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The chemistry of magnesium turned on its head

2021-05-14
The international scientific community agrees that the latest findings of an FAU research team will revolutionise the entire chemistry of magnesium. The research team have discovered magnesium, which usually has a double positive charge in chemical compounds, in the elemental zero-oxidation state. They have published their ground-breaking findings in the journal Nature. In the periodic table of elements, magnesium (Mg) is a metal with low electronegativity, which means it does not easily attract electrons but easily loses both the electrons in its outer shell during chemical reactions. It therefore only exists in nature as a compound ...

Hanging by a thread: Imaging and probing chains of single atoms

Hanging by a thread: Imaging and probing chains of single atoms
2021-05-14
Ishikawa, Japan - Today, many well-studied materials in various fields, such as electronics and catalysis, are close to reaching their practical limits. To further improve upon modern technology and outperform state-of-the-art devices, researchers looking for new functional materials have to push the boundaries and explore more extreme cases. A clear example of this is the study of low-dimensional materials, such as monoatomic layers (2D materials) and monoatomic chains (1D materials). It has been proved time and time again that low-dimensional materials exhibit exotic properties that are absent in their 3D bulk counterparts. For example, monoatomic chains of metals like gold ...

Where on Earth is all the water?

Where on Earth is all the water?
2021-05-14
High-temperature and high-pressure experiments involving a diamond anvil and chemicals to simulate the core of the young Earth demonstrate for the first time that hydrogen can bond strongly with iron in extreme conditions. This explains the presence of significant amounts of hydrogen in the Earth's core that arrived as water from bombardments billions of years ago. Given the extreme depths, temperatures and pressures involved, we are not physically able to probe very far into the earth directly. So, in order to peer deep inside the Earth, researchers use techniques involving seismic data to ascertain things like composition and density of subterranean material. Something that has stood out for as long as these kinds of measurements have been taking place is that the core is primarily ...

Ecology-inspired mathematical models to understand social networks

2021-05-14
The ease with which anyone can create online content for free, especially on social media, has led to superabundance of information being one of the defining characteristics of today's communication systems. This situation has resulted in increasingly intense competition for attention, which has become a scarce good. The researchers from the Complex Systems group (CoSIN3) at the UOC's Internet Interdisciplinary Institute (IN3) María José Palazzi and Albert Solé --professor at the Faculty of Computer Science, Multimedia and Telecommunications?--, led by Javier Borge, have participated in the design of ...

Less wastage during production of marble slabs in the Roman imperial period than today

Less wastage during production of marble slabs in the Roman imperial period than today
2021-05-14
When it comes to ancient Roman imperial architecture, most people usually have a mental image of white marble statues, columns, or slabs. While it is true that many buildings and squares at that time were decorated with marble, it was frequently not white but colored marble that was employed, such as the green-veined Cipollino Verde, which was extracted on the Greek island of Euboea. Because marble was very expensive, it was often placed in thin slabs as a cladding over other, cheaper stones. "To date, however, no actual remains of marble workshops from the Roman imperial era have been found, so little is known about marble processing during this period," said Professor Cees Passchier ...

Charting the expansion history of the universe with supernovae

Charting the expansion history of the universe with supernovae
2021-05-14
An international research team analyzed a database of more than 1000 supernova explosions and found that models for the expansion of the Universe best match the data when a new time dependent variation is introduced. If proven correct with future, higher-quality data from the Subaru Telescope and other observatories, these results could indicate still unknown physics working on the cosmic scale. Edwin Hubble's observations over 90 years ago showing the expansion of the Universe remain a cornerstone of modern astrophysics. But when you get into the details ...

