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Genetic tests unexpectedly find genes linked to heart disease — now what?

2023-03-27
Statement Highlights: As health care professionals, researchers and consumers increasingly use genetic testing, they are uncovering incidental genetic abnormalities, or variants, that are associated with cardiovascular diseases. The statement writing committee cautions that incidentally identified single gene variants may or may not be risk factors for disease, so it is important to interpret them correctly and cautiously. The new scientific statement offers a framework to support health care professionals in appropriately assessing individual genetic variants, communicating findings with patients and families, and, when ...

Biochar and energy from pyrolysis can pave the way for carbon-neutral agriculture in China

2023-03-27
Since the Paris Agreement to combat global warming was reached in 2015, many countries have committed to becoming climate neutral, i.e., achieving net-zero greenhouse gas emissions. The world's largest agricultural country, China, is also committed to join the green transition. As the largest agricultural country, China is also the world's biggest emitter of greenhouse gases, yet it has set itself a target of achieving carbon neutrality by 2060.  According to Professor and Head of Land-CRAFT at Department of Agroecology at Aarhus University Klaus Butterbach-Bahl, this places huge demands on agricultural systems: "Agriculture in China accounts ...

Two striking new species of carnivorous plants discovered in the Andes of Ecuador

Two striking new species of carnivorous plants discovered in the Andes of Ecuador
2023-03-27
A team of botanists from Ecuador, Germany, and the United States has described two new species of carnivorous plants with striking appearance. They are part of the butterworts (genus Pinguicula), a group of flowering plants with about 115 species that can catch and digest small insects with their sticky leaves. Whereas the majority of butterwort species is distributed in the northern hemisphere, these new species were discovered in the high Andes of southern Ecuador, close to the border with Peru. Carnivorous plants use animals (usually small insects) as an additional source of nutrients ...

Global population could peak below 9 billion in 2050s

Global population could peak below 9 billion in 2050s
2023-03-27
The new projection is significantly lower than several prominent population estimates, including those of the United Nations. The researchers go further to say that if the world takes a “Giant Leap” in investment in economic development, education and health then global population could peak at 8.5 billion people by the middle of the century. The new projections by researchers from the Earth4All initiative for the Global Challenges Foundation is published as a working paper People and Planet, 21st Century Sustainable Population Scenarios and Possible Living Standards Within Planetary Boundaries. The team used a new system ...

Looking from different perspectives! Proper electronic structure of near-infrared absorbing functional dyes discovered

Looking from different perspectives! Proper electronic structure of near-infrared absorbing functional dyes discovered
2023-03-27
Near-infrared light, whose wavelength is longer than visible light, is invisible and can pass through many substances. Organic materials that efficiently absorb near-infrared light are essential for technological innovations that utilize near-infrared light, such as the dyes in the infrared blocking filters of smartphone cameras and security inks. These and many more technical applications make developing new dyes that can absorb longer wavelengths of near-infrared light desirable. Previously, near-infrared absorbing organic materials were treated as closed-shell molecules without unpaired electrons. However, a joint research group led by Associate Professor Takeshi Maeda, Assistant Professor ...

Bodies of people with mental illness are biologically older than their actual age

2023-03-27
New research shows that people with a lifetime history of mental disorders such as depression, bipolar disorder, or anxiety disorders have blood markers suggesting that they are older than their actual age. This may go some way to explaining why people with mental health problems tend to have shorter lifespans and more age-related diseases than the general population. Dr Julian Mutz and Prof Cathryn Lewis, from King’s College London, looked at data on 168 different blood metabolites from 110,780 participants in the UK Biobank2. They linked these data to information on whether individuals had a history of mental illness and found that those with a mental illness ...

Study identifies two promising molecular targets for drug development in recurrent and metastatic cervical cancer

2023-03-27
NRG Oncology GOG-0240 is the phase 3 randomized trial which demonstrated that the incorporation of bevacizumab with chemotherapy resulted in a statistically significant and clinically meaningful survival benefit for women with recurrent and metastatic cervical carcinoma (NCT00803062). GOG-0240 was a proof of concept in anti-angiogenesis therapy and a proof of principle in supportive care and led directly to an indication for bevacizumab in this disease in over 60 countries. Whole genome sequencing and whole exome sequencing of tumor samples obtained in GOG-0240 suggest that ARID1A and PIK3CA could represent potential targets ...

'Nano inks' could passively control temperature in buildings, cars

Nano inks could passively control temperature in buildings, cars
2023-03-27
World-first ‘phase change inks’ that could transform how we heat and cool buildings, homes and cars – to achieve sophisticated ‘passive climate’ control – have been developed, with enormous potential to help reduce energy use and global greenhouse gas emissions. New research published in The Royal Society of Chemistry’s Journal of Materials Chemistry A led by Dr Mohammad Taha, documents proof-of-concept ‘phase change inks’ that use nanotechnology to control temperature in everyday environments. They achieve this by adjusting the amount of radiation that can pass through ...

