“GT is a fascinating evolutionary phenomenon observed in lower species and humans, albeit with differing impacts and mechanisms.” BUFFALO, NY- August 9, 2024 – A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, “Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization.” The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant challenge in grasping cancer evolution, tumor genetic heterogeneity, and treatment response. Earlier research has revealed the role of circulating tumor DNA (ctDNA) in mediating the gene expression among ...

ZrC has drawn wide attention as an anti-ablation coating material for lightweight C/C composites but is limited by the produced porous and loose ZrO2 film. To address this issue, the second phase is introduced to improve the densification of the formed Zr-X-O film. Such as ZrC-SiC/TaC coating, the produced low-melting-point oxides, SiO2 (Tm=1650 °C), Ta2O5 (Tm=1800 °C) and Zr6Ta2O17 (Tm=1900 °C), helped to form a dense oxides film. However, the high service temperature causes heat accumulation and a large thermal stress gradient on the surface of the coatings, which will result in large local defects and accelerate the failure of the coating. To decrease the ablation heat ...

Fukuoka, Japan—The SDGs Design International Awards 2024 are calling for students worldwide to submit their original ideas for using design to achieve Sustainable Development Goals.  First organized in 2019 and led by Faculty of Design, Kyushu University, the awards aim to demonstrate the power of design in solving social problems and to elevate society's expectations for design. Now in its sixth year, this year’s theme is “Let’s Create Sustainable Design for FOOD." ...

Along with all the coffee we drink every day, over 6 million tons of spent coffee grounds are produced annually worldwide. Some of these grounds are reused as biofuel but the rest are disposed of in landfills. Over the last decade, research has focused on how to reuse these grounds. The primary focus has been on the polysaccharides from the cellulose and hemicellulose in the ground up coffee bean’s cell walls. Polysaccharides are used in composites, biopolymers, food packaging, construction materials and cellulose nanofibers (CNFs). CNFs specifically, which are cellulose reduced to nanoparticle size, 3 to 5 ...

As the effects of a changing climate and other ecological insults compound, many coral reefs face severe perturbations and a generally poor prognosis for recovery. In an article published in BioScience's new "Perspective and Insight" category, Dr. Peter J. Edmunds of California State University, Northridge, argues for the continued monitoring of coral reefs, even when the seascapes they inhabit are in a significantly degraded state. Drawing from his ongoing 37-year study in the US Virgin Islands, Edmunds argues that "only consistent, rigorous, and detail-oriented ...

Rockville, MD (8/9/2024) – The AIM-HI Accelerator Fund today announces Margaret Foti, PhD, MD (hc), Chief Executive Officer of the American Association for Cancer Research (AACR), is selected unanimously by the 2024 Blue Ribbon Selection Committee as the recipient of the 2024 Beacon Award for Women Leaders in Oncology, from a pool of outstanding global nominees.   The Beacon Award for Women Leaders in Oncology was established in 2022 by the AIM-HI Accelerator Fund and sponsored by the National Foundation for Cancer Research (NFCR). The Beacon Award recognizes outstanding women leaders in health and life sciences who have significantly impacted cancer ...

In a July 9 ceremony, Thomas Abbruscato, Ph.D., and Min Kang, Pharm.D., became the first recipients of the Douglas Stocco Research Chair, an endowment formerly known as the Texas Tech University Health Sciences Center’s (TTUHSC) Research Endowment. The Texas Tech University System Board of Regents officially renamed the endowed chair in late November 2023 and made two appointments available.  Abbruscato, professor and chair in the Department of Pharmaceutical Sciences at the TTUHSC Jerry H. Hodge School of Pharmacy, said it is an honor to receive the endowment. “Personally, I am humbled to have ...

The natural world is rich in chemical compounds with remarkable medicinal properties. A notable example is penicillin, discovered by chance from the Penicillium mold. This discovery revolutionized the treatment of bacterial infections and highlighted the potential of natural compounds in medicine. Since then, the identification, isolation, and synthesis of novel bioactive compounds from plants, fungi, and bacteria have become fundamental to drug development. Recently, two groups of naturally occurring bioactive compounds have garnered significant attention: violaceoids A–F ...

New research from the University of Adelaide has shown that glossy black-cockatoos prefer to feed from trees growing in acidic soils. Glossy black-cockatoos are seed-eating birds that feed almost exclusively on the cones of drooping sheoak trees. However, counterintuitively, they select trees that grow on the poorest soils found on ancient sedimentary rocks. “Sheoak trees are three times more likely to be used as feeding trees if they are growing on non-limestone sedimentary rocks,” says Dr Gay Crowley, from the University of Adelaide’s School of Social Sciences. Dr Crowley compared 6,543 feeding records with 23,484 ...

Autistic youth who were born in underserved neighborhoods are more likely to have greater attention deficit hyperactivity disorder (ADHD) symptoms than those born in communities with more resources. This is one finding of a new study led by researchers at the UC Davis MIND Institute.   This is the first time researchers have investigated how neighborhood factors are associated with ADHD in autistic and non-autistic children. The study provides new insights into mental health conditions and has the potential to inform public policy changes to improve health equity. It was published in the journal JCPP Advances. “We found that some neighborhood ...

Content warning: This post contains details of sharing intimate imagery without consent that may be disturbing to some readers. While much attention on sexually explicit “deepfakes” has focused on celebrities, these non-consensual sexual images and videos generated with artificial intelligence harm people both in and out of the limelight. As text-to-image AI models grow more sophisticated and easier to use, the volume of such content is only increasing. The escalating problem led Google to announce last week that it will work to filter out these deepfakes in search results, and the Senate recently passed ...

