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How hope beats mindfulness when times are tough

2024-08-30
A recent study finds that hope appears to be more beneficial than mindfulness at helping people manage stress and stay professionally engaged during periods of prolonged stress at work. The study underscores the importance of looking ahead, rather than living “in the moment,” during hard times. Mindfulness refers to the ability of an individual to focus attention on the present, in a way that is open, curious and not judgmental. Essentially, the ability to be fully in the moment. “There’s a lot of discussion ...

NASA, ESA missions help scientists uncover how solar wind gets energy

NASA, ESA missions help scientists uncover how solar wind gets energy
2024-08-30
Since the 1960s, astronomers have wondered how the Sun’s supersonic “solar wind,” a stream of energetic particles that flows out into the solar system, continues to receive energy once it leaves the Sun. Now, thanks to a lucky lineup of a NASA and an ESA (European Space Agency)/NASA spacecraft both currently studying the Sun, they may have discovered the answer — knowledge that is a crucial piece of the puzzle to help scientists better forecast solar activity between the Sun and Earth. A paper published in the Aug. 30, 2024, issue of the journal Science provides persuasive ...

Biodiversity loss: Many students of environment-related subjects are partly unaware of the causes

Biodiversity loss: Many students of environment-related subjects are partly unaware of the causes
2024-08-30
Worldwide survey by Goethe University FrankfurtFRANKFURT. Of the estimated 10 million, mostly still undiscovered species of flora and fauna on Earth, one million could become extinct in the next decades. This loss of biodiversity would have dramatic consequences, as animals and plants are providers of multiple services: They maintain ecosystems, ensure a more balanced climate on our planet, and supply us with food and active substances for medical drugs. Put bluntly: Without biodiversity, we humans will not survive. That is why there is an urgent need for resolute political measures to counter the “sixth mass extinction” in Earth’s history. One group of people who are particularly ...

UTHealth Houston and Baylor College of Medicine collaborate on first CDC Injury Control Research Center in Southwest, established to study injury and violence prevention

2024-08-30
The only Injury Control Research Center in Texas has been established by the Centers for Disease Control and Prevention at UTHealth Houston in partnership with Baylor College of Medicine.  “I’m beyond thrilled to bring an Injury Control Research Center to Texas,” said Jeff Temple, PhD, director of the new center and associate dean for clinical research at UTHealth Houston School of Behavioral Health Sciences. “This collaboration between the community, policymakers, UTHealth Houston, and Baylor College of Medicine will undoubtedly save lives.”  An Injury Control Research ...

New findings on TB could change how we treat inflammatory disorders

2024-08-30
Tuberculosis is a confounding scourge. It’s the leading cause of death from infectious disease in the world, and yet it’s estimated that those deaths represent perhaps 5% of infections with Mycobacterium tuberculosis (Mtb). Antibiotics can take credit for saving the lives of some of those with Mtb, but a chasm nevertheless persists between the prevalence of infection and the targeted severity of its impact. A growing body of evidence suggests genetic vulnerabilities to TB account for that gap. Now researchers from ...

Research Spotlight: A blood-based assay for the detection of IDH1.R132H-mutant gliomas

2024-08-30
Leonora Balaj, PhD, an investigator in the department of Neurosurgery at Massachusetts General Hospital and an assistant professor of Neurosurgery at Harvard Medical School, is co-senior author of a new paper in Nature Communications, Clinical Utility of a Blood Based Assay for the Detection of IDH1.R132H-Mutant Gliomas. Bob Carter, MD, chair of Neurosurgery at Mass General, is co-senior author of the study. Syeda Maheen Batool, MD, an instructor in investigation in Neurosurgery at Mass General, is lead author. Background: Glioma represents the most common central nervous system cancer in adults. The current ...

Genomic dark matter solves butterfly evolutionary riddle

Genomic dark matter solves butterfly evolutionary riddle
2024-08-30
[Note: High-resolution images related to this research available for download at this link. Caption and credit information provided.]   WASHINGTON (August 30, 2024) — A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. In a study published in the Proceedings of the National Academy of Sciences, the team, led by Luca Livraghi at the George Washington University and the University of Cambridge, discovered ...

Like people, vultures get set in their ways and have fewer friends as they age

2024-08-30
Key takeaways Young griffon vultures move frequently between sleeping sites in different locations, interacting with many friends. They get set in their ways as they age and roost in the same spots with the same individuals; older vultures follow the same paths. Roosts act as information hubs; older vultures may have a more thorough knowledge of where to find food resources and less need to learn about them from other vultures. If you’d rather be watching TV on your couch than dancing at the club, you might have something in common with aging ...

