Llama 'nanobodies' could hold key to preventing deadly post-transplant infection
2021-07-22
Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and destroy this potentially deadly virus.
Around four out of five people in the UK are thought to be infected with HCMV, and in developing countries this can be as high as 95%. For the majority of people, the virus remains dormant, hidden away inside white blood cells, where it can remain undisturbed and undetected for decades. ...
Defect engineering assisting in high-level anion doping towards fast charge transfer kinetic
2021-07-22
The research team of Prof. Xiaobo Ji and associate Prof. Guoqiang Zou has proposed an ingenious oxygen vacancy (OV)-engineering strategy to realize high content anionic doping in TiO2 and offered valuable insights into devise electrode materials with fast charge transfer kinetics in the bulk phase. The article titled "High content anion (S/Se/P) doping assisted by defect engineering with fast charge transfer kinetics for high-performance sodium ion capacitors" is published in Science Bulletin. Xinglan Deng is listed as first author and Prof. Guoqiang Zou as corresponding author.
The ...
Scientists come up with new method for simultaneous processing of different types of waste
2021-07-22
An international research team has come up with an innovative method for metal recovery from industrial waste. The new method allows the simultaneous recovery of multiple metals from waste oxides in a single process. This novel route will lower the burden on waste storage facilities with significant contributions to the economic and environmental sustainability of industrial waste management. The study was published in Journal of Environmental Management. This work is the first in a series of studies aimed at developing cost-effective and environmentally sustainable solutions for industrial waste recycling.
Some of the major industries ...
Astronomers make first clear detection of a moon-forming disc around an exoplanet
2021-07-22
Using the Atacama Large Millimetre/submillimeter Array (ALMA), in which the European Southern Observatory (ESO) is a partner, astronomers have unambiguously detected the presence of a disc around a planet outside our Solar System for the first time. The observations will shed new light on how moons and planets form in young stellar systems.
"Our work presents a clear detection of a disc in which satellites could be forming," says Myriam Benisty, a researcher at the University of Grenoble, France, and at the University of Chile, who led the new research published today in The Astrophysical Journal Letters. "Our ALMA observations were obtained at such exquisite resolution that we could clearly identify ...
Spotted: An exoplanet with the potential to form moons
2021-07-22
Cambridge, MA ¬- Astronomers at the Center for Astrophysics | Harvard & Smithsonian have helped detect the clear presence of a moon-forming region around an exoplanet -- a planet outside of our Solar System. The new observations, published Thursday in The Astrophysical Journal Letters, may shed light on how moons and planets form in young stellar systems.
The detected region is known as a circumplanetary disk, a ring-shaped area surrounding a planet where moons and other satellites may form. The observed disk surrounds exoplanet PDS 70c, one of two giant, Jupiter-like planets orbiting a star nearly 400 light-years away. Astronomers had found hints of a "moon-forming" disk around this exoplanet before but since ...
Professional rugby may be associated with changes in brain structure
2021-07-22
Participation in elite adult rugby may be associated with changes in brain structure.
This is the finding of a study of 44 elite rugby players, almost half of whom had recently sustained a mild head injury while playing.
The study, part of the Drake Rugby Biomarker Study, was led by Imperial College London and published in the journal Brain Communications.
The research found a significant proportion of the rugby players had signs of abnormalities to the white matter, in addition to abnormal changes in white matter volume over time.
White matter is the 'wiring' of the brain, and helps brain cells communicate with each other. The research team say more work is now needed to investigate the long-term effects of professional rugby on brain health.
Professor David Sharp, senior author ...
COVID-19: Patients with malnutrition may be more likely to have severe outcomes
2021-07-22
Adults and children with COVID-19 who have a history of malnutrition may have an increased likelihood of death and the need for mechanical ventilation, according to a study published in Scientific Reports.
Malnutrition hampers the proper functioning of the immune system and is known to increase the risk of severe infections for other viruses, but the potential long-term effects of malnutrition on COVID-19 outcomes are less clear.
Louis Ehwerhemuepha and colleagues investigated associations between malnutrition diagnoses and subsequent COVID-19 severity, using medical records for 8,604 children and 94,495 adults (older than 18 years) who were hospitalised with COVID-19 in the United States between March and June 2020. Patients with a diagnosis ...
Study shows cancer misinformation common on social media sites
2021-07-22
A new study published online today in the Journal of the National Cancer Institute reports that one third of the most popular cancer treatment articles on social media contain misinformation. Further, the vast majority of that misinformation has the potential to harm cancer patients by supporting approaches that could negatively impact the quality of their treatment and chances for survival. The study also showed that articles containing misinformation garner more attention and engagement than articles with evidence-based information.
The internet is a major source for health information, and misinformation is growing among many types of health conditions. This is an urgent challenge because it can result in patients making ...
