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New evidence links tire chemicals to chronic liver and brain toxicity

2025-05-19
Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product     6PPD-quinone (6PPDQ)—are raising new red flags for aquatic ecosystems. A recent study reveals that prolonged exposure to these chemicals at environmentally realistic levels disrupts lipid and carbohydrate metabolism, causes liver injury, and alters behavioral patterns in zebrafish. The research shows that 6PPD primarily accumulates in the liver, while 6PPDQ targets the brain. Both compounds downregulate PPARγ, a key regulator of metabolic function, and elevate pro-inflammatory cytokines, triggering chronic ...

Two new studies in American Journal of Psychiatry explore risk prediction for postpartum mental health conditions

2025-05-19
LOS ANGELES, May 19, 2025 — Two new studies examining mental health risks postpartum were published online today in the American Journal of Psychiatry in conjunction with Maternal Mental Health Awareness Month and the 2025 Annual Meeting of the American Psychiatric Association (APA). One study sought to estimate the risk of postpartum depression in people without a history of depression, and the other looked at the familial contribution to the risk of postpartum psychosis. Researchers from both studies were on hand to discuss their findings at a special briefing held at the APA meeting.   Risk for Postpartum Depression Postpartum ...

Fitness fight: Native bees struggle against invasive honey bee

2025-05-19
New Curtin University research has revealed that high densities of European honey bees could be harming Australian native bees’ ‘fitness’ by reducing their reproductive success and altering key traits linked to survival. The study, led by Adjunct Research Fellow Dr Kit Prendergast from Curtin’s School of Molecular and Life Sciences, found that honey bees not only dominate pollen resources but may also affect the fitness of native cavity-nesting bees – with concerning consequences for biodiversity. Dr Prendergast said the study used specially designed wooden ‘bee ...

‘Every single species is a unique product of evolution, like a work of art’: how Dr Kit Prendergast champions bees and biodiversity

2025-05-19
What inspired you to become a researcher?   I’ve always had a passion for nature and biodiversity, ever since I was a child (David Attenborough was, and still is, an inspiration). After completing my Honors project on horse behavior and publishing a review on the role of digging mammals in Australian ecosystems, when it came to conducting my PhD, I knew I wanted to do something that would make a real difference to conserving biodiversity.  I love research – unlike many people, I loved to study at university. I always knew I wanted to become a scientist, to advance our knowledge about biodiversity and further ...

Capuchin monkeys develop bizarre “fad” of abducting baby howlers

2025-05-19
On an island off the coast of Panama lives a population of wild primates with a remarkable culture. White-faced capuchins on Jicarón Island in Coiba National Park use stone tools; and scientists have been monitoring this unique tradition with an array of motion-triggered cameras on the island since 2017. In 2022, doctoral researcher Zoë Goldsborough was looking through the camera trap footage when she found an unusual sighting, something they had never seen in the previous five years of data: a capuchin monkey ...

Antibiotic treatment in patients hospitalized for nonsevere COVID-19

2025-05-19
About The Study: In this large cohort study of patients hospitalized with nonsevere COVID-19, there was no clinically meaningful difference in outcomes with early antibiotic treatment. Given the risks associated with unnecessary antibiotic treatment, these results argue against routine antibiotic use in this population. Corresponding author: To contact the corresponding author, Michael S. Pulia, M.D., Ph.D., email mspulia@medicine.wisc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi: 10.1001/jamanetworkopen.2025.11499) Editor’s ...

Mental health trajectories among US survivors of adolescent and young adult cancer

2025-05-19
About The Study: In this cohort study, survivors of adolescence and young adulthood cancer reported significantly worse mental health trajectories into middle or older adulthood, compared with individuals who experienced cancer as adults or never had it. Cancer clinicians should recognize the mental health burden for this population into middle age and older adulthood. Corresponding author: To contact the corresponding author, Anao Zhang, Ph.D., email zhangan@med.umich.edu. To access the embargoed study: Visit our ...

Mice use chemical cues such as odours to sense social hierarchy

2025-05-19
Researchers at the Francis Crick Institute have shown that mice use chemical cues, including odours, to detect the social rank of an unfamiliar mouse and compare it to their own, using this information to determine their behaviour. Like many mammals, mice live in a social hierarchy where some are more dominant than others. This helps to avoid conflict and establish breeding partners. It has been suggested previously that some mice might display fixed behaviour regardless of who they are interacting with, or that physical properties can give cues about social ranking. However, new research published ...