Project helps thousands of people in England and France into employment and entrepreneurship

2023-03-27
New research led by the University of East Anglia (UEA) shows that large infrastructure projects which are the focus of the UK government’s levelling up agenda and include support for business start-ups, must also offer sustainable, local investment in deprived communities. Through place-based micro-enterprise training and employment support over a longer time frame, lasting local impact can be demonstrated, according to the study’s policy recommendations. Supporting people to return to their communities, increasing social cohesion within them, boosting digital literacy and enabling net zero jobs are also likely to play a role. These goals can be easily ...

Embryos’ development is delayed in pregnancies that end in miscarriage

Embryos’ development is delayed in pregnancies that end in miscarriage
2023-03-27
Embryos in pregnancies that end in miscarriage take longer to develop in the womb than those in pregnancies that result in live births, according to new research published today (Monday) in Human Reproduction [1], one of the world’s leading reproductive medicine journals.   For the first time, researchers in The Netherlands have been able to look at the way embryos develop while pregnancies are ongoing. They used state-of-the-art imaging technology, including 3D ultrasound with high resolution transvaginal probes and ...

Global analysis of coronavirus protein research reveals how countries respond to disease

Global analysis of coronavirus protein research reveals how countries respond to disease
2023-03-27
In a new study, researchers examined how a country’s number of published 3D protein structures for coronaviruses, including the one responsible for COVID-19, correlated with its economic output and population. The findings reveal important insights into how different countries' research establishments respond to disease outbreaks and could be useful for planning responses to future pandemics.   The study showed that countries with larger economies generated more 3D structure determinations for the protein components ...

Shh! Intensive care incubators resonate sounds and risk damage to premature babies’ hearing, scientists say

2023-03-27
For vulnerable premature babies, an incubator in the neonatal intensive care unit (NICU) is a lifesaver, but the consequences can last a lifetime. Many studies have shown that the NICU is a noisy environment and that babies who spend time there have higher rates of hearing impairment, which can lead to delays in language acquisition. Scientists from Vienna, Hamburg, Munich, and Osnabruck set out to investigate the role of the incubator, an underestimated element in the soundscape that surrounds babies during their time in the NICU. “The ...

Securing new metal 3D printing technology that drives the renaissance of the manufacturing industry!

Securing new metal 3D printing technology that drives the renaissance of the manufacturing industry!
2023-03-27
□ A research team led by Dr. Sang-woo Song, Dr. Chan-kyu Kim, Dr. Kang-myung Seo at the Department of Joining Technology of the Korea Institute of Materials Science(KIMS), a government-funded research institute under the Ministry of Science and ICT, has developed a foundational technology for controlling the volume of molten metal in the process of 3D printing metal using welding techniques. They achieved this through collaborative research with a research team led by Professor Young-tae Cho and Professor ...

Advanced technologies for longer-lasting electric vehicles

Advanced technologies for longer-lasting electric vehicles
2023-03-27
Owing to the worldwide trend of utilizing electric vehicles, there has been a rise in demand for next-generation secondary batteries with higher capacity and faster charging than the lithium-ion batteries currently in use. Lithium metal batteries have been recognized as promising rechargeable batteries because lithium metal anode exhibits theoretical capacity 10 times higher than commercial graphite anode. During charging-discharging processes, however, lithium dendrites grow on the anode, leading to poor battery performance and short-circuit. Dr. Sungho Lee, Head of the ...

The genetics of temperature adaptation: how does life thrive in extreme conditions?

The genetics of temperature adaptation: how does life thrive in extreme conditions?
2023-03-27
The history of the Earth has been one of physical extremes—extreme atmospheric conditions, extreme chemical environments, and extreme temperatures. There was a time when the Earth was so hot all the water was vapor, and the first rain only fell once the planet cooled enough. Soon after, life emerged and through it all, life has found a way. Today life is found almost everywhere on Earth we have looked; it is difficult to find places where life does not exist. The remarkable ability of life to adapt to variable conditions is one of its defining characteristics. Of its many adaptations, the ability of life to adapt to varying temperatures ...

Opening up a different conversation about violence

Opening up a different conversation about violence
2023-03-27
20 years on from the invasion of Iraq, nearly 25 years since the Good Friday Agreement in Northern Ireland, and in the midst of war in Ukraine and contested questions about migration and the legacies of war, a brand new Centre for the Study of Violence will launch this week at the University of Bath. Led by academics across the University’s Faculty of Humanities & Social Sciences, including political theorists, development and humanitarian scholars, plus crime, defence and security experts, the new Centre will be the first of its kind in the UK. It aims to help society rethink how violence operates and to find ways to imagine a more peaceful world. The Centre ...

Students who played sports before the pandemic did better during lockdowns

2023-03-27
A history of participating in campus recreational sports can offset stress and contribute to academic competence even during high-stress periods such as a pandemic lockdown, shows a new study. Researchers at the University of Waterloo found that participation in activities such as fitness classes and intramural and drop-in sports before the pandemic was linked to lower levels of stress and higher levels of perceived competence to handle challenges and master school workload during the lockdown.  The study used factor and regression analyses based on self-reported ...

