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Professor Guido Kroemer will inaugurate Redox Medicine 2023 by Highlighting the Hallmarks of Aging & Redox Medicine

Professor Guido Kroemer will inaugurate Redox Medicine 2023 by Highlighting the Hallmarks of Aging & Redox Medicine
2023-02-22
The 25th International Conference on Redox Medicine, on June 21-23 in Paris, will revolutionize tomorrow’s medicine through redox. The translation of basic knowledge of redox into molecular medicine will be extensively discussed. Prof. Guido Kroemer from the Université de Paris Cité, Hôpital Européen George Pompidou - AP-HP, is the key note speaker for this year. It is a great opportunity to share with Guido Kroemer his favorite topics and to have a unique moment of exchange with him.   Hallmarks of Aging & Redox Medicine: An Expanding Universe Prof. Kroemer will highlight the “hallmarks of ageing: genomic instability, ...

WVU physicists give the first law of thermodynamics a makeover

WVU physicists give the first law of thermodynamics a makeover
2023-02-22
West Virginia University physicists have made a breakthrough on an age-old limitation of the first law of thermodynamics. Paul Cassak, professor and associate director of the Center for KINETIC Plasma Physics, and graduate research assistant Hasan Barbhuiya, both in the Department of Physics and Astronomy, are studying how energy gets converted in superheated plasmas in space. Their findings, funded by a grant from the National Science Foundation and published in the Physical Review Letters journal, will revamp ...

Yeast used in production of cachaça can prevent asthma, study shows

Yeast used in production of cachaça can prevent asthma, study shows
2023-02-22
A daily dose of a strain of brewer’s yeast used to produce cachaça (distilled spirit made from fermented sugarcane juice) can act as a preventive against asthma, according to a Brazilian study involving male mice. The results are reported in an article published in the journal Probiotics and Antimicrobial Proteins. The authors are researchers at the University of São Paulo (USP) and the Federal University of Minas Gerais (UFMG). The yeast strain used in the study was Saccharomyces cerevisiae UFMG A-905. Asthma is a common lung condition that causes breathing difficulties. It ...

Out of the blue

2023-02-22
(Santa Barbara, Calif.) — Blue foods — those that come from the ocean or freshwater environments — have tremendous potential to help address several global challenges. With careful implementation of policies that leverage these foods, nations could get a boost on efforts to reduce nutritional deficits, lower disease risk, decrease greenhouse gas emissions and ensure resilience in the face of climate change. So say the team of experts at Blue Food Assessment, an international collaboration of scientists whose focus has been on the role of aquatic foods in global ...

Hands-free tech adds realistic sense of touch in extended reality

Hands-free tech adds realistic sense of touch in extended reality
2023-02-22
HOUSTON – (Feb. 22, 2023) – With an eye toward a not-so-distant future where some people spend most or all of their working hours in extended reality, researchers from Rice University, Baylor College of Medicine and Meta Reality Labs have found a hands-free way to deliver believable tactile experiences in virtual environments. Users in virtual reality (VR) have typically needed hand-held or hand-worn devices like haptic controllers or gloves to experience tactile sensations of touch. The new “multisensory pseudo-haptic” technology, which is described in an open-access ...

Physically demanding work tied to higher male fertility, study suggests

2023-02-22
A new study from researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that men who regularly lift heavy objects at work have higher sperm counts. The study, published in Human Reproduction, is part of the Environment and Reproductive Health (EARTH) cohort, a clinical study which aims to explore how exposure to environmental chemicals and lifestyle choices affect reproductive health. “We already know that exercise is associated with multiple health benefits in humans, including those observed on reproductive health, but few studies have looked at how occupational factors can ...

Aging | Metformin's impact on aging and longevity through DNA methylation

Aging | Metformins impact on aging and longevity through DNA methylation
2023-02-22
“In this study, we compared genome-wide DNA methylation rates among metformin users and nonusers [...]” BUFFALO, NY- February 22, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, “Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity.” Metformin, a commonly prescribed anti-diabetic medication, has repeatedly been shown to hinder aging in pre-clinical ...

As sea ice declines in the Arctic, bowhead whales are adjusting their migration patterns

As sea ice declines in the Arctic, bowhead whales are adjusting their migration patterns
2023-02-22
NEWPORT, Ore. – As sea ice declines in the Arctic, bowhead whales are staying north of the Bering Strait more frequently, a shift that could affect the long-term health of the bowhead population and impact the Indigenous communities that rely on the whales, a new study by Oregon State University researchers shows. Bowhead whales found in the Pacific Arctic, sometimes called Bering-Chukchi-Beaufort bowheads based on their migratory patterns, normally winter in the northern Bering Sea and migrate north in the spring through the Bering Strait to the Canadian Beaufort Sea, where they spend summer and fall. They then migrate ...

