A new study from Emory University addresses the growing global crisis of antibiotic-resistant infections. Many of these drug-resistant bacteria are spread through hospitals, and there are few antibiotics available for treatment. The study, published in PNAS, looks at a particular bacterium called Acinetobacter baumannii, which is highly infectious, spread mostly in hospitals and typically infects immunocompromised patients. The researchers employed an entirely new strategy to identify weaknesses specific to resistant bacteria and then target these weaknesses with an alternate drug. They found that fendiline, a drug that acts as a calcium channel blocker and ...

UNIVERSITY PARK, Pa. — How educators acquire and implement learnings from their students can play a critical role in environmental education, according to a new study from researchers in the Penn State Department of Recreation, Park, and Tourism Management. The researchers found a role reversal between teachers and students, as environmental educators reported improvement in teaching and leadership skills after learning from the existing knowledge and experiences of students in an environmental education program, demonstrating ...

Among the billions of neurons in the brain, fewer than 500 are responsible for suppressing binge drinking, according to new research by Gilles E. Martin, PhD, associate professor of neurobiology. Published in Nature Neuroscience, these findings provide insights into binge drinking behavior and alcohol dependency that may lead to new therapeutic targets. “It’s really hard to comprehend how only a few neurons can have such a profound effect on behavior,” said Dr Martin, a member of the Brudnick Neuropsychiatric Research Institute at UMass Chan. “This is exciting because we are starting to understand how only a handful of cells are involved in very specific behaviors. ...

Pigs have long been known, sometimes celebrated, as among the most intelligent of farm animals. Now, a new Dartmouth-led study provides evidence that pigs were first domesticated from wild boars in South China approximately 8,000 years ago. China has long been considered one of the locations for original pig domestication but tracking the initial process has always been challenging. The study is the first to find that pigs were eating humans' cooked foods and waste. The results are reported in the Proceedings of the National Academy ...

About The Study: Findings from this cohort study suggest that severe neonatal morbidity may be a significant risk factor for childhood mortality. Efforts to prevent severe neonatal morbidity, as well as early identification and long-term follow-up care, may help further reduce mortality.  Corresponding Author: To contact the corresponding author, Hillary Graham, MS, email hillary.graham@ki.se. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2025.1873) Editor’s Note: Please ...

Infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence compared to children who were healthy as newborns. This is according to a new study from Karolinska Institutet published in the journal JAMA Pediatrics. The study covers over two million babies born in Sweden between 2002 and 2021, about 49,000 (2.4 per cent) of whom had serious health problems in the neonatal period, such as respiratory problems, neurological disorders or severe infections, but survived the first four weeks ...

The three recipients were recognized for their instrumental roles in developing the perovskite solar cell and for taking key steps toward its practical application. This year’s selection focused on the field of environmental and energy materials, with the aim of honoring exceptional achievements pertaining to “energy-related materials and technologies that pave the way toward a sustainable society”. In addition to pioneering the research field of perovskite solar cells, the awardees were responsible for incorporating a critical element, the solid-state hole transport layer, which led to a dramatic improvement of the cell’s stability and ...

Methane emissions from Canada’s non-producing oil and gas wells appear to be seven times higher than government estimates, according to a new study led by researchers at McGill University. The findings spotlight a major gap in the country’s official greenhouse gas inventory and raise urgent questions about how methane leaks are monitored, reported and managed. “Non-producing wells are one of the most uncertain sources of methane emissions in Canada,” said Mary Kang, Associate Professor of Civil Engineering at McGill ...

Traditional Amazonian communities will be using artificial intelligence to help scientists monitor biodiversity in the world’s largest tropical rainforest. The scientists are developing an AI-driven digital toolkit to enable traditional Amazonian communities to monitor and maintain socio-biodiversity in the Amazon region, as well as facilitate their engagement with the bioeconomy. The University of Leicester’s School of Geography, Geology and the Environment and Institute of Environmental Futures have launched a major new research initiative aimed at tackling the growing social-biodiversity and climate challenges facing the Amazon rainforest. Social ...

DARIEN, IL – A new study to be presented at the SLEEP 2025 annual meeting found that teens who get moderate — but not excessive — catch-up sleep on weekends have fewer symptoms of anxiety. Results show that teens who got up to two more hours of sleep on weekends than on weekdays exhibited fewer anxiety symptoms compared with those who did not sleep longer on weekends. However, longer durations of catch-up sleep on weekends were associated with slightly more internalizing symptoms. “The results show that both sleeping less on weekends than weekdays and sleeping substantially more on weekends were associated with ...

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop. Known as circular RNAs (circRNAs), these molecules are crucial for development, thought, and synaptic function, yet their high prevalence in neurons has long been a scientific mystery. How does the brain produce so many of them? Now, Max Planck researchers from Freiburg have discovered a crucial mechanism that explains the remarkable abundance of circRNAs in the nervous system. The study reveals that the protein ELAV ...

1. Research Background Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic disorder worldwide. Beyond glucose dysregulation, it exerts significant effects on the central nervous system. Epidemiological and neuroimaging evidence indicates that individuals with T2DM are at substantially increased risk of cognitive decline and dementia, which is closely linked to degenerative changes in brain structure—particularly within subcortical regions such as the hippocampus, amygdala, caudate, and thalamus. These regions play ...

