If you build it, will they come? Wildlife corridors need smarter design
2024-09-18
As human population and development continue to expand, it’s more important than ever to set aside corridors of undeveloped land where wildlife can travel safely, helping to ensure their long-term survival. However, a recent study by the University of Maryland reveals that current methods of designing and evaluating wildlife corridors may not be adequate to ensure wildlife protection, and suggests that Best Management Practices should include analyzing corridors with a smarter and more thorough framework. University researchers tested different ...
Sea surface temperature record in the southwestern Pacific: Coral colony from Fiji reveals warmest temperatures in over 600 years
2024-09-18
The sea surface temperature in the Fijian archipelago in the southwestern Pacific is now at its maximum for more than 600 years. This is the result of an international research team's evaluation of a new coral record providing further evidence for unprecedented warming in the western Pacific Ocean. According to this, the year 2022 was the warmest year in the region since 1370. The scientists used the giant coral Diploastrea heliopora colony in Fiji to obtain the data for the new reconstruction. These unique and long-lived massive corals record long-term climatic and ...
Homemade ‘play-putty’ can read the body’s electric signals, find UMass researchers
2024-09-18
AMHERST, Mass. – A new study by University of Massachusetts Amherst researchers demonstrates the effectiveness of homemade play putty at reading brain, heart, muscle and eye activity. Published in Device, the research outlines the conductive properties of this material, so-named “squishy circuits.”
“[Squishy circuits] are literally child’s play putty, that is also conductive” describes Dmitry Kireev, assistant professor of biomedical engineering and senior author on the paper.
The conductive squishy ...
Magnifying deep space through the “carousel lens”
2024-09-18
In a rare and extraordinary discovery, researchers have identified a unique configuration of galaxies that form the most exquisitely aligned gravitational lens found to date. The Carousel Lens is a massive cluster-scale gravitational lens system that will enable researchers to delve deeper into the mysteries of the cosmos, including dark matter and dark energy.
“This is an amazingly lucky ‘galactic line-up’ – a chance alignment of multiple galaxies across a line-of-sight spanning most of the observable universe,” said David Schlegel, a co-author of the study and a senior scientist in Berkeley Lab’s Physics Division. "Finding one such alignment is ...
Another new wasp species discovered by researchers Rice campus
2024-09-18
A newly identified wasp species, Chrysonotomyia susbelli, has been discovered in Houston, Texas, marking the 18th new species identified by Rice University’s Scott Egan and his research team since 2014. The discovery, the fourth wasp species found on the university grounds in seven years, reveals the hidden world of parasitoid wasps and the intricate ecosystems that thrive outside our doors.
The Chrysonotomyia susbelli is a parasitoid wasp, about 1 millimeter long, that emerges from galls, or tumorlike growths created by the gall wasp Neuroterus bussae found on southern live oak leaves. The galls serve as microhabitats within which larvae feed, develop and pupate. ...
Greenhouse gains: cucumbers get a genetic upgrade through innovative pollen tech
2024-09-18
Researchers have achieved a groundbreaking advancement in plant biotechnology by using a magnetofected pollen gene delivery system to genetically transform cucumbers. This cutting-edge method uses DNA-coated magnetic nanoparticles to introduce foreign genes into pollen, producing genetically modified seeds without the need for traditional tissue culture or regeneration steps. This technique significantly streamlines and accelerates crop genetic modification, opening up new avenues to boost agricultural productivity and resilience.
Genetic modification in horticultural crops, particularly within the Cucurbitaceae family, is often hindered by complex tissue culture requirements and ...
Like humans, artificial minds can learn by thinking
2024-09-18
Some of the greatest discoveries don’t come merely from observations but from thinking. Einstein developed theories about relativity through thought experiments, and Galileo derived insights about gravity through mental simulations. A review published September 18 in the journal Trends in Cognitive Sciences shows that this process of thinking is not exclusive to humans. Artificial intelligence, too, is capable of self-correction and arriving at new conclusions through “learning by thinking.”
“There are some recent demonstrations of what looks like learning by thinking in AI, ...
Discarding the placenta after birth leads to loss of valuable information, pathologists say
2024-09-18
In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention.
“Placentas should not be considered a waste tissue,” says senior author Mana Parast, MD, PhD, professor of pathology at University of California San Diego School of Medicine. ...
