How the dirt under our feet could affect human health
2024-12-12
Soil plays a much bigger role in the spread of antibiotic resistance than one might imagine.
Surprisingly, the ground beneath us is packed with antibiotic resistance genes (ARGs) — tiny codes that allow bacteria to resist antibiotics. Human activities, such as pollution and changing land use, can disturb soil ecosystems and make it easier for resistance genes to transfer from soil bacteria and infect humans.
Jingqiu Liao, assistant professor in civil and environmental engineering, is on a mission to understand how soil bacteria contribute to ...
Screen time is a poor predictor of suicide risk, Rutgers researchers find
2024-12-12
For parents trying to shield their children from online threats, limiting screen time is a common tactic. Less time scrolling, the rationale goes, means less exposure to the psychological dangers posed by social media.
But research from Rutgers University-New Brunswick upends this assumption. Writing in The Journal of Child Psychology and Psychiatry, Jessica L. Hamilton, an assistant professor in the Department of Psychology at the School of Arts and Sciences, reports that screen time ...
Dual-unloading mode revolutionizes rice harvesting and transportation
2024-12-12
In a recent study published in Engineering, a team of researchers led by Wenyu Zhang from South China Agricultural University has developed a groundbreaking cotransporter system that combines a tracked rice harvester and transporter for fully autonomous harvesting, unloading, and transportation operations.
The key innovation of this system lies in the proposed dual-unloading mode, which includes two distinct methods: harvester waiting for unloading (HWU) and transporter following for unloading (TFU). In the HWU system, the harvester halts and summons the transporter when its ...
Researchers uncover strong light-matter interactions in quantum spin liquids
2024-12-12
Physicists have long theorized the existence of a unique state of matter known as a quantum spin liquid. In this state, magnetic particles do not settle into an orderly pattern, even at absolute zero temperature. Instead, they remain in a constantly fluctuating, entangled state. This unusual behavior is governed by complex quantum rules, leading to emergent properties that resemble fundamental aspects of our universe such as the interactions of light and matter. Despite its intriguing implications, experimentally proving ...
More dense, populated neighborhoods inspire people to walk more
2024-12-12
SPOKANE, Wash. – Adding strong evidence in support of “walkable” neighborhoods, a large national study found that the built environment can indeed increase how much people walk.
The study, published in the American Journal of Epidemiology, showed a strong connection between place and activity by studying about 11,000 twins, which helps control for family influences and genetic factors. The researchers found that each 1% increase in an area’s “walkability” resulted in 0.42% increase in neighborhood walking. When scaled up, that means a 55% increase in the walkability of the surrounding neighborhood ...
Innovative biomimetic superhydrophobic coating combines repair and buffering properties for superior anti-erosion
2024-12-12
The long-term erosion and corrosion issues during the development of offshore oil and gas fields pose significant threats to the safe and efficient operation of these facilities. Superhydrophobic coatings, known for their ability to reduce interactions between corrosive substances and substrates, have garnered considerable attention. However, their poor mechanical properties often hinder their long-term application in practical working environments. To address this challenge, a research team led by Prof. Yuekun Lai from Fuzhou University and Prof. Xuewen Cao from China University of Petroleum (East China) has developed a biomimetic dental enamel coating with ...
New analytical approach revolutionizes reliability evaluation of power systems with renewable energy
2024-12-12
In a recent study published in Engineering, a team of researchers led by Bo Hu and Changzheng Shao from Chongqing University in China has introduced a novel method for evaluating the real-time dynamic reliability of composite power systems integrated with renewable energy sources (RES). The research addresses the challenges posed by the uncertainties associated with RES, which have been a significant obstacle in ensuring the stable and reliable operation of power grids.
The increasing integration of RES, such as wind and solar power, into the power grid has brought about concerns regarding power imbalance and load shedding due to their ...
Artificial intelligence improves mammography-based risk prediction
2024-12-12
The future of breast cancer screening and risk-reducing strategies is being shaped by artificial intelligence (AI), according to a review article published by Cell Press on December 12 in the journal Trends in Cancer.
“We discuss recent advances in AI-assisted breast cancer risk prediction, what this means for the future of breast cancer screening and prevention, and the key research needed to progress mammographic features from research into clinical practice,” says senior study author Erik Thompson of the Queensland University of Technology in Brisbane, Australia.
Breast tissue that appears white on ...
Brain tumors hijack circadian clock to grow
2024-12-12
Virtually every cell in the human body has an internal clock. These clocks take their cues from a central clock in the brain. In a normal, biological process called synchrony, the central clock coordinates daily rhythms around the body, so that every cell and tissue recognizes the same external time of day.