(Toronto, June 10, 2025) JMIR Publications celebrates its remarkable success in the latest Scopus CiteScore rankings. Providing a current view of journal impact, CiteScore uses Scopus data spanning 2021 to 2024. A total of 26 JMIR Publications’ journals have been awarded a CiteScore this year, demonstrating the exceptional research quality across its portfolio. This accomplishment reinforces the organization’s dedication to progressing the digital health domain. A Closer Look at the CiteScore Results:  First quartile performance: 12 journals ranked within the first quartile (Q1) in their fields, of which 6 journals ranked ...

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors. While similar treatments have worked well for blood cancers, treating solid tumors is more difficult. Their method, published in the Journal for ImmunoTherapy of Cancer, targeted a protein found in high amounts on many types of cancer cells (Eva1), and successfully eliminated tumors in lab mice. CAR-T ...

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress. The proposed recommendations are detailed in a new paper published today in Stem Cell Reports. SCBEMs are three dimensional structures that replicate key aspects of early embryonic development, offering unprecedented potential ...

WASHINGTON, June 10, 2025 – Human development is a beautiful, complex process. Beginning from just two germ cells, the cells divide and double until an entire organism is developed in just under a year. While studying embryos in vitro can have many ethical and technical complications, there is a model that serves as an excellent substitute. Named after the early-development stage of gastrulation, two-dimensional “gastruloids” are made from colonies of human pluripotent stem cells that can replicate the third week of gestation in which the three germ layers of the body are established. In APL Bioengineering, by AIP Publishing, ...

WASHINGTON, June 10, 2025 – Chemistry often conjures images of mixing fluids together in beakers, flasks, or test tubes. But often, chemistry happens on a much smaller scale. In many medical and industrial contexts, mixing fluids involves fractions of a milliliter, and for these applications, sometimes the best tool is a microscopic robot. In Nanotechnology and Precision Engineering, by AIP Publishing, researchers from the Chinese Academy of Sciences and the China Electric Power Research Institute developed a microrobot capable of manipulating small droplets in the presence of magnetic fields. To make their robot, the researchers mixed neodymium magnetic ...

About The Study: This cross-sectional study revealed high attrition rates among lesbian, gay, and bisexual (LGB) medical students, with the highest observed among LGB Hispanic male and female students. Our findings highlight the importance of intersectionality in understanding attrition from medical school. Although future studies need to examine the cause of these disparities in attrition, LGB students experience discrimination within medical training environments, which may lead to risk of attrition. Corresponding Author: To contact the corresponding author, Mytien Nguyen, MS, email mytien.nguyen@yale.edu. To ...

About The Study: This study found that parent-reported firearm storage may be a poor estimator of teen perceived firearm access, regardless of teen gender, parental education, and urbanicity. Strictly focusing safety efforts on locked and unloaded firearm storage may not fully negate teen’s perceptions that they can access and load household firearms. Storing additional firearms securely may not prevent teen access if at least 1 household firearm remains unlocked. Corresponding Author: To contact the corresponding author, Katherine G. Hastings, MPH, email katiegh@student.ubc.ca. To access the embargoed study: Visit our For The Media website at this ...

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us. The more scientists can identify and classify the molecules involved in our metabolism, called metabolites, the more we can learn about human health and disease. Now, researchers at University of California San Diego have made a major advance in our understanding of human metabolism by describing hundreds of new N-acyl lipids, a type of molecule involved in immune and stress responses. The main findings of the study, published in Cell, were: The researchers identified 851 distinct N-acyl lipids across various tissues and biofluids, ...

Astrophysicists have gained precious new insights into how distant “exoplanets” form and what their atmospheres can look like, after using the James Webb Telescope to image two young exoplanets in extraordinary detail. Among the headline findings were the presence of silicate clouds in one of the planet’s atmospheres, and a circumplanetary disk thought to feed material that can form moons around the other.  In broader terms, understanding how the “YSES-1” super-solar system formed offers further insight into the origins of our own solar system, and gives us the ...

As one of the most important industrially viable methods for carbon dioxide (CO2) utilization, methanol synthesis serves as a platform for the production of green fuels and commodity chemicals. For sustainable methanol synthesis, In₂O₃ is an ideal catalyst and has garnered significant attention. Recently, a research team led by Prof. Peng Gao and Prof. Shenggang Li (Shanghai Advanced Research Institute, Chinese Academy of Sciences) conducted an integrated experimental and computational investigation into the structural evolution ...

Tokyo, Japan - There are many factors that contribute to infant language development, not least of which is baby talk—the modified speech mothers and other adults often use when speaking to infants.   Baby talk is more formally referred to as infant-directed speech (IDS) and often differs from adult-directed speech (ADS) in both pitch and vocabulary. One component of IDS that remains controversial, however, is the exaggeration or hyperarticulation of vowel sounds. Some experts contend that vowel exaggeration produces clearer speech sounds ...

The launch of China’s national carbon market has doubled the emissions covered by global carbon pricing mechanisms, making it the world’s largest carbon market. It is expected to be a crucial tool for China in achieving its climate goals of peaking CO2 emissions by 2030 and reaching carbon neutrality by 2060.   A research team composed of members from Tsinghua University and Carnegie Mellon University, recently published a review article in the journal Energy and Climate Management, outlining the development background and process of China’s national ...

“It is not easy to distinguish Type 1 from Type 2, but a clock based on a mixture of Type 1 and Type 2 methylation is likely to produce inconsistent and misleading results, when applied to anti-aging technologies.” BUFFALO, NY — June 10, 2025 — A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled “Methylation clocks for evaluation of anti-aging interventions.” In this perspective article, Dr. Josh Mitteldorf explores how current epigenetic clocks—used ...