‘Mismatched’ transplants now safe, effective for blood cancer patients, study finds
2025-07-15
Advances in blood stem cell transplants now make it possible for people with blood cancers to get safe and effective “mismatched” transplants that will potentially cure their disease, new UVA Cancer Center research reveals. The advances will allow far more people to receive the lifesaving treatment.
Patients who could not find a perfect match traditionally have not received transplants because of the potential for graft-versus-host disease. This occurs when the immune system recognizes the transplanted cells as foreign and attacks them. This can be serious and, ...
New research helps narrow down uncertainties in near-term precipitation projections for the Asian Water Tower
2025-07-15
The Qinghai-Xizang Plateau (QP), often referred to as the "Asian Water Tower", is a vital source of water for nearly two billion people. Understanding how precipitation patterns in this region will change in the coming decades is crucial for water resource management and climate adaptation. However, projecting near-term precipitation changes has been challenging due to significant uncertainties in climate models.
A new study published in Atmospheric and Oceanic Science Letters addresses this issue by analyzing near-term (2026–2055) precipitation projections for the QP using 100 ensemble members from the MPI-ESM climate model. The research ...
AI tool accurately detects tumor location on breast MRI
2025-07-15
OAK BROOK, Ill. – An AI model trained to detect abnormalities on breast MR images accurately depicted tumor locations and outperformed benchmark models when tested in three different groups, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).
“AI-assisted MRI could potentially detect cancers that humans wouldn’t find otherwise,” said the study’s lead investigator Felipe Oviedo, Ph.D., a senior research analyst at Microsoft’s AI for Good Lab.
Screening mammography is considered the standard of care in breast ...
Researchers use OCT imaging to uncover how the fallopian tube transports embryos
2025-07-15
WASHINGTON — In a new mouse study, researchers have used optical coherence tomography (OCT) to uncover new insights into how the fallopian tube transports preimplantation embryos toward the uterus for pregnancy. These findings help lay the foundation for understanding certain causes of infertility and pregnancy complications in people.
The fallopian tube, also known as the oviduct, is a tubular structure that connects the ovary and the uterus. It is responsible for several critical processes that lead to pregnancy, including transporting eggs and sperm, hosting fertilization and transporting preimplantation embryos as they develop.
“Most of the oviduct’s ...
PolyU secures RGC theme-based research scheme funding to develop cost-effective and sustainable Co-GenAI model
2025-07-15
The Hong Kong Polytechnic University (PolyU) is committed to driving cutting-edge research that creates societal impact and technological advancement. Prof. YANG Hongxia, Executive Director of the PolyU Academy for Artificial Intelligence, Associate Dean (Global Engagement) of the Faculty of Computer and Mathematical Sciences, and Professor of the Department of Computing, has received funding from the Theme-based Research Scheme 2025/26 under the Research Grants Council for her pioneering project, “Collaborative Generative AI (Co-GenAI)”.
The project has been awarded total funding of HK$62.6 million, with HK$41.79 million provided by the RGC and the remaining ...
Van Andel Institute scientists develop technique for high-resolution single cell epigenetic analysis
2025-07-15
GRAND RAPIDS, Mich. (July 15, 2025) — Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help researchers better study the role of epigenetics in cancer and other diseases.
DNA methylation is an epigenetic mechanism that influences how and when the instructions in DNA are used without changing the DNA sequence itself. As a result, DNA methylation is a key player in many fundamental biological processes ...
The Lundquist Institute wins multi-year NIH grant exceeding $11 million to transform diagnosis and treatment of deadly mucormycosis
2025-07-15
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA (TLI) announced today that the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a new grant (P01AI186818) to Dr. Ashraf S. Ibrahim, PhD, a TLI Investigator, a Professor of Medicine at David Geffen School of Medicine at UCLA, and a leading authority on mucormycosis pathogenesis. The grant provides $2.2 million in first-year funding and $11,269,858 million in total projected support over ...
Review suggests ending adult boosters for tetanus, diphtheria
2025-07-15
The United States could safely drop tetanus and diphtheria booster shots for adults and save an estimated $1 billion a year, according to a new review led by researchers at Oregon Health & Science University.
The safety and savings depend on maintaining strong childhood vaccination rates, researchers emphasized.
“By maintaining high childhood vaccination coverage, we not only protect kids, but we may actually be able to reduce adult booster vaccinations,” said lead author Mark Slifka, Ph.D., professor of microbiology and immunology in the OHSU School of Medicine and the Oregon National Primate Research Center. “That would save $1 billion a year in the U.S. while maintaining ...
