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Poorly functioning blood vessels lead to muscle wasting in cancer

2025-05-29
A dysfunction in muscle blood vessels could be to blame for the weak muscles and weight loss that most cancer patients experience, according to a new study from University of Illinois Chicago researchers. The discovery may help cancer survivors regain their muscle strength, which could contribute to better outcomes for these patients, said Dr. Jalees Rehman, senior author of the new paper and the Benjamin J. Goldberg Professor and head of the department of biochemistry and molecular genetics at the College of Medicine. Up to 80% of patients with cancer experience muscle ...

Thousands of sensors reveal 3D structure of earthquake-triggered sound waves

2025-05-29
Earthquakes create ripple effects in Earth's upper atmosphere that can disrupt satellite communications and navigation systems we rely on. Nagoya University scientists and their collaborators have used Japan's extensive network of Global Navigation Satellite System (GNSS) receivers to create the first 3D images of atmospheric disturbances caused by the 2024 Noto Peninsula Earthquake. Their results show sound wave disturbance patterns in unique 3D detail and provide new insights into how earthquakes generate these waves. The results were published in the journal Earth, Planets and Space. Mapping electron density ...

Deep learning-powered denoising technique for high-speed dynamic fluorescence imaging

2025-05-29
A new deep learning-based approach has been developed to overcome one of the critical limitations in fluorescence microscopy: severe image degradation caused by noise in dynamic in vivo imaging environments. The technique, recently published in PhotoniX (May 23, 2025), introduces a self-supervised denoising network—TeD (Temporal-gradient empowered Denoising)—that improves image quality without requiring clean reference images, representing a breakthrough for applications involving rapid biological ...

New understanding of a decades-old bladder cancer treatment could help improve immunotherapies more broadly

2025-05-29
More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer. Now, a team of researchers from Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine is expanding the understanding of how the treatment works — an understanding that could help improve the effectiveness of immunotherapies more broadly. BCG is a weakened strain of the bacterium Mycobacterium bovis, which is used worldwide as a vaccine against childhood tuberculosis. ...

When climate disasters hit, they often leave long-term health care access shortages, Drexel study finds

2025-05-29
Immediate recovery efforts receive the most attention after severe natural disasters, yet new data from researchers at Drexel University and the University of Maryland suggests these climate events often also leave a critical long-term — and often unaddressed — problem in declines in access to health care. The team found a statistically significant link between severe natural disasters, such as heatwaves, droughts, floods and wildfires, and loss of health care infrastructure — including hospitals and outpatient ...

New clues in aortic dissection: Endothelial dysfunction meets immune infiltration

2025-05-29
Tsukuba, Japan—Due to the sudden rupture of the aortic wall, aortic dissection is a life-threatening condition that requires immediate medical attention, as it can lead to vascular collapse. Individuals with inherited connective tissue disorders, such as Marfan syndrome, are particularly at risk, often developing the condition at a young age. This highlights the urgent need for effective preventive and therapeutic strategies. However, the molecular mechanisms that drive the onset and progression of aortic dissection remain poorly understood. In a recent study, an international research team led by the University of Tsukuba created a mouse ...

Polycystic Ovary Syndrome: Raising awareness and changing the name led by experts, health professionals and those with lived experience

2025-05-29
Most experts and those experiencing the potentially debilitating features of Polycystic Ovary Syndrome (PCOS), which affects one in eight women, want greater awareness and a name change to improve care and outcomes. A new Monash University-led research paper reveals those involved are keen to overcome the misleading implication that it is only an ovarian or gynaecological condition. PCOS carries risks of higher body weight, diabetes, heart disease, fertility issues and pregnancy complications, endometrial cancer, ...

City-dwelling monarch butterflies stay put

2025-05-29
Monarch butterflies are famous for their annual migrations, but not all migrate. In recent years, more and more monarchs have been living and breeding year-round in California’s Bay Area, thanks in part to the growing presence of non-native milkweeds in urban gardens. In a new study published in Ecosphere, University of California, Davis, researchers show that these resident butterflies are not connected to the larger population of monarchs known for their late-autumn coastal migrations. Their work suggests that resident monarchs and the non-native milkweeds that sustain them are ...

