A potential ‘anti-spice’ that could dial down the heat of fiery food
2025-05-22
COLUMBUS, Ohio – If you’ve ever regretted ordering a spicy meal, take note: A new study identifying molecules that suppress the heat of chili peppers hints at the possibility of adapting these compounds into an “anti-spice” condiment for food that’s too fiery to eat.
The research helps explain differences in chili pepper pungency, or spiciness, by identifying three compounds in a range of pepper samples that chemical analysis predicted, and study participants on a tasting panel confirmed, are linked to lower heat intensity.
The findings have multiple potential applications: customized chili pepper breeding, ...
Unravelling the origin of mysterious radiation
2025-05-22
The universe is full of cosmic radiation that can be measured here on Earth.
This cosmic radiation consists of –- produced by black holes, gigantic supernovae, or rotating neutron stars – a type of dead star. These particles contain energy.
Sometimes, however, cosmic rays have a much higher energy than usual. We have known about this since 1962, but we still don’t know why.
We also don’t know where this ultra-high-energy cosmic radiation comes from. Or do we?
Supermassive ...
Why we trust people who grew up with less
2025-05-22
When deciding whom to trust, people are more likely to choose individuals who grew up with less money over those who went to private schools or vacationed in Europe, according to research published by the American Psychological Association.
"Trust is essential for healthy relationships. Without it, romantic partnerships can fail, workplaces can suffer and social divisions can grow,” said lead researcher Kristin Laurin, PhD, a psychology professor at the University of British Columbia. “But what makes people trust someone in the first place?”
To find out, researchers ran a series of experiments with more than 1,900 participants. They explored whether someone's ...
Sriram Gubbi of NIDDK wins Endocrine Society’s 2025 Endocrine Images Art Competition
2025-05-22
WASHINGTON—Sriram Gubbi, M.D., won the Endocrine Society’s 2025 Endocrine Images Art Competition with his microphotograph of follicular thyroid carcinoma cells titled “The Cosmic Bubble”.
The art competition celebrates the beauty of endocrine science as seen through the lens of a microscope. More than 30 entries were judged by a panel of Society members who based their assessments on the aesthetic value of the images and their significance to endocrine research.
Gubbi is a physician-scientist studying thyroid tumors and other thyroid conditions at the National Institute of Diabetes and Digestive ...
When doctors skip the numbers, patients may misjudge the health risks
2025-05-22
When a physician says a procedure is “rarely risky,” what does that really mean? Although terms like “common” and “unlikely” may sound descriptive enough, experts in medical decision-making suggest that leaving out numbers may be misleading for patients.
In a paper published on April 29 in the Journal of General Internal Medicine, a team of researchers and clinicians explained that patients often overestimate risk estimates, like possible side effects or medical conditions, when given only verbal descriptions. They encourage doctors not to shy away from including numbers, offering a list of five science-backed tricks on how to make those ...
Study: Climate change may make it harder to reduce smog in some regions
2025-05-22
CAMBRIDGE, MA – Global warming will likely hinder our future ability to control ground-level ozone, a harmful air pollutant that is a primary component of smog, according to a new MIT study.
The results could help scientists and policymakers develop more effective strategies for improving both air quality and human health. Ground-level ozone causes a host of detrimental health impacts, from asthma to heart disease, and contributes to thousands of premature deaths each year.
The researchers’ modeling ...
How property owners can work to prevent flooding
2025-05-22
The risk of heavy rainfall and severe flooding increases with climate change. But property owners – regardless of size – often underestimate their own responsibility and are unaware of what preventive measures they can take themselves. In a new scientific article, researchers from Linköping University, Sweden, show how to go about preventive work.
Many property owners believe that it is the municipality’s responsibility to ensure that their houses do not get flooded in heavy rain. However, in many countries, including Sweden, owner-responsibility is a cornerstone of the adaption governance, and property owners ...
Understanding the divide: a deep dive into healthcare in Mongolia
2025-05-22
Mongolia, the world’s second-largest landlocked country, presents a unique healthcare landscape owing to its distinctive geography and historical influences. Nearly half of its population is concentrated in the capital city of Ulaanbaatar, and the remainder is scattered across vast semi-desert areas known as the Gobi Desert. Because of this, Mongolia faces significant challenges in delivering equitable healthcare. On top of this geographical divide, the lingering impact of Soviet and Chinese healthcare models has created a system of stark contrasts—modern facilities abound in ...
