusive evidence for the presence of the elusive neutron star produced in the supernova SN 1987A. Supernovae are the spectacular end result of the collapse of stars more massive than eight to ten times the mass of the sun. Besides being the main sources of chemical elements such as the carbon, oxygen, silicon, and iron that make life possible, they are also responsible for creating the ...

Scientists can finally show that a neutron star formed from our most well-studied supernova, SN 1987A. The breakthrough was made possible thanks to the James Webb telescope. Supernovae are the spectacular end result of the collapse of stars more massive than 8-10 times the mass of the sun. Besides being the main sources of chemical elements such as carbon, oxygen, silicon, and iron that make life possible, they are also responsible for creating the most exotic objects in the universe, neutron stars and black holes. In 1987, supernova 1987A (SN 1987A) ...

Understanding complex biological and biomedical systems is greatly aided by 3D imaging, which provides much more detailed information than traditional two-dimensional methods. However, live cell and tissue imaging remain challenging due to factors like limited imaging speed and significant scattering in turbid environments. In this context, multimodal microscopy techniques are notable. Specifically, nonlinear techniques like CRS (coherent Raman scattering) use optical vibrational spectroscopy, providing precise chemical imaging in tissues and cells in a label-free way. Furthermore, stimulated Raman scattering (SRS) ...

CAMBRIDGE, MA — Experimental computer memories and processors built from magnetic materials use far less energy than traditional silicon-based devices. Two-dimensional magnetic materials, composed of layers that are only a few atoms thick, have incredible properties that could allow magnetic-based devices to achieve unprecedented speed, efficiency, and scalability. While many hurdles must be overcome until these so-called van der Waals magnetic materials can be integrated into functioning computers, MIT researchers took an important step in this direction by demonstrating precise control of a van der ...