Growing number of hypothyroidism patients receiving treatment other than levothyroxine
2023-06-16
The use of thyroid hormones other than the commonly prescribed hormone medicine levothyroxine to treat hypothyroidism, or underactive thyroid, is increasing, according to a study being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
“This is significant because the long-term health outcomes of these treatments are not as well known as levothyroxine,” said researcher Matthew Ettleson, M.D., of the University of Chicago in Chicago, Ill.
The thyroid makes the hormones triiodothyronine ...
Prevalence of metabolic associated fatty liver disease is increasing
2023-06-16
CHICAGO—The percent of metabolic associated fatty liver disease (MAFLD), the leading global cause of liver disease, is increasing in U.S. adults, according to a study presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Mexican Americans consistently had the highest percentage of MAFLD, especially in 2018, although the prevalence of increase was higher among Whites, the study found.
MAFLD, previously known as non-alcoholic fatty liver disease (NAFLD), is fast becoming the most common indication ...
The global human day – A bird’s eye perspective
2023-06-16
Everyone has 24 hours per day. Across the global population of 8 billion people this adds up to approximately 190 billion human hours per day. How those hours are spent determines the impacts we have on our surroundings as well as how we experience life. To find out how people around the world use their time, a research team led by McGill University has gathered and analyzed information about both economic and non-economic activities in order to estimate, for the first time, what a day in the life of the world looks like.
“At present, we are struggling to come to terms with global challenges, and that calls for fresh perspectives on how the world ...
Planned reform of EU pharmaceutical legislation: early market access and robust evidence need not be a contradiction
2023-06-16
The European Commission's stated aim is to improve access to innovative drugs at the national level throughout the EU. Firstly, according to the proposal for the reform of EU pharmaceutical legislation, there are still considerable differences in access between countries. Secondly, drug development has so far only been geared to a limited extent to the actual needs of patients. According to the German Institute for Quality and Efficiency in Health Care (IQWiG), the latter point is in line with the perspective of the ...
Dads are key in supporting breastfeeding, safe infant sleep
2023-06-16
Findings highlight racial disparities in sudden unexpected infant death in the U.S.
Only 16% fathers followed all three AAP-recommended infant sleep practices
Rates of breastfeeding initiation and breastfeeding at eight weeks were much higher among fathers who wanted their infant’s mother to breastfeed than those who did not or had no opinion
CHICAGO --- Fathers can make a huge difference in whether an infant is breastfed and placed to sleep safely, according to a recent survey of new fathers led by scientists at Northwestern University and the Ann & Robert H. Lurie Children’s Hospital of Chicago.
The study included 250 fathers who ...
AI could replace humans in social science research
2023-06-16
In an article published yesterday in the prestigious journal Science, leading researchers from the University of Waterloo, University of Toronto, Yale University and the University of Pennsylvania look at how AI (large language models or LLMs in particular) could change the nature of their work.
“What we wanted to explore in this article is how social science research practices can be adapted, even reinvented, to harness the power of AI,” said Igor Grossmann, professor of psychology at Waterloo.
Grossmann and colleagues note ...
Research hints at how fungus farming ants keep their gardens healthy
2023-06-16
‘Weed early and often’ is the key to a productive garden. Interestingly, certain species of ants are also avid gardeners, a practice they’ve refined over 50 million years. They too weed their underground fungus gardens, but how they know what to weed out has been a mystery. Now, a multidisciplinary team of scientists report in PNAS on June 15 how ants distinguish the good fungus from the bad.
People rely on sight to identify weeds but ants grow fungus underground in the dark and must have other ways to sense undesirable garden denizens. A team led by Jonathan Klassen, Ph.D., at the ...
Impacts of elevated salinity on microbial interactions within activated sludge microbial community: RMT-based network analysis
2023-06-16
Biological treatment processes are critical for sewage purification, wherein microbial interactions are tightly associated with treatment performance. Previous studies have focused on assessing how environmental factors (such as salinity) affect the diversity and composition of the microbial community but ignore the connections among microorganisms. To fill this gap, an international team of researchers conducted an in-depth analysis of microbial interactions at elevated salinity in activated sludge systems.
Biological ...
Rice University chemist leverages heterogeneity for insight into catalysis, cancer initiation
2023-06-16
HOUSTON – (June 16, 2023) – Rice University chemist Anatoly Kolomeisky has won an award from the National Science Foundation to investigate how heterogeneity affects chemical and biological processes. The goal of his project is to develop analytical models that quantify the role of heterogeneity in various phenomena including catalytic reactions, antimicrobial peptides, early cancer development and lysis, a process describing cellular membrane breakdown.
