Terasaki Institute scientist awarded 2024 NARSAD Young Investigator Grant
2024-08-29
LOS ANGELES, August 29, 2024 — Yangzhi Zhu, Ph.D., Assistant Professor at the Terasaki Institute for Biomedical Innovation (TIBI), has been awarded the prestigious 2024 NARSAD Young Investigator Grant for his groundbreaking work on a lab-on-a-contact lens (LoCL) system. This innovative technology is designed to monitor mental health by providing real-time, non-invasive tracking of panels of key biomarkers, from the wearer’s tears.
Mental health disorders, such as anxiety and depression, affect nearly a billion ...
A breakthrough in diagnosing hydrocephalus: Multimodality approaches enhance accuracy and reduce costs
2024-08-29
A recent case report published in Cyborg Bionic Systems details the diagnosis of Idiopathic Normal Pressure Hydrocephalus (iNPH) using multimodality diagnostic approaches, highlighting significant advancements in medical diagnostics and patient care. The study conducted by a team of researchers from Tianjin Medical University General Hospital, Tianjin, China, presents a comprehensive case study of a 68-year-old male patient diagnosed with iNPH, showcasing the effectiveness of these advanced diagnostic techniques.
iNPH is a condition characterized by the accumulation of cerebrospinal fluid (CSF) causing ventricular dilation, ...
This tiny backyard bug does the fastest backflips on earth
2024-08-29
Move over, Sonic. There’s a new spin-jumping champion in town – the globular springtail (Dicyrtomina minuta). This diminutive hexapod backflips into the air, spinning to over 60 times its body height in the blink of an eye, and a new study features the first in-depth look at its jumping prowess.
Globular springtails are tiny, usually only a couple millimeters in body length. They don’t fly, bite or sting. But they can jump. In fact, jumping is their go-to (and only) plan for avoiding predators. And they excel at it – to the naked eye it seems as though they vanish entirely when they take off.
“When globular springtails ...
Climate change increases foodborne illness risk from raw produce
2024-08-29
Highlights:
Salmonella enterica causes disease in 1.2 million people in the U.S. annually.
The most common way people get infected is by consuming contaminated fresh produce.
New research shows that bacterial leaf spot of lettuce and high humidity promote S. enterica growth in lettuce, and climate change is predicted to increase humid periods.
Washington, D.C.—Climate change will increase the risk of the foodborne illness from Salmonella enterica, according to a new study. The research was published today in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
S. enterica causes disease in 1.2 million people in the ...
NSF Grant empowers FAU to explore Caribbean climate crisis with ethnography
2024-08-29
Transformations in the global climate system are profoundly destabilizing ecosystems across the Caribbean, with South Florida and Puerto Rico experiencing notable impacts. To address this challenge, researchers from Florida Atlantic University and the University of Puerto Rico (UPR) in Cayey, are turning to ethnography – an in-depth, immersive research method that involves observing and interviewing people in their natural settings.
FAU’s Dorothy F. Schmidt College of Arts and Letters, in collaboration with UPR Cayey, has received a $650,000 grant from ...
A bacterial defense with potential application in genome editing
2024-08-29
COLUMBUS, Ohio – Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.
The system involves two proteins that team up to disable plasmids, small DNA molecules that exchange genetic information among different bacterial strains. While plasmids provide evolutionary benefits, they can also be seen by host bacteria as threats.
The research team determined that one protein uses a short piece of DNA – known as a DNA guide – to ...
Labor day crowds temporarily impact local streams, research shows
2024-08-29
Crowds flocking to rivers and streams over Labor Day weekend are doing more than cooling off and having fun. They’re temporarily introducing chemicals and microscopic organisms into their local waterways, according to new research from Johns Hopkins University.
The research, published today in ACS ES&T Water, is the first holistic assessment of how recreation impacts streams. Findings also provide insight into the compounds and chemicals people are splashing around in when their favorite swimming spots are packed.
“Residue from ...
Borderzone Breakthrough: A new source of cardiac inflammation
2024-08-29
Ischemic heart disease is the most common cause of death in the world. It begins with a “heart attack”, also known as a myocardial infarction (MI), which causes part of the heart to die due to inadequate coronary blood flow. This leads to vigorous inflammation, heart wall remodeling, and heart failure.
Anti-inflammatory drugs have been surprisingly ineffective at preventing heart failure. As a consequence, they are not a routine part of post-MI care. However, it is possible that the most potent molecular and cellular inflammation targets have yet to be discovered.
