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Finding out you’re autistic in later life can be a positive experience

2023-06-15
Receiving an autism diagnosis in your 20, 30s, 40s, 50s or even 60s may seem daunting, but a new study from psychologists in Bath and London finds that the link between the age at which someone gets diagnosed has little bearing on their quality of life. So-called ‘late diagnosis’ for autism has hit the headlines recently thanks to autism campaigner Christine McGuiness. Whereas autism is usually diagnosed in childhood, it is increasing being diagnosed in adults and especially among women. Parents often wonder if their child finding out they are autistic earlier or later will have an impact on their lives in the long term. Whilst many people who discover they are autistic as adults ...

Rising rates of benzodiazepine toxicity among young people spark concern

Rising rates of benzodiazepine toxicity among young people spark concern
2023-06-15
Toronto, ON, June 15, 2023 – The rate of hospital encounters for benzodiazepine-related toxicity rose by 67 per cent for young adults (aged 19 to 24) and 44 per cent for youth (aged 18 or below) in Ontario between 2013 and 2020, according to a new study from ICES and Unity Health Toronto. Though there was an overall decline of 7 per cent in the provincial rate of benzodiazepine toxicity, this was largely driven by reductions in rates among people aged 35 years and older. Benzodiazepines are commonly prescribed to treat anxiety ...

How antelopes under threat from the climate crisis have responded to rising temperatures

2023-06-15
The climate crisis is turning the temperature up all over the world, but in southern Africa, the rise has been particularly concerning. Wild animals dependent on delicate ecosystems which are already dry, so that food and water scarcity limits their ability to cope with increased heat, are at serious risk. Scientists studied the behavior of three different species of antelope with overlapping ranges in Namibia to try to understand how animals of different sizes and behaviors adapt to the heat. “Even the indigenous wildlife, adapted to hot and arid conditions, shows sensitivity to extreme heat,” said Paul Berry of the University of Potsdam, lead author of the study in ...

Dialogues across language and culture

2023-06-15
Teacher talk seems intuitive – the expert imparts knowledge onto novices, who passively receive expertise like a car or machine receives parts at every station on an assembly line. In reality, an effective teacher in an era of dynamic and higher literacies is less of a factory worker and more of an active negotiator who tries to understand where their students are coming from in order to reach them. The language classroom amplifies this challenge where the negotiation not only centers on the knowledge itself but the means of communication for that knowledge. ...

Access to financial services linked to lower COVID mortality rates

Access to financial services linked to lower COVID mortality rates
2023-06-15
New research shows that some of the best tools to decrease COVID-19 mortality rates weren’t found in the ER, but rather at the bank. A study of COVID-19 mortality rates across 142 nations has demonstrated a surprisingly strong link between access to formal financial services and lower COVID-19 mortality rates. In fact, it’s proved to be as strong a predictor of lower COVID-19 death rates as several comorbidities are of higher COVID-19 death rates.  “The reduction is surprisingly large, similar in magnitude to, but opposite in direction from, the mortality risks associated with higher rates of lung cancer and hypertension,” says Todd Watkins, ...

Men died of overdose at 2-3 times greater a rate than women in the U.S. in 2020-2021

2023-06-15
Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing death records data from across the United States. The study found that men had a 2–3 times greater rate of overdose mortality from opioids (like fentanyl and heroin) and psychostimulants (like methamphetamine and cocaine). While it has been known that men use drugs at higher rates than women, the researchers found that this alone does not explain the gap in overdose deaths, noting that biological, behavioral, and social factors likely ...

A marine mystery: Discovering the link between climate change and sea sponge loss

A marine mystery: Discovering the link between  climate change and sea sponge loss
2023-06-15
Sea sponges are essential to marine ecosystems. They play critical roles in the ocean, as they provide shelter and food to a plethora of marine creatures, recycle nutrients by filtering thousands of litres of sea water daily, and are hosts to microbes that may be the key to some of the most pressing medical challenges we face today. Now, scientists from UNSW have discovered that when a tropical sea sponge is exposed to warmer temperatures, it loses an important microbe, which could explain why the sponge tissue dies. The latest study, published today in ISME Communications, has revealed that by exposing sea sponges ...

International expert panel revises management of concussion in sport for optimal care of athletes at all levels of participation

2023-06-15
Journals from BMJ Press Release: Embargoed 23:30 hours UK (BST) time Wednesday 14 June 2023 Please click on links for full articles and contact authors direct for further comment - details can be found under Notes for Editors. Please remember to credit the relevant journal - this assures your audience it is from a reputable source.     BRITISH JOURNAL OF SPORTS MEDICINE Externally peer reviewed? Yes Evidence type: Consensus Statement Subjects: People Latest Consensus Statement on Concussion in Sport includes: -New and updated age appropriate tools to aid identification ...