“We live in a world of heterogeneity,” ...
Significant correlation found between vitreous human biomarkers and Alzheimer’s disease
2023-06-16
BOSTON – New research from Boston Medical Center found a significant correlation between biomarkers in the vitreous humor of the eye and pathologically confirmed cases of Alzheimer’s disease (AD) and Chronic Traumatic Encephalopathy (CTE) in post-mortem brain and eye tissue. Published in IOS Press, this exploratory study indicates that biomarkers in the vitreous humor may serve as a proxy for neuropathological disease.
The incidence of dementias like AD continues to rise. As of 2021, 6.2 million North Americans above 65 years of age are suffering from AD, and this number is projected to reach 13.2 million by 2060. Diagnosis of both AD and CTE is based on symptoms, clinical exam ...
Brigid Garelik named Chief Medical Officer of the Children’s Tumor Foundation
2023-06-16
The Children’s Tumor Foundation (CTF) has announced that Brigid Garelik, MD, MPH, has been appointed Chief Medical Officer, overseeing the Foundation’s research and clinical initiatives. In this role, Dr. Garelik will set direction for the Foundation’s innovative R&D programs, developing effective clinical and preclinical strategies in order to deliver treatments to patients. She will also direct the Foundation’s educational programs in support of NF healthcare professionals, growing the NF field, and R&D related patient engagement. She will report to the President of the Children’s Tumor Foundation, Annette Bakker, PhD.
Dr. Garelik is an accomplished ...
Launch of REC@NUS Corporate R&D Laboratory for Next Generation Photovoltaics
2023-06-16
A new SGD 77 million research initiative has been launched today at the National University of Singapore (NUS) to boost innovation and research on advanced solar cell technologies in Singapore. Over the next five years, the REC@NUS Corporate R&D Laboratory for Next Generation Photovoltaics (REC@NUS Corp Lab), which is jointly set up by the Solar Energy Research Institute of Singapore (SERIS) at NUS and REC Solar (REC), will research, develop, and commercialise disruptive solar photovoltaic (PV) technologies based on perovskite-silicon tandem solar cells.
Supported ...
Study finds combustion from gas stoves can raise indoor levels of chemical linked to a higher risk of blood cell cancers
2023-06-16
A chemical linked to a higher risk of leukemia and other blood cell cancers creeps into millions of homes whenever residents light their gas stoves. A new Stanford-led analysis finds that a single gas cooktop burner on high or a gas oven set to 350 degrees Fahrenheit can raise indoor levels of the carcinogen benzene above those in secondhand tobacco smoke. Benzene also drifts throughout a home and lingers for hours in home air, according to the paper published June 22 in Environmental Science & ...
Fossil study sheds light on famous spirals found in nature
2023-06-16
Leaf arrangements in the earliest plants differ from most modern plants, overturning a long-held theory regarding the origins of a famous mathematical pattern found in nature, research shows.
The findings indicate that the arrangement of leaves into distinctive spirals, that are common in nature today, were not common in the most ancient land plants that first populated the earth’s surface.
Instead, the ancient plants were found to have another type of spiral. This negates a long held theory about the evolution of plant leaf spirals, indicating that they evolved ...
Racial disparities in lung cancer screening among veterans
2023-06-16
About The Study: The results of this study suggest that Black veterans have lower rates of lung cancer screening that are not fully explained by demographic and socioeconomic variables, underscoring the need for further qualitative studies on barriers to lung cancer screening as well as evidence-based interventions targeted to Black veterans.
Authors: Neelima Navuluri, M.D., M.P.H., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.
To access the embargoed study: ...
Experiences of clinicians contending with health care resource scarcity during COVID-19
2023-06-16
About The Study: The findings of this qualitative study suggest that institutional plans to protect frontline clinicians from the responsibility for allocating scarce resources may be unworkable, especially in a state of chronic crisis. Efforts are needed to directly integrate frontline clinicians into institutional emergency responses and support them in ways that reflect the complex and dynamic realities of health care resource limitation.
Authors: Catherine R. Butler, M.D., M.A., of the University of Washington in Seattle, ...
When is migration successful adaptation to climate change?
2023-06-16
A new study by an international team from Africa, Asia and Europe has put forward three criteria for evaluating the success of migration as adaptation in the face of climate change: well-being, equity and sustainability.
The study shows that while migration is increasingly recognised as an effective way to deal with climate risks, or a form of adaptation, it is far from a silver-bullet solution.
