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Breaking carbon–hydrogen bonds to make complex molecules

Breaking carbon–hydrogen bonds to make complex molecules
2024-11-08
A team of scientists led by Caltech and Emory University has synthesized a highly complex natural molecule using a novel strategy that functionalizes normally nonreactive bonds, called carbon–hydrogen (C–H) bonds. The work demonstrates a new category of reactions that organic chemists can consider as they work to create natural products that could be used in pharmaceuticals or new materials, or to produce organic chemicals in more sustainable ways.   "This work moves the field forward by showing the power of C–H functionalization," says ...

Sometimes you're the windshield: Utah State University researcher says vehicles cause significant bee deaths

Sometimes youre the windshield: Utah State University researcher says vehicles cause significant bee deaths
2024-11-08
LOGAN, UTAH, USA -- When a large mammal such as a deer or a moose is struck by a motor vehicle, the damage is usually dramatic. To reduce these unfortunate events, transportation officials have teamed with wildlife researchers to place warning signs, and to construct wildlife underpasses and overpasses, to mitigate mishaps along animal migration paths. In contrast, collisions with much smaller bees often go unnoticed or are perceived by motorists as simply an annoying splat on a windshield. The significance, Utah State University ...

AMS Science Preview: Turbulence & thunderstorms, heat stress, future derechos

2024-11-08
The American Meteorological Society continuously publishes research on climate, weather, and water in its 12 journals. Many of these articles are available for early online access–they are peer-reviewed, but not yet in their final published form. Below is a selection of articles published early online recently. Some articles are open-access; to view others, members of the media can contact kpflaumer@ametsoc.org for press login credentials. JOURNAL ARTICLES A New Heat Stress Index For Climate Change Assessment Bulletin of the American Meteorological Society Heat Index may dramatically underestimate heat stress in extreme temperatures. This work compares the ...

Study of mountaineering mice sheds light on evolutionary adaptation

Study of mountaineering mice sheds light on evolutionary adaptation
2024-11-08
Teams of mountaineering mice are helping advance understanding into how evolutionary adaptation to localized conditions can enable a single species to thrive across diverse environments. In a study led by Naim Bautista, a postdoctoral researcher in Jay Storz’s lab at the University of Nebraska–Lincoln, the team took highland deer mice and their lowland cousins on a simulated ascent to 6,000 meters. The “climb” ventured from sea level and the mice reached the simulated summit seven weeks later. Along the way, Bautista tracked how the mice responded to cold stress at progressively lower oxygen levels. “Deer ...

Geologists rewrite textbooks with new insights from the bottom of the Grand Canyon

Geologists rewrite textbooks with new insights from the bottom of the Grand Canyon
2024-11-08
LOGAN, UTAH, USA – Any boomer, gen xer, millennial, gen zer or alpha who’s studied geology has likely gained foundational knowledge from Edwin Dinwiddie McKee’s landmark studies of the Grand Canyon’s sedimentary record – even if they don’t readily recognize McKee’s name. The legendary scientist, who lived from 1906-1984, studied and documented the stratigraphy and sedimentation of Colorado Plateau geology, especially the Grand Canyon’s Cambrian Tonto Group, for more than 50 years. His time-tested ...

MSU researcher develops promising new genetic breast cancer model

2024-11-08
A Michigan State University researcher’s new model for studying breast cancer could help scientists better understand why and where cancer metastasizes. Professor https://directory.natsci.msu.edu/Directory/Profiles/Person/103559 who teaches in the MSU Department of Physiology, has been researching the E2F5 gene, of which little is known, and its role in the development of breast cancer. Based on findings from Andrechek’s lab, the loss of E2F5 results in altered regulation of Cyclin D1, a protein linked to metastatic breast tumors after long ...

McCombs announces 2024 Hall of Fame inductees and rising stars

2024-11-08
AUSTIN, Texas — Friends and distinguished alumni of the McCombs School of Business at The University of Texas at Austin inducted four alumni into the school’s Hall of Fame on Nov. 7 at the AT&T Hotel and Conference Center. This year’s honorees are Christopher Bake, BBA ’88; Ray Brimble, B.A. ’74; Bennett Glazer, BBA ’68; and Brien Smith, BBA ’79, MPA '81. McCombs Dean Lillian Mills also recognized 2024 Rising Stars Simeon Bochev, MSF ’13; Michael Ginnings, BBA ’09; and Gerardo Guardado, MBA ’10. The ...

Stalling a disease that could annihilate banana production is a high-return investment in Colombia

Stalling a disease that could annihilate banana production is a high-return investment in Colombia
2024-11-08
There’s no cure for a fungal disease that could potentially wipe out much of global banana production. Widespread adoption of cement paths, disinfection stations, and production strategies could net 3-4 USD of benefits for each dollar invested in Colombia.  Hundreds of millions of dollars in banana exports from Colombia are at risk due to a fungal disease best known as Tropical Race 4 (TR4). First detected in Asia in the 1990s, the Fusarium fungus that causes the disease arrived in Colombia in 2019, completing its inevitable global spread to South America, the last major banana production continent that remained TR4-free. Researchers are confident ...

