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Colchicine fails to reduce primary outcomes in COP-AF trial but encouraging signals found

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023: Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.1 Perioperative AF occurs in approximately 10% of patients after major thoracic surgery, while MINS has an incidence of about 20% in the same patient population.2 Patients with perioperative AF and MINS have a poor prognosis.3,4 High levels ...

First ESC Guidelines covering all acute coronary syndromes published today

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023:  The European Society of Cardiology (ESC) Guidelines on acute coronary syndromes are published online today in European Heart Journal.1 The document covers the management of unstable angina and all types of acute myocardial infarction. “Time is critical in acute coronary syndromes. When an artery supplying the heart with blood becomes blocked, the quicker we open the artery and restore flow, the less damage occurs to the heart muscle,” said Guidelines task force ...

First international guidelines on heart muscle diseases published today

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023:  The European Society of Cardiology (ESC) Guidelines on cardiomyopathies are published online today in European Heart Journal.1 This is the first international guideline document to include all cardiomyopathy subtypes, and the first time that specific recommendations are made for cardiomyopathies other than hypertrophic cardiomyopathy. “This pioneering document reflects the advances in genetics and cardiac imaging and the advent of new treatments that target specific causes of disease,” said Guidelines task force chairperson Dr. Elena Arbelo of the Hospital Clinic, University of Barcelona, Spain. “At the ...

Recommendations to reduce cardiovascular risk in patients with diabetes published today

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023:  Patients with type 2 diabetes are more than twice as likely to develop cardiovascular disease (CVD) than their healthy peers. Advice to lower that risk is launched today in the 2023 European Society of Cardiology (ESC) Guidelines for the management of cardiovascular disease in patients with diabetes, published in European Heart Journal.1 “Patients with type 2 diabetes have a two- to four-fold higher risk of coronary artery disease, stroke, heart failure, atrial fibrillation and peripheral artery disease compared to those without type 2 diabetes and when CVD occurs, the prognosis ...

Patients urged to be vigilant about cardiac infections

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023:  Patients with specific cardiac conditions such as valvular heart disease and congenital abnormalities, or those requiring a pacemaker, should practice good dental and skin hygiene to help prevent rare but potentially deadly infections of the heart’s inner lining and valves, according to European Society of Cardiology (ESC) Guidelines on infective endocarditis, published online today in European Heart Journal.1 “Infective endocarditis is an uncommon but very serious disease that can present with ...

Focused update of ESC Heart Failure Guidelines published today

2023-08-25
Amsterdam, Netherlands – 25 Aug 2023:  A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines is published online today in European Heart Journal following the results of major new trials that should change the management of patients with heart failure.1 “Heart failure is a fast-moving area of research and exciting new trials are expanding the treatment options for patients,” said Guidelines task force chairperson Professor Theresa McDonagh of King’s College Hospital, London, UK. “This focused update incorporates the latest evidence-based treatments ...

Cancer drug development yesterday, today and tomorrow

Cancer drug development yesterday, today and tomorrow
2023-08-25
“One can expect that artificial intelligence (AI) will play some role in the future drug development.” BUFFALO, NY- August 25, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Cancer drug development yesterday, today and tomorrow.” In this new editorial, researchers Elzbieta Izbicka and Robert T. Streeper from New Frontier Labs discuss the history of cancer drug development and how it has evolved over time. The editorial also highlights the current state of cancer drug development and ...

How fast does the charge migrate in molecules?

How fast does the charge migrate in molecules?
2023-08-25
To discover how light interacts with molecules, the first step is to follow electron dynamics, which evolve at the attosecond timescale. The dynamics of this first step have been called charge migration (CM). CM plays a fundamental role in chemical reactions and biological functions associated with light–matter interaction. For years, visualizing CM at the natural timescale of electrons has been a formidable challenge in ultrafast science due to the ultrafine spatial (angstrom) and ultrafast temporal ...

AI analysis finds younger AFib patients benefit from MRI-guided ablation treatments

2023-08-25
Younger atrial fibrillation (AFib) patients are most likely to benefit from more personalized, MRI-guided ablation treatments to correct irregular heart rhythms, according to a new artificial intelligence-guided analysis of results from the DECAAF II trial, one of the largest global studies of treatments for heart arrhythmias. Tulane University researchers presented the findings at the European Society of Cardiology (ESC) Congress 2023 in Amsterdam this week. There’s been debate among physicians on whether going beyond traditional ablation treatments provides a benefit to patients. In 2021, the ...

