CHICAGO — Today at ADLM 2025 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), researchers will unveil a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard — and that could translate to vastly improved patient outcomes. A second study highlights how certain generative AI tools can empower adolescents by helping them to gather useful medical information. Together, these findings spotlight the potential of AI to make a profound, positive difference in people’s ...

Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4). Biologics targeting specific pathways—TNF-α, IL-17, IL-12/23, IL-4/13, PD-1/PD-L1—revolutionize treatment but trigger immune drift, shifting CD4+ T-cell polarization and causing adverse skin reactions. This review synthesizes mechanisms, clinical manifestations, and management strategies. Mechanisms of Immune Drift by Biologic Class (Summarized in Table 1) 1. TNF-α Inhibitors (Etanercept, Infliximab, Adalimumab) Mechanism: Blocking ...

Simple technology that harnesses ultraviolet light to ‘zap’ airborne viruses has been shown to significantly lower the number of respiratory infections in aged care facilities, paving the way for smarter infection control. Adapted by scientists from Flinders Health and Medical Research Institute  (FHMRI) and SAHMRI, the technology is based on using germicidal ultraviolet (GUV) appliances which purify the air with UV-C light rays and deactivate harmful micro-organisms like viruses and bacteria. The new study published in JAMA Internal Medicine trialled commercially-available GUV appliances in aged care facilities ...

Researchers at the University of Tokyo explored how female body odor can influence behaviors in men. They found certain scent compounds in female body odor increased during ovulation and can subtly influence how men feel. When these scents were added to armpit odor samples, men rated them as more pleasant and faces associated with the samples as more attractive. The scents also seemed to reduce stress. The team states this is not evidence of pheromones in humans, but that smell might subtly shape how we people interact. While they’re a common staple of pop culture, especially in romantic comedies, pheromones, behavior-altering ...

UNDER EMBARGO UNTIL 16:00 UK TIME (11:00 AM ET) ON MONDAY 28 JULY 2025 New insights could help phages defeat antibiotic resistant bacteria Researchers at the University of Southampton have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance. Phages are seen as a promising alternative treatment to antibiotics. Unpicking how bacteria protect themselves, and how phages might overcome these defences, could be a significant step in defeating antibiotic resistant bacteria. Phages, ...

Cambridge, MA – Scientists often seek new materials derived from polymers. Rather than starting a polymer search from scratch, they save time and money by blending existing polymers to achieve desired properties. But identifying the best blend is a thorny problem. Not only is there a practically limitless number of potential combinations, but polymers interact in complex ways, so the properties of a new blend are challenging to predict. To accelerate the discovery of new materials, MIT researchers ...

About The Study: In this nationwide cohort study, no increased risk of 29 adverse events was observed after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage in approximately 1 million adults.  Corresponding Author: To contact the corresponding author, Niklas Worm Andersson, MD, PhD, email nian@ssi.dk. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.23557) Editor’s Note: Please see the article for additional information, ...

About The Study: The findings of this study suggest that patients with type 2 diabetes may experience substantially more adverse financial outcomes compared with patients without diabetes, highlighting the need to consider patient financial health when treating type 2 diabetes, particularly for patient groups at higher risk.  Corresponding Author: To contact the corresponding author, Cazilia Loibl, PhD, CFP, email loibl.3@osu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.23453) Editor’s ...

Embargoed until 11 a.m. ET, July 28, 2025   In a first-of-its-kind study, researchers used a unique dataset to show that patients with type 2 diabetes have significantly worse financial outcomes than other patients.   Findings showed diabetes patients fared worse on all seven financial outcomes studied, including below-prime credit scores, medical and non-medical debt in collections, 60-plus-day delinquent debt, debt charge-offs, bankruptcy filings and foreclosure.   The diabetes patients in this study were compared to people who had a blood test ...

Coronary heart disease (CHD), characterized by atherosclerosis-induced myocardial ischemia, remains a leading cause of mortality in China. Safflower yellow pigments (SYPs), the primary bioactive components of Carthamus tinctorius L., consist mainly of quinochalcone C-glycosides, with hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) as key constituents. This review synthesizes evidence on SYPs' mechanisms, therapeutic applications, and future directions in CHD management. Chemical Composition and Pharmacokinetics SYPs comprise over 20 identified compounds, including HSYA and AHSYB, which confer cardiovascular protection, anti-inflammatory, and antioxidant activities. ...

“TraMA is likely to be of particular value to researchers interested in understanding the biological processes underlying health and aging, and for social, psychological, epidemiological, and demographic studies of health and aging.” BUFFALO, NY — July 28, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled “Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA).” In ...

TORONTO, ON July 28, 2025 A new research article published in the Journal of Participatory Medicine unveils how successive waves of digital technology innovation have empowered patients, fostering a more collaborative and responsive health care system. The paper, titled "From Internet to Artificial Intelligence (Al) Bots: Symbiotic Evolutions of Digital Technologies and e-Patients," explores the symbiotic evolution of digital health tools and the increasingly engaged e-patient. The concept of the e-patient, defined as an individual "equipped, enabled, empowered, and engaged" in their health, has been propelled forward by advancements spanning ...