Ox-eye daisy, bellis and yarrow: Flower strips with at least two sown species provide 70 percent more natural enemies of pests
2025-05-22
They may look good in the landscape, but are they, in fact, useful? This is a subject of frequent debate. In recent years, flower strips along fields and ditches have become popular both in Denmark and abroad. One of the purposes of the strips is to attract more predatory insects that can naturally control pests in the fields, rather than relying on pesticides. The EU aims to reduce pesticide use by 50 percent by 2030.
A meta-analysis from the University of Copenhagen shows that flower strips are effective. At least if they have two or more flower species. ...
How modern dog ownership has redefined family and parenting
2025-05-22
Birth rates are declining worldwide, while dog parenting practices are gaining popularity. What does this growing “furry children” trend reveal about our societies? Researchers from Eötvös Loránd University suggest that, while dogs do not actually replace children, they may, in some cases, offer an opportunity to fulfil a nurturing drive similar to parenting, but with fewer demands than raising biological offspring. Their review, published in European Psychologist, also examines how the shifting roles of dogs within modern family structures are influenced by individual circumstances, but also by cultural norms.
Many wealthy and developed countries—including ...
Green ammonia powered by sunlight
2025-05-22
Ammonia is a chemical essential to many agricultural and industrial processes, but it’s mode of production comes with an incredibly high energy cost. Various attempts have, and are, being made to produce ammonia more efficiently. For the first time, a group including researchers from the University of Tokyo combined atmospheric nitrogen, water and sunlight, and using two catalysts, produced sizable quantities of ammonia without a high energy cost. Their processes mirror natural processes found in plants utilizing ...
How cholera bacteria outsmart viruses
2025-05-22
When we think of cholera, most of us picture contaminated water and tragic outbreaks in vulnerable regions. But behind the scenes, cholera bacteria are locked in a fierce, microscopic war—one that could shape the course of pandemics.
Cholera bacteria aren’t just battling antibiotics and public health measures—they are also constantly under attack from bacteriophages (phages), viruses that infect and kill bacteria. These viruses don’t just influence individual infections; they can make or break entire epidemics. In fact, certain bacteriophages ...
Scientists reveal surface structure of lipid nanoparticles that could improve vaccine and drug delivery
2025-05-22
Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues.
A team led by scientists at the University of Nottingham’s School of Pharmacy demonstrated a new cryogenic mass spectrometry approach for depth profiling frozen tiny lipid nanoparticles to reveal the layers and orientation of the constituent molecules. The findings have been published today in Nature’s Mass Spectrometry Method Development collection.
Lipid nanoparticles (LNP’s) came to ...
Microwave technologies give hummus longer shelf life, eliminate preservatives
2025-05-22
PULLMAN, Wash. — Washington State University scientists are using microwave technology to extend the shelf life of hummus while eliminating the need for chemical preservatives, as demonstrated in a recent Journal of Food Process Engineering paper.
The Middle Eastern dip, which is growing in popularity around the world, was associated with 20 illness outbreaks in the U.S. between 2000 and 2018 that resulted in 65 hospitalizations and five deaths. Because of those outbreaks, many commercial hummus makers use chemical preservatives ...
ATN biomarker dataset now available on the EPND Hub – advancing research into Alzheimer’s disease, Parkinson’s disease, and Dementia with Lewy Bodies
2025-05-22
The European Platform for Neurodegenerative Diseases (EPND) is proud to announce the release of the ATN dataset from its first biomarker case study, now accessible via the EPND Hub. This marks a major step forward in collaborative, cross-disease research tackling neurodegenerative conditions that affect millions across Europe. The release underlines EPND’s mission to foster data and biosample sharing to accelerate breakthroughs in neurodegenerative disease research.
A multi-cohort dataset to study shared disease mechanisms
The biomarker case study builds on the invaluable contributions of cohort investigators and research teams who provided biosamples ...
Frequent large-scale wildfires are turning forests from carbon sinks into super‑emitters
2025-05-22
Richmond Hill, Canada – 6 May 2025 — Forests once hailed as reliable carbon sinks are rapidly becoming “super‑emitters” as record‑breaking wildfires sweep boreal, Amazonian, and Australian landscapes. Today’s climate policies and voluntary carbon markets seldom account for the sharp rise in fire‑driven emissions. A new publication by the United Nations University Institute for Water, Environment and Health (UNU‑INWEH), Beyond Planting Trees: Taking Advantage of Satellite Observations to Improve Forest Carbon Management and Wildfire Prevention, warns about the unintended consequences of current ...
In vitro cancer model reveals how tumor cells access the bloodstream
2025-05-22
Tokyo, Japan – Tumors are made up of millions of cells, and removing all of these cells surgically or eliminating them with medication becomes much more difficult after the cancer has spread to other parts of the body.