European Society of Cardiology calls for competency-based cardiac imaging

2023-08-25
Sophia Antipolis, 25 August 2023:  Competency-based cardiac imaging delivery is needed for effective and efficient patient care, according to a European Society of Cardiology (ESC) statement published today in European Heart Journal, a journal of the ESC.1 All seven ESC subspeciality associations have endorsed the document, namely the European Association of Cardiovascular Imaging (EACVI), Association of Cardiovascular Nursing & Allied Professions (ACNAP), Association for Acute CardioVascular Care (ACVC), European Association of Preventive Cardiology (EAPC), European Association ...

Understanding the surge in cannabis use among pregnant and postpartum women in the US

2023-08-25
Pregnant and recently postpartum women who suffer with mental health disorders may be vulnerable to using cannabis to self-medicate, according to a Rutgers-led study.   In a nationally representative survey, Qiana L. Brown, an assistant professor at the Rutgers School of Social Work, examined the relationship between mental health disorders, cannabis use and cannabis use disorder (CUD) among pregnant and postpartum women in the US. The findings were published online in advance of print in the July 2023 issue of the journal Drug and Alcohol Dependence.   “Before this study, we ...

A study to keep downtown Arlington vibrant

A study to keep downtown Arlington vibrant
2023-08-25
A study led by two University of Texas at Arlington public affairs professors, in partnership with city leaders, suggests downtown Arlington events would enjoy increased attendance if there were more parking, shaded areas and Instagram-ready photo opportunities. Respondents to the survey consider downtown Arlington one of the top-three destinations in the city for entertainment. “Downtown is competing with Texas Live! and The Highlands,” said Emily Nwakpuda, assistant professor in UTA’s College of Architecture, ...

The recovery of European freshwater biodiversity stops, urgent action needed

The recovery of European freshwater biodiversity stops, urgent action needed
2023-08-25
Freshwater ecosystems hold significant significance in the context of global biodiversity. These water bodies provide habitat for numerous plant and animal species, and they play a crucial role in maintaining food chains and preserving ecological balance. Mitigation measures including wastewater treatment and hydromorphological restoration have historically shown promise in improving environmental quality and supporting the recovery of freshwater biodiversity. Together with a large international team the study’s first author, Prof. Dr. Peter Haase of the Senckenberg ...

JAXA, NASA XRISM Mission ready for liftoff

JAXA, NASA XRISM Mission ready for liftoff
2023-08-25
A powerful satellite called XRISM (X-ray Imaging and Spectroscopy Mission) is set to provide astronomers with a revolutionary look at the X-ray sky. XRISM, led by JAXA (Japan Aerospace Exploration Agency) in collaboration with NASA and with contributions from ESA (European Space Agency), is scheduled to launch on an H-IIA rocket from Japan’s Tanegashima Space Center at 8:26 p.m. EDT on Sunday, Aug. 27 (9:26 a.m. on Monday, Aug. 28, in Japan). JAXA will stream the launch live ...

Women with undiagnosed endometriosis visit the doctor more frequently

Women with undiagnosed endometriosis visit the doctor more frequently
2023-08-25
Endometriosis is a chronic – often painful – illness that only affects women. New research shows potential for shortening the path to diagnosis and treatment. In the years prior to being diagnosed with endometriosis, women with the chronic illness have more contact than average with their GP, private gynaecologist and the hospital service. Researchers analysed 129,696 Danish women's utilisation of the healthcare sector, with particular focus on the 21,616 women who were diagnosed with endometriosis between 2000 and 2017. "We can see that ...

Soils forming on the branches of trees are an overlooked forest habitat

Soils forming on the branches of trees are an overlooked forest habitat
2023-08-25
In certain trees, soils can form along branches and can support varied plant and animal life. However, what conditions these ‘canopy soils’ form in, and what kind of biodiversity they support, has been difficult to study. Now, researchers from Utah State University and Imperial College London have surveyed dozens of trees in Costa Rica, mapping the canopy soils to determine where they form and how they might be affected by a changing climate. The results are published in Geoderma. First author Jessica Murray, from Utah State University, said: “We found canopy soils most often form in cool, foggy areas in these tropical forests ...

How local communities depend on the ivory palm tree in coastal Ecuador

How local communities depend on the ivory palm tree in coastal Ecuador
2023-08-25
URBANA, Ill. – The ivory palm tree, also known as tagua, is endemic to the Chocó-Darien region on the Pacific coast of South America. The local population relies on this unique tree for many uses and the tagua fruit, nuts, and leaves provide materials for a range of products. Two studies from the University of Illinois Urbana-Champaign and Pontificia Universidad Católica del Ecuador (PUCE) explore the ecosystem services provided by tagua in coastal Ecuador. The ivory palm is considered a threatened species as 98% of forest land in western Ecuador has been cleared, although current conservation ...