Measurements from ‘lost’ Seaglider offer new insights into Antarctic ice melting

Measurements from ‘lost’ Seaglider offer new insights into Antarctic ice melting
2024-11-08
New research reveals for the first time how a major Antarctic ice shelf has been subjected to increased melting by warming ocean waters over the last four decades. Scientists from the University of East Anglia (UEA) say the study - the result of their autonomous Seaglider getting accidentally stuck underneath the Ross Ice Shelf - suggests this will likely only increase further as climate change drives continued ocean warming. The glider, named Marlin, was deployed in December 2022 into the Ross Sea from the edge of the sea ice. Carrying a range of sensors to collect data on ocean processes that are important for climate, it was programmed to travel northward into ...

Grant to support new research to address alcohol-related partner violence among sexual minorities

Grant to support new research to address alcohol-related partner violence among sexual minorities
2024-11-08
Navigating the intersection of alcohol use and intimate partner violence amongst young couples is not an easy journey, and for bisexual+ couples, the road may be even more winding.   “No study has examined the extent to which alcohol use increases intimate personal violence among bisexual+ young adults or daily experiences unique to them. Our study will look at factors such as minority stressors that may lead to alcohol-related partner violence,” said Meagan Brem, director of the Research for Alcohol and Couple’s Health Lab at Virginia Tech. Alcohol use and intimate partner violence - defined as any action in a ...

Biodiversity change amidst disappearing human traditions

Biodiversity change amidst disappearing human traditions
2024-11-08
A Branco Weiss Fellowship – Society in Science has been awarded to Dr Gergana Daskalova. The fellowship funds Daskalova’s research project “Biodiversity change amidst disappearing human traditions and changing socio-economics”. She joins the Department of Conservation Biology at the University of Göttingen to work together with Professor Johannes Kamp. The five-year fellowship, which is worth over €530,000, will enable Daskalova to investigate the ecological and human fingerprints of land abandonment. Considering the question from both a local and a global perspective, Daskalova’s research will reveal what happens to nature when people leave, ...

New approaches to synthesize compounds for pharmaceutical research

2024-11-08
Junior Professor Johannes Walker, University of Göttingen, has been awarded an Exploration Grant from the Boehringer Ingelheim Foundation. Walker teaches and carries out research at the Institute for Organic and Biomolecular Chemistry. The award of 180,000 euros will enable Walker and his team to develop new approaches to synthesizing new compounds.   “The aim of our project is to develop new strategies for the synthesis of a particular group of new chemical compounds,’ Walker explains. These compounds are called saturated polycyclic molecules. They are structurally complex ...

Cohesion through resilient democratic communities

2024-11-08
A new EU joint research project led by the University of Göttingen will explore how migration, demographic change and current crises are affecting social cohesion and democratic structures in Europe. A key objective is to find out how resilient democratic structures can strengthen local communities in times of profound demographic change. The project “Identities - Migration - Democracy (We-ID)” has been awarded funding of around three million euros over three years by the European Union.   European societies are undergoing a profound demographic transformation: falling birth rates, rising life expectancy and migration are increasingly ...

UC Santa Cruz chemists discover new process to make biodiesel production easier, less energy intensive

UC Santa Cruz chemists discover new process to make biodiesel production easier, less energy intensive
2024-11-08
UC Santa Cruz chemists have discovered a new way to produce biodiesel from waste oil that both simplifies the process and requires relatively mild heat. This discovery has the potential to make the alternative fuel source much more appealing to the massive industrial sectors that are the backbone of the nation’s economy. In 2022, the U.S. transportation sector alone used about 3 million barrels of diesel per day, accounting for about 75% of total consumption of the fuel in this country. That same year, ...

MD Anderson launches Institute for Cell Therapy Discovery & Innovation to deliver transformational new therapies

MD Anderson launches Institute for Cell Therapy Discovery & Innovation to deliver transformational new therapies
2024-11-08
HOUSTON ― The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need. The institute will bring together top scientists and clinicians to lead exceptional discovery, translational and clinical research that will deliver new insights in immunology and cell engineering, fueling the creation of transformational new treatments that can be rapidly adapted to address emerging needs in cancer, autoimmune diseases, infections ...

New quantum encoding methods slash circuit complexity in machine learning

New quantum encoding methods slash circuit complexity in machine learning
2024-11-08
A recent study by researchers from CSIRO and the University of Melbourne has made progress in quantum machine learning, a field aimed at achieving quantum advantage to outperform classical machine learning. Their work demonstrates that quantum circuits for data encoding in quantum machine learning can be greatly simplified without compromising accuracy or robustness. This research was published Sept.12 in Intelligent Computing, a Science Partner Journal. The team’s results, validated through both simulations and experiments on IBM quantum devices, show that their innovative encoding methods reduced circuit ...

