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Using AI to find persuasive public health messages and automate real-time campaigns

2025-06-17
AI can help public health agencies in the quest to end HIV. The United States is pursuing an initiative to end the HIV epidemic by 2030. To achieve this goal, public health agencies and organizations must remind the public about how best to avoid transmitting and acquiring the virus. Public health campaigns are costly, their effectiveness is seldom systematically assessed, and no systematic methods have been developed to build health campaigns in real-time. Dolores Albarracin and colleagues collected public health messages about HIV prevention and testing from US federal agencies, non-profit organizations, ...

Gene therapy for glaucoma

2025-06-17
Gene editing could be used to treat millions of glaucoma patients. Glaucoma is a leading cause of blindness, characterized by high pressure inside the eye. Patients often rely on daily eye drops to lower intraocular pressure, but the drops may cause significant complications including bradycardia, metabolic acidosis, and kidney stones. In addition, many patients fail to keep up with the eye drops. Yang Sun and colleagues used the CRISPR gene editing technique to knock down two genes associated with the production ...

Teaching robots to build without blueprints

2025-06-17
Bees, ants and termites don’t need blueprints. They may have queens, but none of these species breed architects or construction managers. Each insect worker, or drone, simply responds to cues like warmth or the presence or absence of building material. Unlike human manufacturing, the grand design emerges simply from the collective action of the drones — no central planning required. Now, researchers at Penn Engineering have developed mathematical rules that allow virtual swarms of tiny robots to do the same. In computer simulations, the robots built honeycomb-like structures without ever following — or even being able to comprehend — ...

Negative perception of scientists working on AI

2025-06-17
A public survey indicates that Americans have negative opinions of scientists who work on AI. Dror Walter and colleagues collected opinions about scientists from thousands of US adults via the Annenberg Science and Public Health survey and compared the perceived credibility, prudence, unbiasedness, self-correction, and benefit of scientists working on AI with those of scientists in general and climate scientists in particular. Previous work has established that high scores on these dimensions predict support for science ...

How disrupted daily rhythms can affect adolescent brain development

2025-06-17
A new McGill University-led study suggests that disrupting the body’s internal clock during adolescence can alter how the brain responds to an in-utero risk factor linked to certain brain disorders. Previous research has shown that a mother’s infection during pregnancy, such as the flu, can increase a child’s risk of developing conditions like schizophrenia and autism spectrum disorders later in life. Irregular sleep patterns – often a sign of circadian rhythm disruption – are also associated with these conditions. To investigate how these factors interact, researchers exposed mice to either a ...

New use for old drug: study finds potential of heart drug for treating growth disorders

2025-06-17
Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix (ECM) in the bone growth plates. A peptide hormone, known as C-type natriuretic peptide (CNP), plays a pivotal role by binding to its specific receptors present on the chondrocytes and triggering a signaling cascade in these cells. The CNP-bound receptor activates a molecule, cyclic guanosine monophosphate (cGMP), which in turn activates ...

Head-to-head study shows bariatric surgery superior to GLP-1 drugs for weight loss

2025-06-17
WASHINGTON, DC – June 17, 2025 – Sleeve gastrectomy and gastric bypass were associated with about five-times more weight loss than weekly injections of GLP-1 receptor agonists semaglutide or tirzepatide,* at the end of two years, according to a new head-to-head real-world study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting. Researchers from NYU Langone Health and NYC Health + Hospitals discovered patients who had one of the bariatric procedures lost an average 58 pounds after two years compared to 12 pounds ...

Psychiatric disorders less likely after weight-loss surgery than treatment with GLP-1s

2025-06-17
WASHINGTON, DC – June 17, 2025 – People who have metabolic and bariatric surgery are significantly less likely to develop psychiatric disorders compared to those who take weekly injections of GLP-1 anti-obesity medications, according to a new study* presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting. Over a five-year period, the risk of developing cognitive deficits was 54% lower and 18% and 17% lower for anxiety disorders and substance use ...

The higher the body mass index, the higher the risk for complications after bariatric surgery

2025-06-17
WASHINGTON, DC – June 17, 2025 – The higher a person’s body mass index (BMI), the higher their risk for complications after bariatric surgery, especially those with BMI of 50 or more, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting. Researchers found that the rate of complications increased by an average of 5.56% and serious occurrences rose 3.21% from the lowest BMI category to the highest, with people with a BMI 50 or more the most likely to experience complications of any kind.   The study gives new insights into the risks associated ...