Higher levels of omega-3 acids in the blood increases life expectancy by almost five years
2021-07-22
Levels of omega-3 fatty acids in the blood are as good a predictor of mortality from any cause as smoking, according to a study involving the Hospital del Mar Medical Research Institute (IMIM), in collaboration with The Fatty Acid Research Institute in the United States and several universities in the United States and Canada. The study, published in The American Journal of Clinical Nutrition, used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971.
Researchers have found that omega-3 levels in blood erythrocytes (the so-called red blood cells) are very good mortality risk predictors. The study concludes that "Having higher levels of these ...
Antibiotics may help to treat melanoma
2021-07-22
Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental Medicine.
Researchers from KU Leuven may have found a new weapon in the fight against melanoma: antibiotics that target the 'power plants' of cancer cells. These antibiotics exploit a vulnerability that arises in tumour cells when they try to survive cancer therapy.
"As the cancer evolves, some melanoma cells may escape the treatment and stop proliferating to 'hide' from ...
Mobility restrictions can have unexpected impacts on air quality
2021-07-22
An international collaborative study led by University of Helsinki has conducted a holistic study to investigate the effects of COVID-19 restrictions on several air quality pollutants for the Po Valley region in northern Italy. The area is well known to have one of the worst air quality standards in Europe and is highly influenced by anthropogenic (human-led) activities. The study was done between research groups in Finland, Italy and Switzerland and the results were published in the journal Environmental Science: Atmospheres.
Scientists have combined air quality measurements and computer simulation data over several locations in the region. The resulting studies show that reduced emissions from traffic lead to a strong reduction of nitrogen ...
Targeted removals and enhanced monitoring can help manage lionfish in the Mediterranean
2021-07-22
Targeted removals can be effective in suppressing the number of invasive lionfish found within protected coastlines around the Mediterranean Sea.
However, if they are to really be successful they need to be combined with better long-term monitoring by communities and conservationists to ensure their timing and location achieve the best results.
Those are the key findings of a new study, one of the first of its kind to examine the effectiveness of targeted lionfish removals from both an ecological and a socio-economic perspective.
Scientists working as part of the European Union-funded RELIONMED project ...
Pandemic changed perceptions of masked faces
2021-07-22
The Covid-19 pandemic has improved perceptions of facial attractiveness and healthiness of people wearing face masks in Japan.
Wearing sanitary facemasks was not uncommon in Japan prior to the Covid-19 pandemic. Public health initiatives during the pandemic have led to a drastic increase in the use of facemasks as they reduce the transmission of the SARS-CoV-2 virus. The sanitary-mask effect is a model that predicted how facemasks affected perceptions of facial attractiveness. However, as mindsets might have changed due to the pandemic, it is likely that the sanitary-mask effect has been altered.
A team of four scientists, including Professor Jun I. Kawahara from Hokkaido University's ...
Smokeless tobacco used more by pregnant women in South East Asia than non-pregnant women
2021-07-22
Pregnant women in South East Asia are more likely to use smokeless tobacco than non-pregnant women, despite the added risk of foetal harm during pregnancy.
The study - from the University of York - also suggests that there is no difference in smoking between pregnant women and non-pregnant women in many lower to middle income countries.(LMICs)
Researchers analysed data from 42 lower to middle income countries (LMICs) and also conducted a separate sub-group analysis for the South East Asia Region. (SEAR)
Researchers said the study is the first to report comparative estimates of tobacco use among pregnant and non-pregnant women from the 42 LMICs encompassing 80,454 pregnant and 1,230,262 non-pregnant women.
Dr Radha ...
Survey finds bullying and harassment systemic in astronomy and geophysics
2021-07-22
Results from a new survey of astronomers and geophysicists show that these sciences have a systemic bullying problem; one that is disproportionately worse for women and those from minority groups. In a survey carried out by the Royal Astronomical Society (RAS) last year of over 650 people in the field, 44% of respondents had suffered bullying and harassment in the workplace within the preceding 12 months. Aine O'Brien, RAS Diversity Officer, will present the key results in a talk at the virtual National Astronomy Meeting on Thursday 22 July.
Key initial findings show:
Disabled, and Black and minority ethnic astronomers and geophysicists are 40% more likely to be bullied than their non-disabled and White colleagues respectively.
Women and non-binary people in the field are 50% more ...
Remote 24-hour monitoring shows sizable, positive effect on cancer patients
2021-07-22
Remote 24-hour monitoring for cancer patients receiving chemotherapy helps to better manage side effects and improve quality of life, finds a study published by The BMJ today.
The researchers say remote monitoring can provide a safe, secure, and "real time" system that optimises symptom management and supports patients to remain at home - and is particularly relevant in the context of the covid-19 pandemic.
Effective symptom monitoring and management is essential during chemotherapy for cancer, but current approaches rely on patients recognising that symptoms are severe ...
Government has failed to deliver on smoke free pledge for England
2021-07-22
Two years on from its pledge to make England smoke free by 2030, the UK government has failed to deliver on the policies it promised to deliver this ambition, say a group of leading doctors, professional bodies and charities in The BMJ today.