ESMT Berlin welcomes Rebecca Schaumberg to faculty
2025-07-15
On July 1, 2025, Rebecca Schaumberg joined ESMT Berlin as an assistant professor of organizational behavior.
Rebecca Schaumberg’s research combines psychological theory with business practice and focuses on the role of self-conscious emotions such as shame, guilt, pride, and embarrassment in organizational contexts. Her work shows how these emotions shape decision-making, leadership processes, and organizational cultures. Her research has been published in leading academic journals, including Psychological Science, Academy of Management Journal, and Organizational Behavior and Human Decision Processes.
Schaumberg ...
Blocking a little-known protein may offer new hope for devastating lung disease
2025-07-15
New York, NY, July 15, 2025—Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease. Their findings, demonstrated across cell cultures, preclinical models, and samples of human lung tissue, show that blocking Epac1 can slow the progression of the disease.
Published in the July 7 online issue of European Respiratory ...
Medieval medicine was smarter than you think – and weirdly similar to TikTok trends
2025-07-15
It turns out the Dark Ages weren’t all that dark! According to new research, medieval medicine was way more sophisticated than previously thought, and some of its remedies are trending today on TikTok.
A new international research project featuring faculty at Binghamton University, State University of New York reveals that people in the Middle Ages weren’t cooped up in castles, wallowing in superstition. They were developing health practices based on the best knowledge they had at the time – some of which mirror modern wellness trends.
“People were engaging with medicine on a much broader scale than had previously ...
FAU receives NIH grant to investigate amphetamine addiction
2025-07-15
Lucia Carvelli, Ph.D., associate professor of neuroscience at Florida Atlantic University’s Harriet L. Wilkes Honors College and a member of the FAU Stiles-Nicholson Brain Institute, has received a $571,675 grant from the National Institutes of Health to advance critical research into how amphetamines affect brain function. Her work could pave the way for new therapies targeting substance use disorders and dopamine-related neurological conditions such as ADHD.
Amphetamine and its derivatives – including methamphetamine – are among the most widely abused drugs worldwide. In the United States alone, more than 32,000 ...
Realizing on-site carbon nanotube photo-thermoelectric imaging
2025-07-15
Summary
Led by Assistant Professor Kou Li, a research group in Chuo University, Japan, has developed chemically enriched photo-thermoelectric (PTE) imagers using semiconducting carbon nanotube (CNT) films, resulting in the achievement of enhanced response intensity and noise reduction, that enables efficient remote and on-site inspections, according to a recent paper publication in Communications Materials. CNT film-based PTE imagers are crucial for multimodal non-destructive inspection, but conventional device ...
Most of us love memes. But are they a form of comics?
2025-07-15
COLUMBUS, Ohio – Once upon a time – way back in the twentieth century – people got their laughs from reading comics in the newspaper. Today, many of us get our chuckles by seeing (and sharing) humorous memes online.
But are these two cultural phenomena really that different? In a new article, comics scholar Michelle Ann Abate argues that memes are an important new type of digital comic.
“Memes use a lot of the same visual and verbal elements that go into a comic, and those elements function in a very similar way. So yes, memes ...
Novel biosensor allows real-time monitoring of sucrose uptake in plants
2025-07-15
Sucrose is a vital energy source in plants. It also drives growth and serves as an important signaling molecule during stress and development. Sucrose is a key product of photosynthesis and the primary form of sugar used for long-distance transport in plants. As such, its movement through plant tissues reveals much about its internal state. Yet, despite its importance, tracking sucrose in real time within living plants remains a persistent challenge.
One major challenge is the limited availability of in vivo sensors capable of capturing subtle physiological events, such as the movement of sucrose through plant tissues. Current ...
Korea University researchers reveal revealing how WEE1 drives cancer resistance to immunotherapy
2025-07-15
Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues. Some cancer cells exploit these checkpoints to avoid immune detection. Immune checkpoint blockade (ICB)—a therapy that uses antibodies to block these deceptive signals—can unleash the immune system to destroy cancer.
However, a major challenge in oncology remains: why do some tumors resist ICB?
In a landmark study, researchers from Korea University have discovered a surprising answer: the protein WEE1, traditionally known as a cell cycle regulator and tumor suppressor, can paradoxically drive immune resistance when located in the cytoplasm of cancer ...
