Recent research shows that people are more likely to take "microbreaks" at work on days when they're tired - but that's not a bad thing. The researchers found microbreaks seem to help tired employees bounce back from their morning fatigue and engage with their work better over the course of the day. At issue are microbreaks, which are short, voluntary and impromptu respites in the workday. Microbreaks include discretionary activities such as having a snack, chatting with a colleague, stretching or working on a crossword puzzle. "A microbreak is, by definition, short," says Sophia Cho, co-author of a paper on the work and an assistant professor ...

RESEARCH TRIANGLE PARK, N.C. -- Joint Army- and Air Force-funded researchers have taken a step toward building a fault-tolerant quantum computer, which could provide enhanced data processing capabilities. Quantum computing has the potential to deliver new computing capabilities for how the Army plans to fight and win in what it calls multi-domain operations. It may also advance materials discovery, artificial intelligence, biochemical engineering and many other disciplines needed for the future military; however, because qubits, the fundamental building blocks of quantum computers, are intrinsically fragile, a longstanding barrier to quantum computing has been effective implementation of quantum error correction. Researchers at University of Massachusetts Amherst, ...

Corporate strategies should be as unique as possible, in fact highly specific to each individual company. This enables companies to compete successfully in the long term. However, the capital market and others, including analysts, often react negatively to the idea of unique strategies. The reason is that deviating from typical industry standards makes them more complex to evaluate. This regularly discourages companies from focusing on unique strategies, even though they would be beneficial for the company in the long term. This contradiction is known as the "uniqueness paradox". A research team from the Universities of Göttingen and Groningen has investigated the influence of different types of investors on the extent of the paradox and thus on the choice of unique strategies. The results ...

Higher progesterone level is protective in mild traumatic brain injury Blood flow in brain is linked to progesterone and stress symptom levels Most concussion research has been focused on male athletes CHICAGO --- Could birth control pills help young female athletes recover faster from concussions and reduce their symptoms? A new Northwestern Medicine pilot study has shown when a female athlete has a concussion injury during the phase of her menstrual cycle when progesterone is highest, she feels less stress. Feeling stressed is one symptom of a concussion. Feeling less stressed is a marker of recovery. The study also revealed for the first time the physiological reason for the neural protection is increased ...

New research from the University of Florida Warrington College of Business finds that feeling psychologically powerful makes leaders' jobs seem more demanding. And perceptions of heightened job demands both help and hurt powerful leaders. Trevor Foulk of the University of Maryland Robert H. Smith School of Business and Klodiana Lanaj, Martin L. Schaffel Professor at UF, note that while power-induced job demands are key to helping leaders more effectively pursue their goals and feel that their jobs are meaningful each day at work, these demands can also cause pain and discomfort, felt in the evening at home. "Power is generally considered a desirable thing, as leaders often seek power, and it's very rare for leaders to turn powerful roles down," Foulk said. "However, this view is qualified ...

WASHINGTON, March 16, 2021 -- Sea-based fish farming systems using net pens are hard on the environment and the fish. A closed cage can improve fish welfare, but fresh seawater must be continuously circulated through the cage. However, ocean waves can cause this circulating water to slosh inside the cage, creating violent motions and endangering the cage and the fish. A study using a scale-model fish containment system is reported in Physics of Fluids, by AIP Publishing. The study shows why violent sloshing motions arise and how to minimize them. Gentle currents can be artificially maintained inside cylindrical closed cages developed for salmon farming. The current is produced by injecting seawater through ...

WASHINGTON, March 16, 2021 -- As Europe experienced its enormous second wave of the COVID-19 disease, researchers noticed the mortality rate -- progression from cases to deaths -- was much lower than during the first wave. This inspired researchers from the University of Sydney and Tsinghua University to study and quantify the mortality rate on a country-by-country basis to determine how much the mortality rate from the second wave decreased from the first. In Chaos, by AIP Publishing, Nick James, Max Menzies, and Peter Radchenko introduce methods to study the progression of COVID-19 cases to deaths during the pandemic's different waves. Their methods involve applied mathematics, specifically nonlinear dynamics, and time series analysis. "We take a time series, ...

Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so. Scientists everywhere can use the model to identify new treatment options for patients with tear gland disorders, such as dry eye disease. Hopefully in the future, the organoids can even be transplanted into patients with non-functioning tear glands. The results will be published in Cell Stem Cell on the 16th of March. The tear gland is located in the upper part of the eye socket. It secretes tear fluid, which is essential for lubrication and nutrition of the cornea and has antibacterial components. Rachel Kalmann ...

Like a well-trained soldier, a white blood cell uses specialized abilities to identify and ultimately destroy dangerous intruders, including creating a protrusion to effectively reach out, lock-on, probe, and possibly attack its prey. Researchers reporting March 16 in Biophysical Journal show in detail that these cells take seconds to morph into these highly rigid and viscous defensive units. Senior author Julien Husson (@_julienhusson), a biophysicist at École Polytechnique near Paris, and collaborators showed previously that certain white blood cells, called T cells, ...

WASHINGTON, March 16, 2021 -- Men and women are impacted differently by brain diseases, like Alzheimer's disease and Parkinson's disease. Researchers are urging their colleagues to remember those differences when researching treatments and cures. In APL Bioengineering, by AIP Publishing, University of Maryland scientists highlight a growing body of research suggesting sex differences play roles in how patients respond to brain diseases, as well as multiple sclerosis, motor neuron disease, and other brain ailments. That is progress from just a few years ago, said Alisa Morss ...

Stem-cell-derived organoids that swell up with tears could shed light on the biology of crying and dry-eye disease, suggests a study publishing March 16 in the journal Cell Stem Cell. Although regenerative therapies using human tear-gland organoids will not be possible anytime soon, these researchers have demonstrated that the organoids can engraft, integrate, and produce mature tear products upon transplantation into mouse tear glands. "We hope that scientists will use our model to identify new treatment options for patients with tear-gland disorders by either testing new drugs on a patient's organoids or expanding healthy cells and, one day, using them for transplantation," says senior study author Hans Clevers (@HansClevers) of the Hubrecht Institute. The ...

Wealthier northeastern US states and Western European countries tended to have significantly lower mortality rates during second-wave COVID-19 infections, new research from the University of Sydney and Tsinghua University has shown. However, the pattern was not as general as expected, with notable exceptions to this trend in Sweden and Germany. Researchers say mortality change could have several explanations: European first-wave case counts were underestimated; First-wave deaths disproportionately affected the elderly; Second-wave infections tended to affect younger people; With some ...

WASHINGTON, March 16, 2021 -- Cancerous cells exhibit several key differences from healthy cells that help identify them as dangerous. For instance, the pH -- the level of acidity -- within a cancerous cell is not the same as the pH within a healthy cell. Researchers from the National University of Singapore developed a method of using machine learning to determine whether a single cell is cancerous by detecting its pH. They describe their work in the journal APL Bioengineering, from AIP Publishing. "The ability to identify single cells has acquired a paramount importance in the field of precision and personalized medicine," ...

What The Study Did: The findings of this study suggest that, based on a sample from an otherwise healthy population, the overall number of SARS-CoV-2 infections in the U.S. may be substantially higher than estimates based on public health case reporting. Authors: Robert L. Stout, Ph.D., of Clinical Reference Laboratory Inc. in Lenexa, Kansas, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.1552) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, ...

What The Study Did: Researchers examined nursing homes in communities with the highest COVID-19 prevalence to identify characteristics associated with resident infection rates. Authors: Hye-Young Jung, Ph.D., of Weill Cornell Medical College in New York, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.1555) Editor's Note: The article includes funding/support disclosures. Please see the article for additional information, including ...

The first systematic study of its kind describes how human viruses including SARS-CoV-2 are better adapted to infecting certain types of tissues based on their ability to hijack cellular machinery and protein synthesis. Carried out by researchers at the Centre for Genomic Regulation (CRG), the findings could help the design of more effective antiviral treatments, gene therapies and vaccines. The study is published today in the journal Cell Reports. Living organisms make proteins inside their cells. Each protein consists of single units of amino acids which are stitched together according to instructions encoded within DNA. The basic units of these instructions are known as a codons, each of which corresponds ...

When scientists at the Institute of Science and Technology (IST) Austria looked at developing zebrafish embryos, they observed an abrupt and dramatic change: within just a few minutes, the solid-like embryonic tissue becomes fluid-like. What could cause this change and, what is its role in the further development of the embryo? In a multidisciplinary study published in the journal Cell, they found answers that could change how we look at key processes in development and disease, such as tumor metastasis. To learn more about how a tiny bunch of cells develops into complex systems ...

