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Could living near water mean you’ll live longer?

2025-07-28
COLUMBUS, Ohio – Living within miles of the ocean breeze may be linked to a longer life, but you shouldn’t count on the same benefits if you live in a riverside city, suggests a recent study. Researchers from The Ohio State University analyzed population data — including life expectancy — in more than 66,000 census tracts throughout the U.S. and compared it based on proximity to waterways. Their study was published online in the journal Environmental Research. A correlation between longer life expectancy and water was clear for those who live within about 30 miles of an ocean or gulf. But for those who live in urban settings and near an inland ...

Alcohol withdrawal syndrome linked to worse surgical outcomes, higher costs

2025-07-28
Key Takeaways Among 3 million surgical patients, 0.5% developed alcohol withdrawal syndrome (AWS), with 0.2% experiencing severe delirium tremens (DT).  AWS was associated with a 37% higher risk of complications, including respiratory failure and sepsis, and a 40% increased mortality risk if DT occurred. Hospital stays were 5 days longer, and costs rose by $10,000 per patient with AWS, totaling $165 million in excess costs nationwide.  CHICAGO — Patients who develop alcohol withdrawal syndrome (AWS) after major surgery face significantly higher risks of complications, longer hospital stays, and increased health care costs, ...

US POINTER trial: Structured lifestyle intervention delays cognitive decline

2025-07-28
About The Study: This randomized clinical trial found that among older adults at risk of cognitive decline and dementia, a structured, higher-intensity intervention of regular moderate-to-high-intensity physical exercise, adherence to the MIND diet, cognitive challenge and social engagement, and cardiovascular health monitoring had a statistically significant greater benefit on global cognition compared with an unstructured, self-guided intervention. Known as the US Study to Protect Brain Health Through Lifestyle ...

Detecting a potential behavioral biomarker for Parkinson’s disease in mice

2025-07-28
Detecting early rising Parkinson’s disease (PD) symptoms could improve treatment outcomes by enabling earlier treatment interventions. In a new eNeuro paper, Daniil Berezhnoi, from Georgetown University, and colleagues used machine learning technology to detect subtle, early rising behavioral changes in mouse models of PD. The researchers also evaluated whether Levodopa, the primary approved treatment for PD, can effectively treat these symptoms.  Berezhnoi et al. used a previously developed motion sequencing platform to evaluate movements of different ...

Expectations about pain influence the experience in different ways

2025-07-28
Previous expectations can influence how much pain people eventually feel. These expectations can be shaped by external cues or by verbal information from clinicians about how treatments might relieve pain. Led by Lauren Atlas, researchers from the National Institute of Health explored if and how distinct ways of shaping expectations differentially influence physically hurtful experiences.  In their JNeurosci paper, the researchers present their findings from 40 healthy volunteers who rated how hurt they were following painful ...

Landmark sleep study links objective sleep patterns with 172 diseases—regularity matters more than duration

2025-07-28
A groundbreaking international study, recently published in Health Data Science, analyzed objective sleep data from 88,461 adults in the UK Biobank and found significant associations between sleep traits and 172 diseases. The research, led by teams from Peking University and Army Medical University, highlights sleep regularity—such as bedtime consistency and circadian rhythm stability—as an underrecognized but critical factor in disease risk. Using actigraphy data over an average of 6.8 years, researchers identified that 92 diseases had over 20% of their risk attributable to poor sleep behavior. Notably, irregular ...

Breaking research at ADLM 2025: AI poised to revolutionize Lyme disease testing, treatment

2025-07-28
CHICAGO — Today at ADLM 2025 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), researchers will unveil a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard — and that could translate to vastly improved patient outcomes. A second study highlights how certain generative AI tools can empower adolescents by helping them to gather useful medical information. Together, these findings spotlight the potential of AI to make a profound, positive difference in people’s ...

CD4+ T cell-mediated immune drift in biologic treatment of inflammatory skin diseases

2025-07-28
Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4). Biologics targeting specific pathways—TNF-α, IL-17, IL-12/23, IL-4/13, PD-1/PD-L1—revolutionize treatment but trigger immune drift, shifting CD4+ T-cell polarization and causing adverse skin reactions. This review synthesizes mechanisms, clinical manifestations, and management strategies. Mechanisms of Immune Drift by Biologic Class (Summarized in Table 1) 1. TNF-α Inhibitors (Etanercept, Infliximab, Adalimumab) Mechanism: Blocking ...