What do the elements sound like? (video)

What do the elements sound like? (video)
2023-03-26
INDIANAPOLIS, March 26, 2023 — In chemistry, we have He, Fe and Ca — but what about do, re and mi? Hauntingly beautiful melodies aren’t the first things that come to mind when looking at the periodic table of the elements. However, using a technique called data sonification, a recent college graduate has converted the visible light given off by the elements into audio, creating unique, complex sounds for each one. Today, the researcher reports the first step toward an interactive, musical periodic table. The researcher will present his results at the spring meeting of the American Chemical Society (ACS). ACS Spring 2023 is a hybrid meeting ...

Colorful films could help buildings, cars keep their cool

Colorful films could help buildings, cars keep their cool
2023-03-26
INDIANAPOLIS, March 26, 2023 — The cold blast of an air conditioner can be a welcome relief as temperatures soar, but “A/C” units require large amounts of energy and can leak potent greenhouse gases. Today, scientists report an eco-friendly alternative — a plant-based film that gets cooler when exposed to sunlight and comes in a variety of textures and bright, iridescent colors. The material could someday keep buildings, cars and other structures cool without requiring external power. The researchers will present their results at the spring meeting of the American Chemical Society (ACS). ACS Spring 2023 is a hybrid meeting being held virtually and in-person March 26–30 ...

New ways to measure curls and kinks could make it easier to care for natural hair

New ways to measure curls and kinks could make it easier to care for natural hair
2023-03-26
INDIANAPOLIS, March 26, 2023 — Black women and others with curly or kinky hair encounter a vast and confusing array of haircare options. Advice on the best products to use for a certain type of hair is often contradictory, and the results can be highly variable. Now, scientists are bringing order to this chaos by identifying properties such as the number of curls or coils in a given length of hair that could eventually help users pick the perfect product and achieve consistent results. The researchers will present their findings today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2023 is a hybrid meeting being held virtually and in-person ...

Two meteorites are providing a detailed look into outer space

2023-03-26
INDIANAPOLIS, March 26, 2023 — If you’ve ever seen a shooting star, you might have actually seen a meteor on its way to Earth. Those that land here are called meteorites and can be used to peek back in time, into the far corners of outer space or at the earliest building blocks of life. Today, scientists report some of the most detailed analyses yet of the organic material of two meteorites. They’ve identified tens of thousands of molecular “puzzle pieces,” including a larger amount of oxygen atoms than they had expected. The researchers will present their results at the spring meeting of the American Chemical Society ...

The more traumatic the childhood, the angrier the adult

2023-03-26
Scientists have found that depression and anxiety sufferers who have had a traumatic childhood tend to grow up as angry adults, and the worse the trauma, the angrier the adult. This can affect personal mental health and social interaction, but also makes it more difficult to treat the depression and anxiety. This work is presented at the European Congress of Psychiatry in Paris. Previously, the researchers had found that more than 40% of patients with both anxiety and depression had a tendency towards anger. This compares to only around 5% of healthy controls. The present ...

Scientists show that odors from other people’s sweat can help treat social anxiety

2023-03-26
A group of European researchers have shown that exposure to human odours, extracted from other people’s sweat, might be used to boost treatment for some mental health problems. In a preliminary study, the researchers were able to show that social anxiety was reduced when patients underwent mindfulness therapy while exposed to human ‘chemo-signals’, or what we commonly refer to as body odour, obtained from underarm sweat from volunteers.  Presenting the results of a pilot study at the European Congress of Psychiatry in Paris, lead researcher Ms Elisa Vigna, of the Karolinska Institute in Stockholm said: “Our state of mind causes us to produce molecules ...

Childhood trauma linked to adult mental health problems: women harmed more by abuse, men by neglect

2023-03-26
A new study shows that men and women are affected differently by childhood trauma: women are more affected by childhood emotional trauma and sexual abuse, whereas men are more affected by  childhood emotional and physical neglect. Lead researcher, Dr Thanavadee Prachason (from the University of Maastricht in the Netherlands) said, “Our findings indicate that exposure to childhood maltreatment increases the risk of having psychiatric symptoms in both men and women. However, exposure to emotionally or sexually abusive experiences during childhood increases the risk of a variety of psychiatric symptoms particularly ...

Is early rhythm control in atrial fibrillation care cost-effective?

Is early rhythm control in atrial fibrillation care cost-effective?
2023-03-26
Sophia Antipolis, 27 March 2023:  Patients with atrial fibrillation (AF) benefit from early rhythm control therapy. It reduces cardiovascular deaths, strokes, and other adverse outcomes by 20% compared to usual care. The beneficial effects of early rhythm control were shown by the pan-European EAST – AFNET 4 trial and confirmed by other large health studies. However, what is the price of the new treatment strategy? A cost-effectiveness analysis revealed: the health benefits of early rhythm control come at reasonable additional costs. The analysis was published today in EP Europace, a journal of the European ...
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