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Mass General researchers find that targeting immune cells may help treat atrial fibrillation

2023-07-13
Key Takeaways Analyses of atrial heart tissue collected from patients with and without atrial fibrillation indicate that immune cells called macrophages expand more than any other cell type in diseased tissue. In a mouse model of atrial fibrillation, macrophages support inflammation and scarring of the atria, which hinder electrical conduction between heart cells. The SPP1 gene is highly overexpressed in macrophages during atrial fibrillation, and its expressed protein promotes tissue scarring. BOSTON – Current treatments for atrial fibrillation (AFib), a common heart condition characterized ...

The 10th World Congress on Targeting Microbiota 2023: Unveiling the Future of Microbiotal Medicine

The 10th World Congress on Targeting Microbiota 2023: Unveiling the Future of Microbiotal Medicine
2023-07-13
VENICE, ITALY - Set in the romantic city of Venice from October 17th to 19th, the 10th World Congress on Targeting Microbiota is set to convene. This worldwide gathering of researchers, clinicians, and industry professionals will offer a dynamic platform for in-depth discussions, latest research insights, and groundbreaking developments in the fascinating world of microbiota.   Targeting Microbiota 2023: What’s New? The congress will focus on breakthrough research and the latest developments in microbiotal medicine, exploring its implications ...

Synoptic reporting improves pretreatment CT for advanced ovarian cancer

Synoptic reporting improves pretreatment CT for advanced ovarian cancer
2023-07-13
Leesburg, VA, July 13, 2023—According to an accepted manuscript published in the American Journal of Roentgenology (AJR), a synoptic report improved completeness of pretreatment CT reports in patients with advanced ovarian cancer, including for established sites of unresectable or challenging-to-resect disease. “An ovarian cancer synoptic report increased completeness of reporting, facilitating referrer communication and having the potential to improve clinical decision-making,” wrote first ...

Purdue researchers receive $118,000 to develop freeze-drying, meat validation and thermal imaging innovations

Purdue researchers receive $118,000 to develop freeze-drying, meat validation and thermal imaging innovations
2023-07-13
WEST LAFAYETTE, Ind. – Purdue University researchers with patent-pending innovations for the agriculture, medical and autonomous transportation industries have received funding to further develop their work and bring it to the marketplace.  Researchers from the Bindley Bioscience Center and the College of Engineering have received more than $118,000 from the Trask Innovation Fund to make their work more attractive for commercial use. The fund is managed by the Purdue Research Foundation Office of Technology Commercialization. It awards up to $50,000 for short-term projects that enhance the commercial value of intellectual property. ...

Damon Runyon Cancer Research Foundation announces Fellowship stipend increase

2023-07-13
The Damon Runyon Cancer Research Foundation is pleased to announce that it will increase its Fellowship stipend by 15% over the award’s four-year term. Under the new terms, the Fellowship stipend will start at $70,000 and increase by $2,000 each year. Fellows will continue to receive an additional $2,000 each year for research-related expenses, for a total of $300,000 over the four years.  Damon Runyon programs are designed to address funding gaps and support today’s most promising young scientists as they launch careers in cancer research. The Foundation’s scientific advisers ...

A scalable, safer, and potentially cheaper way to isolate valuable isotopes

A scalable, safer, and potentially cheaper way to isolate valuable isotopes
2023-07-13
New York, NY—July 13, 2023—New research published in Science Advances, led by Yuan Yang, associate professor of materials science at Columbia Engineering, and collaborators at Lamont-Doherty Earth Observatory, demonstrates a novel technique for isolating isotopes.  High Stakes Oxygen is a critical component in the positron emission tomography (PET) scans oncologists use to search for tumors. But not just any oxygen will work. While most oxygen atoms have eight neutrons, about 1 in 500 atoms has ten. Those extra neutrons are necessary for the PET imaging scans to work. The Challenge It’s extremely expensive to isolate ...

Alien invasion: Study reveals alarming economic costs of biological invasions to the European Union

2023-07-13
Biological invasions are a major threat to ecosystems, biodiversity, and human well-being, resulting in ecosystem degradation and causing economic costs in the multi-trillions of euros globally. A study led by McGill University sheds light on the stark economic cost resulting from biological invasions in the European Union (EU). The European Union continues to be exposed to thousands of invasive alien species — harmful species introduced by humans from outside of their natural habitat. The EU is ...

Under representation of women in policing: Study reveals persistent barriers and gender differences in career advancement

2023-07-13
A new study published this week examines the under-representation of women in policing. It reveals that cultural and structural barriers persist and are impacting female career advancement when compared to that of male colleagues.   The research, carried out by the University of Portsmouth as part of Dr Jackie Alexander’s doctoral research, is based on unique survey and interview data with female and male senior police leaders in England and Wales. It highlights the challenges faced by women en route to a senior rank and the impact of gender differences ...