CAMBRIDGE, MA -- In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now discovered a mechanism that helps explain whether this damage will lead to cancer in mice: The key is the way cellular DNA repair systems respond. The team found that too little activity of one enzyme necessary for DNA repair leads to much higher cancer rates, while too much activity can produce tissue damage, especially in the liver, which can be fatal. Activity ...

Several oceans' worth of ancient water may reside in minerals buried below Mars' surface, report researchers. The new study, based on observational data and modeling, shows that much of the red planet's initial water - up to 99% - was lost to irreversible crustal hydration, not escape to space. The findings help resolve the apparent contradictions between predicted atmospheric loss rates, the deuterium to hydrogen ratio (D/H) of present-day Mars and the geological estimates of how much water once covered the Martian surface. Ancient Mars was a wet planet - dry riverbeds and relic shorelines record a time when vast volumes of liquid water flowed across the surface. Today, ...

Birds breathe with greater efficiency than humans due to the structure of their lungs--looped airways that facilitate air flows that go in one direction--a team of researchers has found through a series of lab experiments and simulations. The findings will appear Fri., March 19 in the journal Physical Review Letters (to be posted between 10 and 11 a.m. EDT). The study, conducted by researchers at New York University and the New Jersey Institute of Technology, also points to smarter ways to pump fluids and control flows in applications such as respiratory ventilators. "Unlike the air flows deep in the branches of our lungs, which oscillate back and forth as we breathe in and out, the flow moves in a single direction in ...

PHILADELPHIA - Imposter syndrome is a considerable mental health challenge to many throughout higher education. It is often associated with depression, anxiety, low self-esteem and self-sabotage and other traits. Researchers at the Sidney Kimmel Medical College at Thomas Jefferson University wanted to learn to what extent incoming medical students displayed characteristics of imposter syndrome, and found that up to 87% of an incoming class reported a high or very high degree of imposter syndrome. "Distress and mental health needs are critical issues among medical ...

PITTSBURGH (March 16, 2021) ... During the swarming of birds or fish, each entity coordinates its location relative to the others, so that the swarm moves as one larger, coherent unit. Fireflies on the other hand coordinate their temporal behavior: within a group, they eventually all flash on and off at the same time and thus act as synchronized oscillators. Few entities, however, coordinate both their spatial movements and inherent time clocks; the limited examples are termed "swarmalators"1, which simultaneously swarm in space and oscillate in time. Japanese tree frogs are exemplar swarmalators: each frog changes both its location and rate of croaking ...

How much do people have to pay for a travel permit to another country? A research team from Göttingen, Paris, Pisa and Florence has investigated the costs around the world. What they found revealed a picture of great inequality. People from poorer countries often pay many times what Europeans would pay. The results have been published in the journal Political Geography. Dr Emanuel Deutschmann from the Institute of Sociology at the University of Göttingen, together with Professor Ettore Recchi, Dr Lorenzo Gabrielli and Nodira Kholmatova (from Sciences Po Paris, CNR-ISTI Pisa and EUI Florence respectively) compiled a new dataset on visa costs for travel between countries worldwide. The analysis shows that on average people ...

COLUMBUS, Ohio - The link between psychological stress and physical health problems generally relates to a stress-induced immune response gone wild, with inflammation then causing damage to other systems in the body. It's a predictable cascade - except in pregnancy, research suggests. Scientists exploring the negative effects of prenatal stress on offspring mental health set out to find the immune cells and microbes in stressed pregnant mice most likely to trigger inflammation in the fetal brain - the source for anxiety and other psychological problems identified in previous research. Instead, the researchers found two simultaneous conditions ...

Wearable electronic devices like fitness trackers and biosensors, are very promising for healthcare applications and research. They can be used to measure relevant biosignals in real-time and send gathered data wirelessly, opening up new ways to study how our bodies react to different types of activities and exercise. However, most body-worn devices face a common enemy: heat. Heat can accumulate in wearable devices owing to various reasons. Operation in close contact with the user's skin is one of them; this heat is said to come from internal sources. Conversely, when a device is worn outdoors, sunlight acts as a massive external source of heat. These sources combined can easily raise the temperature ...