Nagoya University scientists reveal unprecedentedly versatile new DNA staining probe

Nagoya University scientists reveal unprecedentedly versatile new DNA staining probe
2021-05-14
A group of scientists at Nagoya University, Japan, have developed an incredibly versatile DNA fluorescent dye, named 'Kakshine' after a former NU student of its members, Dr Kakishi Uno, but it also means to make the nucleus shine brightly, since the nucleus is pronounced 'Kaku' in Japanese. Dr Uno, with Dr Yoshikatsu Sato and Nagisa Sugimoto, the other two members of the research team at the Institute of Transformative Bio-Molecules (ITbM), succeeded in developing a DNA binding fluorescent dye with the pyrido cyanine backbone, which satisfied the three principal qualities required of such a dye - that it have high selectivity for DNA, ability to use visible light with limited phototoxicity, ...

New research will improve safety and quality of Heparin

New research will improve safety and quality of Heparin
2021-05-14
A new method to analyse the blood thinning drug Heparin has been developed that can pinpoint contaminants more accurately and quickly, providing greater quality control and safety. An interdisciplinary team from the University of Nottingham's Schools of Pharmacy and Medicine have used the latest chemical imaging technology to identify contaminants in Heparin at the nanoscale, a discovery that manufacturers could use to improve the quality and safety of this widely used anticoagulant drug. The research has been published in Communications Chemistry. Heparin is naturally occurring glycosaminoglycan ...

E-cigarettes associated with wheezing, shortness of breath

2021-05-14
ATS 2021, New York, NY - The use of e-cigarettes is associated with wheezing and shortness of breath in young adults and adolescents, even in those who don't smoke cigarettes or marijuana, according to research presented at the ATS 2021 International Conference. Alayna P. Tackett, PhD, assistant professor of preventive medicine, University of Southern California Keck School of Medicine, and colleagues conducted a web-based survey of 2,931 adolescents and young adults (average age: 18.9) with questions on the use of e-cigarettes, cigarettes and cannabis, along with self-reported asthma diagnosis and respiratory symptoms, over the previous 30 days. The survey was fielded between August 6 and 30, 2020 among a national convenience sample of youth and young ...

Living in redlined areas associated with lower lung function in those with asthma

2021-05-14
ATS 2021, New York, NY - Individuals with asthma who live in redlined neighborhoods have worse lung function than those in locales that excluded Black people and benefited from decades of inequitable wealth accumulation at the expense of Black communities in the United States, according to research presented at the ATS 2021 International Conference. Alexander Schuyler, MD/PhD candidate, University of Pittsburgh School of Medicine, and Sally Wenzel, MD, director, Asthma & Environmental Lung Health Institute, University of Pittsburgh Medical Center, sought to examine the connection between residence in historically ...

Teens, adults who use E-cigarettes have increased odds of asthma, asthma attacks

2021-05-14
Session: TP16 Abstract Presentation Time: Available On-Demand; 8 a.m. EDT, Friday, May 14, 2021 ATS 2021, New York, NY - While vaping is thought to be a safer alternative to smoking, teens and adults who use e-cigarettes have increased odds of developing asthma and having asthma attacks, according to research presented at the ATS 2021 International Conference. Teresa To, PhD, senior scientist in the Child Health Evaluative Sciences program at The Hospital for Sick Children (SickKids), and colleagues sought to determine whether youth and young adults ...

Genes associated with COVID-19 risk identified

2021-05-14
Session: TP91 Abstract Presentation Time: On Demand; 8 a.m. EDT, Friday, May 14, 2021 ATS 2021, New York, NY - Having genetic risk variants in the ABO gene might significantly increase the chances of developing COVID-19, and other genes may also increase COVID-19 risk, according to research presented at the ATS 2021 International Conference. Much about COVID-19 remains a medical mystery, including whether certain genes place individuals at greater risk of contracting the SARS-CoV-2 virus, which causes COVID-19. Ana Hernandez Cordero, PhD, postdoctoral fellow with the Centre for Heart Lung Innovation, University of British Columbia, and colleagues used integrative genomics combined with proteomics to identify ...