High-quality sleep promotes resilience to depression and anxiety

2023-07-13
Research has shown quality sleep can help bolster resilience to depression and anxiety. The study, led by researchers at the University of York, highlights that chronic stress is a major risk factor for a number of mental health disorders, including depression and pathological anxiety, but high-quality sleep and coping strategies - such as the ability to reframe a situation to see the positive side - can help to prevent poor mental health when faced with negative or stressful experiences. The research studied data from over 600 participants during the COVID-19 pandemic ...

Multicultural Psychology Consultation Team promotes culturally responsive care in hospital system

2023-07-13
July 13, 2023 — The synergistic epidemics of COVID-19, racial injustice, and health inequities have prompted patients and communities to press harder for culturally responsive health care. In Harvard Review of Psychiatry (HRP), published in the Lippincott portfolio by Wolters Kluwer, members of the originating Multicultural Psychology Consultation Team (MPCT) describe how they're delivering culturally responsive mental health treatment while promoting inclusive health care workplace environments. The ...

The MemTrax Continuous Recognition Test for advanced cognitive impairment screening

The MemTrax Continuous Recognition Test for advanced cognitive impairment screening
2023-07-13
“[...] MemTrax quickly demonstrates and quantifies the pertinent memory dysfunction of Alzheimer’s disease.” BUFFALO, NY- July 13, 2023 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, “Advancing screening for cognitive impairment: the memtrax continuous recognition test.” Extensive efforts to find a treatment for Alzheimer’s disease (AD) span over 40 years, with the often-repeated request ...

People with more empathy more likely to support international sharing of coronavirus vaccines, study shows

2023-07-13
People with more empathy and cosmopolitan beliefs are more likely to support the international sharing of coronavirus vaccines, a new study shows.  During the COVID-19 pandemic, many residents of high-income countries were eligible for COVID-19 vaccine boosters, while many residents of lower-income countries had not yet received a first dose.   Researchers analysed the levels and predictors of international vaccine solidarity through a survey of around 2,000 German adults in the autumn of 2021. They measured their ...

Central component of infection revealed in people living with HIV

Central component of infection revealed in people living with HIV
2023-07-13
Québec, July 13, 2023 – Professor Simona Stäger’s team has made a breakthrough in the study of the human immunodeficiency virus (HIV). The researchers have identified the mechanism by which memory CD4+ T lymphocytes—cells that play a major role in our immune response—are predisposed to cell death in people living with HIV. The team’s findings have just been published in JCI Insight.   In this new study, Professor Stäger and her research team built on work done on mice infected with the Leishmania donovani parasite (published in Cell Reports in 2018), which described how a chronic inflammatory environment predisposes ...

Controlled cruelty: New study from VCU finds aggression can arise from successful self-control

2023-07-13
RICHMOND, Va. (July 13, 2023) — A new study by a Virginia Commonwealth University researcher has found that aggression is not always the product of poor self-control but, instead, often can be the product of successful self-control in order to inflict greater retribution. The new paper, “Aggression As Successful Self-Control,” by corresponding author David Chester, Ph.D., an associate professor of social psychology in the Department of Psychology at VCU’s College of Humanities and Sciences, was published by the journal Social and Personality Psychology Compass and uses meta-analysis to summarize evidence from dozens of existing ...

Successful cooperation depends on good mindreading abilities - study

2023-07-13
A person’s ‘mindreading ability’ can predict how well they are able to cooperate, even with people they have never met before. Researchers at the University of Birmingham found that people with strong mind reading abilities – the ability to understand and take the perspective of another person’s feelings and intentions– are more successful in cooperating to complete tasks than people with weaker mind reading abilities.  These qualities, also called ‘theory of mind’, are not necessarily related to intelligence and could be improved through training programmes to foster improved cooperation, for example in ...

Low-dose atropine eyedrops no better than placebo for slowing myopia progression

Low-dose atropine eyedrops no better than placebo for slowing myopia progression
2023-07-13
Use of low-dose atropine eyedrops (concentration 0.01%) was no better than placebo at slowing myopia (nearsightedness) progression and elongation of the eye among children treated for two years, according to a randomized controlled trial conducted by the Pediatric Eye Disease Investigator Group (PEDIG) and funded by the National Eye Institute (NEI). The trial aimed to identify an effective way to manage this leading and increasingly common cause of refractive error, which can cause serious uncorrectable vision loss later in life. Results from the trial were published in JAMA Ophthalmology. Importantly, the findings contradict results from recent trials, primarily in East Asia, which ...

Low-dose atropine eye drops vs placebo for myopia control

2023-07-13
About The Study: In this randomized clinical trial of school-age children in the U.S. with low to moderate myopia (nearsightedness), atropine, 0.01%, eye drops administered nightly when compared with placebo did not slow myopia progression or axial elongation. These results do not support use of atropine, 0.01%, eye drops to slow myopia progression or axial elongation in U.S. children. Authors: Michael X. Repka, M.D., M.B.A., of the Wilmer Eye Institute in Baltimore, is the corresponding author. To access the embargoed study: Visit our For The Media website at this ...

