Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men. A new sex-specific study from McGill University has found that there are differences between male and female genes and how they relate to depression. In a study of more than 270,000 individuals, the researchers found that sex-specific prediction methods were more accurate in forecasting an individual’s genetic risk of developing depression than prediction methods that did not specify sex. The researchers found ...

A study with people who inject drugs evaluated a minimally invasive test based on dried blood spots (DBS) for the monitoring of hepatitis C virus (HCV) infection. The use of DBS samples for HCV RNA detection and genotyping was shown to effectively assess cure after treatment and to differentiate between reinfection and treatment failure. The results support the viability of decentralizing treatment and post-treatment monitoring for people who inject drugs, who frequently face challenges accessing the healthcare system. The study, which has been published in the Journal of Medical Virology, was carried out as part of a project with support from the "Conquering ...

AMHERST, Mass. – University of Massachusetts Amherst’s Department of Mathematics and Statistics is offering 30 three-year scholarships to a diverse cohort of students majoring in mathematics and statistics, thanks to a $1.5 million dollar grant from the National Science Foundation (NSF). The six-year project, called Enhancing Underrepresented Participation in Mathematics & Statistics: Mentoring from Junior to Master’s, will welcome its first cohort in the Fall of 2023, and will support each student for their junior and senior years, as well as through a one-year master’s program. The program will accept ...

Semiconducting single-walled carbon nanotubes (s-SWCNTs) are being used to develop a third generation of optimized shortwave infrared photodetectors that will improve pixel size, weight, power consumption, performance and cost over photodetectors made from traditional materials.   Ultrasensitive shortwave infrared photodetectors, which detect a subset of shortwave infrared light wavelengths outside of the visual spectrum, have many potential applications, including night surveillance, navigation during poor weather conditions, fiber optic communications and semiconductor quality control.  Shortwave ...

More than 85% of the world’s bird, mammal, and amphibian species live in mountains,  particularly in forest habitats, but researchers report in the journal One Earth on March 17 that these forests are disappearing at an accelerating rate. Globally, we have lost 78.1 million hectares (7.1%) of mountain forest since 2000—an area larger than the size of Texas. Much of the loss occurred in tropical biodiversity hotspots, putting increasing pressure on threatened species. Though their rugged location once protected mountain forests from deforestation, they have been increasingly exploited since the turn of ...

The livelihoods of millions of people who live in river deltas, among the world’s most productive lands, are at risk. Created where large rivers meet the ocean and deposit their natural sediment load, river deltas are often just a few meters above sea level. And while they make up less than 0.5 % of the world’s land area, river deltas contribute more than 4 % of the global GDP, 3% of global crop production, and are home to 5.5 % of the world’s population. All of these values are highly vulnerable to imminent global environmental change, according to a new Stanford University-led study. “It is often not rising seas, but sinking land due to human activities that ...

WASHINGTON (March 17, 2023)— Medicaid beneficiaries face barriers in accessing medical care – and that includes contraceptive care. A new study finds that despite birth control being an essential health service, all primary care physicians that see them may not be offering Medicaid patients some of the most effective, longer-acting birth control methods. While nearly half (48%) of primary care physicians who treat Medicaid patients provided prescription contraception like the birth control pill, only 10% provided longer-acting methods like IUDs ...

About The Study: In this study of Oregon residents in households of at least two members, the findings suggest that household prescription availability is associated with increased odds of opioid overdose for others in the household, even if they do not have their own opioid prescription. These findings underscore the importance of educating patients about proper opioid disposal and the risks of household opioids.  Authors: Michelle A. Hendricks, Ph.D., of Comagine Health in Portland, Oregon, is the corresponding ...

About The Study: Long-term heat and cold exposure from the second trimester until four weeks after birth was associated with newborn lung volumes, especially among female newborns, in this study of 343 mother-child pairs. The findings suggest an association between ambient temperature and newborns’ respiratory systems and underlines the vulnerability of pregnant women and their future children to climate change.  Authors: Ariane Guilbert, M.Sc., and Johanna Lepeule, Ph.D., of Universite Grenoble Alpes in La Tronche, France, are the corresponding authors.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.3376) Editor’s ...

Ice surfaces have a thin layer of water below its melting temperature of 0℃. Such premelting phenomenon is important for skating and snowflake growth. Similarly, liquid often crystallizes into a thin layer of crystal on a flat substrate before reaching its freezing temperature, i.e. prefreezing. The thickness of the surface layer usually increases and diverges as approaching the phase transition (such as melting and freezing) temperature. Besides premelting and prefreezing, whether similar surface phenomenon ...

Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying. Although these inhibitors, called TKIs, can be very useful in fighting certain cancers, they also cause serious inflammatory side effects that limit their use. A Japanese research team has discovered the underlying mechanism that causes this inflammation. "This study revealed the underlying mechanism by which the TKIs cause inflammation, and therefore provides the molecular basis that is essential to overcome the inflammatory-based ...

Publishing in the International Journal of Extreme Manufacturing (IJEM), researchers from Harbin Institute of Technology, Huazhong University of Science and Technology, Guizhou University and Ruhr-University Bochum present a brief review on the application of numerical simulations in addressing the impact of properties and microstructures of workpiece materials on the diamond cutting mechanisms of different types of workpiece materials, such as metallic, hard brittle materials and composite materials. In addition, the effect of applying an external energy field to the diamond cutting of difficult-to-cut materials is also discussed. The anisotropic deformation ...

A new simulation approach named eTLE aims to improve the precision of a primary tool for estimating neutron behaviours in 3D space. This study examines the approach in detail – validating its reliability in predicting the scattering of neutrons in crystalline media. Tripoli-4® is a tool used by researchers to simulate the behaviours of interacting neutrons in 3D space. Recently, researchers developed a new ‘next-event estimator’ (NEE) for Tripoli-4®. Named eTLE, this approach aims to increase Tripoli-4®’s precision using Monte ...

