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Kindness counts—even to a five-day-old baby

2025-07-14
They’ve barely opened their eyes, but newborn babies already seem to prefer nice behaviours. New research reveals that infants just five days old can tell the difference between two distinct forms of prosocial and antisocial behaviour—and they prefer the prosocial. This suggests that some parts of how humans understand and evaluate the social world may be built into the brain from birth. “These babies have almost no experience with the social world, and yet they’re already picking up on friendly versus unfriendly interactions, on helping versus hindering. That could be telling us something ...

Endocrine Society guideline calls for increased screening for common cause of high blood pressure

2025-07-14
SAN FRANCISCO—Endocrine Society experts encouraged more widespread screening for a common hormonal cause of high blood pressure known as primary aldosteronism in a new Clinical Practice Guideline released today. “Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline” was published online and is being presented at ENDO 2025, the Society’s annual meeting. A significant minority of people who are diagnosed with hypertension, or high blood pressure, actually have undiagnosed primary aldosteronism. An estimated 5% to 14% of people with high blood pressure seen in primary care and up to 30% seen in referral centers have primary ...

Macromolecular gene delivery systems: advancing non-viral therapeutics with synthetic and natural polymers

2025-07-14
Gene therapy has emerged as a revolutionary approach to treating genetic disorders by directly addressing underlying genetic abnormalities. However, the success of gene therapy hinges on the efficient and safe delivery of therapeutic genes to target cells. Traditional viral vectors, despite their high transfection efficiency, face limitations such as immunogenicity, limited cargo capacity, and risks of insertional mutagenesis. Non-viral gene delivery systems, particularly those based on macromolecular carriers, have gained prominence as safer and more versatile alternatives. This review explores the advancements in synthetic and natural polymer-based gene delivery systems, highlighting ...

Study finds political instability, environmental conditions, and social inequality accelerate aging

2025-07-14
New study redefines healthy aging as an environmental, social, and political phenomenon, and calls on public health strategies to expand beyond lifestyle prescriptions to address structural inequalities and governance deficits A groundbreaking international study of 161,981 participants across 40 countries published in Nature Medicine today, [Monday , 14th July 2025] reveals that air pollution, social inequality, and weak democratic institutions substantially accelerate aging. The collaborative study involves leading researchers from the Global Brain Health Institute in Trinity ...

New insights into malaria: Proteins in the blood can reveal the severity of the disease

2025-07-14
Researchers at Karolinska Institutet have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients. The study, published in the journal Immunity, was conducted on 72 adult travellers diagnosed with malaria at Karolinska University Hospital after returning from tropical regions. By analysing blood samples from these individuals, who were followed for a year, the researchers were able to identify around ...

Delayed hypertension diagnosis and its association with cardiovascular treatment and outcomes

2025-07-14
About The Study: The findings of this study suggest that delays in hypertension diagnosis were common and significantly associated with delays in treatment initiation and adverse cardiovascular outcomes, underscoring the need for earlier identification and intervention.  Corresponding Author: To contact the corresponding author, John E. Brush Jr, MD, email jebrush@sentara.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.20498) Editor’s Note: Please see the article for additional ...

GLP-1 receptor agonists in idiopathic intracranial hypertension

2025-07-14
About The Study: Glucagon-like peptide 1 receptor agonist (GLP-1 RA) therapy in idiopathic intracranial hypertension is associated with significant reductions in medication use, symptoms/signs, and procedural interventions, suggesting its potential as a management strategy. Further prospective studies are warranted to confirm these findings. Corresponding Author: To contact the corresponding author, Dennis J. Rivet II, MD, email dennis.rivet@vcuhealth.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2025.2020) Editor’s Note: Please ...

Integrating diet and physical activity when prescribing GLP-1s—lifestyle factors remain crucial

2025-07-14
About The Article: This article provides practical strategies for symptom management for patients receiving glucagon-like peptide-1 and dual receptor agonists (GLP-1 RAs) to manage weight and suggests interventions supporting muscle and nutrient preservation during GLP-1 RA treatment.  Corresponding Author: To contact the corresponding author, JoAnn E. Manson, MD, DrPH, email jmanson@bwh.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2025.1794) Editor’s ...

