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Medicine 2024-02-13

Quality of care for patients who call 911 varies greatly across the United States, study finds

Emergency medical service (EMS) systems are not consistently providing optimal care based on new national standards of quality to patients who call 911, according to a new study from the Icahn School of Medicine of Mount Sinai. The study demonstrates that EMS performance on key clinical and patient safety measures varies widely across urban and rural communities. The findings, published in the peer-reviewed Prehospital Emergency Care, identify opportunities that could lead to improved care during 911 responses and improved outcomes for patients across the United States. “EMS systems in the United States have traditionally relied ...
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CRISPR-copies: New tool accelerates and optimizes genome editing
Medicine 2024-02-13

CRISPR-copies: New tool accelerates and optimizes genome editing

CRISPR/Cas systems have undergone tremendous advancement in the past decade. These precise genome editing tools have applications ranging from transgenic crop development to gene therapy and beyond. And with their recent development of CRISPR-COPIES, researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) are further improving CRISPR’s versatility and ease of use. “CRISPR-COPIES is a tool that can quickly identify appropriate chromosomal integration sites for genetic engineering in any organism,” said Huimin Zhao, CABBI Conversion Theme Leader ...
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Medicine 2024-02-13

Teenagers need better reproductive health education to tackle parenthood fears

Nearly half of teenagers are worried about having children and many lack knowledge about their reproductive health, find two new studies by UCL researchers. The studies, published in Human Fertility and Health Education Journal, used survey results from 931 students in England aged 16 to 18, collected between May 2021 and July 2022. The Human Fertility paper found that a majority of students (64%) still wanted to have children in the future – with nearly half (49%) desiring to have two children. However, 45% of all participants said that they had concerns about future ...
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Medicine 2024-02-13

Data-driven app results in 25% fewer emergency hospital admissions from care homes

The use of a digital remote monitoring technology in care homes has been found to reduce hospital A&E attendances by 11% and emergency admissions by 25% in a new study from the Health Data Research UK (HDR UK) Better Care programme, published today in Age and Ageing - the official journal of the British Geriatrics Society. There are over 400,000 people living in care homes across the UK, many of whom will be living with complex medical needs that put them at greater risk of needing emergency healthcare, especially during the winter months. Through the HDR UK Better Care programme, a collaboration between the universities ...
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In rural states, gardening and foraging helped prevent hunger during COVID: Study
Medicine 2024-02-13

In rural states, gardening and foraging helped prevent hunger during COVID: Study

New research on rural New Englanders shows that gardening, hunting, fishing and other HWFP activities are important tools for maintaining food security through extreme events, such as pandemics or climate change events.  University of Vermont and University of Maine researchers found that both food insecurity and home and wild food production (HWFP) – gardening, hunting, fishing, foraging, and having “backyard” poultry or livestock – increased significantly during the COVID-19 pandemic, and those who undertook HWFP activities exhibited improved food security 9-12 months later.   The paper, published in Scientific Reports, surveyed ...
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Medicine 2024-02-13

New study finds roughly 1 in 10 pregnant people will develop long COVID

UNDER EMBARGO UNTIL:  Feb. 12, 2024 5:45 p.m. Eastern Standard Time                                                                                          Media Contacts: Karen Addis, APR, karen@addispr.com, +1 (301) 787-2394; Kerri Wade, MPA, kwade@smfm.org, +1 ...
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Differential expression of Mad2 gene in human esophageal cancer
Medicine 2024-02-12

Differential expression of Mad2 gene in human esophageal cancer

“[...] people of the northeastern region [of India] consume betel quid, consisting of raw areca nut [...]. People often swallow the entire betel-quid after chewing, which is believed to contribute to the development of oral, esophageal, and gastric cancers.” BUFFALO, NY- February 12, 2024 – A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal ...
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Space 2024-02-12

RIT's Center for Detectors to work on two NASA projects

Rochester Institute of Technology’s Center for Detectors has been chosen by NASA for two research programs: Early Stage Innovations (ESI) and Strategic Astrophysics Technology (SAT), with the hope of helping future spacecraft find new discoveries in the vast universe. Under the leadership of Center for Detectors Director Don Figer, the team will be advancing and characterizing single-photon sensing complementary metal-oxide semiconductor (CMOS) image sensors to determine if they can survive the harsh radiation environments in NASA missions. The intent is to fly these types of detectors on future missions to find life on Jupiter’s ...
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Archaeologists discover oldest known bead in the Americas
Science 2024-02-12