Electronic tattoo gauges mental strain

2025-05-29
Researchers gave participants face tattoos that can track when their brain is working too hard. Published May 29 in the Cell Press journal Device, the study introduces a non-permanent wireless forehead e-tattoo that decodes brainwaves to measure mental strain without bulky headgear. This technology may help track the mental workload of workers like air traffic controllers and truck drivers, whose lapses in focus can have serious consequences. "Technology is developing faster than human evolution. Our brain capacity cannot keep up and can easily get ...

Public awareness of the association between alcohol and cancer in the U.S.

2025-05-29
About The Study: The findings of this study that fewer than half of U.S. adults are aware and about one-fifth are unsure of their awareness of the association between alcohol and cancer emphasize the need to implement the recently updated Surgeon General’s recommendation to reduce the alcohol-related cancer burden in the U.S. Corresponding Author: To contact the corresponding author, Sanjay Shete, PhD, email sshete@mdanderson.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoncol.2025.1146) Editor’s Note: Please ...

Acupuncture for nocturia in survivors of prostate cancer

2025-05-29
About The Study: In this pilot trial, acupuncture produced greater reductions in nocturia (waking up 1 or more times to urinate) relative to usual care in survivors of prostate cancer. The nocturia reduction was comparable to other treatments, such as desmopressin, α-blockers, and antimuscarinic medications; however, acupuncture was associated with fewer adverse events. Nocturia affects more than half of survivors of prostate cancer. Corresponding Author: To contact the corresponding author, Kevin T. Liou, MD, email liouk@mskcc.org. To access the embargoed ...

New study finds recovery is still possible for critically endangered Hawaiian honeycreeper with urgent intervention

2025-05-29
CONTACT:           San Diego Zoo Wildlife Alliance Public Relations 619-685-3291  publicrelations@sdzwa.org sdzwa.org PHOTOS AND VIDEO: https://sandiegozoo.box.com/s/uzfr25f5xzcgxyj0tgww5ob6nvafuyng NEWS RELEASE New Study Finds Recovery Is Still Possible for Critically Endangered Hawaiian Honeycreeper With Urgent Intervention Latest Genomic Research Offers a Unique Lens for Understanding the Extinction Crisis in Hawai‘i SAN DIEGO (May 29, 2025) – A new scientific study, led by San Diego Zoo ...

All-in-one model reconstructs complex liver architecture

2025-05-29
To the point: New tissue-derived organoid model: A next-generation organoid model, composed of three liver cell types – adult hepatocytes, cholangiocytes, and liver mesenchymal cells – reconstructs the liver periportal region. Organoid functionality: The complex organoids, or assembloids, are functional, consistently draining bile from the bile canaliculi into the bile duct as in the real liver due to their accurate tissue architecture recapitulation. Liver disease modelling: This liver model reconstructs the liver periportal region architecture, is able to model aspects of cholestatic liver injury and biliary ...

Most Americans unaware of cancer risks associated with drinking alcohol

2025-05-29
Despite established connections, study finds almost 60% of U.S. adults are unaware or uncertain of the link between alcohol and cancer  An estimated 75,000 cancer cases are associated with alcohol annually in the U.S.  Researchers suggest implementing new Surgeon General recommendations could be an effective approach to reducing future cancer rates  HOUSTON, MAY 29, 2025 ― Alcohol is a leading preventable cause of cancer, but public awareness of the connection remains strikingly low in the U.S., with ...

New insights into bladder cancer treatment could help improve immunotherapies

2025-05-29
More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer. Now, a team of researchers from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK) and is expanding the understanding of how the treatment works — an understanding that could help improve the effectiveness of immunotherapies more broadly. BCG is a weakened strain of the bacterium Mycobacterium bovis, which is ...

HIV discovery could open door to long-sought cure

2025-05-29
University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding. These insights bring researchers closer to finding ways to flush out the dormant virus and eliminate it for good. Thanks to remarkable progress in HIV treatment, the virus can often be suppressed to undetectable levels in the blood, eliminating most disease symptoms, and preventing transmission to others. But HIV never truly ...

The purrfect gene

2025-05-29
Kyoto, Japan -- Whether you are lucky enough to have a cat companion or must merely live this experience vicariously through cat videos, Felis catus is a familiar and comforting presence in our daily lives. Unlike most other feline species, cats exhibit sociality, can live in groups, and communicate both with other cats and humans, which is why they have been humans' trusted accomplices for millennia. Despite this intimacy, there is still much that we don't know about our feline friends. Numerous behavioral studies have been conducted on other mammal species, but relatively few on cats. In part to fill this gap, a team of researchers at ...