Knowing local time helps our bodies to regulate essential processes, including when to sleep and wake, when to eat and what temperature to maintain, among many other important functions.
But a deadly interloper is keeping time the same ...
Pfizer-BioNTech vaccine for COVID-19 among children ages 5-17
2024-12-12
About The Study: The results of this study suggest that the BNT162b2 XBB vaccine (Pfizer-BioNTech) provided protection against COVID-19–associated hospitalization and emergency department or urgent care visits among children 5 to 17 years of age during the 2023-2024 season with estimated vaccine effectiveness point estimates ranging from 63% to 73%.
Corresponding Author: To contact the corresponding author, Sara Y. Tartof, PhD, MPH, email Sara.Y.Tartof@kp.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.49944)
Editor’s ...
Trends in school mental health and substance use education
2024-12-12
About The Study: From 2008-2020, teachers reported an increase in emotional/mental health and suicide prevention in schools, along with related teacher training. However, they reported a decrease in substance use prevention, particularly among middle schools, and no change in teacher training. Substance use during early adolescence is associated with risk for long-term addiction, and middle schools may be underused for prevention.
Corresponding Author: To contact the corresponding author, Chloe Gao, BHSc, email chloe.gao@childrens.harvard.edu.
To ...
Genes that determine tooth shape identified
2024-12-12
Genetic variants that determine the shape of your teeth – including a gene inherited from Neanderthals – have been identified by a team co-led by UCL researchers.
In a new paper published in Current Biology, scientists found substantial tooth differences between ethnicities, potentially due in part to a gene inherited from Neanderthals that was only found in study participants of European origin.
Co-lead author Dr Kaustubh Adhikari (UCL Genetics, Evolution & Environment and The Open University) said: “Teeth ...
With a little help from their friends: Poll shows role of close friendships in older adults’ health
2024-12-12
Whether they’re lifelong buddies or recently connected, close to home or miles away, a new poll shows the key role that friends play in the lives and wellbeing of adults aged 50 and older.
But it also reveals some challenges for those who have physical health or mental health issues – suggesting it may be important for them connect with existing friends or make new friends.
In all, 90% of people aged 50 and older say they have at least one close friend, and 75% say they have enough close friends, ...
Too much screen time can reduce sleep quality in preschool-age children, making behavioral problems worse
2024-12-12
Excessive screen use by preschool-age children can lead to reduced sleep quality, exacerbating problems such as poor attention, hyperactivity and unstable mood, a new study suggests.
Peer-reviewed findings published in Early Child Development and Care show how screen time is “significantly” correlated with increased hyperactive attention problems and emotional symptoms, and with decreased sleep quality.
Additionally, the research – carried out by experts in China and Canada – demonstrates how sleep quality is also extensively correlated with decreased hyperactive attention problems, emotional symptoms and peer problems.
The findings ...
Study reveals role of allele dosage in improving sweetpotato traits
2024-12-12
Sweetpotatoes are an agricultural powerhouse that feeds millions globally. However, their complex genetics make it challenging for breeders to understand and improve traits like yield, disease resistance, and nutritional content. A new study reveals insights into the significance of leveraging “allele dosages” in sweetpotato breeding practices.
“Sweetpotatoes are hexaploid, meaning they have six copies of each chromosome, unlike diploid crops like tomato or rice, which have two," explained Zhangjun Fei, a professor at the Boyce Thompson Institute and one of the study's lead authors. “This genetic ...
Dan M. Frangopol and Sunyong Kim co-author third book on structural performance
2024-12-12
Dan M. Frangopol, the inaugural Fazlur R. Khan Endowed Chair of Structural Engineering and Architecture at Lehigh University, has co-authored a new book on probabilistic structural performance assessments.
System Reliability, Risk, Longevity, Sustainability and Optimal Decision-Making: Emphasis on Marine Structures (available April 11, 2025) offers a comprehensive framework for analyzing and predicting the time-dependent performance of deteriorating structures. The book emphasizes marine infrastructure, addressing system reliability, risk, longevity, sustainability, and optimal decision-making processes. It is a valuable resource for students, engineers, researchers, decision-makers, ...
Ferroptosis and intrinsic drug-induced liver injury by acetaminophen and other drugs: a critical evaluation and historical perspective
2024-12-12
DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause dose-dependent injury, while idiosyncratic DILI involves complex immune and metabolic interactions that remain poorly understood. Mechanistic studies of intrinsic hepatotoxins have revealed oxidative stress and mitochondrial dysfunction as key contributors to injury. Historically, LPO and iron-catalyzed free radical generation were central to understanding DILI, but the focus shifted toward apoptosis in the late 20th century.