Experimental painkiller could outsmart opioids – without the high  

2025-05-19
An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids. The drug, called SBI-810, is part of a new generation of compounds designed to target a receptor on the nerves and spinal cord. While opioids flood multiple cellular pathways indiscriminately, SBI-810, a non-opioid treatment, takes a more focused approach, activating only a specific pain-relief pathway that avoids the euphoric “high” linked ...

AI chip developed for decentralized use without the cloud

2025-05-19
A new AI chip developed at the Technical University of Munich (TUM) works without the cloud server or internet connections needed by existing chips. The AI Pro, designed by Prof Hussam Amrouch, is modelled on the human brain. Its innovative neuromorphic architecture enables it to perform calculations on the spot, ensuring full cyber security. It is also up to ten times more energy efficient. The professor of AI processor design at TUM has already had the first prototypes produced by semiconductor manufacturer Global Foundries in Dresden. Unlike conventional chips, the ...

Florida Inventors Hall of Fame announces 2025 inductees: Celebrating the visionaries behind the breakthroughs

2025-05-19
*** Embargoed for public release until Monday, May 19, 2025 at 11 a.m. ET *** TAMPA, Fla. (May 19, 2025) – The Florida Inventors Hall of Fame is proud to announce its 2025 inductees -- 10 pioneering inventors whose groundbreaking contributions span disciplines ranging from nanotechnology and regenerative medicine to energy systems and video technologies. Their work has established and reshaped entire fields, propelled scientific progress and exemplified the spirit of innovation that defines Florida’s growing ecosystem of discovery and enterprise. "The 2025 Inductees ...

Level-ground and stair adaptation for hip exoskeletons based on continuous locomotion mode perception

2025-05-19
A research article published by the Peking University presented a control framework for exoskeletons based on environmental perception, which effectively integrates environmental information and human kinematic data, improves the accuracy and lead time of transition detection, thereby enhancing smooth switching of control strategies across different terrains. Additionally, the adoption of a learning-free method eliminates the need for data collection and model training, demonstrating strong generalization capabilities across users. The new research paper, published on Apr. 22 in the journal Cyborg and Bionic ...

Helping noisy data centers fit into residential neighborhoods #ASA188

2025-05-19
NEW ORLEANS, May 19, 2025 – The past few years have seen an explosion in data centers built across the country, as developers try to keep up with demand created by artificial intelligence, cloud storage, and e-commerce. Many of these data centers are being built near residential areas, and the people who live there keep complaining about the noise. Gregory Miller and his colleagues at Trinity Consultants will present their work on noise control strategies for data centers on Monday, May 19, at 8:05 a.m. CT as part of the joint 188th Meeting of the ...

Laying the groundwork to diagnose speech impairments in children with clinical AI #ASA188

2025-05-19
NEW ORLEANS, May 19, 2025 – Speech and language impairments affect over a million children every year, and identifying and treating these conditions early is key to helping these children overcome them. Clinicians struggling with time, resources, and access are in desperate need of tools to make diagnosing speech impairments faster and more accurate. Marisha Speights, assistant professor at Northwestern University, built a data pipeline to train clinical artificial intelligence tools for childhood speech screening. She will present her work Monday, May 19, at 8:20 a.m. CT as part of the joint 188th Meeting of the Acoustical Society of America and 25th International ...

Efficient hybrid environment expression for look-and-step behavior of bipedal walking

2025-05-19
A research paper by scientists at Beijing Institute of Technology proposed an efficient and safe perception method tailored for the look-and-step behavior of bipedal robots. The new research paper, published on Apr. 23 in the journal Cyborg and Bionic Systems, provide an efficient method for representing the surrounding environment as a hybrid of feasible planar regions and a heightmap. The method consists of 2 subsystems: feasible planar region extraction and heightmap construction. The look-and-step behavior of biped robots requires quickly extracting planar regions and obstacles with limited computing resources. “The look-and-step behavior is a strategy ...

Using sound to ‘see’ unexploded munitions on the seafloor #ASA188

2025-05-19
New Orleans, May 19, 2025 – More than 400 underwater sites in the United States are potentially contaminated with unexploded ordnance (UXO) — weapons that did not explode upon deployment, which continue to pose a safety concern. Connor Hodges, a doctoral student at the University of Texas at Austin, studies the changes in the acoustic characteristics of these UXOs after they have been subject to corrosion and biofouling to help detect them underwater. “Many of these sites are in shallow water, potentially posing a threat to human safety, ...