Not just a ‘bad guy,’ Tau also plays a ‘good guy’ role protecting our brains

2024-08-30
A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital, reveals that the protein Tau – a key player implicated in several neurodegenerative conditions including Alzheimer’s disease – also plays a positive role in the brain. Tau mitigates neuronal damage caused by excessive reactive oxygen species (ROS) or free radicals and promotes healthy aging. The study was published in Nature Neuroscience. “ROS ...

Doughnut-shaped region found inside Earth’s core deepens understanding of planet’s magnetic field

Doughnut-shaped region found inside Earth’s core deepens understanding of planet’s magnetic field
2024-08-30
A doughnut-shaped region thousands of kilometres beneath our feet within Earth’s liquid core has been discovered by scientists from The Australian National University (ANU), providing new clues about the dynamics of our planet’s magnetic field. The structure within Earth’s liquid core is found only at low latitudes and sits parallel to the equator. According to ANU seismologists, it has remained undetected until now. The Earth has two core layers: the inner core, a solid layer, and the outer core, a liquid layer. Surrounding the Earth’s core is the mantle. The ...

Study combines data, molecular simulations to accelerate drug discovery

2024-08-30
Researchers from the University of Cincinnati College of Medicine and Cincinnati Children’s Hospital have found a new method to increase both speed and success rates in drug discovery. The study, published Aug. 30 in the journal Science Advances, offers renewed promise when it comes to discovering new drugs. “The hope is we can speed up the timeline of drug discovery from years to months,” said Alex Thorman, PhD, co-first author and a postdoctoral fellow in the Department of Environmental and Public ...

NCT/UCC Dresden: Millions in funding from the Chan Zuckerberg Initiative for state-of-the-art imaging to accurately detect minute tumors

NCT/UCC Dresden: Millions in funding from the Chan Zuckerberg Initiative for state-of-the-art imaging to accurately detect minute tumors
2024-08-30
The imaging techniques currently used in biological research cannot penetrate into deeper tissue layers. In cancer treatment, this means that remnants of tumors or individual cancer cells at tumor margins and in lymph nodes are not visible. Doctors performing surgery are therefore repeatedly faced with the difficult question of whether all of the affected tissue has actually been removed. For the patient's quality of life, however, the complete removal of the tumor is just as essential as the preservation of healthy tissue ...

CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects
2024-08-30
To the known risk factors for cardiovascular disease—high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity—a new one has to be added: clonal hematopoiesis. This condition is triggered by acquired mutations in blood stem cells and was already known to be associated with an elevated cardiovascular risk. However, until now it was uncertain if clonal hematopoiesis was a cause or consequence of cardiovascular disease. Now, a new study published in Nature Medicine and carried out by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) resolves this critical debate ...

When the heat makes you disoriented

When the heat makes you disoriented
2024-08-30
Climate change is affecting ecosystems in many different ways. One of its consequences are increasingly longer and more intense periods of heat, which affect essential natural processes –  such as pollination. A team of researchers from Julius-Maximilians-Universität Würzburg (JMU) has now investigated in more detail how heat affects one particular player in these processes: The bumblebee. "Bumblebees are important pollinators in natural and agricultural systems. They therefore ...

Showcasing latest AI updates, Insilico Medicine attends 2024 EFMC International Symposium on Medicinal Chemistry

2024-08-30
Attracting around 1,000 participants from industry and academia, the XXVIII EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC) is supposed to take place in Rome, Italy from September 1-5, 2024. After the generative AI updates recently announced on the IMGAIA webinar, Insilico Medicine will be sharing more innovative details while exploring collaboration chances at Booth #50. EFMC-ISMC is a key symposium in the field of medicinal chemistry and drug discovery, and the symposium this year features ...

Novel chemical tool aims to streamline drug-making process

2024-08-30
COLUMBUS, Ohio – The invention of a tool capable of unlocking previously impossible organic chemical reactions has opened new pathways in the pharmaceutical industry to create effective drugs more quickly.   Traditionally, most drugs are assembled using molecular fragments called alkyl building blocks, organic compounds that have a wide variety of applications. However, because of how difficult it can be to combine different types of these compounds into something new, this method of creation ...

New discoveries about how mosquitoes mate may help the fight against malaria

New discoveries about how mosquitoes mate may help the fight against malaria
2024-08-30
Link to Google Drive folder containing images with caption and credit information: https://drive.google.com/drive/folders/1UM9rl47Xd_Bs-ov0HpVwC-rtUDonM3oJ?usp=sharing   Post-embargo link to release: https://www.washington.edu/news/2024/08/30/mosquito-swarm/     Embargoed by Current Biology For public release at 11 a.m. U.S. Eastern Time (8 a.m. U.S. Pacific Time) on Friday, Aug. 30, 2024   A high-pitched buzzing sound in your ear is an unmistakable sign that a female mosquito is out on the hunt — for they, not males, drink blood. Hearing ...