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, to be published March 17 in the Journal of Experimental Medicine, uses a new, highly versatile form of CRISPR-based genome editing with the potential to correct a wide variety of disease-causing genetic mutations. Researchers have previously used genome editing to restore the vision of mice with genetic diseases, such as Leber congenital amaurosis, that affect ...

Deyi Li from the Chinese Association for Artificial Intelligence believes that humans and machines have a mutually beneficial relationship. His paper on machine intelligence, which was published Feb. 15 in Intelligent Computing, a Science Partner Journal, builds on five groundbreaking works by Schrödinger, the father of quantum mechanics, Turing, the father of artificial intelligence, and Wiener, the father of cybernetics. Schrödinger and beyond: Machines can think and interact with the world as time goes by. ...

Ikoma, Japan – Rho GTPases have a crucial role in the orchestration of cell movements. Cells use Rho GTPases to coordinate cytoskeletal reorganization in dynamically changing environments. Among these RhoGTPases, Cdc42 and Rac1 promote cytoskeletal formation, whereas RhoA is involved in myosin II-mediated cytoskeletal retraction and formation. Simultaneous live observations of multiple GTPase activities and cell morphology changes by specific biosensors and the resulting spatiotemporal data might help to determine the coordinated regulation of ...

Dibaryons are the subatomic particles made of two baryons. Their formations through baryon-baryon interactions play a fundamental role in big-bang nucleosynthesis, in nuclear reactions including those within stellar environments, and provide a connection between nuclear physics, cosmology and astrophysics. Interestingly, the strong force, which is the key to the existence of nuclei and provides most of their masses, allows formations of numerous other dibaryons with various combinations of quarks. However, we do not observe them abound -- deuteron is the only known stable dibaryon. To resolve this apparent dichotomy, it is essential to investigate ...

Graphene’s 2D nature, single molecule sensitivity, low noise, and high carrier concentration have generated a lot of interest in its application in gas sensors. However, due to its inherent non-selectivity, and huge p-doping in atmospheric air, its applications in gas sensing are often limited to controlled environments such as nitrogen, dry air, or synthetic humid air. While humidity conditions in synthetic air could be used to achieve controlled hole doping of the graphene channel, this does not adequately mirror the situation ...

The Electronics and Telecommunications Research Institute(ETRI) has developed a reading comprehension education AI technology that allows you to learn foreign language listening, speaking, and reading by talking to an artificial intelligence (AI) tutor. It is expected to be of great help in the spread of AI-based language education services. The Electronics and Telecommunications Research Institute(ETRI) introduced a reading comprehension AI tutor, an artificial intelligence technology for reading education, that introduced deep learning-based dialog processing technology to reading comprehension education for the first time in the world. Through ...

DURHAM, N.C., March 17, 2023 – Burt’s Bees, the #1 dermatologist recommended natural skin care brand,* announced its latest research findings on the benefits of a topical bakuchiol-containing sunscreen in treating redness and pigmentation of photodamaged facial skin. Burt’s Bees also published research findings on a topical treatment in improving the appearance of post-inflammatory hyperpigmentation associated with acne. These studies, available online via ePoster, have been developed for the American Academy of Dermatology 2023 Annual Meeting (AAD) Mar. 17–21, 2023, ...

Staphylococcus aureus. You may have had it in connection with a wound infection. In most cases, it will pass without treatment, while severe cases may require antibiotics, which kills the bacteria. This is the case for the majority of the population. In fact, many of us – though we feel perfectly fine – carry staphylococci in the nose, a good, moist environment in which the bacteria thrive. However, more and more staphylococci are becoming resistant to antibiotics (also known as multi resistant staphylococcus aureus or MRSA), and these infections can be difficult to treat. “Antibiotics resistance ...

It is extremely rare for a new plant species to be discovered in Japan, a nation where flora has been extensively studied and documented. Nevertheless, Professor SUETSUGU Kenji and his associates recently uncovered a stunning new species of orchid whose rosy pink petals bear a striking resemblance to glasswork (Fig. 1). Since it was initially spotted near Hachijo Island in Tokyo Prefecture, the new species has been given the name Spiranthes hachijoensis. Interestingly, it can be found in familiar environments such as lawns and parks, and even in private gardens and on balconies. This research suggests ...

Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions—as demonstrated by researchers from Tokyo Institute of Technology (Tokyo Tech). The utilization of substitutions shown in this study can be used to develop cyclic peptides with high membrane permeability and oral bioavailability for clinical and therapeutic applications. Interest in cyclic peptides, a class of organic molecules, has reached a new high recently. Their ability as inhibitors has made them ...

Date: 17 March 2023   16 to 18 April in Barcelona, Spain and online   Discover what’s new and on the horizon in the prevention and treatment of heart rhythm disorders at EHRA 2023, a scientific congress of the European Society of Cardiology (ESC).   The annual congress of the European Heart Rhythm Association (EHRA), a branch of the ESC, will be held 16 to 18 April at the Fira Gran Via, Hall 8, in Barcelona, Spain and online. Explore the scientific programme.   Novel research ...

Bacteria are literally everywhere – in oceans, in soils, in extreme environments like hot springs, and even alongside and inside other organisms including humans. They’re nearly invisible, yet they play a big role in almost every facet of life on Earth. Despite their abundance, surprisingly little is known about many microorganisms that have existed for billions of years. This includes an entire lineage of nano-sized bacteria dubbed Omnitrophota. These bacteria, first discovered based on short fragments of DNA just 25 years ago, are common in many environments around the world but have been poorly understood. Until now. An international ...