UBC's Daniel Pauly and Rashid Sumaila win Tyler Prize for Environmental Achievement

UBCs Daniel Pauly and Rashid Sumaila win Tyler Prize for Environmental Achievement
2023-02-22
Two courageous UBC ocean fisheries experts - marine biologist Dr. Daniel Pauly and fisheries economist Dr. Rashid Sumaila — have been awarded the 2023 Tyler Prize for Environmental Achievement. The award, administered by the University of Southern California, has often been described as the ‘Nobel Prize for the Environment.’ Both are University Killam Professors at the University of British Columbia, and long-time colleagues at its Institute for the Oceans and Fisheries. They said that winning this ...

MD Anderson Research Highlights for February 22, 2023

2023-02-22
HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a new understanding of how HPV drives cancer development, a combination therapy to overcome treatment resistance in mantle cell lymphoma, novel ...

Early Cretaceous shift in the global carbon cycle affected both land and sea

Early Cretaceous shift in the global carbon cycle affected both land and sea
2023-02-22
Scientists continue to refine techniques for understanding present-day changes in Earth’s environmental systems, but the planet’s distant past also offers crucial information to deepen that understanding. A geological study by University of Nebraska–Lincoln scientist Matt Joeckel and colleagues provides such information. Scientific research in recent decades has confirmed that major changes in the global carbon cycle caused significant changes in the Earth’s atmosphere and oceans 135 million years ago, during the early Cretaceous Period. A range of questions remain about the ...

Discovery of massive early galaxies defies prior understanding of the universe

Discovery of massive early galaxies defies prior understanding of the universe
2023-02-22
UNIVERSITY PARK, Pa. — Six massive galaxies discovered in the early universe are upending what scientists previously understood about the origins of galaxies in the universe.  “These objects are way more massive​ than anyone expected,” said Joel Leja, assistant professor of astronomy and astrophysics at Penn State, who modeled light from these galaxies. “We expected only to find tiny, young, baby galaxies at this point in time, but we’ve discovered galaxies as mature as our own in what was previously understood to be the dawn of the universe.” Using the first dataset released from NASA's James Webb Space Telescope, ...

Mechanisms underlying autoimmunity in Down syndrome revealed

Mechanisms underlying autoimmunity in Down syndrome revealed
2023-02-22
New York, NY (February 22, 2023) – Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature [DOI: https://doi.org/10.1038/s41586-023-05736-y]. The work adds to the research team’s findings published in the journal Immunity in October 2022, showing that people with Down syndrome have less frequent but more severe viral infections. Studying lab specimens from volunteers with Down syndrome, the investigators identified cytokines and a B cell subtype—key ...

Patients identified as frail before surgery less likely to die one year after

2023-02-22
PITTSBURGH, Feb. 22, 2023 – New research published today in JAMA Surgery shows that when frail patients are connected to resources, including conversations with a physician about possible outcomes and help preparing their body for surgery, they are less likely to die one year after surgery.   While age can be an important indicator of a patient’s likelihood of encountering adverse outcomes or complications of surgery, it does not provide a full picture of their health. Frailty considers the patient’s overall well-being, including their physical and cognitive abilities, as well as their body’s ability to recover from surgery.   “Frailty ...

Association of pandemic with unsafe living situations, intimate partner violence among pregnant individuals

2023-02-22
About The Study: This study found an overall increase in unstable and/or unsafe living situations and intimate partner violence (IPV) between January 2019 and December 2020, with a temporary increase associated with the COVID-19 pandemic. It may be useful for emergency response plans to include IPV safeguards for future pandemics. These findings suggest the need for prenatal screening for unsafe and/or unstable living situations and IPV coupled with referral to appropriate support services and preventive ...

Incidence of aggressive end-of-life care among older adults with metastatic cancer in nursing homes and community settings

2023-02-22
About The Study: The results of this study suggest that despite increased emphasis to reduce aggressive end-of-life care in the past several decades, such care remains common among older persons with metastatic cancer and is slightly more prevalent among nursing home residents than their community-dwelling counterparts. Multilevel interventions to decrease aggressive end-of-life care should target the main factors associated with its prevalence, including hospital admissions in the last 30 days of life and in-hospital death.   Authors: Siran M. Koroukian, Ph.D., of the Case Western Reserve University School of Medicine in Cleveland, is the corresponding ...