Archaeologists discover oldest known bead in the Americas

University of Wyoming archaeology Professor Todd Surovell and his team of collaborators have discovered a tube-shaped bead made of bone that is about 12,940 years old. The bead, found at the La Prele Mammoth site in Converse County, is the oldest known bead in the Americas. Surovell’s research was published in the peer-reviewed journal Scientific Reports; the paper is titled “Use of hare bone for the manufacture of a Clovis bead.” Members of the research team included people from UW, the Office of the Wyoming State Archaeologist, the University of Manchester, Weber ...
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Interferon-gamma drives brain pathology in a mouse model of multiple system atrophy
Medicine 2024-02-12

Interferon-gamma drives brain pathology in a mouse model of multiple system atrophy

BIRMINGHAM, Ala. – Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting pathogenesis features neuroinflammation, demyelination and neurodegeneration. Oligodendrocytes produce myelin, an insulating sheath on the axons of nerves. In 2020, Ashley Harms, Ph.D., and University of Alabama at Birmingham colleagues published an Acta Neuropathologica study that used a mouse model to show that the ...
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Medicine 2024-02-12

Drought may drive deadly amphibian disease, researchers find

UNIVERSITY PARK, Pa. — Pumpkin toadlets are in trouble. Progressively severe droughts are disrupting the microbiomes of the thumbnail-sized orange frogs, potentially leaving them vulnerable to a deadly fungal disease, according to a new study by an international research team. The finding suggests that abnormal rainfall patterns, which are expected to worsen due to climate change and deforestation, may upset mutually beneficial relationships between wildlife and microorganisms, leading to biodiversity decline.   The researchers, led by Penn State doctoral ...
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Medicine 2024-02-12

New study finds commonly used antibiotic is a cost-saving treatment for reducing maternal sepsis, death or infection in developing countries

UNDER EMBARGO UNTIL: Feb. 12, 2024, 4:30 PM EST                                                                                Media Contacts:  Karen Addis, APR, karen@addispr.com, +1 (301) 787-2394; Kerri Wade, MPA, kwade@smfm.org, +1 (202) 236-1780                                National ...
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Reshaping our understanding of granular systems
Science 2024-02-12

Reshaping our understanding of granular systems

Your morning cereal, a jar of nuts, the sands of distant planets, and even the concrete in your city are all examples of granular systems surrounding us. And such systems are harboring secrets that could change the way we mix things up. In a new paper published in the journal Proceedings of the National Academy of Sciences (PNAS), scientists at the University of Rochester, including Rachel Glade, an assistant professor of earth and environmental sciences and of mechanical engineering; Fernando David Cúñez, a former postdoctoral research associate ...
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Medicine 2024-02-12

Can hydrogels help mend a broken heart?

You can mend a broken heart this valentine’s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.   University of Waterloo chemical engineering researcher Dr. Elisabeth Prince teamed up with researchers from the University of Toronto and Duke University to design the synthetic material made using cellulose nanocrystals, which are derived from wood pulp. The material is engineered to replicate the fibrous nanostructures and properties of human tissues, thereby recreating its unique biomechanical properties. "Cancer is a diverse disease and two patients with the same type of cancer will often respond ...
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Medicine 2024-02-12

New study finds that pregnancy complications can also affect child’s health later in life

Hypertensive disorders of pregnancy (HDP) and gestational diabetes (GDM) are two of the most common pregnancy complications and put pregnant people at increased risk of developing cardiovascular disease later in life. Now, in a new study to be presented today at the Society for Maternal-Fetal Medicine’s (SMFM) annual meeting, The Pregnancy Meeting™, researchers will unveil findings that suggest these pregnancy complications may also result in worse cardiovascular health for the child.  In a secondary analysis of 3,317 maternal-child pairings from the prospective Hyperglycemia ...
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Scientists discover biological mechanism of hearing loss caused by loud noise – and find a way to prevent it
Science 2024-02-12

Scientists discover biological mechanism of hearing loss caused by loud noise – and find a way to prevent it

Anyone who has ever been to a loud concert knows the feeling of ringing ears. Some people experience temporary or even permanent hearing loss or drastic changes in their perception of sound after the loud noises stop. Thanos Tzounopoulos, Ph.D., director of the Pittsburgh Hearing Research Center at the University of Pittsburgh School of Medicine has focused his scientific career on investigating how hearing works and developing ways to treat tinnitus and hearing loss. In a paper published today in ...
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Technology 2024-02-12

Widespread machine learning methods behind ‘link prediction’ are performing very poorly

As you scroll through any social media feed, you are likely to be prompted to follow or friend another person, expanding your personal network and contributing to the growth of the app itself. The person suggested to you is a result of link prediction: a widespread machine learning (ML) task that evaluates the links in a network — your friends and everyone else’s — and tries to predict what the next links will be. Beyond being the engine that drives social media expansion, link prediction is also used in a wide range of scientific research, such as predicting the interaction between genes and proteins, and is used by researchers as a benchmark for ...
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The hidden rule for flight feathers—and how it could reveal which dinosaurs could fly
Earth Science 2024-02-12