How moths find their flame - genetics of mate attraction discovered

How moths find their flame - genetics of mate attraction discovered
2021-05-14
The mysteries of sexual attraction just became a little less mysterious - at least for moths. A team of six American and European research groups including Tufts University has discovered which gene expressed in the brain of the male European corn borer moth controls his preference for the sex pheromone produced by females. This complements a previous study on the gene expressed in the female pheromone gland that dictates the type of blend she emits to attract males. The study was reported today in Nature Communications. The implications go beyond ...

Researchers develop 3D-printed jelly

Researchers develop 3D-printed jelly
2021-05-14
3D-printable gels with improved and highly controlled properties can be created by merging micro- and nano-sized networks of the same materials harnessed from seaweed, according to new research from North Carolina State University. The findings could have applications in biomedical materials - think of biological scaffolds for growing cells - and soft robotics. Described in the journal Nature Communications, the findings show that these water-based gels - called homocomposite hydrogels - are both strong and flexible. They are composed of alginates - chemical compounds found in seaweed and algae that are commonly used as thickening agents and in wound ...

New immunotherapy 'highly effective' against hepatitis B

2021-05-14
Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world. Each year, globally, chronic HBV causes an estimated 880,000 deaths from liver cirrhosis and hepatocellular carcinoma/liver cancer (HCC). The pioneering study used immune cells isolated directly from patient liver and tumour tissue, to show that targeting acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme that helps to manage cholesterol levels in cells*, was highly effective at boosting immune ...

Herbivores developed powerful jaws to digest tougher plants after the mass extinctions

Herbivores developed powerful jaws to digest tougher plants after the mass extinctions
2021-05-14
Researchers at the University of Bristol found that plant eaters diversified quickly after mass extinctions to eat different kinds of plants, and the ones that were able to chew harsher materials, which reflected the drying conditions of the late Triassic, became the most successful. These tougher herbivores included some of the first dinosaurs. Following the largest mass extinction of all time, the end-Permian mass extinction, ecosystems rebuilt from scratch during Triassic times, from 252-201 million years ago paving the way for new species, and many new kinds of plants and animals emerged. In a new study published in Nature Communications and led by Dr Suresh Singh of Bristol's School of Earth Sciences, fresh ...

Health outcomes differ between UK and US children with cystic fibrosis

2021-05-14
A new study led by University of Liverpool researchers has confirmed that children with cystic fibrosis (CF) in the US have better lung function than UK children with the disease. The study suggests that differences do not appear to be explained by early growth or nutrition, but could be linked to differences in the use of early treatments. This long-term analysis follows a 2015 study comparing UK and CF populations in the year 2010, which first highlighted potential differences in lung function. CF is a serious, multi-organ inherited disease characterised by pulmonary infections and progressively declining lung function. Most people ...

Above the noise

Above the noise
2021-05-14
Osaka, Japan - Scientists from the Institute of Scientific and Industrial Research at Osaka University used machine learning methods to enhance the signal-to-noise ratio in data collected when tiny spheres are passed through microscopic nanopores cut into silicon substrates. This work may lead to much more sensitive data collection when sequencing DNA or detecting small concentrations of pathogens. Miniaturization has opened the possibility for a wide range of diagnostic tools, such as point-of-care detection of diseases, to be performed quickly and with very small samples. For example, unknown particles can be analyzed by passing ...

No-one knew if lymph vessel cells bear cilia; turns out, they're indispensable for health

2021-05-14
The primary cilium, an antenna-like subcellular structure ('organelle') protruding from the outside of many types of vertebrate cells, has an important but previously overlooked role in guiding the growth of lymphatic vessels, shows a new study. The authors show for the first time that mouse and human lymphatic endothelial cells (LECs) - which make up the inner and outer lining of lymphatic vessels - use primary cilia. They find that LEC primary cilia may direct the growth of a functional lymphatic network, not only during prenatal development, but also throughout life during inflammation and wound healing and in response to cancer. They show that mice in which the formation of primary cilia in LECs is prevented develop lymphatic ...