Changes in the aging heart may lessen the risk of irregular heartbeats

2025-05-19
Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC have discovered that microscopic structural changes in the aging heart may reduce the risk of irregular heartbeats. Medically known as arrhythmias, irregular heartbeats become more common with age and can lead to health problems. But a new study in JACC Clinical Electrophysiology, a journal of the American College of Cardiology, revealed that a tiny gap between heart cells called the perinexus naturally narrows with age — an adaptation that may help stabilize heart rhythm. The discovery challenges the ...

Study links dementia care gaps in Quebec to socio-economic status

2025-05-19
A new study has found stark differences in the dementia care received by people in richer and poorer neighbourhoods in Quebec, despite the universal health-care system. The research was led by Dr. Claire Godard-Sebillotte, a Professor in McGill University’s Division of Geriatrics and a researcher at the Research Institute of the McGill University Health Centre. It is the first large-scale study in Quebec to track how social conditions relate to dementia care. The study analyzed health records from about 200,000 people newly diagnosed with dementia between 2000 and 2017. Each patient was followed for a year or until ...

Two CWRU engineering researchers receive early career awards from National Science Foundation

2025-05-19
Two Case Western Reserve University engineering faculty have been awarded National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) grants.  Computer scientist An Wang and environmental engineer Bridget Hegarty were each awarded a five-year grant to support their research programs. Hegarty also received a $1 million grant from the Department of Housing and Urban Development. “These two faculty members pursue two very different lines of research, one around democratizing ...

Exploring the link between overlapping chronic conditions and heart failure in seniors

2025-05-19
Heart failure represents one of the most significant global health challenges, affecting millions worldwide and requiring subsequent hospitalization for many patients due to complications. For older adults in particular, heart failure rarely exists in isolation, often appearing alongside other chronic conditions that may compound its effects.   Because of this, the relationship between cardiovascular disease, kidney dysfunction, and metabolic disorders (such as diabetes) has gained increased attention in recent years. However, most clinical research on this topic has focused primarily on younger populations and excluded adults over 75—despite ...

Metallic glass catalyst paves the way for efficient water splitting

2025-05-19
Hydrogen is a promising clean energy carrier, but its adoption depends on cost-efficient production. Electrochemical water splitting is a key method, yet it relies on scarce and expensive noble metal catalyst. High-entropy metallic glasses (HEMGs) offer a promising alternative due to their amorphous structure and multi-element synergy. However, they often recrystallize during the formation of nanoporous structures via dealloying. The amorphous phase in HEMGs is vital for water splitting due to its disordered ...

After cardiac event, people who regularly sit for too long had higher risk of another event

2025-05-19
Research Highlights: People who were less active, with a daily average of more than 14 hours of sedentary behavior, were more than twice as likely to have another cardiac event, including heart attack, surgery to treat heart issues (coronary revascularization), or to be hospitalized again within a year after the first cardiac event. In the study of approximately 600 people, ages 21 to 96, replacing 30 minutes of sedentary behavior with light-intensity physical activity reduced the risk of another cardiovascular event or death by 50%, and replacing 30 minutes of sedentary time with 30 minutes ...

Streaked slopes on Mars probably not signs of water flow, study finds

2025-05-19
PROVIDENCE, R.I. [Brown University] — A new study by planetary scientists at Brown University and the University of Bern in Switzerland casts doubt on one of the most tantalizing clues that water might be flowing on present-day Mars. For years, scientists have spied strange streaks running down Martian cliffsides and crater walls. Some have interpreted those streaks as liquid flows, suggesting the possibility of currently habitable environments on the Red Planet. But this new study, which used machine ...

Cover crops may not be solution for both crop yield, carbon sequestration

2025-05-19
ITHACA, N.Y. - People have assumed climate change solutions that sequester carbon from the air into soils will also benefit crop yields. But a new study from Cornell University finds that most regenerative farming practices to build soil organic carbon – such as planting cover crops, leaving stems and leaves on the ground and not tilling – actually reduce yields in many situations. The computer model analysis showed that global adoption of such practices to improve soil health can benefit either ...

Researchers take AI to “kindergarten” in order to learn more complex tasks

2025-05-19
We need to learn our letters before we can learn to read and our numbers before we can learn how to add and subtract. The same principles are true with AI, a team of New York University scientists has shown through laboratory experiments and computational modeling. In their work, published in the journal Nature Machine Intelligence, researchers found that when recurrent neural networks (RNNs) are first trained on simple cognitive tasks, they are better equipped to handle more difficult and complex ones later on.  The paper’s authors labeled this form of training kindergarten curriculum learning as it centers on first instilling an ...
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