People from some racial and ethnic groups may face barriers to obtaining obesity medications
2024-12-18
Asians, non-Hispanic Blacks and Hispanics were significantly less likely than whites to use obesity-management medications to lower their weight compared with whites, new research suggests. The differences could not be fully explained by income or education level, health insurance coverage or clinical need.
The study, published in the peer-reviewed Journal of Racial and Ethnic Health Disparities, is one of the few to compare the use of obesity-management medications across racial and ethnic groups, and the first to consider ...
Microplastics in the air may be leading to lung and colon cancers
2024-12-18
A review of 3,000 studies also suggests these minute plastic air particles may be causing male and female infertility.
Tires and degrading garbage shed tiny pieces of plastic into the air, creating a form of air pollution that UC San Francisco researchers suspect may be causing respiratory and other illnesses.
A review of some 3,000 studies implicates these particles in a variety of serious health problems. These include male and female infertility, colon cancer and poor lung function. The particles also may contribute to chronic pulmonary inflammation, ...
Elevated levels of ‘forever chemicals’ found in several smartwatch wrist bands
2024-12-18
Smartwatches and fitness trackers have become ubiquitous forms of wearable tech, accompanying many people throughout their days (and nights). But they may expose the skin to so-called forever chemicals in the process. More expensive wristbands made from fluorinated synthetic rubber revealed particularly high amounts of one forever chemical, perfluorohexanoic acid (PFHxA), according to a study published in ACS’ Environmental Science & Technology Letters.
“This discovery stands out because of the very high concentrations of one type of forever chemical found in items that are in prolonged contact with ...
Potentially harmful bacteria slip through antimicrobial showerheads
2024-12-18
To guard against harmful waterborne pathogens, many consumers, including managers of health-care facilities, install antimicrobial silver-containing showerheads. But in ACS ES&T Water, researchers now report that these fixtures are no “silver bullet.” In real-world showering conditions, most microbes aren’t exposed to the silver long enough to be killed. However, the composition of rare microbes in water from these showerheads varied with each type of fixture tested.
The stream of droplets and fine mist that form during a shower could be inhaled or swallowed. Installing showerheads ...
Children’s Hospital Colorado research transforms the standard of care for childhood cancer
2024-12-18
After participating in a global clinical trial, leaders at the Children’s Hospital Colorado (Children’s Colorado) Center for Cancer and Blood Disorders and the University of Colorado Cancer Center are celebrating results so transformative, they change the standard of care for treating most kids with B-cell acute lymphoblastic leukemia (B-ALL), the most common form of childhood cancer. The new therapy is less toxic than traditional chemotherapy, resulting in significantly fewer side effects like severe infections, mouth sores and bone marrow suppression, ...
Nature’s instructions: How fungi make a key medicinal molecule
2024-12-18
For roughly a century, ever since Alexander Fleming’s accidental discovery of penicillin in 1928, fungi have proven to be a goldmine for medicines. They’ve provided treatments for a wide range of diseases, from infections and high cholesterol to organ rejection and even cancer.
However, the process by which fungi synthesize some of their most potent compounds remains opaque. This is especially true of cyclopentachromone, a key building block in fungal products whose derivatives have shown promise in fighting cancer and reducing inflammation, among other medicinal properties.
Reading Nature’s Instructions
While chemists have made progress in creating ...
Michael Courtney of Turku Bioscience Center receives grant for research on SYNGAP1 missense variants and drug repurposing from SynGAP Research Fund (SRF) dba Cure SYNGAP1
2024-12-18
Mill Valley, CA – December 18, 2024 – The SynGAP Research Fund 501(c)(3) dba Cure SYNGAP1 announced a $108,867 grant to Dr. Michael Courtney and Dr. Li-Li Li at the Turku Bioscience Centre, University of Turku, Finland, to advance their research on SYNGAP1 missense variants. Their project seeks to better understand the functional impact of these mutations and explore drug repurposing as a potential therapeutic approach.
Dr. Courtney’s team will use advanced phenotyping techniques to assess how SYNGAP1 missense variants impact the protein’s ...
Sexism is a risk factor for memory decline among women
2024-12-18
NEW YORK, NY (Dec. 18, 2024)--Women born in the most sexist U.S. states experience faster memory decline in later years compared to women born in the least sexist states, a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.
The difference between being born in the most versus the least sexist state was equivalent to nine years of cognitive aging.
The study is one of a growing number of studies that have investigated links between structural sexism and health. Structural sexism, like structural racism, does not refer to personal incidences but to inequality in resources and power ...