Probiotics associated with fewer respiratory symptoms in overweight and older people

2021-05-14
Bethesda, MD (May 14, 2021) -- Daily probiotic use was associated with fewer upper respiratory symptoms in overweight and older people, according to a study that suggests a potential role for probiotics in preventing respiratory infections. The study was selected for presentation at Digestive Disease Week® (DDW) 2021. "This is not necessarily the most intuitive idea, that putting bacteria into your gut might reduce your risk of respiratory infection," said Benjamin Mullish, MD, a lead researcher on the study and clinical lecturer in the Division of Digestive Diseases, Imperial College London, England, "but it's further ...

Pancreatic cancer trials fail to include minorities despite worse outcomes

2021-05-14
Bethesda, MD (May 14, 2021) -- Despite the fact that certain racial and ethnic minorities get pancreatic cancer more often, are diagnosed at a younger age and die sooner, clinical trials fail to include representative proportions of non-White patients at every phase of study, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2021. "We see disparities in representation across all kinds of clinical trials, so we were not surprised to see that it also occurs in pancreatic cancer trials. But hopefully we can make a change in that arena in the future," said Kelly Herremans, MD, lead researcher on the study and surgical research fellow at the University ...

Pairing bariatric procedure with diabetes drug increases weight loss

2021-05-14
Bethesda, MD (May 14, 2021) -- Combining minimally invasive endoscopic sleeve gastroplasty (ESG) with the diabetes drug semaglutide can provide additional significant weight loss for patients who are not candidates for invasive weight-loss surgery, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2021. "As the worldwide obesity rate continues to climb, so do the number of people seeking bariatric surgery to treat their condition," said Anna Carolina Hoff, MD, lead researcher on the study and founder and clinical director of Angioskope Brazil, São José dos Campos. "Surgical procedures are some of the most successful ways to help patients lose weight, but they ...

COVID-19 pandemic sees increased consults for alcohol-related GI and liver diseases

2021-05-14
Bethesda, MD (May 14, 2021) -- Inpatient consults for alcohol-related gastrointestinal (GI) and liver diseases have surged since the beginning of the COVID-19 pandemic and remained elevated, according to research selected for presentation at Digestive Disease Week® (DDW) 2021. The proportion of patients that required inpatient endoscopic interventions for their alcohol-related GI and liver diseases has also increased, highlighting an apparent worsening trend in the severity of disease. "When we went into lockdown, many people experienced significant negative ...

New weapon in the fight against gastrointestinal disease in informal settlements

2021-05-14
Monash University researchers have validated a way to successfully detect a diverse range of bacteria (pathogens) that cause diarrhoeal disease in informal settlements. Better protection from disease for people living in communities facing water, sanitation and hygiene challenges is essential, as microbes that cause gastrointestinal disease (enteropathogens) are responsible for 1.4 million deaths per year, predominantly in children under five, and cause impaired nutrition and development. However, it is highly challenging to effectively monitor their spread due to the sheer number of pathogens and sources involved. Numerous enteropathogens cause diarrhoea and other gastrointestinal diseases, spanning viruses, bacteria, amoeba, and worms, each with distinct characteristics. Moreover, ...

Gimmicky or effective? The effects of imaginative displays on customers' purchase behavior

2021-05-14
Researchers from Monash University, Queensland University of Technology, and Capital University of Economics and Business published a new paper in the Journal of Marketing that examines the effects of imaginative product displays in retail stores on customers' purchase behavior. The study, forthcoming in the Journal of Marketing, is titled "Gimmicky or Effective? The Effects of Imaginative Displays on Customers' Purchase Behavior" and is authored by Hean Tat Keh, Di Wang, and Li Yan. Imaginative displays are constructed using multiple units of the same product in a novel, yet aesthetically appealing, form. Results from six ...
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