The hidden rule for flight feathers—and how it could reveal which dinosaurs could fly

Birds can fly— at least, most of them can. Flightless birds like penguins and ostriches have evolved lifestyles that don’t require flight. However, there’s a lot that scientists don’t know about how the wings and feathers of flightless birds differ from their airborne cousins. In a new study in the journal PNAS, scientists examined hundreds of birds in museum collections and discovered a suite of feather characteristics that all flying birds have in common. These “rules” provide clues as to how the dinosaur ancestors of modern birds first evolved the ability to fly, ...
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Machine learning promises to accelerate metabolism research
Technology 2024-02-12

Machine learning promises to accelerate metabolism research

A new study shows that it is possible to use machine learning and statistics to address a problem that has long hindered the field of metabolomics: large variations in the data collected at different sites. “We don’t always know the source of the variation,” said Daniel Raftery, professor of anesthesiology and pain medicine at the University of Washington School of Medicine in Seattle. “It could be because the subjects are different with different genetics, diets and environmental exposures. Or it could be the way samples were collected and ...
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Researchers uncover a key link in legume plant-bacteria symbiosis
Medicine 2024-02-12

Researchers uncover a key link in legume plant-bacteria symbiosis

Legume plants have the unique ability to interact with nitrogen-fixing bacteria in the soil, known as rhizobia. Legumes and rhizobia engage in symbiotic relations upon nitrogen starvation, allowing the plant to thrive without the need for externally supplied nitrogen. Symbiotic nodules are formed on the root of the plant, which are readily colonized by nitrogen-fixing bacteria. The cell-surface receptor SYMRK (symbiosis receptor-like kinase) is responsible for mediating the symbiotic signal from rhizobia perception to formation of the nodule. ...
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Genetic analysis and archaeological insight combine to reveal the ancient origins of the fallow deer
Science 2024-02-12

Genetic analysis and archaeological insight combine to reveal the ancient origins of the fallow deer

Modern populations of fallow deer possess hidden cultural histories dating back to the Roman Empire which ought to be factored into decisions around their management and conservation. New research, bringing together DNA analysis with archaeological insights, has revealed how fallow deer have been repeatedly moved to new territories by humans, often as a symbol of colonial power or because of ancient cultures and religions. The results show that the animal was first introduced into Britain by the Romans ...
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Researchers studying ocean transform faults, describe a previously unknown part of the geological carbon cycle
Environment 2024-02-12

Researchers studying ocean transform faults, describe a previously unknown part of the geological carbon cycle

Woods Hole, Mass. (February 12, 2024) – Studying a rock is like reading a book. The rock has a story to tell, says Frieder Klein, an associate scientist in the Marine Chemistry & Geochemistry Department at the Woods Hole Oceanographic Institution (WHOI).    The rocks that Klein and his colleagues analyzed from the submerged flanks of the St. Peter and St. Paul Archipelago in the St. Paul’s oceanic transform fault, about 500 km off the coast of Brazil, tells a fascinating and previously unknown story about parts of the geological ...
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Medicine 2024-02-12

Salt substitutes help to maintain healthy blood pressure in older adults

The replacement of regular salt with a salt substitute can reduce incidences of hypertension, or high blood pressure, in older adults without increasing their risk of low blood pressure episodes, according to a recent study in the Journal of the American College of Cardiology. People who used a salt substitute had a 40% lower incidence and likelihood of experiencing hypertension compared to those who used regular salt. According to the World Health Organization, hypertension is the leading risk factor for cardiovascular disease and mortality. It affects over 1.4 billion adults and results in 10.8 million deaths per year worldwide. One of the ...
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Medicine 2024-02-12

Heart disease risk factors in women highlight need for increased awareness, prevention

Statement Highlights: The new scientific statement highlights heart disease as the leading cause of death for women and emerging evidence that has identified several gender-specific risk factors for heart disease in women, including complications during pregnancy and premature menopause. Compared to men, women also have different symptoms of heart disease, are less likely to receive evidence-based therapies and are more likely to have adverse cardiovascular outcomes after a cardiac event. Targeted public health interventions ...
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SETI institute employs SETI ellipsoid technique for searching for signals from distant civilizations
Engineering 2024-02-12

SETI institute employs SETI ellipsoid technique for searching for signals from distant civilizations

February 12, 2024, Mountain View, CA -- In a paper published in the Astronomical Journal, a team of researchers from the SETI Institute, Berkeley SETI Research Center and the University of Washington reported an exciting development for the field of astrophysics and the search for extraterrestrial intelligence (SETI), using observations from the Transiting Exoplanet Survey Satellite (TESS) mission to monitor the SETI Ellipsoid, a method for identifying potential signals from advanced civilizations in the ...
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