For example, remittances – which include flows of money, ideas, skills and goods between migrants and their places of origin – are thought to be key to facilitating adaptation to climate change.
But, drawing on evidence from every continent ...
CityU researchers invent a low-temperature synthesis method for high-quality tellurium nanomesh for next-generation electronics
2023-06-16
A collaborative team led by researchers from City University of Hong Kong (CityU) recently invented an innovative method for synthesizing high-quality, semiconducting nanomesh at a lower temperature and production cost than conventional methods. The findings will help enable the large-scale production of nanomesh for next-generation electronics.
Nanomesh is a nano-scale material formed from a network of nanowires. For several decades, one-dimensional materials like nanowires made of crystalline inorganic materials have been widely explored as the main driver for emerging electronics, as they have features like mechanical flexibility, ...
Endocrine Society Scientific Statement distinguishes normal aging from endocrine disease
2023-06-16
CHICAGO—A new Scientific Statement released today by the Endocrine Society highlights the differences between aspects of aging that are normal and sometimes over-treated, and those such as menopausal symptoms and osteoporosis that can be treated and deserve more attention.
“Hormones and Aging: An Endocrine Society Scientific Statement,” reviews the current state of research on hormonal changes with age. The statement focuses on common endocrine-related changes in older people including menopause and the development ...
Continuous vs intermittent meropenem administration in critically ill patients with sepsis
2023-06-16
About The Study: In critically ill patients with sepsis, compared with intermittent administration, the continuous administration of the antibiotic meropenem did not improve the composite outcome of mortality and emergence of pandrug-resistant or extensively drug-resistant bacteria at day 28.
Authors: Giovanni Landoni, M.D., of the IRCCS San Raffaele Scientific Institute in Milan, Italy, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2023.10598)
Editor’s ...
Japan’s subtropical forests home to a newly discovered beetle species
2023-06-16
A new weevil species was discovered in Japan’s pristine subtropical forests on Ishigaki Island and Yanbaru National Park in Okinawa.
Renowned for their remarkable biodiversity, the Ryukyu Islands are a chain of subtropical islands distributed between mainland Japan and Taiwan that boast a relatively isolated evolutionary history, and are home to a distinctive and fascinating insect fauna.
Researchers at the Okinawan Institute of Science and Technology (OIST) have been placing net traps to monitor insects on Okinawa ...
Revolutionary new method can manipulate the shape and packing of DNA
2023-06-16
A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a single person, it would span a staggering distance – enough to reach the sun and back 60 times over. In order to manage such an astounding volume of biological information, the cell compacts its DNA into tightly packed chromosomes.
“Imagine DNA as a piece of paper upon which all our genetic information is written.” Says Minke A.D. Nijenhuis, co-corresponding author. “The paper is folded into a very tight structure in order to fit all of that ...
New insights on bacteria that causes food poisoning
2023-06-16
Recently, Providencia spp. which have been detected in patients with gastroenteritis, and similar to enterohemorrhagic Escherichia coli. O157 and Salmonella spp., have been attracting attention as causative agents of food poisoning. For children with low immunity, food poisoning can be lethal as it causes severe symptoms such as diarrhea and dehydration, so clarifying the source of infection and pathogenic factors of Providencia spp., and establishing preventive methods are urgent issues worldwide.
A joint research group led by Professor Shinji Yamasaki, Dr. Sharda Prasad Awasthi, a Specially Appointed Lecturer, and graduate ...
Alcohol and smoking to blame for premature deaths among night owls, 37-year study suggests
2023-06-16
Staying up late at night has little impact on how long ‘night owls’ live, according to new research published in the peer-reviewed journal Chronobiology International.
Data based on nearly 23,000 twins, however shows that evening types have a slightly increased risk of dying than morning types, but this is largely linked to smoking and drinking.
The study which tracked people over the course of more than 37 years in Finland suggests that lifestyle should be considered.
This is when analyzing the impact on health of chronotype – the body’s natural inclination to sleep at a certain time.
“Our ...
Removing barriers to commercialization of magnesium secondary batteries
2023-06-16
A research team led by Dr. Minah Lee of the Energy Storage Research Center at the Korea Advanced Institute of Science and Technology(KIST) has developed a chemical activation strategy of magnesium metal that enables efficient operation of magnesium batteries in common electrolytes that are free of corrosive additives and can be mass-produced.
While the demand for lithium-ion batteries is exploding due to the rapid growth of the electric vehicle and energy storage system(ESS) markets, the supply and demand of their raw materials such as lithium and cobalt ...
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