In the Aug. 28, ...
New study assesses the efficacy of suvorexant in reducing delirium in older adults
2024-08-29
Delirium is a sudden onset and temporary state of disturbed consciousness or cognition, occurring due to underlying medical issues like fever or alcohol withdrawal. It is most common among older hospitalized adults aged 75 years or above, leading to increased risk of falls, dementia, low life expectancy, and high healthcare expenses.
Non-pharmacological approaches to prevent or reduce delirium are time-consuming, hard to implement, and partially effective. So, pharmacological interventions offer hope. Insomnia, a significant risk factor for delirium, could be alleviated with sleep-promoting medications. However, not all ...
Gene therapy gets a turbo boost from University of Hawaii researchers
2024-08-29
For decades, scientists have dreamt of a future where genetic diseases, such as the blood clotting disorder hemophilia, could be a thing of the past. Gene therapy, the idea of fixing faulty genes with healthy ones, has held immense promise. But a major hurdle has been finding a safe and efficient way to deliver those genes.
Now, researchers at the University of Hawaiʻi’s John A. Burns School of Medicine (JABSOM) have made a significant breakthrough in gene editing technology that could revolutionize how we treat genetic diseases. Their new method offers a faster, safer, and more efficient way to deliver healthy ...
Global timber supply threatened as climate change pushes cropland northwards
2024-08-29
Climate change will move and reduce the land suitable for growing food and timber, putting the production of these two vital resources into direct competition, a new study has found.
The sight of vineyards in Britain is becoming more common as hotter summers create increasingly suitable conditions for growing grapes. But behind this success story is a sobering one: climate change is shifting the regions of the world suitable for growing crops.
Researchers at the University of Cambridge have uncovered a looming issue: as the ...
Researchers identify basic approaches for how people recognize words
2024-08-29
University of Iowa researchers have defined how people recognize words.
In a new study with people who use cochlear implants to hear, the researchers identified three main approaches that people with or without hearing impairment use to recognize words, an essential building block for understanding spoken language. Which approach depends on the person, regardless of hearing aptitude or ability: Some wait a bit before identifying a word, while others may tussle between two or more words before deciding which word has been heard.
When a person hears a word, the brain briefly considers hundreds, if not thousands, ...
Experts call for routine measurement of lipoprotein (a) levels
2024-08-29
London, UK: Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.
The findings come from several studies presented at the European Society of Cardiology (ESC) Congress taking place in London, UK, this week [1] and published in two journals: Progress in Cardiovascular Disease and Archives of Medical Sciences [2].
LP(a) is a parcel of fats (also known ...
Land-sea “tag-team” devastated ocean life millions of years ago reveal scientists
2024-08-29
Scientists have revealed how a “tag-team” between the oceans and continents millions of years ago devastated marine life – and altered the course of evolution on Earth.
Their study has unearthed a new explanation for a string of severe environmental crises, called oceanic anoxic events, which happened between 185 and 85 million years ago.
These occurred when the seas became critically depleted of dissolved oxygen.
Experts from the University of Southampton, which led the study, said these events triggered significant biological upheavals, including ...
Researchers map 50,000 of DNA’s mysterious ‘knots’ in the human genome
2024-08-29
Researchers map 50,000 of DNA’s mysterious ‘knots’ in the human genome
Innovative study of DNA’s hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.
DNA is well-known for its double helix shape. But the human genome also contains more than 50,000 unusual ‘knot’-like DNA structures called i-motifs, researchers at the Garvan Institute of Medical Research have discovered.
Published today in The EMBO Journal is the first comprehensive map of these unique DNA structures, shedding light on their potential roles in gene regulation involved in disease.
In a landmark 2018 study, Garvan scientists ...
Can fungi turn food waste into the next culinary sensation?
2024-08-29
Chef-turned-chemist Vayu Hill-Maini has a passion: to turn food waste into culinary treats using fungi.
One of his collaborators is Rasmus Munk, head chef and co-owner of the Michelin two-star restaurant Alchemist in Copenhagen, who serves a dessert — orange-colored Neurospora mold grown on rice — inspired by Hill-Maini.
For the past two years, Hill-Maini has worked with a team of chefs at Blue Hill at Stone Barns, a Michelin two-star restaurant in Pocantico Hills, New York, to generate tasty morsels from Neurospora mold grown on grains and pulses, including the pulp left over from making oat ...