Spotlight on technology to protect older Australians from respiratory infections

2025-07-28
Simple technology that harnesses ultraviolet light to ‘zap’ airborne viruses has been shown to significantly lower the number of respiratory infections in aged care facilities, paving the way for smarter infection control. Adapted by scientists from Flinders Health and Medical Research Institute  (FHMRI) and SAHMRI, the technology is based on using germicidal ultraviolet (GUV) appliances which purify the air with UV-C light rays and deactivate harmful micro-organisms like viruses and bacteria. The new study published in JAMA Internal Medicine trialled commercially-available GUV appliances in aged care facilities ...

There’s something in the air

2025-07-28
Researchers at the University of Tokyo explored how female body odor can influence behaviors in men. They found certain scent compounds in female body odor increased during ovulation and can subtly influence how men feel. When these scents were added to armpit odor samples, men rated them as more pleasant and faces associated with the samples as more attractive. The scents also seemed to reduce stress. The team states this is not evidence of pheromones in humans, but that smell might subtly shape how we people interact. While they’re a common staple of pop culture, especially in romantic comedies, pheromones, behavior-altering ...

New insights could help phages defeat antibiotic resistant bacteria

2025-07-28
UNDER EMBARGO UNTIL 16:00 UK TIME (11:00 AM ET) ON MONDAY 28 JULY 2025 New insights could help phages defeat antibiotic resistant bacteria Researchers at the University of Southampton have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance. Phages are seen as a promising alternative treatment to antibiotics. Unpicking how bacteria protect themselves, and how phages might overcome these defences, could be a significant step in defeating antibiotic resistant bacteria. Phages, ...

New system dramatically speeds the search for polymer materials

2025-07-28
Cambridge, MA – Scientists often seek new materials derived from polymers. Rather than starting a polymer search from scratch, they save time and money by blending existing polymers to achieve desired properties. But identifying the best blend is a thorny problem. Not only is there a practically limitless number of potential combinations, but polymers interact in complex ways, so the properties of a new blend are challenging to predict. To accelerate the discovery of new materials, MIT researchers ...

Safety of JN.1-updated mRNA COVID-19 vaccines

2025-07-28
About The Study: In this nationwide cohort study, no increased risk of 29 adverse events was observed after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage in approximately 1 million adults.  Corresponding Author: To contact the corresponding author, Niklas Worm Andersson, MD, PhD, email nian@ssi.dk. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.23557) Editor’s Note: Please see the article for additional information, ...

Type 2 diabetes and financial outcomes

2025-07-28
About The Study: The findings of this study suggest that patients with type 2 diabetes may experience substantially more adverse financial outcomes compared with patients without diabetes, highlighting the need to consider patient financial health when treating type 2 diabetes, particularly for patient groups at higher risk.  Corresponding Author: To contact the corresponding author, Cazilia Loibl, PhD, CFP, email loibl.3@osu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.23453) Editor’s ...

A financial toll on patients with type 2 diabetes

2025-07-28
Embargoed until 11 a.m. ET, July 28, 2025   In a first-of-its-kind study, researchers used a unique dataset to show that patients with type 2 diabetes have significantly worse financial outcomes than other patients.   Findings showed diabetes patients fared worse on all seven financial outcomes studied, including below-prime credit scores, medical and non-medical debt in collections, 60-plus-day delinquent debt, debt charge-offs, bankruptcy filings and foreclosure.   The diabetes patients in this study were compared to people who had a blood test ...

Safflower yellow pigments in coronary heart disease: Mechanisms, applications, and future perspectives

2025-07-28
Coronary heart disease (CHD), characterized by atherosclerosis-induced myocardial ischemia, remains a leading cause of mortality in China. Safflower yellow pigments (SYPs), the primary bioactive components of Carthamus tinctorius L., consist mainly of quinochalcone C-glycosides, with hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) as key constituents. This review synthesizes evidence on SYPs' mechanisms, therapeutic applications, and future directions in CHD management. Chemical Composition and Pharmacokinetics SYPs comprise over 20 identified compounds, including HSYA and AHSYB, which confer cardiovascular protection, anti-inflammatory, and antioxidant activities. ...

TraMA: new RNA-based measure predicts mortality risk and tracks aging

2025-07-28
“TraMA is likely to be of particular value to researchers interested in understanding the biological processes underlying health and aging, and for social, psychological, epidemiological, and demographic studies of health and aging.” BUFFALO, NY — July 28, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled “Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA).” In ...