Nonfatal opioid overdoses in youth spiked during pandemic
2024-09-18
Drug overdose mortality has risen faster among adolescents than the general population in recent years, largely due to fentanyl, a potent opioid pain medication. A new study published in JAMA sheds light on trends in nonfatal opioid overdoses in youth – an area that was not as well characterized, but key to formulating prevention strategies to save lives.
Researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues analyzed data using Emergency Medical Services (EMS) encounters from January 2018 to December 2022. They found that opioid overdoses in youth increased at pandemic onset and remained elevated compared to pre-pandemic levels. The majority ...
Characteristics and trends of prehospital encounters for opioid overdoses among US youth, 2018-2022
2024-09-18
About The Study: Prehospital encounters for youth opioid overdoses were increasing prior to the pandemic, increased with the onset, and then stabilized, remaining higher than pre-pandemic levels. Although overall patterns were largely driven by those ages 18 through 24, adolescents ages 12 through 17 were the only subgroup with an increasing number of encounters both before and during the pandemic.
Corresponding Author: To contact the corresponding author, Jamie Lim, MD, email jlim@luriechildrens.org.
To access the embargoed study: Visit our ...
Gargantuan black hole jets are biggest seen yet
2024-09-18
** Caltech is hosting an embargoed media zoom about this result on Monday, September 16 at 10am Pacific/1pm Eastern. You can register here:
https://caltech.zoom.us/webinar/register/WN_gYEV5Tl1S0uZkZG1gDIEnQ#/registration
Astronomers have spotted the biggest pair of black hole jets ever seen, spanning 23 million light-years in total length. That's equivalent to lining up 140 Milky Way galaxies back to back.
"This pair is not just the size of a solar system, or a Milky Way; we are talking about 140 Milky Way diameters in total," says Martijn ...
An update on the survival of the first 50 face transplants worldwide
2024-09-18
About The Study: In this study, the overall survival of the face transplants is encouraging. These data suggest that the acceptable long-term survival of face transplants makes them a reconstructive option for extensive facial defects.
Quote from corresponding author Pauliina Homsy, MD, PhD:
“A total of 50 face transplants have been performed since 2005. Activity has been concentrated with only 18 centers in 11 countries giving this treatment. Our study demonstrates an overall 5- and 10-year survival of face transplants ...
Social determinants of health and insurance claim denials for preventive care
2024-09-18
About The Study: In this cohort study of 1.5 million patients seeking preventive care, denials of insurance claims for preventive care were disproportionately more common among at-risk patient populations. This administrative burden potentially perpetuates inequitable access to high-value health care.
Corresponding Author: To contact the corresponding author, Alex Hoagland, PhD, email alexander.hoagland@utoronto.ca.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.33316)
Editor’s ...
Patient self-guided interventions to reduce sedative use and improve sleep
2024-09-18
About The Study: The results of this randomized clinical trial showed that transitioning insomnia care for older adults away from long-term sedative use and toward cognitive behavioral therapy for insomnia can be achieved using a mailed, direct-to-patient approach.
Corresponding Author: To contact the corresponding author, David M. Gardner, PharmD, MSc CH&E, email david.gardner@dal.ca.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(10.1001/jamapsychiatry.2024.2731)
Editor’s ...
Brigham researchers use machine learning to improve cardiovascular risk assessment
2024-09-18
Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability. Investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, used advanced machine learning to increase the accuracy of a national cardiovascular risk calculator while preserving its interpretability and original risk associations. Their results showed higher accuracy overall in an electronic health records cohort ...
How Ukraine can rebuild its energy system
2024-09-18
One of the main targets of Russia’s ongoing attacks on Ukraine is the energy infrastructure. The extent of the destruction is enormous. “One year after the start of the war in February 2022, 76 percent of thermal power plants had been destroyed; now the figure is 95 percent,” says Ukrainian scientist Iryna Doronina. “And all the large hydroelectric power plants have also failed.” The breaching of the Kakhovka dam proved to be particularly devastating. The huge outflow of water – the reservoir ...
Research points a way to modulate scarring in spinal cord injury
2024-09-18
Media Contact: laura.kurtzman@ucsf.edu, (415) 502-6397
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After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves from regenerating, impeding the healing process and leading to permanent nerve damage, loss of sensation or paralysis.