New research promises an unprecedented look at how psychosocial stress affects military service members’ heart health

2024-11-08
A University of Massachusetts Amherst researcher will examine the role of cumulative psychosocial stress – as well as race, ethnicity and gender – among U.S. military personnel to gauge their impact on cardiovascular health and healthcare utilization. The study is funded with a $1 million grant from the Defense Health Agency, part of the Department of Defense (DoD). The findings will help the military develop programs for health promotion and health readiness for active duty and Reserve/National ...

Faster measurement of response to antibiotic treatment in sepsis patients using Dimeric HNL

2024-11-08
The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis. The first promising results in this regard were published in 2019 and now the research group has confirmed these results in a larger study. The study is published in the journal PLOS ONE. Sepsis, the costliest disease to health care, is a life-threatening condition with high mortality if not diagnosed and ...

Cleveland Clinic announces updated findings in preventive breast cancer vaccine study

Cleveland Clinic announces updated findings in preventive breast cancer vaccine study
2024-11-08
November 8, 2024, CLEVELAND: Cleveland Clinic researchers are presenting updated findings from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.   The study team found that the investigational vaccine was generally well tolerated and produced an immune response in most patients. The team described the side effects of the vaccine, showed the highest tolerated dose to date, and presented the immunologic effects of the vaccine. Findings are being presented at the Society for Immunotherapy of Cancer Annual Meeting.   Launched in 2021 and funded by the U.S. Department of Defense, the ongoing ...

Intergenerational effects of adversity on mind-body health: Pathways through the gut-brain axis

2024-11-08
The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, “Intergenerational Effects of Adversity on Mind-Body Health: Pathways Through the Gut-Brain Axis” on Tuesday, November 12, 2024, at 2:00 pm ET. The presenter, Bridget Laura Callaghan, Ph.D., is an Assistant Professor in the Department of Psychology at the University of California, Los Angeles (UCLA). At UCLA, Dr. Callaghan directs the Brain & Body Lab in the Department of Psychology and also heads the Mental Disorders and Pain research theme at the Goodman Luskin Microbiome Center. The webinar host, Jeffrey Borenstein, M.D., is the President ...

Watch this elephant turn a hose into a sophisticated showering tool

Watch this elephant turn a hose into a sophisticated showering tool
2024-11-08
Tool use isn’t unique to humans. Chimpanzees use sticks as tools. Dolphins, crows, and elephants are known for their tool-use abilities, too. Now a report in the Cell Press journal Current Biology on November 8, 2024, highlights elephants’ remarkable skill in using a hose as a flexible shower head. As an unexpected bonus, researchers say they also have evidence that a fellow elephant knows how to turn the water off, perhaps as a kind of “prank.” “Elephants are amazing with hoses,” says Michael Brecht ...

Chimpanzees perform better on challenging computer tasks when they have an audience

Chimpanzees perform better on challenging computer tasks when they have an audience
2024-11-08
When people have an audience watching them, it can change their performance for better or worse. Now, researchers reporting in the Cell Press journal iScience on November 8 have found that chimpanzees’ performance on computer tasks is influenced by the number of people watching them. The findings suggest that this “audience effect” predates the development of reputation-based human societies, the researchers say. “It was very surprising to find that chimpanzees are affected in their task performance by ...

New medical AI tool identifies more cases of long COVID from patient health records

2024-11-08
KEY TAKEAWAYS Researchers from Mass General Brigham are leveraging artificial intelligence to help identify the signs of long COVID, track how different symptoms manifest over time, and eliminate alternative explanations for patients’ symptoms. The new approach suggests that 22.8% of the population experience the symptoms of long COVID, a figure that may paint a more realistic picture of the pandemic’s long-term toll. Through analyzing a patient’s history over time, this new AI tool ...

Heat waves and adverse health events among dually eligible individuals 65 years and older

2024-11-08
About The Study: In this time-series study, heat waves were associated with increased adverse health events among dually eligible individuals 65 years and older. Without adaptation strategies to address the health-related impacts of heat, dually eligible individuals are increasingly likely to face adverse outcomes.  Corresponding Author: To contact the corresponding author, Hyunjee Kim, PhD, email kihy@ohsu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2024.3884) Editor’s Note: Please ...

Catastrophic health expenditures for in-state and out-of-state abortion care

2024-11-08
About The Study: In this cross-sectional study of U.S. patients seeking abortion, many individuals and their households were estimated to incur catastrophic health expenditures, particularly those traveling from out of state. The financial and psychological burdens of abortion seeking have likely worsened after the Dobbs decision, as more people need to cross state lines to reach abortion care. The findings suggest expansion of insurance coverage to ensure equitable access to abortion care, irrespective of people’s state of residence, ...
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