From WebMD to AI chatbots: How innovation has empowered patients to take control of their health

2025-07-28
TORONTO, ON July 28, 2025 A new research article published in the Journal of Participatory Medicine unveils how successive waves of digital technology innovation have empowered patients, fostering a more collaborative and responsive health care system. The paper, titled "From Internet to Artificial Intelligence (Al) Bots: Symbiotic Evolutions of Digital Technologies and e-Patients," explores the symbiotic evolution of digital health tools and the increasingly engaged e-patient. The concept of the e-patient, defined as an individual "equipped, enabled, empowered, and engaged" in their health, has been propelled forward by advancements spanning ...

Unravelling antileishmanial mechanisms of phytochemicals: From mitochondrial disruption to immunomodulation

2025-07-28
Leishmaniasis, a neglected tropical disease caused by Leishmania parasites, affects millions globally. Current synthetic treatments face limitations including toxicity, cost, and resistance. Phytochemicals from medicinal plants offer promising alternatives. This mini-review synthesizes preclinical mechanisms of plant-derived compounds against leishmaniasis, focusing on mitochondrial disruption, immunomodulation, and redox imbalance. Key Antileishmanial Mechanisms 1. Membrane Disruption & ...

Association for Molecular Pathology announces 2025 award recipients

2025-07-28
The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today announced the recipients of its 2025 Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership and Meritorious Service Awards. These prestigious honors will be presented in November during the AMP 2025 Annual Meeting & Expo in Boston. Award for Excellence in Molecular Diagnostics Elaine R. Mardis, Ph.D. Co-executive Director, Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children’s Hospital Rasmussen Nationwide Foundation Endowed Chair in Genomic ...

When light collides with light

2025-07-28
Usually, light waves can pass through each other without any resistance. According to the laws of electrodynamics, two light beams can exist in the same place without influencing each other; they simply overlap. Light saber battles, as seen in science fiction films, would therefore be rather boring in reality. Nevertheless, quantum physics predicts the effect of “light-on-light scattering”. Ordinary lasers are not powerful enough to detect it, but it has been observed at the CERN particle accelerator. Virtual particles can literally emerge from nothing for a short time, interact with the photons and change their direction. The effect is extremely small, ...

Study finds that white students visit college advisers the least, but benefit most in terms of graduation rates and GPA

2025-07-28
A new study finds that White students visit academic advisers the least, but have the highest academic benefits, in terms of GPA and graduation rates, compared to nonwhite students and international students. In higher education, substantial gaps exist between White and nonwhite students, with a greater number of White students graduating in fewer years and receiving higher grades than many other groups. Prior research shows that nonwhite students are less likely to engage with faculty members, but there is a dearth of information related to interactions with academic advisers—staffers ...

Science by the millions: How everyday people are revolutionizing global biodiversity research with tech

2025-07-28
A frog croaks from a walking trail. A hiker snaps a photo and uploads it to iNaturalist. That single act — one person, one amphibian and one click — feeds into a growing global dataset that scientists now use to map shifting species ranges, detect invasive threats and even discover new species. An international study led by researchers at the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) shows how iNaturalist, the global technology platform through which everyday people share ...

A bolt is born! Atmospheric events underpinning lightning strikes explained

2025-07-28
UNIVERSITY PARK, Pa. — Though scientists have long understood how lightning strikes, the precise atmospheric events that trigger it within thunderclouds remained a perplexing mystery. The mystery may be solved, thanks to a team of researchers led by Victor Pasko, professor of electrical engineering in the Penn State School of Electrical Engineering and Computer Science, that has revealed the powerful chain reaction that triggers lightning. In the study published today (July 28) in the Journal ...

Using alcohol to reduce the costs of industrial water electrolysis

2025-07-28
Hybrid water electrolysis (HWE) is an emerging field that aims to overcome some of the limitations of conventional water electrolysis (CWE) for the production of green hydrogen. In CWE, two reactions take place at each of the electrodes (anode and cathode): one reaction produces hydrogen at the cathode (the hydrogen evolution reaction) and the other produces oxygen at the anode (the oxygen evolution reaction, OER). The concept of hybrid water electrolysis revolves around replacing the anode reaction of CWE (the OER), which is inefficient and requires ...
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