Women with endometriosis at greater associated risk of heart attack and stroke
2024-08-29
London, United Kingdom – 29 Aug 2024: According to research presented at ESC Congress 2024,1 women with endometriosis have a 20% greater risk of significant cardiac outcomes compared with women without endometriosis.
“For decades, cardiovascular disease (CVD) has been thought of as a man’s disease and risk factors have been considered from the male perspective, for example, including erectile dysfunction in guidelines on CVD risk assessment.2 Yet, 1 in 3 women die from CVD and 1 in 10 women suffer from ...
Catching up on sleep on weekends may lower heart disease risk by up to 20%
2024-08-29
London, United Kingdom – 29 August 2024: The demands of the working week, often influenced by school or work schedules, can lead to sleep disruption and deprivation. However, new research presented at ESC Congress 2024 shows that people that ‘catch up’ on their sleep by sleeping in at weekends may see their risk of heart disease fall by one-fifth.
“Sufficient compensatory sleep is linked to a lower risk of heart disease,” said study co-author Mr Yanjun Song of the State Key Laboratory ...
Quitting smoking nearly halves heart attack risk, cutting down does little
2024-08-29
London, United Kingdom – 29 August 2024: According to research presented today at ESC Congress 2024,1 patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a major event by almost 50%. In contrast, there was minimal impact on cardiovascular risk in patients who reduced their smoking habits.
The international CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY ...
Children contribute to group projects when there are clear and common goals
2024-08-29
Children can work together to reach a target that benefits a whole group even if it is at a personal cost to themselves, a new study has shown.
Researchers invited groups of six to 10-year-olds to take part in a game where they were each given containers of water and could decide how much of it to offer into a common pool.
If the group contributed a certain amount of water it resulted in benefits for the whole group, but children also obtained benefits for any water they kept.
At the same time, the ...
Dine on DNA: Compounds from nucleic acids in food show anticancer effects
2024-08-29
When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor Akiko Kojima-Yuasa of the Graduate School of Human Life and Ecology and colleagues.
Consuming nucleic acids found in food has been shown to boost the immune system and prevent some diseases. The nucleotides and nucleosides that result from digesting the acids are largely responsible for these beneficial effects.
Professor ...
MCG scientists working to understand why men with prostate cancer are at higher risk of Alzheimer’s
2024-08-29
AUGUSTA, Ga. (Aug. 29, 2024) – Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer’s disease, and whether it’s the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.
The hormone therapy, androgen deprivation therapy, known as ADT, treats the cancer by reducing testosterone, which the cancer needs to grow. But androgen is a key regulator of amyloid metabolism and when it’s removed from the equation, more amyloid is left to form the plaques that are a hallmark of Alzheimer’s.
“We ...
Ancient sea cow attacked by a crocodile and sharks sheds new light on prehistoric food chains
2024-08-29
A new study describing how a prehistoric sea cow was preyed upon by not one, but two different carnivores – a crocodilian and a shark – is revealing clues into both the predation patterns of ancient creatures and the wider food chain millions of years ago.
Published in the peer-reviewed Journal of Vertebrate Paleontology, the findings mark one of the few examples of a creature being preyed upon by different animals during the Early to Middle Miocene epoch (23 million to 11.6 million years ago).
Predation marks in the skull indicate that the dugongine sea cow, ...
Georgia Tech neuroscientists explore the intersection of music and memory
2024-08-29
By Jerry Grillo
The soundtrack of this story begins with a vaguely recognizable and pleasant groove. But if I stop writing and just listen for a second, the music reveals itself completely. In Freddie Hubbard’s comfortable, lilting trumpet solo over Herbie Hancock’s melodic, repetitive piano vamping, I recognize “Cantaloupe Island.” Then, with my fingers again poised at the keyboard, Freddie and Herbie fade into the background, followed by other instrumental music: captivating — but not distracting — sonic nutrition, feeding my concentration and productivity.
Somewhere, I think, Yiren Ren is studying, focused on her ...
Waging war on ‘superbugs’ in aged care
2024-08-29
There’s an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic resistant bacteria or ‘superbugs’, researchers from Flinders University and SAHMRI warn.
A new study published in the well-respected Journal of Infection, explores the link between the widespread use of antibiotics in residential aged care and the resulting antibiotic resistant bacteria in the gut that can be passed on to other residents.
“Commonly ...
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