Machine-learning method used for self-driving cars could improve lives of type-1 diabetes patients

Machine-learning method used for self-driving cars could improve lives of type-1 diabetes patients
2023-06-15
The same type of machine learning methods used to pilot self-driving cars and beat top chess players  could help type-1 diabetes sufferers keep their blood glucose levels in a safe range. Scientists at the University of Bristol have shown that reinforcement learning, a type of machine learning in which a computer program learns to make decisions by trying different actions, significantly outperforms commercial blood glucose controllers in terms of safety and effectiveness. By using offline reinforcement learning, where the algorithm learns from patient records, the researchers improve ...

A plant-based, oral delivery of insulin regulates blood sugar levels similar to natural insulin

A plant-based, oral delivery of insulin regulates blood sugar levels similar to natural insulin
2023-06-15
Insulin production has, for the last 50 or so years, come with some risks to the patient. Even so, the medication is lifesaving for the estimated 537 million adults living with diabetes worldwide, with that number expected to grow. Recent clinical studies show that injection via insulin pens can cause insulin to reach the bloodstream so quickly that hypoglycemia, or blood sugar levels that dip below the healthy range, may result. Automated insulin pumps can deliver precise insulin and minimize this risk but are expensive and available only to a small portion of diabetes patients around the world. Now, a plant-based, oral delivery of proinsulin could address these drawbacks, ...

Nursing homes serving Black residents have greater hospitalizations, emergency department visits

2023-06-15
Staffing levels likely drive the differences in hospitalizations and emergency department visits among nursing homes, the researchers report in the Journal of the American Geriatrics Society. Studies show that nursing homes serving high proportions of Black residents may experience poor healthcare outcomes. To better understand the environmental and structural characteristics of nursing homes that may lead to these outcomes, the researchers examined data from 14,121 U.S. nursing homes using multiple ...

When materials discovery glitters

When materials discovery glitters
2023-06-14
By Rebekah Orton Thomas Edison famously tried hundreds of materials and failed thousands of times before discovering that carbonized cotton thread burned long and bright in an incandescent light bulb. Experiments are often time consuming (Edison’s team spent 14 months) and expensive (the winning combination cost about $850,000 in today’s money). Expenses and time increase exponentially when developing the quantum materials that will revolutionize modern electronics and computing. To make quantum material discovery possible, researchers turn to detailed databases as their virtual laboratory. A new database of understudied quantum materials ...

Just add sugar: Research shows common antioxidant can be more beneficial through glycosylation

Just add sugar: Research shows common antioxidant can be more beneficial through glycosylation
2023-06-14
New research shows that polyphenolic compounds, which are commonly found in fruits and vegetables, can be combined with sugar molecules to create potential life-saving drugs. Polyphenols are a class of compounds found in many plant-based foods. Polyphenols help prevent cellular damage in the body and can help to prevent diseases such as cancer or heart disease. However, many of them do not dissolve in water, making it difficult to fully take advantage of their health benefits. Biological Engineering Professor Jixun Zhan and his graduate students Jie Ren and Caleb Barton recently published a comprehensive ...

Dietary supplementation shown to improve nutrition biomarkers in study of older men

Dietary supplementation shown to improve nutrition biomarkers in study of older men
2023-06-14
CORVALLIS, Ore. – A six-month study of healthy older men demonstrated that daily multivitamin/multimineral supplementation had a positive effect on key nutrition biomarkers. The research led by Oregon State University’s Tory Hagen and Alexander Michels also showed that the changes in nutrition status could have direct connections to cellular function, measured by the oxygen consumption of the study participants’ blood cells. The findings, published in the journal Nutrients, suggest that supplementation may be a key tool to help people stay healthier as they age. “Many older adults take ...

Remains at Crenshaw site are local, ancestors of Caddo, study finds

Remains at Crenshaw site are local, ancestors of Caddo, study finds
2023-06-14
Hundreds of human skulls and mandibles recovered from the Crenshaw site in southwest Arkansas are the remains of ancestors of the Caddo Nation and not foreign enemies, according to a new study published in the Journal of Archaeological Science. Collaborating with the Caddo Nation in Oklahoma, researchers at the University of Arkansas and Arkansas Archeological Survey tested lead and strontium isotopes in the teeth of human remains and compared them to ancient animal teeth from several surrounding regions to determine that the 700-year-old human remains were local ...

The Viking disease can be due to gene variants inherited from Neanderthals

The Viking disease can be due to gene variants inherited from Neanderthals
2023-06-14
Many men in northern Europe over the age of 60 suffer from the so-called Viking disease, which means that the fingers lock in a bent position. Now researchers at Karolinska Institutet, together with colleagues, have used data from over 7,000 affected individuals to look for genetic risk factors for the disease. The findings, which have been published in Molecular Biology and Evolution, show that three of the strongest risk factors are inherited from Neanderthals. Up to 30 percent of men in northern Europe over 60 suffer from ...