More research needed to explore potential racial, gender and socioeconomic differences in stroke treatment and recovery

2025-07-14
FOR IMMEDIATE RELEASE: July 14, 2025 CONTACT: Camille Jewell cjewell@vancomm.com or 202-248-5460   NASHVILLE — Research presented today at the Society of NeuroInterventional Surgery’s (SNIS) 22nd Annual Meeting included three studies that explored the differences in treatment and recovery options for patients across racial, gender and socioeconomic lines in a large telestroke network in Pennsylvania and a university medical center in Rhode Island.   Telestroke treatment aims to improve care for people with stroke symptoms who live far from comprehensive stroke centers — hospitals that offer a full ...

Prostate cancer cells survive treatment by storing fat in low oxygen conditions

2025-07-14
“[…] manipulating LD dynamics represents a promising strategy to overcome hypoxia-induced resistance to ferroptosis and improve the success of PCa treatment.” BUFFALO, NY – July 14, 2025 – A new research paper was published in Volume 16 of Oncotarget on June 25, 2025, titled “Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer.” In this study, researchers led by Shailender S. Chauhan and Noel A. Warfel from the University of Arizona discovered that prostate cancer cells survive treatment ...

Novel open-source diagnostic tool offers affordable, reliable pathogen detection for resource-limited settings

2025-07-14
A bottleneck in ensuring access to widespread molecular diagnostics, especially in low- and middle-income countries, has been the high cost and logistical complexities associated with rapid, point-of-care tests. Now, a collaborative research effort outlined in a Life Science Alliance (LSA) study to be published July 14, 2025 has addressed these challenges by developing a lyophilized (freeze-dried) open-source reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for pathogen detection. This method, successfully applied to COVID-19, aims to make the diagnostics more accessible and affordable globally. In ...

Answers to existence of alien life might be found in Earth’s deep-sea volcanoes

2025-07-14
AMHERST, Mass. — While popular culture commonly depicts extraterrestrial life as little green men with large, oval-shaped heads, it’s most likely that if there is life beyond our planet and within our solar system, it is microbial. Recently, NASA awarded University of Massachusetts Amherst microbiologist James Holden $621,000 to spend the next three years using his expertise to help predict what life on Jupiter’s moon Europa might look like. For that, Holden turned to an unexpected place: the volcanoes a mile beneath our own oceans. Jupiter’s moon, Europa, has a frozen surface, but astronomers believe that beneath all that ice lies a salty, liquid ocean ...

SwRI evaluates effects of hydrogen and natural gas blends on storage tanks

2025-07-14
SAN ANTONIO — July 14, 2025 — Southwest Research Institute (SwRI) is taking on the challenges of a hydrogen-powered future. In collaboration with NYSEARCH, a nonprofit research and development organization for the gas industry serving utility members across North America, SwRI is investigating how blending hydrogen into liquid natural gas (LNG) could affect the integrity of the LNG storage tanks. Natural gas is widely used to power appliances and heat homes. By blending hydrogen into ...

New study reveals widespread and overlooked flooding across NC

2025-07-14
A new study from UNC-Chapel Hill reveals that repetitive flooding in North Carolina is far more common and more widespread than previously recognized, with over 20,000 buildings flooding multiple times between 1996 and 2020. The study, which mapped 78 flood events across roughly three-quarters of the state, fills a major gap in understanding the full impacts of flooding on communities well beyond the state’s coastal floodplains.  Until now, detailed flood maps have existed for only a handful of past events. The research team created high-resolution maps for more than 70 previously unmapped floods, linking them to the exact locations ...

In a competitive world, mean leaders look smart

2025-07-14
People who view the world as a savage social jungle are more likely to admire antagonistic leaders, praising their competence, while those who see the social world as cooperative and benign might just call those leaders clueless, according to research published by the American Psychological Association. “Why do some people see antagonistic behavior in leaders – especially when it’s particularly mean or forceful or disagreeable – as a sign of incompetence, while others view it as a mark of savvy leadership?” said Christine Nguyen, a doctoral student at Columbia ...

New study highlights how perceived economic inequality undermines individual well-being across 71 countries

2025-07-14
New research published in Social Psychological and Personality Science shows that awareness of economic disparity affects happiness, meaning, harmony and spiritual well-being. A comprehensive new study examining data from 71 countries suggests that perceiving high levels of economic inequality significantly undermines individual well-being across multiple dimensions of human flourishing. The research provides crucial insights into how awareness of economic disparity affects not just happiness, but also people's sense of meaning, harmony, and spirituality. Led by researcher ...