Now, in a study published this month in iScience, an interdisciplinary team comprising researchers from the Institute of Industrial Science, The University of Tokyo, Kanazawa University, Institute of Science Tokyo, and Kyorin University School of Medicine has determined exactly how these tumor cells are able to accomplish intrabody travel to form tumors elsewhere.
Small clusters of circulating tumor cells, which are cells that detach from tumors ...
Fine-tuning osteoclast development: a targeted approach to bone disease
2025-05-22
Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often result from the dysregulation of osteoclasts—specialized cells responsible for breaking down bone tissue. Today, many promising treatments target the receptor activator of nuclear factor kappa B ligand (RANKL)-RANK-tumor necrosis factor receptor-associated factor 6 (TRAF6) signaling pathway, which controls ...
New insights into migraine-related light sensitivity
2025-05-22
Knowing the molecule behind light sensitivity in migraines could open the door to better treatments
Scientists in the UK, Australia and China have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia), a common and debilitating symptom of migraines. Their findings, published in The Journal of Headache and Pain, highlight how this molecule affects the brain's pain response, contributing to the uncomfortable reaction to light that's common during migraines.
NEAT1 belongs to a group of molecules known as long noncoding RNAs. Unlike most RNA, which carries instructions for making ...
Positive mindset about ageing in over-60s linked to better recovery after a fall
2025-05-22
There is a strong association between an older person’s view of how they are ageing and how well they will physically recover after a fall.
That is the finding of a new research study from Imperial College London and Coventry University, which is the first to suggest how important psychological factors may be in post-fall physical recovery. The study is published in the Journal of the American Geriatrics Society.
Falls in older adults are a major health concern because they can lead to high levels of physical disability and hospitalisation, as well as affecting people’s ability to live independently. The consequences of falls in older ...
The Lancet: Additional imaging techniques detect early stage cancers missed by mammograms in women with dense breasts, finds trial
2025-05-21
The Lancet: Additional imaging techniques detect early stage cancers missed by mammograms in women with dense breasts, finds trial
In women with dense breasts (breasts with relatively low levels of fatty tissue) and a negative mammogram, supplemental imaging techniques detect early-stage cancers, with imaging techniques three times more effective than ultrasound, finds a phase 3 randomised control trial published in The Lancet.
Women with extremely dense breasts, about 10% of those aged 50-70 years in the UK, face a fourfold increased ...
Antidepressant withdrawal symptoms more common among long-term users
2025-05-21
People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study led by UCL researchers.
Long-term users also tend to experience worse withdrawal symptoms, and for a longer period of time, than short-term users, and are less likely to be able to stop taking the drug when they attempt to do so, according to the findings published in Psychiatry Research.
The study’s lead author Dr Mark Horowitz, visiting clinical researcher at UCL Division of Psychiatry, said: “Our findings confirm what many researchers ...
Illinois study: Novel AI methodology improves gully erosion prediction and interpretation
2025-05-21
URBANA, Ill. – Gully erosion is the most severe form of soil erosion, and it can seriously impact agricultural fields, contributing to sediment loss and nutrient runoff into waterways. Gullies can be triggered suddenly by a single heavy rainfall event, creating deep channels that are difficult to rehabilitate even with heavy machinery. Accurately predicting where gully erosion is likely to occur allows agricultural producers and land managers to target their conservation efforts more effectively.
In a new study, University of Illinois Urbana-Champaign researchers use a new AI-driven approach that combines machine learning with an interpretability ...
Urban areas have higher rates of high-dose opioid prescriptions
2025-05-21
Researchers from the University of Missouri School of Medicine have shed light on what populations are more likely to be prescribed a high dose of opioid medication. This increases their risk of developing opioid use disorder.
Opioids like hydrocodone or oxycodone are typically prescribed to relieve intense pain. A prescription can become an addiction; side effects include building a tolerance to the medication – so the patient has to take a higher dose to feel relief – or becoming physically dependent on the drug. These ...
Lotions, perfumes curb potentially harmful effects of human oxidation field, study finds
2025-05-21
Irvine, Calif., May 21, 2025 — In a paper published today in Science Advances, researchers at the University of California, Irvine, Germany’s Max Planck Institute for Chemistry, Pennsylvania State University and other international institutions report that the application of personal care products such as fragrances and body lotions suppresses a potentially unhealthy “human oxidation field” that exists around our bodies.
This zone, which was the subject of a paper by the same team published in Science in 2022, is created when oils and fats on skin react with ozone, an important oxidant in the indoor environment. ...
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