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Can proactive assisted gene flow save Caribbean and Floridian corals?

2025-07-24
In a Policy Forum, Andrew Baker and colleagues discuss the recent regulatory action in Florida that has enabled the world’s first international coral exchange. The exchange was done to bolster genetic diversity in declining elkhorn coral populations, enhancing their resilience to climate change and other environmental pressures. Expanding such efforts to other coral species and regions will require international collaboration and a reevaluation of current conservation laws, note the authors. Coral reefs are among the most climate-sensitive marine ecosystems, with prolonged heat stress causing increasingly frequent and devastating bleaching events. For example, the historic ...

2023 marine heatwaves unprecedented and potentially signal a climate tipping point

2025-07-24
The global marine heatwaves (MHWs) of 2023 were unprecedented in their intensity, persistence, and scale, according to a new study. The findings provide insights into the region-specific drivers of these events, linking them to broader changes in the planet’s climate system. They may also portend an emerging climate tipping point. Marine heatwaves (MHWs) are intense and prolonged episodes of unusually warm ocean temperatures. These events pose severe threats to marine ecosystems, often resulting in widespread coral bleaching and mass mortality events. ...

Researchers document first images of the atomic fingerprint of heat in quantum materials

2025-07-24
College Park, Md. — Researchers investigating atomic-scale phenomena impacting next-generation electronic and quantum devices have captured the first microscopy images of atomic thermal vibrations, revealing a new type of motion that could reshape the design of quantum technologies and ultrathin electronics. Yichao Zhang, an assistant professor in the University of Maryland Department of Materials Science and Engineering, has developed an electron microscopy technique to directly image “moiré phasons”—a physical phenomenon that impacts superconductivity and heat conduction in two-dimensional materials for next-generation ...

Integrating sulfur into crystalline nanostructures fuels catalytic activity

2025-07-24
‘Sulfur enhances reactivity and lowers energy barriers for hydrogen activation’ New active sites containing sulfur significantly outperformed non-sulfur counterparts in hydrogenation catalysis Research supports production of enzyme-like models in stable materials EVANSTON, Ill. --- Despite natural evidence indicating sulfur’s importance and efficiency as a catalyst for critical redox reactions including hydrogenation (addition of hydrogen to molecule) and dehydrogenation (its opposite), chemists have struggled to manage the enzyme’s complexity and fragility at scale. Now, researchers ...

Astronomers discover star-shredding black holes hiding in dusty galaxies

2025-07-24
Astronomers at MIT, Columbia University, and elsewhere have used NASA’s James Webb Space Telescope (JWST) to peer through the dust of nearby galaxies and into the aftermath of a black hole’s stellar feast.  In a study appearing today in Astrophysical Journal Letters, the researchers report that for the first time, JWST has observed several tidal disruption events — instances when a galaxy’s central black hole draws in a nearby star and whips up tidal forces that tear the star to shreds, giving off an enormous burst of energy in the process.  Scientists have observed about 100 ...

Math model sheds light on Alzheimer’s spread

2025-07-24
Mathematics may not be the first thing people associate with Alzheimer’s disease research. But for Pedro Maia, an assistant professor of mathematics and data science at The University of Texas at Arlington, analyzing how different parts of the brain interact like a network is revealing new insights into one of the world’s most devastating brain disorders. Dr. Maia’s latest breakthrough—developed in collaboration with colleagues at the University of California–San Francisco’s Raj Lab—uses advanced mathematical modeling to help explain why Alzheimer’s disease spreads unevenly through the brain. Their work reveals why certain brain regions ...

Older adults with serious illness before surgery use far more health care resources after surgery

2025-07-24
 Key Takeaways Hospital stays, readmissions, emergency department visits, and costs were almost double for older adults with serious illness before elective surgery. Researchers identified four palliative care needs to target before surgery: Pain, depression, functional dependence, and a need for a care partner. Depression was the characteristic most strongly associated with increased health care utilization and costs after surgery. CHICAGO (July 24, 2025) — Older adults who have serious illness before undergoing elective surgery had hospital stays twice as long as similarly aged counterparts; were twice as likely ...

Answer ALS Launches AI drug development collaboration with Tulane, Pennington Biomedical Research Center and GATC Health to advance ALS treatment discovery

2025-07-24
Answer ALS is proud to announce the launch of a groundbreaking collaborative initiative aimed at accelerating AI-powered drug discovery for ALS and other neurodegenerative diseases. This effort, known as the Louisiana AI Drug Development Infrastructure for ALS (LADDIA), brings together leading institutions and innovators, including Tulane University, Pennington Biomedical Research Center, and GATC Health - a tech-bio innovator using validated AI models to accelerate drug discovery from large-scale multiomics data-, to harness the power of artificial intelligence and one of the largest ALS datasets in the world. This ...