The heat survival code of plants: The hidden mechanism of RNA splicing uncovered

2025-07-14
While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It’s a question many have wondered—and now, science has an answer. A research team led by Dr. Hye sun Cho at the Plant Systems Engineering Research Center of the Korea Research Institute of Bioscience and Biotechnology(KRIBB) has uncovered, for the first time at the molecular level, the mechanism by which plants adapt and survive under heat stress. The breakthrough is expected to greatly ...

How plants survive drought: The unsuspected role of myosin XI in guard cells

2025-07-14
With intensifying global warming and climate change, drought has become a major threat to global agriculture, impacting crop yields and food security. To survive such adverse events, plants have evolved several strategies. One such strategy to counteract water scarcity is ‘stomatal closure,’ where stomata—the tiny pores on leaf surfaces responsible for gaseous exchange—close to limit water loss. This process is regulated by the plant hormone abscisic acid (ABA), which plays a crucial ...

Pusan National University researchers unveil game-changing UV-fueled shape-shifting and shape-fixing smart materials

2025-07-14
Magnetic micropillar arrays consist of tiny, vertical pin-shaped structures, arranged in a grid-like pattern. These micropillars can change their shape to a pre-programmed geometry when exposed to a magnetic field. They are made from magnetically responsive composites, comprising rubbery polymers like polydimethylsiloxane (PDMS) embedded with magnetic particles. These composites can change their shape and recover repeatedly without any deterioration. Unfortunately, conventional magnetic micropillar arrays can only hold their changed shape temporarily while the magnetic field is being applied. Previous studies have explored various approaches to address this issue, including water-soluble ...

Landmark study in cell introduces first-of-its-kind optogenetic screening platform for drug discovery

2025-07-14
REDWOOD CITY, CA — July 14, 2025 — A landmark study published in Cell has unveiled a first-of-a-kind optogenetic screening platform, developed by scientists at Integrated Biosciences, a biotechnology company integrating optogenetics, chemistry and AI to discover small molecule therapeutics for age-related diseases. The new peer-reviewed publication demonstrates the platform’s capabilities by applying it to the integrated stress response (ISR), a key aging- and disease-associated signaling pathway implicated in neurodegeneration, cancer and viral infection.   In the Cell study, Integrated Biosciences scientists used optogenetic control to selectively activate the ...

Measuring air pollutants in real time: ERC proof of concept grant for TU Graz physicist

2025-07-14
Volatile air pollutants such as nitrogen dioxide and ozone are only monitored loosely in the EU. Separate devices are used for each individual pollutant, and real-time monitoring is not possible. Birgitta Schultze-Bernhardt from the Institute of Experimental Physics at Graz University of Technology (TU Graz) would like to simplify and significantly improve these measurements. In her MULTI TRACE research project, she is developing a portable device that can determine the concentration of several gaseous pollutants in ambient air with the utmost accuracy ...

How new genes get switched on

2025-07-14
Most genes are ancient and shared across species. But a small subset of genes are relative newcomers, spontaneously emerging from stretches of DNA that once encoded nothing at all. Now, after nearly a decade of charting these genes in fruit flies, researchers have discovered how these de novo genes are regulated. In complementary studies, in Nature Ecology & Evolution and PNAS, the team showed how transcription factors and genomic neighbors switch these genes on and integrate them into cellular networks—the first studies to identify these master regulators. Together, the findings shed light on how new genes become ...

Regrowing hearing cells: New gene functions discovered in zebrafish offer clues for future hearing loss treatments

2025-07-14
KANSAS CITY, MO — July 14, 2025 — While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems. In contrast, animals like fish, frogs, and chicks regenerate sensory hair cells effortlessly. Now, scientists at the Stowers Institute for Medical Research have identified how two distinct genes guide the regeneration of sensory cells in zebrafish. The discovery improves our understanding of how regeneration works in zebrafish and may guide future studies ...

Air pollution cuts in East Asia likely accelerated global warming

2025-07-14
The cleanup of air pollution in East Asia has accelerated global warming, a new study published today (Monday, 14 July) in the journal Communications Earth and Environment has found. Global warming, driven primarily by emissions of greenhouse gases, has been accelerating for the past 15 years, leading to record-breaking surface temperatures. Over the same period, countries in East Asia have made strong efforts to clean up air pollution, which is important for public health. The largest air pollution clean-up has been made ...

Fighting leukemia by breaking a hidden cell loop

2025-07-14
Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival. The findings, published in Nature Communications, offer new hope for treating and preventing cancer. Hollings researcher Sophie Paczesny, M.D., Ph.D., co-leader of the Cancer Biology and Immunology Research Program, led the multidisciplinary research ...
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