Study supports new blood-based biomarker to detect early brain changes leading to cognitive impairment and dementia
2024-12-18
To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate “downstream” biological markers – those at the end of a cascade of events. But a multicenter study led by UCLA researchers could lead to a cost-effective blood test to identify changes occurring near the top of the chain, potentially identifying at-risk patients at an earlier stage.
“We studied a protein in the blood that is critical in the formation ...
Genetic testing changes course of care in children with neurodevelopmental conditions
2024-12-18
Adding genetic testing to the evaluation of pediatric patients with neurodevelopmental disorders (NDD) resulted in more individualized care, including changes in medication, referrals to clinical trials or specialists, and surveillance for potential medical issues, according to a new UCLA Health study.
Children that present with neurodevelopmental differences, such as autism or global development delay, have high rates of co-occurring neuropsychiatric conditions, and almost half have an underlying genetic diagnosis. The current practice of relying on primary care doctors to refer patients to specialists can create delays in diagnoses and interventions for children ...
ChatGPT errors show it cannot replace finance professionals, yet
2024-12-18
PULLMAN, Wash. – While large language models like ChatGPT can do well when choosing multiple-choice answers on financial licensing exams, they falter when dealing with more nuanced tasks.
A Washington State University-led study analyzed more than 10,000 responses to financial exam questions by the artificial intelligence language models BARD, Llama and ChatGPT.
The researchers asked the models to not only choose answers but also explain the reasoning behind them, then compared those text answers to those by human professionals. ...
Bias in AI amplifies our own biases
2024-12-18
Artificial intelligence (AI) systems tend to take on human biases and amplify them, causing people who use that AI to become more biased themselves, finds a new study by UCL researchers.
Human and AI biases can consequently create a feedback loop, with small initial biases increasing the risk of human error, according to the findings published in Nature Human Behaviour.
The researchers demonstrated that AI bias can have real-world consequences, as they found that people interacting with biased AIs became more likely to underestimate women’s ...
Paris Declaration calls for data-driven forensics to spearhead the fight against fake science
2024-12-18
Supporters of research integrity have signed a new declaration calling for data-driven forensics – known as Forensic Scientometrics (FoSci) – to lead the charge in detecting, exposing and even preventing fake science.
The Forensic Scientometrics (FoSci) Paris Declaration was drafted during an event in Paris last week organized and run by Digital Science’s VP of Research Integrity, Dr Leslie McIntosh. The event was hosted at Institut Universitaire de France (IUF) by Dr Guillaume Cabanac, research integrity “sleuth” and professor at the University of Toulouse, as part of his research chair titled ...
Coral reef nightlife becomes more predatory with artificial light
2024-12-18
Artificial light can wake sleeping fish and attract predators, changing nighttime coral reef communities, according to new research using novel underwater infrared cameras.
The study, published today in Global Change Biology, was conducted by an international team of scientists from the UK, France, French Polynesia and Chile and the first large-scale experiment to investigate the impact of light pollution on the nightlife of coral reefs.
Lead author, Dr Emma Weschke, from the University of Bristol’s School of Biological Sciences, ...
Young exoplanet’s atmosphere unexpectedly differs from its birthplace
2024-12-18
Just as some children physically resemble their parents, many scientists have long thought that developing planets should resemble the swirling disk of gas and dust that births them.
But, in a new study, a Northwestern University-led team of astrophysicists discovered the resemblance might be looser than previously thought. By studying a still-forming exoplanet and its surrounding natal disk, the researchers uncovered a mismatched composition of gases in the planet’s atmosphere compared to gases within the disk.
The surprising finding potentially confirms long-held skepticism that scientists’ current model of planet formation is too simplified.
The ...
Carnivorous squirrels documented in California
2024-12-18
A ground squirrel with cheeks stuffed with nuts, seeds or grains, is a common sight. But a new study provides the first evidence that California ground squirrels also hunt, kill and eat voles. The study, led by the University of Wisconsin-Eau Claire and University of California, Davis, is the first to chronicle widespread carnivorous behavior among squirrels.
Published in the Journal of Ethology, the study fundamentally changes our understanding of ground squirrels. It suggests that what was considered a granivorous species actually is an opportunistic omnivore and more flexible in its diet than was assumed.
The observations occurred in 2024 — the 12th year of the Long-term ...
Researchers develop new test for early osteoarthritis diagnosis
2024-12-18
Diagnosing osteoarthritis often occurs in the late stages when cartilage degradation is severe, making it difficult to distinguish it from other types of arthritis and to determine the best treatment plan. In work published in the Journal of Orthopaedic Research, investigators have developed and tested a new diagnostic test that uses two markers found in the synovial fluid of patients’ joints.
After assessing levels of cartilage oligomeric matrix protein and interleukin‐8, the team came up with an algorithm based on the ratio of these two markers and validated its efficacy in differentiating osteoarthritis from inflammatory arthritis in 171 human knee synovial ...