Study paves path to improved diagnosis, treatment of NUT carcinoma

2025-07-24
BOSTON, July 24, 2025 – The diagnosis of a suspected lung, head, and neck cancer called NUT carcinoma should include additional testing capable of detecting gene fusions that are definitive markers of the disease, according to a study by Dana-Farber Cancer Institute investigators. The study showed that more than 75 percent of patients with NUT carcinoma may not be immediately diagnosed because standard-of-care DNA testing does not detect NUT carcinoma fusion genes. Tests that can identify gene fusions that are specific to NUT carcinoma include NUT immunohistochemistry (IHC), RNA fusion testing, ...

Scientists discover how correlated disorder boosts superconductivity

2025-07-24
Superconductivity is a unique state of matter in which electric current flows without any energy loss. In materials with defects, it typically emerges at very low temperatures and develops in several stages. An international team of scientists, including physicists from HSE MIEM, has demonstrated that when defects within a material are arranged in a specific pattern rather than randomly, superconductivity can occur at a higher temperature and extend throughout the entire material. This discovery could help develop ...

BASILISK partners with The Planetary Society and CalTech’s IQIM to recruit the global esports audience in the movement to save science

2025-07-24
NEW YORK and SEATTLE – JULY 24, 2025 —  BASILISK, the global esports organization built to champion science, debuted two historic partnerships at the Esports World Cup 2025 in Riyadh, Saudi Arabia this week – furthering its mission to elevate science advocacy through the global reach and cultural influence of competitive gaming. BASILISK’s new strategic partnerships with the California Institute of Technology’s Institute for Quantum Information and Matter (IQIM) and The Planetary Society create a powerful bridge between renowned scientific institutions and the next generation of STEM enthusiasts.  “To root for BASILISK is ...

International study reveals sex and age biases in AI models for skin disease diagnosis

2025-07-24
An international research team led by Assistant Professor Zhiyu Wan from ShanghaiTech University has recently published groundbreaking findings in the journal Health Data Science, highlighting biases in multimodal large language models (LLMs) such as ChatGPT-4 and LLaVA in diagnosing skin diseases from medical images. The study systematically evaluated these AI models across different sex and age groups. Utilizing approximately 10,000 dermatoscopic images, the study focused on three common skin diseases: melanoma, melanocytic nevi, and benign keratosis-like lesions. ...

The evolution of life may have its origins in outer space

2025-07-24
Using the Atacama Large Millimeter/submillimeter Array (ALMA), a team of astronomers led by Abubakar Fadul from the Max Planck Institute for Astronomy (MPIA) has discovered complex organic molecules – including the first tentative detection of ethylene glycol and glycolonitrile – in the protoplanetary disc of the outbursting protostar V883 Orionis. These compounds are considered precursors to the building blocks of life. Comparing different cosmic environments reveals that the abundance and complexity of such molecules increase from star-forming regions to fully evolved planetary systems. This suggests that the seeds of life are assembled in space and are widespread. The ...

Record-breaking ‘gigantic’ deep-sea limpet species named after ONE PIECE character

2025-07-24
Researchers from Japan Agency for Marine-Earth Science and Technology (JAMSTEC) have discovered a deep-sea limpet species 5,922 metres beneath the northwestern Pacific Ocean, marking the deepest known habitat for any true limpet (subclass Patellogastropoda). Described as a new species in the open-access journal Zoosystematics and Evolution, the limpet was found on hard volcanic rock 500 kilometres southeast of Tokyo, Japan. The gastropod measures up to 40.5 mm in shell length, a remarkably large size for a true limpet from ...

When should preventive mastectomy be offered for women at higher risk of breast cancer

2025-07-24
UNDER STRICT EMBARGO UNTIL 4PM (UK TIME) 11 AM (US EASTERN TIME) ON THURSDAY 24 JULY 2025  When should preventive mastectomy be offered for women at higher risk of breast cancer  Peer reviewed | Simulation/ modelling  More women at higher risk of breast cancer should be offered a mastectomy, according to researchers at Queen Mary and London School of Hygiene and Tropical Medicine. A new analysis has found that the surgical technique was a cost-effective way of reducing the likelihood of developing breast cancer compared to breast screening ...

Study compares common type 2 diabetes drugs, finding higher cardiovascular risk for one medication

2025-07-24
New research from investigators at Mass General Brigham suggests that a commonly used type 2 diabetes medication is linked to a higher rate of heart-related conditions compared to medications that hit other targets. The study examined nationwide data from nearly 50,000 patients treated with different sulfonylureas and found that glipizide – the most widely used drug in the U.S. within this category – was linked to higher incidence of heart failure, related hospitalization and death compared to dipeptidyl peptidase-4 (DPP-4) inhibitors. ...