Black patients have higher rate of minor complications after metabolic and bariatric surgery than white patients

2025-06-17
WASHINGTON, DC – June 17, 2025 – Black patients are more likely to experience minor complications after metabolic and bariatric surgery than White patients, according to new study* presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting. Researchers from the Yale School of Medicine found Black patients had a higher overall incidence of minor complications such as dehydration, trips to the emergency department (ED) and infections in ...

A revolution for R&D with the missing link of machine learning — project envisions human-AI expert teams to solve grand challenges

2025-06-17
The founding director of the institute, Aalto University professor Samuel Kaski has received the European Research Council Advanced Grant to develop new types of machine learning. Many popular and widely available AI tools appear to be extremely versatile and agile, but there is still a hole in the underlying machine learning, argues Kaski. "The basic tenet of machine learning is to apply a model trained on a learning data set. But that only works if the set is representative of the deployment setting — and that seldom holds, because life happens. Unexpected factors, statistically speaking covariates ...

4 ERC Advanced Grants: 10 million Euro for ISTA

2025-06-17
The Institute of Science and Technology Austria (ISTA) in Klosterneuburg receives over 10 million Euro by the European Research Council (ERC). Four research projects – in astrophysics, neuroscience, brain imaging, and math – were awarded around 2.5 million Euro each in the form of a competitive ERC Advanced Grant. ISTA is one of the most successful institutions at winning grants from this EU funding body. The European Research Council awards Advanced Grants to “active researchers who have a track-record of significant research achievements.” They are awarded for a period of up to 5 years and for up to 2.5 ...

ERC awards €2.5 million to TIGEM scientist for project on programmable genetic circuits

2025-06-17
The future of gene therapy is arriving in the form of intelligent genetic circuits. Diego di Bernardo, Genomic Medicine Program Coordinator at the Telethon Institute of Genetics and Medicine (TIGEM) and Professor of Biomedical Engineering at the University of Naples “Federico II,” has been awarded a prestigious €2.5 million ERC Advanced Grant for DIMERCIRCUITS — a project that merges synthetic biology, artificial intelligence, and biomedical engineering to transform how we ...

Tree rings reveal increasing rainfall seasonality in the Amazon

2025-06-17
Scientists have used clues locked into tree rings to reveal major changes in the Amazon’s rainfall cycle over the last 40 years:  wet seasons are getting wetter and dry seasons drier. Oxygen isotope signals in rings from two Amazon tree species allowed the international research team to reconstruct seasonal changes in rainfall for the recent past. Publishing their findings today (17 June) in Communications Earth and Environment, the researchers reveal that wet season rainfall has increased by 15 - 22%, and dry season rainfall decreased by 5.8 - 13.5% since 1980. The study is a result of a collaboration ...

Scientists find unexpected deep roots in plants

2025-06-17
Plants and trees extend their roots into the earth in order to draw nutrients and water from the soil—however, these roots are thought to decline as they move deeper underground. But a new study by a multi-institutional team of scientists shows that many plants develop a second, deeper layer of roots—often more than three feet underground—to access additional nourishment.  Published in the journal Nature Communications, the study reveals previously unrecognized rooting patterns, altering our understanding of how ecosystems respond to changing environmental conditions. More importantly, the study suggests that plants might transport and store fixed carbon deeper than ...

Researchers unveil the immune cells responsible for systemic sclerosis’s deadliest complications

2025-06-17
Osaka, Japan – Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients with the same disease exhibit different symptoms. Now, researchers from Japan have reported a cellular signature that might explain why some patients with autoimmune disease are stable while others face life-threatening complications. In a study to be published in Nature Communications, a multi-institutional research team led by The University of Osaka has revealed that, for patients with systemic sclerosis, this variation in disease severity seems to be due to the proliferation ...

New blood test holds potential to reduce liver transplant failures

2025-06-17
WASHINGTON -- Liver transplant is a lifesaving surgery, but a significant number of patients experience organ rejection or other complications. Now a new study by scientists from Georgetown University and MedStar Health describes how a single blood sample can be used to catch problems at the earliest stages, allowing tailored treatment to prevent the organ’s failure. The research, funded in part by the National Institutes of Health, is a major step toward the development of a liquid biopsy that could not only quickly detect post-transplant complications but also ...