Leishmaniasis, a neglected tropical disease caused by Leishmania parasites, affects millions globally. Current synthetic treatments face limitations including toxicity, cost, and resistance. Phytochemicals from medicinal plants offer promising alternatives. This mini-review synthesizes preclinical mechanisms of plant-derived compounds against leishmaniasis, focusing on mitochondrial disruption, immunomodulation, and redox imbalance. Key Antileishmanial Mechanisms 1. Membrane Disruption & ...

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today announced the recipients of its 2025 Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership and Meritorious Service Awards. These prestigious honors will be presented in November during the AMP 2025 Annual Meeting & Expo in Boston. Award for Excellence in Molecular Diagnostics Elaine R. Mardis, Ph.D. Co-executive Director, Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children’s Hospital Rasmussen Nationwide Foundation Endowed Chair in Genomic ...

Usually, light waves can pass through each other without any resistance. According to the laws of electrodynamics, two light beams can exist in the same place without influencing each other; they simply overlap. Light saber battles, as seen in science fiction films, would therefore be rather boring in reality. Nevertheless, quantum physics predicts the effect of “light-on-light scattering”. Ordinary lasers are not powerful enough to detect it, but it has been observed at the CERN particle accelerator. Virtual particles can literally emerge from nothing for a short time, interact with the photons and change their direction. The effect is extremely small, ...

A new study finds that White students visit academic advisers the least, but have the highest academic benefits, in terms of GPA and graduation rates, compared to nonwhite students and international students. In higher education, substantial gaps exist between White and nonwhite students, with a greater number of White students graduating in fewer years and receiving higher grades than many other groups. Prior research shows that nonwhite students are less likely to engage with faculty members, but there is a dearth of information related to interactions with academic advisers—staffers ...

A frog croaks from a walking trail. A hiker snaps a photo and uploads it to iNaturalist. That single act — one person, one amphibian and one click — feeds into a growing global dataset that scientists now use to map shifting species ranges, detect invasive threats and even discover new species. An international study led by researchers at the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) shows how iNaturalist, the global technology platform through which everyday people share ...

UNIVERSITY PARK, Pa. — Though scientists have long understood how lightning strikes, the precise atmospheric events that trigger it within thunderclouds remained a perplexing mystery. The mystery may be solved, thanks to a team of researchers led by Victor Pasko, professor of electrical engineering in the Penn State School of Electrical Engineering and Computer Science, that has revealed the powerful chain reaction that triggers lightning. In the study published today (July 28) in the Journal ...

Hybrid water electrolysis (HWE) is an emerging field that aims to overcome some of the limitations of conventional water electrolysis (CWE) for the production of green hydrogen. In CWE, two reactions take place at each of the electrodes (anode and cathode): one reaction produces hydrogen at the cathode (the hydrogen evolution reaction) and the other produces oxygen at the anode (the oxygen evolution reaction, OER). The concept of hybrid water electrolysis revolves around replacing the anode reaction of CWE (the OER), which is inefficient and requires ...

There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease. Often referred to as the “bad” cholesterol, elevated levels of LDL can clog arteries and significantly increase the risk of heart attacks and strokes. In an invited editorial published in the current issue of Trends in Cardiovascular Medicine, researchers from Florida ...

DALLAS, July 28, 2025 — People in 15 regions across the U.S. will soon benefit from the American Heart Association’s Cardiovascular-Kidney-Metabolic Health Initiative™, designed to improve treatment of the interconnected conditions that lead to heart disease and stroke. The initiative began with five regions in February and has now expanded to include the final 10 regions. The regions include states, cities and metro areas. The initiative, supported by founding sponsors Novo Nordisk and Boehringer Ingelheim, supporting sponsor Novartis Pharmaceuticals Corporation and champion sponsor DaVita, will enroll 150 health care ...

Alexandria, VA – The AADOCR is now accepting applications for Cohort 6 of the Mind the Future Program, thanks to the generous support of CareQuest Institute for Oral Health.  The AADOCR Mind the Future program has been instrumental in fostering five cohorts of early-career investigators in the dental, oral, and craniofacial (DOC) research workforce. The network's principal purpose has been to establish a robust and enduring national mentoring program centrally managed by AADOCR. The overarching ...

Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer. There is currently no treatment for CLD other than liver transplantation. Vitamin D is commonly consumed for enhanced bone health. This study opens exciting possibilities for repurposing an inexpensive supplement as a complementary therapy for liver diseases. Prof. Hyo-Jung Kwon from the College of Veterinary Medicine, Chungnam National University in Daejeon, Republic of Korea, and his colleagues ...

University research is where innovative technological breakthroughs originate. As a result, a number of proactive universities provide substantial resources and support to their academic researchers to help increase the number of all ventures. However, despite receiving this extensive support and having access to the best scientific knowledge, many academic entrepreneurs are not as successful as their corporate counterparts. While this sounds like a contradiction, there is enough empirical evidence explaining just why this could be happening. With this in mind, Professor Alex Coad from the Waseda Business School, Waseda University, Japan, critically analyzes the differences ...

Consider the delicate web of fat in a Wagyu steak. The “marbling” that makes carnivore connoisseurs swoon is a visual heuristic for quality flavor. Now, a new study suggests the very same marbling of fat inside our own muscles points to trouble. This condition, known as intramuscular adipose tissue, or IMAT, has long been recognized by scientists as a strong indicator of poor health. It’s linked to a wide range of diseases: obesity, Type 2 diabetes, neuromuscular disorders (including Duchenne muscular dystrophy) and neurogenerative conditions such as ALS. In some cases, ...