“[...] we demonstrated that the combination of Nerofe and DOX exerts a synergistic effect during mCRC treatment [...]” BUFFALO, NY- July 5, 2023 – A new research paper was published in Oncotarget's Volume 14 on July 1, 2023, entitled, “Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin.” Members of the rat sarcoma viral oncogene (RAS) subfamily KRAS are frequently mutated oncogenes in human cancers and have been identified ...

A new study conducted by researchers at Bar-Ilan University in Israel has shed light on the long-term impact of COVID-19 on the quality of life among different ethnic groups in the country. The study, part of a larger cohort project, highlights a significant discrepancy between Arabs and Druze, and Jews, with the two former groups experiencing a more pronounced decline in quality of life one year after infection.   In this cohort study, researchers regularly followed up with individuals who had been infected with the SARS-CoV-2 virus to assess various aspects of their health. The findings, published in the International ...

Every bird you’ve ever seen— every robin, every pigeon, every penguin at the zoo— is a living dinosaur. Birds are the only group of dinosaurs that survived the asteroid-induced mass extinction 66 million years ago. But not all the birds alive at the time made it. Why the ancestors of modern birds lived while so many of their relatives died has been a mystery that paleontologists have been trying to solve for decades. Two new studies point to one possible factor: the differences between how modern birds and their ancient cousins molt their feathers. Feathers are one of the key traits that all birds share. They're made of a protein called keratin, the same material ...

“[...]  the results suggest a possible novel approach [for] exploring skin disorders [...]” BUFFALO, NY- July 5, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, “A novel peptide ‘T14’ reflects age and photo-aging in human skin.” T14 is a 14mer peptide derived from the C-terminus of acetylcholinesterase (AChE). Once cleaved, it is independently bioactive of the parent molecule and enhances calcium influx in different cell types, in a range of scenarios: it binds to an allosteric site selectively ...

There has been much buzz about the warming planet’s melting Arctic region opening shipping routes and lengthening travel seasons in ocean passageways that ice once blocked. Expanded fishing, trade and tourism is envisioned. Operative word: Envisioned. Scientists at Michigan State University (MSU), University of Waterloo, and University of Alaska Fairbanks report in Climatic Change where vessels are traveling in the ice-covered waters of the Arctic between Alaska and Russia, and what those reports may mean for important wildlife and communities in the region. “Even with climate change, sea ice is still a substantial barrier to Arctic vessel traffic,” said Kelly Kapsar, ...

AUSTIN, Texas — As public concerns mount over lack of transparency in political giving, a new study from researchers at The University of Texas at Austin is the first to illuminate how and why corporations choose to legally conceal their lobbying and campaign contributions. U.S. companies are required to disclose the total amount they spend on political activity, but beyond that, the disclosure is incredibly vague, according to Tim Werner, associate professor of business, government and society at the McCombs ...

WASHINGTON (July 5, 2023)--Although the situation is improving, Latinos and especially Mexican Americans, remain very underrepresented in U.S. health professions that require advanced degrees, according to a study published today in the journal Health Affairs. The study by George Washington University researchers is the first to examine the representation of the four largest Latino populations in the U.S. health workforce and the findings raise concerns about the lack of diversity in the U.S. health workforce. The study ...

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, JULY 5, 2023 MINNEAPOLIS – Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer’s disease and related dementias compared to people who have steady levels, according to new research published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia. “Prevention strategies for Alzheimer’s and related dementias are urgently needed,” ...

Amid heightened demand for mental health care, a new study finds that nearly two-thirds of Medicare Advantage psychiatrist networks contain less than 25% of all psychiatrists in a given service area. “This means that many people who have coverage through Medicare Advantage plans may not actually have access to psychiatrists, given how few are considered in-network,” said lead author Jane Zhu, M.D., assistant professor of medicine (general internal medicine and geriatrics) in the School of Medicine at Oregon Health & Science University. The research published today in the July issue of the journal Health Affairs. Medicare is the federal ...

ATLANTA, July 5, 2023 – More people with advanced cancers in the United States received critical palliative care services, according to new findings by researchers at the American Cancer Society (ACS). Palliative care includes supportive care managed by a healthcare team, such as relief from symptoms, pain, and stress. Researchers also found where a patient lives in the U.S. may determine their use of palliative care. Medicaid expansion under the ACA was associated with the largest increases in palliative care use. The study was published today in the July issue of the journal Health Affairs. “Our findings are encouraging, especially with growing evidence of the important ...

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, JULY 5, 2023 MINNEAPOLIS – Taking good care of your teeth may be linked to better brain health, according to a study published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that gum disease and tooth loss were linked to brain shrinkage in the hippocampus, which plays a role in memory and Alzheimer’s disease. The study does not prove that gum disease or tooth loss causes Alzheimer’s disease; it only shows an association. “Tooth ...

July 5, 2023-- Health departments have a historic opportunity to bolster their workforce due to new funding but often do not have accurate or updated job descriptions or short, attention-grabbing job postings to use as marketing tools for recruitment. New research by Columbia University Mailman School of Public Health will help lead to evidence-based job descriptions and postings that health departments can now use. The study is the first attempt to compile existing occupation-specific job task analyses, lists of competencies, and certifications across multiple job types within governmental public health that can allow comparisons of ...