Grant to help students continue research in nematodes

Grant to help students continue research in nematodes
2023-08-25
Kennesaw State University biology professor Brandon Carpenter was inspired to pursue a career in science because of an undergraduate research experience. With a recent grant from the National Institutes of Health (NIH), he’ll provide a similar experience to his students. Carpenter, an assistant professor of cellular and molecular biology who studies neurodevelopmental  disorders and genetic mutations, received a $432,000 grant to continue research that will help uncover the mechanisms that regulate inheritance of ...

Move over pythons: These snakes are the real champion eaters

Move over pythons: These snakes are the real champion eaters
2023-08-25
Pythons have huge appetites, but which snake would win an eating contest? Surprisingly, it’s a harmless little African snake that consumes eggs whole like an amuse-bouche. Biologist Bruce Jayne at the University of Cincinnati discovered that this species, Dasypeltis gansi, can consume bigger prey relative to its own length and mass than even Burmese pythons, among the most massive snakes on Earth. “They probably would hold the Guinness world record,” said Jayne, a professor of biological sciences in UC’s College of Arts and Sciences. “It’s spectacular but on a small scale,” he said. ...

Families with a team mindset strengthened their bonds during COVID-19 pandemic

Families with a team mindset strengthened their bonds during COVID-19 pandemic
2023-08-25
Despite reports of families disintegrating under the hardships and constraints of the COVID-19 pandemic, a new study suggests that many families may have formed stronger bonds instead. One key difference between families that emerged from the pandemic stronger and unified compared with those that struggled was having a cohesive, family-oriented mindset. Families in which individuals perceived themselves as members of a team who were working for their collective benefit and found personal fulfillment in meeting the wants and needs of the other members were more likely to improve their ...

New human cell-based 3D model reveals insights into how immune cells contribute to Alzheimer’s disease

2023-08-25
Key Takeaways Researchers developed a new 3D model of Alzheimer’s Disease that allows them to study the role of immune cells in the disease They found that infiltration of immune cells significantly increases in brains with AD pathology and contributes to neurodegeneration and neuroinflammation The team also identified potential strategies to halt this process, which could lead to the development of new therapies BOSTON – Cognitive decline associated with Alzheimer’s disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive ...

Spending on mental health services has risen by more than 50% since beginning of pandemic

2023-08-25
Spending on mental health services among Americans with private health insurance has surged since the beginning of the COVID-19 pandemic, continuing to rise even as the use of telehealth has plateaued, according to a new study.   Spending on mental health services rose by 53% from March 2020 to August 2022 among a large group of people with employer-provided insurance, according to researchers from the RAND Corporation and Castlight Health. During the same period, use of mental health services increased by 39%.   The researchers say it is uncertain if the trend will continue since some rules that expanded payment for telehealth ...

Patient experiences with hospitals worsened during first two years of pandemic

2023-08-25
The experiences of patients hospitalized during the COVID-19 pandemic was significantly worse than in the years before the crisis, with hospitals with higher staffing levels holding on to better scores longer, according to a new RAND Corporation study.   Patients particularly reported worse staff responsiveness and hospital cleanliness, possibly reflecting staffing shortages in the hospital workforce and the effects of protocols needed to limit the spread of COVID-19, according to researchers.   Deficits were largest for hospitals that in the pre-pandemic period were lower-performing and had lower staffing levels. ...

Changes in patient experiences of hospital care during the pandemic

2023-08-25
About The Study: The results of this study suggest that higher-staffed and higher-performing hospitals were more resilient to the conditions of the COVID-19 pandemic, but by late 2021, patients’ experience of care had declined in all hospitals.  Authors: Marc N. Elliott, Ph.D., of the RAND Corporation in Santa Monica, California, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2023.2766) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

COVID-19 pandemic and associated inequities in heart attack treatment, outcomes

2023-08-25
About The Study: This study found that while the pandemic was associated with worse treatment and outcomes in patients with acute myocardial infarction (AMI; heart attack), race and ethnicity–associated inequities did not increase significantly. These findings suggest the need for additional efforts to mitigate outcomes associated with the COVID-19 pandemic for patients admitted with AMI when the hospital COVID-19 burden is substantially increased.  Authors: Laurent G. Glance, M.D., of the University of Rochester ...
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