LOGAN, UTAH, USA -- Utah State University geoscientist Alexis Ault recalls the devastating aftermath of back-to-back 7.8 and 7.6-magnitude earthquakes on Feb. 6, 2023, near the Turkey-Syria border that killed more than 50,000 people and displaced millions. “We witnessed the destruction firsthand, as well as the resilience of the country and population trying to get their footing and rebuild,” says Ault, associate professor in USU’s Department of Geosciences, who traveled to the disaster site about six months after ...

Light is an excellent carrier of information used not only for classical communication technologies but also increasingly for quantum applications such as quantum networking and computing. However, processing light signals is far more complex, compared to working with common electronic signals. An international team of researchers including Dr. Olga Kocharovskaya, a distinguished professor in the Department of Physics and Astronomy at Texas A&M University, has demonstrated a novel way of storing and releasing X-ray pulses at the single photon level — a concept first ...

A new study from UC Davis Health could help to increase the supply of donor kidneys. Researchers have found that transplant patients who receive kidneys infected with the parasite toxoplasma have virtually the same outcomes as those who receive toxoplasma-negative organs. Despite longstanding concerns, those who received kidneys from toxoplasma antibody positive donors (TPDs) had almost identical mortality and rejection rates. The research was published in Transplant International. “Organs from donors who were positive for toxoplasma did ...

Offering patients with concussion a type of brain scan known as diffusion tensor imaging MRI could help identify the one in three people who will experience persistent symptoms that can be life changing, say Cambridge researchers. Around one in 200 people in Europe every year will suffer concussion. In the UK, more than 1 million people attend Emergency Departments annually with a recent head injury. It is the most common form of brain injury worldwide. When a patient in the UK presents at an Emergency Department with head injury, they ...

Experiments conducted by UC Merced researchers find that people who perform good deeds are far more likely to be thought of as religious believers than atheists. Moreover, the psychological bias linking kindness and helpfulness with faith appears to be global in scale. Research on the mental link between moral behavior and religious belief goes back more than a decade. Prior research, however, emphasized the dark side of this equation, with participants asked whether they assumed it was more probable that a serial killer believed in God or was an atheist (people in nations all over the planet thought the latter ...

In September 2023, a megatsunami in remote eastern Greenland sent seismic waves around the world, piquing the interest of the global research community. The event created a week-long oscillating wave in Dickson Fjord, according to a new report in The Seismic Record. Angela Carrillo-Ponce of GFZ German Research Centre for Geoscience and her colleagues identified two distinct signals in the seismic data from the event: one high-energy signal caused by the massive rockslide that generated the tsunami, and one very long-period (VLP) signal that lasted over a week. Their analysis of the VLP signal—which was detected as far as 5000 kilometers away—suggests ...

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.  Now, researchers at the Broad Institute of MIT and Harvard have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable ...

NEW YORK, NY (Aug. 8, 2024) -- Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene’s code affect health. This linear rule of life was thought to govern all forms of life—from humans down to bacteria. But a new study by Columbia researchers shows that bacteria break that rule and can create free-floating and ephemeral genes, raising the possibility that similar genes exist outside ...

STARKVILLE, Miss.—NASA is awarding a Mississippi State University assistant professor a $1.13 million grant to develop a new simulation tool to aid the design of hypersonic vehicles used in space exploration. Vilas Shinde of MSU’s Department of Aerospace Engineering won the grant to develop a new flow stability and transition analysis tool, which will aid researchers and aircraft designers in understanding and predicting changes associated with the boundary layer—air flow in the vicinity of an aircraft’s ...

Houston Methodist researchers have discovered a more accurate and timely way to deliver life-saving drug therapies to the brain, laying the groundwork for more effective treatment of brain tumors and other neurological diseases. In a study published this month in Communications Biology, an open access journal from Nature Portfolio, investigators used an electric field to infuse medicine from a reservoir outside the brain to specific targets inside the brain. This adds a new dimension to the 30-year-old process of injecting therapeutics into the brain through ...

URBANA, Ill. – You’ve probably heard that cultivating gratitude can boost your happiness. But in marriage and families, it’s not just about being more grateful for your loved ones — it’s also important to feel appreciated by them. Researchers at the University of Illinois Urbana-Champaign have previously explored the positive impact of perceived gratitude from romantic partners for couples’ relationship quality. In a new study, they show the benefits of perceived gratitude ...

The Food and Drug Administration (FDA) is tasked with overseeing the safety of the U.S. food supply, setting requirements for nutrition labeling, working with companies on food recalls, and responding to outbreaks of foodborne illness. But when it comes to additives already in our food and the safety of certain ingredients, FDA has taken a hand-off approach, according to a new article in the American Journal of Public Health. The current FDA process allows the food industry to regulate itself when it comes to thousands of added ...

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments. The tool, called Deep Predictor of Binding Specificity (DeepPBS), is a geometric deep learning model designed to predict protein–DNA binding specificity from protein–DNA complex structures. DeepPBS ...

Solid-state electrolytes have been explored for decades for use in energy storage systems and in the pursuit of solid-state batteries. These materials are safer alternatives to the traditional liquid electrolyte—a solution that allows ions to move within the cell—used in batteries today. However, new concepts are needed to push the performance of current solid polymer electrolytes to be viable for next generation materials. Materials science and engineering researchers at the University of Illinois Urbana-Champaign have explored the role of helical secondary structure on the conductivity of solid-state peptide polymer ...