AMHERST, Mass. – Computer scientists at the University of Massachusetts Amherst recently found that data-visualization experts have no agreed-upon understanding of who makes up one of their largest audiences—novice users. The work, which recently won a coveted Best Paper Award at the Association for Computing Machinery’s conference on Human Factors in Computing Systems (ACM CHI), is an important first step in ensuring more inclusive data visualizations, and thus data visualization that works for all users. Data visualization is the representation of data in a ...

Malaria remains one of the world’s deadliest diseases. Each year malaria infections result in hundreds of thousands of deaths, with the majority of fatalities occurring in children under five. The Centers for Disease Control and Prevention recently announced that five cases of mosquito-borne malaria were detected in the United States, the first reported spread in the country in two decades. Fortunately, scientists are developing safe technologies to stop the transmission of malaria by genetically editing mosquitoes that spread the parasite that causes the disease. Researchers at the University of California San Diego led by Professor Omar Akbari’s laboratory have engineered ...

The Jackson Laboratory has won the 2023 Plan Sponsor of the Year award in the “Nonprofit Defined Contribution Plans $300 Million and Greater” category. The annual Plan Sponsor of the Year award is presented by PLANSPONSOR magazine, a professional publication that focuses on retirement programs. The award recognizes retirement plan sponsors that show a commitment to their participants’ financial health and retirement success. Winners were announced at the PLANSPONSOR National Conference in Orlando, Fla. on June 21. “Benefits such as ...

When asked to draw their local wildlife, 401 UK schoolchildren aged 7 to 11 most commonly drew mammals and birds, while amphibians and reptiles appeared in the fewest drawings, suggesting imbalances in children’s ecological awareness. Kate Howlett and Edgar Turner of the University of Cambridge, UK, present these findings in the open-access journal PLOS ONE on July 5, 2023. Prior research has shown that, overall, European and North American children’s access to green space has declined in recent decades, and they are becoming increasingly disconnected from nature. Access ...

Body mass index (BMI) may not increase mortality independently of other risk factors in adults, according to a new study published this week in the open-access journal PLOS ONE by Aayush Visaria and Soko Setoguchi of Rutgers University, US. The prevalence of overweight and obesity has risen dramatically over the last 25 years, and it is well-established that elevated BMI can contribute to several cardio-metabolic conditions. However, studies that have analyzed the association between BMI and all-cause mortality have been inconsistent. Most US studies have used data from the 1960s through 1990s and have included predominantly non-Hispanic White adults.  In the new work, the researchers ...

A study conducted at a retirement home in South Africa suggests that programs promoting interaction between residents and children may provide mental health benefits and could help manage common mental health conditions, such as anxiety and depression. Elizabeth Jane Earl and Debbie Marais of Stellenbosch University, South Africa, present these findings in the open-access journal PLOS ONE on July 5, 2023. Prior research suggests that common mental health conditions are often undiagnosed and untreated in retirement homes. Standard treatment for such conditions typically involves a combination of medication and non-pharmacological ...

The profile of scent compounds from a person’s hand can be used to predict their sex, according to a new study led by Kenneth Furton of Florida International University, publishing July 5 in the open-access journal PLOS ONE. In criminal investigations, dogs have long been used to reliably identify and track people based on their odor. But while human scent evidence from the field is well established, researchers have made little progress in analyzing human scent profiles in the lab. In the new study, researchers used an analysis technique called mass spectrometry to analyze ...

LA JOLLA, CALIF. – July 05, 2023 – New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune cells is also active inside melanoma cells, helping promote tumor growth. The findings, published in the journal Science Advances, suggest that targeting this protein with new drugs may deliver a powerful double hit to melanoma tumors. “The ...

A study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury and those without TBI. The study suggests depression after TBI may not be the same as depression related to other causes. A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional ...

Billions of years ago, in the giant disk of dust, gas, and rocky material that orbited our young sun, larger and larger bodies coalesced to eventually give rise to the planets, moons, and asteroids we see today. Scientists are still trying to understand the processes by which planets, including our home planet, were formed. One way researchers can study how Earth formed is to examine the magmas that flow up from deep within the planet’s interior. The chemical signatures from these samples contain a record of the timing and the nature of the materials that came together to form ...

University of Queensland researchers have optimised a new technique to help forecast how volcanoes will behave, which could save lives and property around the world. Dr Teresa Ubide from UQ’s School of the Environment and a team of international collaborators have trialled a new application of the tongue-twisting approach: laser ablation inductively coupled plasma quadruple mass spectrometry. “It’s a mouthful, but this high-resolution technique offers clearer data on what’s chemically occurring within a volcano’s magma, which is fundamental to forecasting eruption patterns and changes,” Dr Ubide said. She described magma ...

New device shows promise in small animal studies Not only can it restore normal heart rhythms, it also can show which areas of the heart are functioning well and which areas are not After the device is no longer needed, it harmlessly dissolves inside the body, bypassing the need for extraction EVANSTON, Ill. — Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event. To help prevent those deaths, researchers at Northwestern ...

A team of astrophysicists at the University of Toronto (U of T) has revealed how the slow and steady lengthening of Earth’s day caused by the tidal pull of the moon was halted for over a billion years.  They show that from approximately two billion years ago until 600 million years ago, an atmospheric tide driven by the sun countered the effect of the moon, keeping Earth’s rotational rate steady and the length of day at a constant 19.5 hours.   Without this billion-year pause in the slowing of our planet’s rotation, our current 24-hour day would stretch to over 60 hours.  The ...