Pusan National University researchers develop breakthrough deep learning model that enhances handheld 3D medical imaging
2025-07-15
Ultrasound (US) imaging is a widely employed diagnostic tool used for real-time imaging of various organs and tissues using ultrasonic sound waves. The waves are sent into the body, and images are created based on how the waves reflect off internal tissues and organs. It is used for guiding many medical procedures, including biopsies and injections, and is important for dynamic monitoring of blood vessels. When the US is combined with photoacoustic (PA) imaging, where laser light pulses are used to produce sound waves in tissues, the resulting ...
SLAS Discovery and SLAS Technology demonstrate research impact with 2024 impact factors
2025-07-15
Oak Brook, IL (July 11, 2025) – The Society for Laboratory Automation and Screening (SLAS) is pleased to announce the 2024 Journal Impact Factors (IF) for its two scientific journals, SLAS Discovery and SLAS Technology, as reported in the latest Journal Citation Reports (JCR) from Clarivate.
SLAS Technology achieved a substantial increase, rising 1.2 points to 3.7, highlighting its growing influence in the fields of laboratory automation and technology. SLAS ...
Disease-causing bacteria can deal with stink as long as they get a meal
2025-07-15
PULLMAN, Wash. -- Bacteria that cause intestinal infections typically avoid a stinky chemical — one that can kill them at high enough concentrations — inside human intestines, but they may actually swim toward it when a hearty meal is the reward.
“Imagine you’ve made a long journey and you’re starving,” said Arden Baylink, assistant professor. “You look for a place to eat, only to find it crowded with others and a line out the door. To make things worse, the crowd is hostile and pretty stinky. You face a dilemma: Is it worth staying to eat or should you leave?”
This is the problem faced by disease-causing ...
Mapping the metabolism of blood stem cells
2025-07-15
Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous. Their innovative research, made possible by highly sensitive low-input techniques, identifies the nutrient choline, as a key player in preserving youthful stem cell traits. This work offers profound insights into stem cell health and disease, suggesting ...
UK air quality improved since 2015 but targets still missed
2025-07-15
Air pollution across the UK dropped between 2015 and 2024, but dangerous levels are still reached too often, shows new research published today (Tuesday, 15 July) in Environmental Science: Atmospheres.
Scientists from the University of Reading studied pollution at more than 500 monitoring sites around the UK. They looked at three main types of air pollution which harm people's health. Two types of pollution got better over the decade. Nitrogen dioxide (NO2), which is mainly produced by traffic, fell by 35% on average at monitoring sites. Fine particles called PM2.5, which are small enough to get deep into lungs, dropped ...
Novel feature-extended analysis unlocks the origin of energy loss in electrical steel
2025-07-15
Magnetic hysteresis loss or iron loss is an important magnetic property that determines the efficiency of electric motors and is therefore critical for electric vehicles. It occurs when the magnetic field within the motor core, made up of soft magnetic materials, is repeatedly reversed due to the changing flow of current in the windings. This reversal forces tiny magnetic regions called magnetic domains to repeatedly change their magnetization direction. This change is, however, not perfectly efficient and results in energy loss. ...
Scientists identify why some heart rhythm drugs heighten risks when sodium levels drop
2025-07-15
New research explains how low levels of the electrolyte sodium in the blood can disrupt the timing of the heartbeat in patients taking widely used rhythm-control medications such as flecainide, which is commonly prescribed for atrial fibrillation and other fast or irregular heart rhythms.
The study, by Virginia Tech researchers at the Fralin Biomedical Research Institute in the journal Heart Rhythm, was conducted using guinea pig hearts and showed that blocking cardiac sodium channels with commonly prescribed medicine such as flecainide can make the heart’s electrical conduction unusually sensitive to even modest reductions ...
Jaguar population increases after wildfire and drought, indicating area’s role as climate refuge
2025-07-15
CORVALLIS, Ore. – Following a large-scale wildfire, more jaguars migrated to a study site in the Brazilian wetlands that already had the largest population density of jaguars in the world, a new study found.
“Finding even more jaguars and other mammals in the study area following the 2020 wildfire and extreme drought suggests that it may serve as a climate refuge, buffering the effects of extreme climate events,” said Charlotte Eriksson, a post-doctoral scholar at Oregon State University.
The 36,700-acre site is a seasonally ...
A new architecture at the heart of molecules
2025-07-15
Can you imagine a life-saving molecule whose “twin” is a deadly poison? As surprising as it may seem, this chemical reality is known as “chirality”. Like a right hand and a left hand, two molecules can have the same composition, but a different shape and arrangement in space. And this difference can change everything. Understanding and controlling this phenomenon is crucial to drug design. A team from the University of Geneva (UNIGE), in collaboration with the University of Pisa, has developed a new family of remarkably stable chiral molecules. This work opens up new prospects ...
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