In an open letter to the Prime Minister and Secretary of State for health, they say smoking is likely to have killed more people last year than covid-19 and it will carry on doing so for many years to come unless the government takes action.
They call for a US-style 'polluter pays' levy on tobacco manufacturers to fund the strategy, saying "the time has come to make the tobacco manufacturers pay to end the epidemic they and they alone have caused."
The rate of decline in smoking in the years leading up to 2019 was not sufficient to deliver ...
Unravelling the knotty problem of the Sun's activity
2021-07-22
A new approach to analysing the development of magnetic tangles on the Sun has led to a breakthrough in a longstanding debate about how solar energy is injected into the solar atmosphere before being released into space, causing space weather events. The first direct evidence that field lines become knotted before they emerge at the visible surface of the Sun has implications for our ability to predict the behaviour of active regions and the nature of the solar interior. Dr Christopher Prior of the Department of Mathematical Sciences, Durham University, will present the work today at the ...
Large-scale study finds greater sedentary hours increases risk of obstructive sleep apnea
2021-07-22
A new study by investigators from Brigham and Women's Hospital examined the relationship between active lifestyles and the risk of obstructive sleep apnea (OSA). The study followed around 130,000 men and women in the United States over a follow-up period of 10-to-18 years and found that higher levels of physical activity and lower levels of sedentary behavior were associated with a lower risk of OSA. Their results are published in the European Respiratory Journal.
"In our study, higher levels of physical activity and fewer hours of TV watching, and sitting either at work or away from home ...
The Lancet: Experts call for urgent action to improve physical activity worldwide
2021-07-22
Not enough progress has been made to address physical inactivity worldwide, with adolescents and people living with disabilities (PLWD) among the least likely populations to have the support needed to meet the World Health Organization (WHO)'s physical activity guidelines. Global efforts to improve physical activity have stalled, with overall deaths caused by physical activity remaining at more than 5 million people per year. [1]
Physical inactivity is linked to an increased risk of non-communicable diseases (NCDs) such as heart disease, diabetes, and some cancers and costs at least $54 billion per year in direct health care costs of which $31 billion is paid by the public sector. The slow progress to improve physical activity worldwide ...
David Williams named 2021 recipient of the IADR Gold Medal Award
2021-07-22
Alexandria, Va., USA - The International Association for Dental Research (IADR) announced David Williams, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK, as the 2021 recipient of the IADR Gold Medal Award. Williams was recognized during the Opening Ceremonies of the virtual 99th General Session & Exhibition of the IADR, held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
Williams is a Professor of Global Oral Health at Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK. He is currently Co-Chair ...
Evidence of sustained benefits of pimavanserin for dementia-related psychosis
2021-07-22
Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published.
Up to half of the 45 million people worldwide who are living with Alzheimer's disease will experience psychotic episodes, a figure that is even higher in some other forms of dementia. Psychosis is linked to a faster deterioration in dementia.
Despite this, there is no approved safe and effective treatment for these particularly distressing symptoms. In people with dementia, widely-used antipsychotics lead to sedation, falls and increased risk of deaths.
Pimavanserin works by blocking serotonin 5HT2A ...
Inheriting mother's friends key to hyena success
2021-07-22
EAST LANSING, Mich. - In the wild, inheriting advantageous physical traits may be the difference between a long life and a short one. But for the spotted hyena, another kind of inheritance, one that has nothing to do with genetics, turns out to be extremely important for health and longevity -- social networks inherited from their mothers.
A new study, based on 27 years of observational data from Michigan State University Distinguished Professor Kay Holekamp, expands a previously established theoretical model of spotted hyena social networking to show how these networks emerge, how long they last and how they affect a hyena's life trajectory.
The paper is featured as the front cover for the journal Science.
"There ...
Long COVID and severe COVID-19 infections associated with Epstein-Barr virus reactivation
2021-07-22
Two recently published studies available on the National Institutes of Health (NIH) website indicate Epstein-Barr virus (EBV) reactivation may play a role both in the development of long COVID symptoms, as well as severe COVID-19 cases.
The first evidence linking EBV reactivation to long COVID symptoms was discovered by Gold et al. (2021) and published in Pathogens. This study can be viewed on the NIH website here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233978/
"We ran Epstein-Barr virus serological tests on COVID-19 patients at least 90 days after testing positive for SARS-CoV-2 infection, comparing EBV ...
Self-collected saliva and courier service -- A feasible diagnostic strategy for COVID-19
2021-07-21
Alexandria, Va., USA - Walter Siqueira, University of Saskatchewan, Saskatoon, Canada, presented the poster "Self-collected Saliva and Courier Service - A Feasible Diagnostic Strategy for COVID-19" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.
Saliva has been proposed as a convenient and cost-effective biofluid for diagnostic purposes and in vitro studies have shown that the addition of stabilizers to saliva preserves it for up to 7-10 days at room temperature, but its translational application ...
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