Now, UC San Francisco researchers have discovered how a rarely studied cell type controls the formation of scar tissue in spinal cord injuries. Activating ...
Breast and ovarian cancer newly linked to thousands of gene variants
2024-09-18
Scientists have pinpointed thousands of genetic changes in a gene that may increase a person’s risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.
Researchers from the Wellcome Sanger Institute and their collaborators focused on the ‘cancer protection’ gene RAD51C, finding over 3,000 harmful genetic changes that could potentially disrupt its function and increase ovarian cancer risk six-fold and risk of aggressive subtypes of breast ...
Metal exposure can increase cardiovascular disease risk
2024-09-18
Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors like smoking and diabetes, according to a study published today in JACC, the flagship journal of the American College of Cardiology. The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis.
"Our findings highlight the importance ...
Penny for your thoughts? Master copper regulator discovery may offer Alzheimer’s clues
2024-09-18
New therapeutic opportunities often emerge from research on simple organisms. For instance, the 2020 Nobel Prize in Chemistry awarded to Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., for their CRISPR-based DNA editing discovery began with studies using bacteria just a decade prior. Today, CRISPR therapies are approved for several disorders, and more such treatments are in the offing.
Recognizing the translational potential of studies in simpler animal models, a team of scientists led by Randy D. Blakely, ...
Keck Hospital of USC named a 2024 top performer by Vizient, Inc.
2024-09-18
LOS ANGELES — Keck Hospital of USC has been named a top performer in the 2024 Bernard A. Birnbaum, MD, Quality Leadership award by Vizient, Inc., a leading health care performance improvement company.
The top performer designation acknowledges the hospital’s excellence in delivering high-quality care as measured by the annual Vizient Quality and Accountability Study.
Keck Hospital was among 14 top performers out of 115 comprehensive academic medical centers nationally and achieved a five-star ...
NSF and Simons Foundation launch 2 AI Institutes to help astronomers understand the cosmos
2024-09-18
Note: Embargoed until 8:00 a.m. ET on Sept. 18, 2024
From the early telescopes made hundreds of years ago by Galileo to the sophisticated astronomical observatories of today, people have built increasingly innovative tools to probe and measure the cosmos. Soon, researchers at two new institutes funded by the U.S. National Science Foundation and the Simons Foundation will build a new breed of astronomical tools by harnessing the uniquely powerful abilities of artificial intelligence to assist and accelerate humanity's understanding of the universe.
The new National Artificial Intelligence ...
Exploring the effect of low sodium concentrations on brain microglial cells
2024-09-18
Low serum sodium concentrations in blood are called hyponatremia, a prevalent clinical electrolyte disorder. In contrast to acute hyponatremia, chronic hyponatremia has been previously considered asymptomatic because the brain can successfully adapt to hyponatremia. If not treated, chronic hyponatremia can lead to complications such as fractures, falls, memory impairment, and other mental issues. Treating the chronic condition is, however, quite tricky as it has been observed that overly rapid correction of hyponatremia ...
New Alzheimer’s studies reveal disease biology, risk for progression, and the potential for a novel blood test
2024-09-18
EMBARGOED by Alzheimer’s & Dementia until 7 a.m., ET, Sept. 18, 2024
Contact: Gina DiGravio, Boston University, 617-358-7838, ginad@bu.edu
Contact: Andrea Zeek, IU School of Medicine, 317-671-3114, anzeek@iu.edu
(Boston)— The failure to diagnose Alzheimer’s disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer’s disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid (“A”) and tau (“T”), ...
Comorbidity and disease activity in multiple sclerosis
2024-09-18
About The Study: In this study, a higher burden of comorbidity was associated with worse clinical outcomes in people with multiple sclerosis (MS), although comorbidity could potentially be a partial mediator of other negative prognostic factors. The findings suggest a substantial adverse association of the comorbidities investigated with MS disease activity and that prevention and management of comorbidities should be a pressing concern in clinical practice.
Corresponding Author: To contact the corresponding author, Amber Salter, PhD, email amber.salter@utsouthwestern.edu.
To access the embargoed study: Visit our For The Media website at this ...
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