Science clears the way to treating the trickiest bladder cancers

2025-06-17
Bladder tumors that have been excluded from clinical trials have a few things in common that could lead to new therapies.  Scientists at UC San Francisco have found a way to identify and possibly treat a mysterious type of bladder cancer that affects up to 1 in 4 cases.  First, they found a marker on the surface of the tumor cells that until now had only been associated with ovarian cancer; then they designed CAR-T therapy to kill the tumors in mice.  The discovery, which was made possible through funding from the National Institutes of Health (NIH), appears ...

Drug treatment alters performance in a neural microphysiological system of information processing

2025-06-17
In a world-first breakthrough, researchers have used an epilepsy-like disease model in a laboratory dish and showed that improved information processing and neural function can be achieved using a medication designed specifically to treat the disease. Published in Communications Biology, the research was led by Cortical Labs and marks a significant breakthrough in the study and treatment of neurological disorders in real time.      Cortical Labs is an Australian start-up which created the world’s first commercial biological computer, the CL1, which fuses lab-cultivated neurons from human stem cells with hard silicon to create ...

Wildfires could be harming our oceans and disrupting their carbon storage

2025-06-17
Wildfires pollute waterways and could affect their ability to sequester carbon, recent University of British Columbia research shows. Dr. Brian Hunt, professor in the Institute for the Oceans and Fisheries (IOF), and Emily Brown, IOF research scientist, discuss how wildfires affect our waters and what this means in a changing climate. What did you find about how fire affects water? BH: We focused on the mighty Fraser River basin. When forests burn, they release ash, soil particles and chemicals into the environment. In a recent study which analyzed water quality and wildfire data, we were able to link increases in the concentrations of compounds like arsenic and lead, as well as nutrients ...

Tarantulas bend rules to keep running after losing two legs

2025-06-17
It might be hard to imagine, but dropping a limb or two is routine for spiders. If moulting goes wrong or a leg gets stuck, the pragmatic arachnids simply detach the limb just beyond the body joint. Then it regrows within a month when they are young. But how do impaired spiders cope when suddenly relieved of a couple of limbs? Capturing dinner and evading predators could become an issue. However, going down from eight to six legs might not be a problem if spiders are adaptable. Maybe they relearn how to manoeuvre on just ...

How chemical bonds are formed: physicists at TU Graz observe energy flow in real time

2025-06-17
For the first time, a research team led by Markus Koch from the Institute of Experimental Physics at Graz University of Technology (TU Graz) has tracked in real time how individual atoms combine to form a cluster and which processes are involved. To achieve this, the researchers first isolated magnesium atoms using superfluid helium and then used a laser pulse to trigger the formation process. The researchers were able to observe this cluster formation and the involved energy transfer between individual atoms with a temporal ...

Fatty liver – but not liver damage – common in type 2 diabetes

2025-06-17
Six out of ten people with type 2 diabetes had fatty liver in a new study from Linköping University. Of these, only a small percentage had developed more severe liver disease. The study, published in the Journal of Internal Medicine, also helps confirm that those who have type 2 diabetes in combination with obesity are at greater risk of fatty liver leading to more severe liver disease. When metabolism does not work normally, as with so-called metabolic syndrome, many organs in the body are affected. “Metabolic syndrome is a combination of factors leading to the body accumulating fat and not managing blood sugar levels in a good way. This entails an increased risk of developing ...

Hydrogen sourcing could make or break Romania’s green steel ambitions, study finds

2025-06-17
A new study from the Stockholm School of Economics finds that the competitiveness of green steel production in Romania partly hinges on hydrogen sourcing—requiring a 15 percent price premium if hydrogen is purchased externally as supposed to produced on-site. Without this premium, decarbonizing the country’s only primary steel producer could result in billions of losses. The research, published in the Journal of Industrial Ecology, evaluates the financial viability of Liberty Steel Galați’s transition to low-carbon steelmaking using green hydrogen and electric arc furnace-based technologies. The plant, one of the EU’s top 10 most polluting steel facilities, aims ...

Disconnected from math, students call for real-world relevance in RAND’s first-ever youth survey

2025-06-17
According to the first-ever survey fielded to RAND’s new American Youth Panel (AYP), 49% of students in middle and high school grades reported losing interest in math about half or more of the time, and 75% of youths reported losing interest for at least some class time.   Loss of interest in math is consistent across genders and racial and ethnic groups.   In the fall of 2024, RAND asked youths in grades 5 through 12 about their math class experiences with plans to measure these math attitudes annually to track trends over time. This nationally representative report was fielded to a group of ...
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