It’s worth challenging that troubling medical bill, study finds

2024-08-30
Many people who receive a problematic medical bill don’t challenge it – but new USC Schaeffer Center research shows they are likely missing out on a chance for financial relief. About 1 in 5 people said they recently received a medical bill they disagreed with or couldn’t afford, including 61.5% who said they contacted a billing office to address their concern, according to survey results published Aug. 30 in JAMA Health Forum. Most who reached out said they received some form of payment help or had their bill corrected. It’s ...

New study finds Medicare Advantage (MA) enrollees experience similar declines in frailty over one year compared with Traditional Medicare (TM) enrollees

2024-08-30
Enrollment in Medicare Advantage (MA) plans is not associated with altered frailty trajectories compared with enrollment in Traditional Medicare (TM), according to research published today in JAMA Network Open. In the article Frailty in Medicare Advantage Beneficiaries and Traditional Medicare Beneficiaries, lead author Sandra M. Shi, MD, MPH and colleagues suggest that more work is needed to better understand the health services needs of older adults with frailty. “A growing proportion of the population is enrolling in Medicare Advantage (MA), which typically ...

Autoimmune sequelae after Delta or Omicron variant SARS-CoV-2 infection in a highly vaccinated cohort

2024-08-30
About The Study: This cohort study observed no significantly elevated long-term risk of autoimmune sequelae after SARS-CoV-2 Delta and Omicron BA.1 or BA.2 variant infection, except for a modestly increased risk of inflammatory bowel disease and bullous skin disorders in the hospitalized subgroup during the predominance of the Omicron variant. Booster vaccination appeared to mitigate the risk of long-term autoimmune sequelae.  Corresponding Author: To contact the corresponding author, Liang ...

Racial disparities in cancer stage at diagnosis and survival for adolescents and young adults

2024-08-30
About The Study: The findings of this study suggest that racial disparities in cancer stage at diagnosis and survival exist among adolescent and young adult patients when disaggregated according to federal guidelines, which has health policy and funding implications. These results support the need for tailored interventions and informed public policy to achieve cancer care equity for all races.  Corresponding Author: To contact the corresponding author, Kekoa Taparra, MD, PhD, email ktaparra@stanford.edu. To ...

Structural equality and support index in early childhood education

2024-08-30
About The Study: This cohort study found that early childhood programming is associated with social determinants of health in adulthood. These findings reinforce the importance of early childhood education in addressing health disparities and contributing to healthier, more equitable communities and suggest that educational attainment is a key mechanism for health promotion. Corresponding Author: To contact the corresponding author, Arthur J. Reynolds, PhD, email ajr@umn.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.32050) Editor’s ...

Automated HER2 scoring in breast cancer images using deep learning and pyramid sampling

Automated HER2 scoring in breast cancer images using deep learning and pyramid sampling
2024-08-30
HER2 is a critical protein that plays a pivotal role in breast cancer cell growth and aggressiveness. Its expression level is a key indicator for treatment decisions, including the use of HER2-targeted therapies. Currently, HER2 status assessment relies heavily on immunohistochemical (IHC) staining of tissue slides followed by manual inspection by pathologists. This process, though widely adopted, suffers from several limitations, including poor reproducibility among pathologists and extended turnaround times. These challenges are further exacerbated in resource-constrained ...

Functional information offers individualized adaptive cancer therapies

Functional information offers individualized adaptive cancer therapies
2024-08-30
BUFFALO, NY- August 30, 2024 – A new editorial was published in Volume 11 of Oncoscience on July 19, 2024, entitled, “Functional information offers individualized adaptive cancer therapies.” As introduced in this editorial, the Oxford Computer Science Dictionary offers both general and technical definitions of information. Generally, information is anything that can cause a change in a human mind's opinion about the current state of the real world. Technically, information is anything that reduces the uncertainty of a system's state. Claude Shannon provided an objective measure of information, known as entropy (H), by mathematically defining ...

Low-quality video target detection based on EEG signal using eye movement alignment

Low-quality video target detection based on EEG signal using eye movement alignment
2024-08-30
In a research paper, scientists from the Beijing Institute of Technology proposed an event related potential (ERP) extraction method to solve the asynchronous problem of low-quality video target detection, designed the time-frequency features based on continuous wavelet transform, and established an EEG decoding model based on neural characterization. The average decoding accuracy of 84.56% is achieved in pseudo-online test. The new research paper, published July 4 in the journal Cyborg and Bionic Systems, introduces a low-quality ...
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