Researchers find promise in a new peptide drug to combat a deadly brain cancer

2025-05-29
A lab-designed molecule developed and extensively studied by scientists with Virginia Tech’s Fralin Biomedical Research Institute at VTC could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive and deadly form of brain cancer. In a study published in May in Cell Death and Disease, researchers identified a previously unknown trait of cancer cells that shows promise for therapeutic intervention. The group outlined the mechanism of action and effectiveness of the experimental drug known as JM2, revealing ...

Two WCM scientists receive inaugural Pershing Square Foundation Ovarian Cancer Challenge Grant

2025-05-29
(New York, May 29, 2025) – Dr. Juan R. Cubillos-Ruiz, the William J. Ledger, M.D. Distinguished Associate Professor of Infection and Immunology in Obstetrics and Gynecology, and Dr. David Lyden, the Stavros S. Niarchos Professor in Pediatric Cardiology, both from Weill Cornell Medicine, have been named inaugural recipients of the Pershing Square Foundation’s 2025 Ovarian Cancer Challenge Grant. The challenge grant provides $750,000 in funding over three years to support innovative research into ovarian cancer ...

Wyss Institute at Harvard University announces appointment of Natalie Artzi, Ph.D., to Associate Institute Director

2025-05-29
Wyss Institute at Harvard University Announces Appointment of Natalie Artzi, Ph.D.,  to Associate Institute Director Dr. Artzi will work closely with the Wyss Founding Director Don Ingber and the Wyss executive and senior leadership teams in shaping the strategic direction of the Institute  MAY 29,2025  – (Boston, MA) – The Wyss Institute at Harvard University, its Board of Directors, and Executive Leadership are pleased to announce that Natalie Artzi, Ph.D. has been appointed to a newly created position as Associate Institute Director ...

Earlier measles vaccine could help curb global outbreak

2025-05-29
The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review states. The systematic review, led by Murdoch Children’s Research Institute (MCRI), found vaccinating children from as early as four months of age for measles warranted serious discussion given that only 30 per cent of babies in low- and middle-income countries were protected by maternal antibodies by four months of age. Concerningly, this is well below the World Health Organization’s (WHO) recommendation of a first measles dose between 9-12 months old. The ...

Mixed-valence Cu-based metal-organic framework enables highly efficient CO2 electroreduction to C1 liquid fuels

2025-05-29
Rising atmospheric CO2 levels from fossil fuel dependence have intensified climate threats, driving demand for technologies that convert CO2 into value-added chemicals. Electrocatalytic CO2 reduction (CO2RR) holds promise but faces challenges such as high energy costs, low product selectivity, and competition from hydrogen evolution reactions (HER). A breakthrough by researchers at Tongji University, China, introduces a new catalyst design that overcomes these limitations, paving the way for green chemistry solutions.   The ...

The future of AI regulation: why leashes are better than guardrails

2025-05-29
Herndon, VA, May 29, 2025 – Many policy discussions on AI safety regulation have focused on the need to establish regulatory “guardrails” to protect the public from the risks of AI technology. In a new paper published in the journal Risk Analysis, two experts argue that, instead of imposing guardrails, policymakers should demand “leashes.”   Director of the Penn Program on Regulation and professor at University of Pennsylvania Carey Law School, Cary Coglianese and University of ...

Income inequality undermines support for higher minimum wages

2025-05-29
High levels of income inequality weaken support for raising the minimum wage, which in turn could further worsen income inequality as people believe this is the way things should be, according to research published by the American Psychological Association.  The researchers analyzed data from more than 130,000 protests across the country and conducted eight other experiments that found that an “is-to-ought” reasoning error may be to blame where people view situations as they are and then infer that is the way they should be. That can have ...

Lateral walking gait recognition and hip angle prediction using a dual-task learning framework

2025-05-29
Lateral walking exercise is beneficial for the hip abductor enhancement. Accurate gait recognition and continuous hip joint angle prediction are essential for the control of exoskeletons. “The hip exoskeleton is a promising tool for enhancing muscle activation during lateral walking exercises by providing controlled resistance a support. This ensures adequate muscle exercise for effective rehabilitation. Our team has previously designed a resistance lateral walking exercise exoskeleton. Accurate gait recognition and continuous joint angle prediction are the precondition of the good control performance of the exoskeleton.” Explained study author Wujing Cao, a professor at Chinese ...
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