Reshaping tumor neighborhoods to give treatments a boost

2025-07-24
Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions. Cancer cells interact with this neighborhood — which scientists term the tumor microenvironment — in many ways, including obtaining extra resources needed to fuel their unchecked growth. Like a fishing trawler deploying its net, pancreatic ductal adenocarcinoma (PDAC) ...

Racial differences in care quality among men with newly diagnosed prostate cancer

2025-07-24
About The Study: Among men with traditional Medicare, this study examined racial differences in 2 important measures of prostate cancer care quality that have contrasting relationships with utilization. Black men had lower odds of confirmatory testing among those on active surveillance, where utilization and quality are tightly aligned, indicating worse care. Conversely, Black men had lower odds of overtreatment, where utilization and quality are misaligned, suggesting better care in this dimension.  Corresponding Author: To contact the corresponding author, Arnav Srivastava, MD, MPH, MS, email srivasar@med.umich.edu. To access ...

Defining lifetime risk thresholds for breast cancer surgical prevention

2025-07-24
About The Study: In this economic evaluation, undergoing risk-reducing mastectomy (RRM) appears cost-effective for women ages 30 to 55 with a lifetime breast cancer risk of 35% or higher. These results could have significant clinical implications to expand access to RRM beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers. Future studies evaluating the acceptability, uptake, and long-term outcomes of RRM among these women are warranted. Corresponding Author: To contact the corresponding author, Ranjit Manchanda, MD, PhD, email r.manchanda@qmul.ac.uk. To access the embargoed study: Visit our For The ...

Study finds large language models (LLMs) use stigmatizing language about individuals with alcohol and substance use disorders

2025-07-24
As artificial intelligence is rapidly developing and becoming a growing presence in healthcare communication, a new study addresses a concern that large language models (LLMs) can reinforce harmful stereotypes by using stigmatizing language. The study from researchers at Mass General Brigham found that more than 35% of responses in answers related to alcohol- and substance use-related conditions contained stigmatizing language. But the researchers also highlight that targeted prompts can be used to substantially reduce stigmatizing language in the LLMs’ answers. Results are published in The Journal of Addiction Medicine. “Using patient-centered language can build ...

New study in Ukraine indicates significant lifetime exposure and ongoing transmission of hepatitis B and C viruses among the general population

2025-07-24
A study just published on Eurosurveillance has found evidence of substantial lifetime exposure to hepatitis B and C viruses in Ukraine in a 2021 nationwide, representative sample of the population, with findings also suggesting significant ongoing circulation of these viruses. Ahead of World Hepatitis Day 2025, viral hepatitis remains a major global health concern, and is one of the priority infectious diseases under the United Nations’ Sustainable Development Goal 3. [1][2] The World Health Organization (WHO) Global Hepatitis ...

K-biofoundry develops international standard language to unite synthetic biology laboratories worldwide

2025-07-24
The National Biofoundry Project Team at the Korea Research Institute of Bioscience and Biotechnology (KRIBB), led by Dr. Haseong Kim, has spearheaded an international joint research effort (including institutions from Korea, the U.S., the U.K., Singapore, and others—10 in total) to create a new standard framework that simplifies and enhances the accuracy and efficiency of synthetic biology research. This framework is anticipated to serve as an international standard for biofoundries—automated laboratories in synthetic biology. Driven by advancements in deep-tech fields such as synthetic biology ...

Reliance on administrative billing codes to track medical conditions can lead to high diagnostic error rates

2025-07-24
Use of billing codes in big data sets to find diagnoses can result in up to two-thirds of cases being mistakenly identified, new UCLA-led research finds. Databases frequently used for medical research such as those for the Centers for Medicare & Medicaid Services or the National Inpatient Survey typically rely on ambulatory billing codes to identify diseases or medical procedures, but their accuracy is rarely verified in publications that rely on this data, the researchers write in a report published in the peer-reviewed journal ...

Most hospital visits of impaired, terminal nursing home residents are avoidable

2025-07-24
Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals. These unnecessary transfers not only cause distress and discomfort for residents and families but also lead to hospital-acquired complications and added costs for the health care system. In the United States, hospital transfers from nursing homes significantly ...

Assessing spontaneous behavioral changes in a mouse model of schizophrenia

2025-07-24
Schizophrenia is a serious mental health condition that affects thoughts, moods, perceptions, and behaviors. Affected individuals experience positive symptoms like delusions and hallucinations, and negative symptoms like social withdrawal, cognitive deficits, disorganized thoughts and speech, and a decreased experience of pleasure. While schizophrenia is caused by a complex interplay of genetic, environmental, and lifestyle factors, precise mechanisms remain elusive. Animal models provide valuable insights into the neurobiological mechanisms that underpin schizophrenia. However, conventional behavioral assessments ...
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