Research uncovers high extinction risk for many Amazonian tree species
2024-12-18
Among tree species in the Ecuadorian Amazon, investigators at the Universidad de las Américas, in Ecuador, found that 14% are critically endangered and 47% are endangered. The Plants, People, Planet study indicates that trees with smaller fruits face the greatest threats due to declines of specific animal species that disperse them.
The findings reveal that the extinction risk for endemic trees is associated not only with extrinsic factors such as deforestation but also with complex relationships with other living organisms in their environment.
“Thus, our results highlight the importance ...
How did the COVID-19 pandemic and lockdown affect the identity of trans and gender diverse youth?
2024-12-18
Research published in the British Journal of Developmental Psychology indicates that the COVID-19 pandemic and lockdown had largely positive impacts on gender identity development in trans and gender diverse youth.
For the study, 295 transgender and gender diverse U.S. youth, ages 13–22 years, were asked the open-ended question “How has the COVID pandemic changed or affected your own understanding of your gender identity?”
Responses revealed several themes. The most prevalent was “time for identity development,” ...
Does having more chronic conditions increase older adults’ risk of declining kidney function?
2024-12-18
Older adults with multiple chronic conditions may face a high risk of kidney function decline, according to new research published in the Journal of the American Geriatrics Society.
In the study, 3,094 older individuals from the Swedish National Study on Aging and Care in Kungsholmen were followed for 15 years.
There was an independent dose-response relationship between the number of chronic conditions and kidney function decline, so that as the number of chronic conditions increased, kidney function decline became more likely and steeper.
When considering the makeup of conditions rather than just ...
Experts issue new ethical standards for body donation programs
2024-12-18
A new report in the journal Anatomical Sciences Education outlines best practices and standards for human body donation programs across the United States, which accept whole body donations after death for research and education.
The report, issued by a task force of American Association for Anatomy members, seeks to align body donation programs with evolving societal values and legal frameworks. It aims to maintain the highest ethical standards for donors by upholding the principles of informed consent, oversight, and dignity.
The report emphasizes the importance of ensuring potential donors and their families ...
Does an infant breast milk supplement commonly used in Sweden contribute to childhood obesity?
2024-12-18
Many infants in Sweden are given milk cereal drinks, ready-to-mix liquid drink complements to breast milk, after six months of age. New research in Acta Paediatrica found evidence that these products are linked to early rapid weight gain but not to higher anthropometric measures—such as body mass index or waist-to-height ratio—later in childhood.
In the study of 1,333 children from three communities in Western Sweden, physical characteristics and food habits were collected in 2007–2008 family surveys. Follow-up data for 656 children were collected in 2013–2014.
At baseline, 820 (62%) of the 658 boys and 675 girls consumed milk cereal drinks, and 229 (18%) had early ...
Dr. Gerta Hoxhaj named recipient of the Mary Beth Maddox Award and Lectureship for Cancer Research
2024-12-18
TAMEST (Texas Academy of Medicine, Engineering, Science and Technology) has announced Gerta Hoxhaj, Ph.D., Assistant Professor at the Children’s Medical Center Research Institute at UT Southwestern (CRI), as recipient of the 2025 Mary Beth Maddox Award and Lectureship in cancer research. She was chosen for her work in cancer metabolism and revealing new mechanisms crucial for the growth and survival of cancer cells.
The Mary Beth Maddox Award and Lectureship recognizes women scientists in Texas bringing new ideas and innovations to the fight against cancer. It was established in 2022 in honor of Mary Beth Maddox, former ...
Mind’s ear: Investigating the sounds in your head
2024-12-18
Some people can’t imagine a dog barking or a police siren. Songs can’t get stuck in their heads. They have no inner voices.
‘Anauralia’ was proposed in 2021 by scientists from Waipapa Taumata Rau, University of Auckland to describe the little-known condition of a silent mind.
Now, as their investigations into the phenomenon continue, the University will host a global conference on sounds imagined in the mind, an event intended not just for scientists but also philosophers, musicians, poets and writers. ‘Mind’s ...
Robot rehabilitation can offer optimal post-stroke treatment
2024-12-18
The increasing number of strokes and subsequent rehabilitation has highlighted the growing need for effective care strategies. Serious side effects, such as motor paralysis, can be challenging to mend, but the recent incorporation of robots into treatment has shown promise.
Automated robots repeatedly provide the proper movements necessary to recover motor function. However, to ensure appropriate care tailored to the degree of motor paralysis, knowledge of robots and rehabilitation is needed.
Osaka Metropolitan University Professor Takashi Takebayashi of the Graduate School of Rehabilitation Science led a team in collecting data from ...
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