Further hope for base-edited T-cell therapy to treat resistant leukaemia

2023-06-14
Three young patients with relapsed T-cell leukaemia have now been treated with base-edited T-cells, as part of a ‘bench-to-bedside’ collaboration between UCL and Great Ormond Street Hospital for Children (GOSH). The data from the NHS clinical trial, published in The New England Journal of Medicine and funded by the MRC, shows how donor CAR T cells were engineered using cutting edge gene editing technology to change single letters of their DNA code so they could fight leukaemia. The experience of using the cells in three patients is shared, and includes 13-year-old Alyssa from Leicester, who last year was the first person in the world to ...

A new way to visualize force-sensing neurons

2023-06-14
A recent study by researchers at Texas Children’s Hospital, Baylor College of Medicine, and Scripps Research Institute has discovered fluorescent dye FM 1-43 as an effective and versatile tool to visualize PIEZO2 ion channel activity in mechanosensory neurons. The study, published in Neuron, was led by Dr. Kara Marshall, assistant professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, with Dr. Ardem Patapoutian, Nobel Laureate and professor at Scripps Research Institute. Mechanosensation is the ability ...

Study finds that proven medications for alcohol use disorder are rarely given to adolescents and young adults on public insurance

2023-06-14
BOSTON – Heavy drinking commonly begins in adolescence and is a known risk factor for the development of alcohol use disorder (AUD). Data from adult clinical trials suggest offering evidence-based medications for AUD to younger adults could promote their engagement in treatment and improve clinical outcomes. But are those medications being used when and where they are needed? In a review of claims data for youths insured by Medicated in 15 U.S. states, a team of researchers found that most youths with a diagnosis of AUD do not receive medications as part of their therapy, despite ...

Phosphate, a key building block of life, found on Saturn’s moon Enceladus

Phosphate, a key building block of life, found on Saturn’s moon Enceladus
2023-06-14
An international team including a University of Washington scientist has found that the water on one of Saturn’s moons harbors phosphates, a key building block of life. The team led by the Freie Universität Berlin used data from NASA’s Cassini space mission to detect phosphates in particles ejected from the ice-covered global ocean of Saturn’s moon Enceladus. Phosphorus, in the form of phosphates, is vital for all life on Earth. It forms the backbone of DNA and is part of cell membranes and bones. The new study, published June 14 in ...

Conflict in marriage less harmful for kids when dad keeps it constructive

Conflict in marriage less harmful for kids when dad keeps it constructive
2023-06-14
URBANA, Ill. — Conflict is unavoidable in all marriages. When it erupts in families with children, stressed or angry parents may take their pain out on the kids, projecting their anger or withdrawing emotionally or physically. In the worst cases, children’s socioemotional development can suffer. But the way parents, especially fathers, deal with marital conflict can make a difference to kids, according to a new study from researchers at the University of Illinois Urbana-Champaign. “In the past, marital conflict ...

Ten ways to increase Latino participation in Alzheimer’s research from leaders in health equity science

2023-06-14
CHICAGO, June 14, 2023 -- Leaders in health equity have issued an urgent call to address the underrepresentation of U.S. Latinos in Alzheimer's and dementia clinical trials. Their recommendations are outlined in an article published online today by Alzheimer's & Dementia: Translational Research & Clinical Interventions.   “A call to address structural barriers to the representation of Hispanics/Latinos in clinical trials on Alzheimer's disease and related dementias: A micro-meso-macro perspective,” was led by first author María P. Aranda, ...

National economies recover faster when countries are powered by renewable energy – new research

2023-06-14
National economies recover significantly faster from shocks when countries are powered by renewable energy sources, according to new research that has profound implications for global energy policy. Researchers from Trinity College Dublin looked for patterns in data from 133 systemic economic crises that affected 98 countries over a 40-year span. And while their analyses show that countries relying on a broader range of energy sources experience longer recovery times, the best predictor of economic recovery was the extent to which a country relied on renewable energy. Underlining the significance of the finding is the fact that while data ...

A machine learning approach to freshwater analysis

A machine learning approach to freshwater analysis
2023-06-14
From protecting biodiversity to ensuring the safety of drinking water, the biochemical makeup of rivers and streams around the United States is critical for human and environmental welfare. Studies have found that human activity and urbanization are driving salinization (increased salt content) of freshwater sources across the country. In excess, salinity can make water undrinkable, increase the cost of treating water, and harm freshwater fish and wildlife. Along with the rise in salinity has also been an increase in alkalinity over time, and past research suggests that salinization may enhance alkalinization. But unlike excess salinity, ...

Inflammatory bowel disease linked to increased risk of stroke

2023-06-14
MINNEAPOLIS – People with inflammatory bowel disease (IBD) are more likely to have a stroke than people without the disease, according to a study published in the June 14, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that IBD causes stroke; it only shows an association. Inflammatory bowel disease causes chronic inflammation of the intestines. It includes Crohn’s disease, ulcerative colitis and unclassified inflammatory bowel disease. The study found that people with IBD were 13% more likely to have a stroke up to ...
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