COVID-19 severity and waning immunity after up to 4 mRNA vaccine doses in patients with cancer

2023-07-13
About The Study: This study provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in patients with cancer. Longevity of immunity in preventing severe COVID-19 outcomes in actively treated patients with cancer, cancer survivors, and matched controls was observed at least five months after the third or fourth dose.  Authors: Raghav Sundar, M.B.B.S., Ph.D., of the National University Health System in Singapore, and Kelvin Bryan Tan, Ph.D., of the Ministry of Health in Singapore, are the corresponding authors.  To access the embargoed study: Visit our ...

Objectively measured visual impairment and dementia prevalence in older adults

2023-07-13
About The Study: In this survey study, all types of objectively measured visual impairment were associated with a higher dementia prevalence. As most visual impairment is preventable, prioritizing vision health may be important for optimizing cognitive function. Authors: Joshua R. Ehrlich, M.D., M.P.H., of the University of Michigan in Ann Arbor, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamaophthalmol.2023.2854) Editor’s Note: Please see the article for ...

How COVID-19 crosses the placenta - study using placental tissue grown in the lab

How COVID-19 crosses the placenta - study using placental tissue grown in the lab
2023-07-13
RESEARCH REVEALS HOW COVID-19 VIRUS INFECTS THE PLACENTA, AND HOW THIS CAN BE PREVENTED In a landmark study published in Nature Cell Biology, Australian researchers, led by Professor Jose Polo from Monash University and the University of Adelaide and University of Melbourne’s Professor Kanta Subbarao from the Peter Doherty Institute for Infection and Immunity (Doherty Institute), have revealed how COVID-19 can infect the human placenta. Research has shown that COVID-19 infections during pregnancy ...

The timekeeper within: New discovery on how the brain judges time

The timekeeper within: New discovery on how the brain judges time
2023-07-13
From Aristotle’s musings on the nature of time to Einstein’s theory of relativity, humanity has long pondered: how do we perceive and understand time? The theory of relativity posits that time can stretch and contract, a phenomenon known as time dilation. Just as the cosmos warps time, our neural circuits can stretch and compress our subjective experience of time. As Einstein famously quipped, “Put your hand on a hot stove for a minute, and it seems like an hour. Sit with a pretty girl for an hour, and it seems like a minute”. In new work ...

Tau-based biomarker tracks Alzheimer’s progression

Tau-based biomarker tracks Alzheimer’s progression
2023-07-13
Two pathologies drive the progression of Alzheimer’s disease. Early on, amyloid beta plaques lead the way, but around the time cognitive symptoms arise, tau tangles take over as the driving force and cognition steadily declines. Tracking the course of the disease in individual patients has been challenging because there’s been no easy way to measure tau tangles in the brain. But now, researchers at Washington University School of Medicine in St. Louis and Lund University in Lund, Sweden, have identified a form of tau that could serve as a marker to track Alzheimer’s progression. The marker also could be used by Alzheimer’s drug developers to assess ...

Engineering dual carriageways for signals

2023-07-13
Routing signals and isolating them against noise and back-reflections are essential in many practical situations in classical communication as well as in quantum processing. In a theory-experimental collaboration, a team led by Andreas Nunnenkamp from the University of Vienna and Ewold Verhagen based at the research institute AMOLF in Amsterdam has achieved unidirectional transport of signals in pairs of "one-way streets". This research published in Nature Physics opens up new possibilities for more flexible signaling devices. Devices that allow ...

In historic procedure, donor liver protects heart transplant

In historic procedure, donor liver protects heart transplant
2023-07-13
Doctors in Seattle are reporting a history-making case in which a patient received two donor organs, a liver and a heart, to prevent the extreme likelihood that her body would reject a donor heart transplanted alone. In this innovative case, the organ recipient’s own healthy liver was transplanted, domino-like, into a second patient who had advanced liver disease. The dual-organ recipient, Adriana Rodriguez, 31, of Bellingham, Washington, has recovered well since the Jan. 14, 2023, procedures, said Dr. Shin Lin, a cardiologist ...

Red pill or blue pill? The critical decision to control the superbugs

2023-07-13
Researchers from Tokyo Medical and Dental University (TMDU) investigate a pharmacist-led intervention to optimize the oral antimicrobial prescriptions in dental setting Tokyo, Japan - The battle to stop the increase of superbugs in hospitals has been an ongoing struggle for healthcare professionals. Dentists are currently facing a medical challenge that determines the faith of antimicrobial resistance in healthcare settings. To choose the “red pill” means to embrace the painful truth that bacteria are acquiring resistance to many antimicrobials. Meanwhile, the “blue pill” creates ...
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