The discovery of ferroptosis—a regulated form of cell death characterized ...
Reiki therapy demonstrates significant symptom relief for cancer patients receiving infusion treatments
2024-12-12
CLEVELAND - A recent study conducted at University Hospitals Connor Whole Health has evaluated a Reiki program designed for outpatients with cancer and receiving infusion treatments at two University Hospitals infusion centers.
The study, entitled “Evaluation of a Reiki Volunteer Program within Two Cancer Infusion Centers,” was recently published in the Journal of Pain and Symptom Management, a peer-reviewed journal that serves as an interdisciplinary audience of professionals. This retrospective review, conducted between March 2022 and February 2024, evaluated the effects of Reiki on outpatients receiving infusion treatments such as chemotherapy. During Reiki sessions, a ...
Long-term exposure to air pollution linked to blood clots in veins that bring blood to the heart
2024-12-12
WHAT: A large study found that greater exposure to long-term air pollution was linked with increased risks for blood clots that can occur in deep veins, which, if untreated, can block blood flow and cause serious complications, even death.
These findings came from a longitudinal study funded by the National Institutes of Health (NIH) that included 6,651 U.S. adults who were followed for an average of 17 years between 2000 and 2018. Participants lived in or near one of six major metropolitan areas: New York, Baltimore, Chicago, Los Angeles, Minneapolis, and Winston-Salem, North Carolina.
Throughout the study, 248 adults, 3.7% of the study sample, developed blood clots ...
National Academy of Inventors partners with PMU to recognize three exceptional innovators
2024-12-12
The National Academy of Inventors (NAI) is proud to announce the recipients of the inaugural Prince Mohammad bin Fahd University (PMU)-National Academy of Inventors International Patent Award. This year’s recipients will be honored at a special ceremony on December 12th, 2024 at PMU’s campus in Al-Khobar, Kingdom of Saudi Arabia.
The PMU-NAI International Patent Award was created to recognize and honor distinguished scientists, research institutions, research centers, and universities across the globe for their outstanding patents and inventions that create positive societal ...
Deep learning model accurately diagnoses COPD
2024-12-12
OAK BROOK, Ill. – Using just one inhalation lung CT scan, a deep learning model can accurately diagnose and stage chronic obstructive pulmonary disease (COPD), according to a study published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA).
COPD is a group of progressive lung diseases that impair a person’s ability to breathe. Symptoms typically involve shortness of breath and fatigue. There currently is no cure for COPD, and it is the third leading cause of death worldwide, according to the World Health Organization.
A ...
Alliance Foundation Trials phase III PATINA study shows promise for patients with HR+, HER2+ metastatic breast cancer
2024-12-12
Alliance Foundation Trials, LLC (AFT) and Pfizer Inc. today announced results from the phase III PATINA trial demonstrating that the addition of palbociclib (IBRANCE®) to current standard-of-care first-line maintenance therapy (following induction chemotherapy) resulted in statistically significant and clinically meaningful improvement in progression-free survival (PFS) by investigator assessment in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-positive (HER2+) metastatic ...
COMET trial finds quality of life similar among patients with low- risk DCIS whether they received active monitoring or surgery
2024-12-12
SAN ANTONIO – Patients with low-risk ductal carcinoma in situ (DCIS) who underwent active monitoring reported comparable physical, emotional, and psychological outcomes to patients who received upfront treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.
The results of this study were simultaneously published in JAMA Oncology.
“Active monitoring” is a strategy in which patients are monitored closely, with surgery reserved for those patients who ...
Adjuvant tamoxifen may reduce recurrence risk for patients with ‘good-risk’ DCIS who forgo radiation
2024-12-12
SAN ANTONIO – For patients with “good-risk” ductal carcinoma in situ (DCIS) who underwent breast- conserving surgery and did not receive radiotherapy, tamoxifen significantly decreased the risk of recurrence in the same breast, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.
“Good-risk” DCIS was defined as grade 1 or 2, 2.5 cm or smaller, and having clear surgical margins of 3 mm or greater.
Current guidelines from the National Comprehensive Cancer Network (NCCN) advise that patients who undergo breast-conserving surgery after a diagnosis ...
COMET trial finds active monitoring is a viable option for some patients with low-risk DCIS
2024-12-12
SAN ANTONIO – Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast cancer recurrence rates as those who underwent guideline-concordant treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.
The results of this study were simultaneously published in JAMA.
“Active monitoring” is a strategy in which patients are monitored closely, with surgery reserved for those patients who develop cancer.
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