Rising river temperatures hold important clues about climate and other human impacts

2023-02-22
An improved global understanding of river temperature could provide an important barometer for climate change and other human activities. River temperature is the fundamental water quality measure that regulates physical, chemical and biological processes in flowing waters and, in turn, impacts ecosystems, human health, and industrial, domestic and recreational uses by people. In a comment piece in the new journal, Nature Water, researchers led by the University of Birmingham, UK, and Indiana University, USA, have called for an increased ...

Human body proven to predict mealtimes

2023-02-22
The human body can predict the timing of regular meals, according to a new study from the University of Surrey. The research team also found that daily blood glucose rhythms may be driven not only by meal timing but by meal size.   In the first study of its kind, researchers from Surrey, led by Professor Jonathan Johnston, investigated if the human circadian system anticipates large meals. Circadian rhythms/systems are physiological changes, including metabolic, that follow a 24-hour cycle and are usually synchronised to environmental signals, such as light and dark cycles.   Previous ...

James Webb spots super old, massive galaxies that shouldn’t exist

2023-02-22
In a new study, an international team of astrophysicists has discovered several mysterious objects hiding in images from the James Webb Space Telescope: six potential galaxies that emerged so early in the universe’s history and are so massive they should not be possible under current cosmological theory. Each of the candidate galaxies may have existed at the dawn of the universe roughly 500 to 700 million years after the Big Bang, or more than 13 billion years ago. They’re also gigantic, containing almost as many stars as the modern-day Milky Way Galaxy. “It’s ...

Climate ‘spiral’ threatens land carbon stores – study

2023-02-22
The world’s forests are losing their ability to absorb carbon due to increasingly ‘unstable’ conditions caused by humans, a landmark study has found. Dramatic changes to forests, and other habitats that store carbon in plants and soils, are becoming more likely in some regions across Earth, with less carbon consistently absorbed by the ‘land carbon sink’ provided by trees, soil and plants, according to scientists writing in Nature. The short-term impacts of rising temperatures, ...

Anti-dust tech paves way for self-cleaning surfaces

Anti-dust tech paves way for self-cleaning surfaces
2023-02-22
Dust is a common fact of life, and it's more than just a daily nuisance – it can get into machinery and equipment, causing loss of efficiency or breakdowns. Researchers at The University of Texas at Austin partnered with North Carolina-based company Smart Material Solutions Inc. to develop a new method to keep dust from sticking to surfaces. The result is the ability to make many types of materials dust resistant, from spacecraft to solar panels to household windows. The research is published in ACS Applied Materials & Interfaces. "What we've ...

Today’s pediatric heart transplantations involve sicker children, but have better outcomes

2023-02-22
Key takeaways Heart transplants offered to more patients with serious disease: A study of 323 pediatric heart transplants over 36 years at the University of Florida found that in recent years, more infants with serious congenital heart disease were offered heart transplants, but they had improved outcomes compared to patients in previous decades. Improved long-term survival: Despite extending the procedure to younger patients with more serious heart problems, 5-year survival improved from 70.7% in previous years to 83% in recent ...

Deep earthquakes could reveal secrets of the Earth’s mantle

2023-02-22
A new study from a University of Chicago scientist suggests there may be a layer of surprisingly fluid rock ringing the Earth, at the very bottom of the upper mantle. The finding was made by measuring the lingering movement registered by GPS sensors on islands in the wake of a deep earthquake in the Pacific Ocean near Fiji. Published Feb. 22 in Nature, the study demonstrates a new method to measure the fluidity of the Earth’s mantle. “Even though the mantle makes up the largest part of Earth, there’s ...

Study offers details on using electric fields to tune thermal properties of ferroelectric materials

2023-02-22
New research from North Carolina State University sheds light on how electric fields can be used to alter the thermal properties of ferroelectric materials, allowing engineers to manipulate the flow of heat through the materials. Ferroelectric materials are used in a wide variety of applications, from ultrasound devices to memory storage technologies. “Our work here is a significant advance because we worked with large sample sizes and provide detailed information on the relationship between the type of electric field being applied to the ferroelectric material and the thermal response in the material,” says Jun Liu, an associate professor of mechanical and aerospace ...

Second generation gene therapy for alpha 1-antitrypsin deficiency

Second generation gene therapy for alpha 1-antitrypsin deficiency
2023-02-22
Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in the peer-reviewed journal Human Gene Therapy. Click here to read the article now. In ATT deficiency, neutrophil proteases destroy the lung parenchyma, the portion of the lungs involved in gas exchange. The result is a high risk for the early onset of emphysema. Ronald Crystal, MD, from Weill Cornell Medicine, and coauthors, have developed an adeno-associated virus (AAV) serotype 8-based gene ...
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