DURHAM, N.C. -- Integrating the American classroom has long been a goal of many who seek to eradicate racial discrimination. But a new paper from four economists, including Duke University's William A. "Sandy" Darity Jr., suggests that Black students do not always benefit from attending racially balanced schools. Instead, Black adults who attended racially balanced high schools in the mid-20th century completed significantly less schooling than those who attended either predominantly black or predominantly white schools, the authors found. "Standard wisdom has it that school desegregation paves the way to racial ...

NEW YORK, APRIL 5, 2021 -- Nine of the hottest years in human history have occurred in the last decade. Without a major shift in this climate trajectory, the future of life on Earth is in question. Should humans, whose fossil-fueled society is driving climate change, use technology to put the brakes on global warming? Every month since September 2019 the Climate Intervention Biology Working Group, a team of internationally recognized experts in climate science and ecology, has gathered remotely to bring science to bear on that question and the consequences of geoengineering a cooler ...

SARS-CoV-2 showed the world with devastating clarity the threat undetected viruses can pose to global public health. SpillOver, a new web application developed by scientists at the University of California, Davis, and contributed to by experts from all over the world, ranks the risk of wildlife-to-human spillover for newly-discovered viruses. SpillOver is the first open-source risk assessment tool that evaluates wildlife viruses to estimate their zoonotic spillover and pandemic potential. It effectively creates a watchlist of newly-discovered viruses to help policymakers and health scientists prioritize them for further characterization, surveillance, and risk-reducing interventions. The tool is linked to a study published in the journal PNAS, in which ...

New Haven, Conn. -- In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS). Furthermore, using fully sequenced patient-derived xenografts, the team has preclinically validated new treatment modalities, which may point to new treatments for uterine cancer. Study results were published online in an early edition of the Proceedings of the National Academy of Science (PNAS). Uterine cancer is the most common gynecologic malignancy and uterine leiomyosarcomas (uLMS) are highly lethal sarcomas arising from the myometrium, the smooth muscle layer of the uterus. They represent ...

Overfishing likely did not cause the Atlantic cod, an iconic species, to evolve genetically and mature earlier, according to a study led by Rutgers University and the University of Oslo - the first of its kind - with major implications for ocean conservation. "Evolution has been used in part as an excuse for why cod and other species have not recovered from overfishing," said first author END ...

BOSTON - Men and women whose mothers experienced stressful events during pregnancy regulate stress differently in the brain 45 years later, results of a long-term study demonstrate. In a unique sample of 40 men and 40 women followed from the womb into their mid-forties, the brain imaging study showed that exposure during fetal development to inflammation-promoting natural substances called cytokines, produced by mothers under negative stress, results in sex-associated differences in how the adult brain responds to negative stressful situations more than 45 years after ...

High levels of biodiversity in aquatic settings offers a wide range of vitamins, minerals, and fatty acids crucial for human health, a range of nutrients that are lacking in ecosystems where the number of species have been reduced by overfishing, pollution, or climate change, researchers report April 5 in the journal Proceedings of the National Academy of Sciences. "What we found is that biodiversity is crucial to human health," said Yale's Joey Bernhardt, a G. Evelyn Hutchinson Postdoctoral Fellow in the Department of Ecology and Evolutionary Biology and co-author of the paper. While humans can achieve their protein requirements even with seafood from less-diverse systems, ...

A growing body of evidence suggests that biodiversity loss increases our exposure to both new and established zoonotic pathogens. Restoring and protecting nature is essential to preventing future pandemics. So reports a new Proceedings of the National Academy of Sciences (PNAS) paper that synthesizes current understanding about how biodiversity affects human health and provides recommendations for future research to guide management. Lead author Felicia Keesing is a professor at Bard College and a Visiting Scientist at Cary Institute of Ecosystem Studies. She explains, "There's a persistent myth ...

EAST LANSING, Mich. - Nine of the hottest years in human history have occurred in the past decade. Without a major shift in this climate trajectory, the future of life on Earth is in question, which poses a new question: Should humans, whose fossil fueled society is driving climate change, use technology to put the brakes on global warming? Michigan State University community ecologist Phoebe Zarnetske is co-lead of the Climate Intervention Biology Working Group, a team of internationally recognized experts in climate science and ecology that is bringing science to bear on the question and consequences of geoengineering a cooler Earth. The group's ...

BOSTON - Addiction is associated with social exclusion, loss of access to resources, and general disengagement from civic life. Now, a study recently published in the journal Psychology of Addictive Behaviors and led by David Eddie, PhD, of the Massachusetts General Hospital's Recovery Research Institute has found that the majority of Americans who have resolved an alcohol or other drug problem report achievements related to self-improvement, family engagement, and civic and economic participation since resolving their addiction. Additionally, it appears these achievements accumulate with time in addiction recovery. Incorporating data from the Recovery Research Institute's landmark 2017 National Recovery Study, which indicated ...

A new study by Stanford University biologists finds an explanation for the idea that physical characteristics such as skin pigmentation are "only skin deep." Using genetic modeling, the team has found that when two populations with distinct traits combine over generations, traits of individuals within the resulting "admixed" population come to reveal very little about individuals' ancestry. Their findings were published March 27 in a special edition of the American Journal of Physical Anthropology on race and racism. "When two founding groups first come together, a visible physical trait that differed between those founders initially carries information about the genetic ancestry of admixed individuals," says Jaehee Kim, a postdoctoral research fellow in biology at Stanford and first author ...

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations -- oncogenic RAS or RASV12 -- is also responsible for the regrowth of cancer cells following genotoxic therapy treatment, or drugs that cause damage to a cancer cell's DNA in order to eliminate it from the body. "Most of our knowledge of how cells respond to DNA damage is mainly derived from studies looking at the single cell level," said Yves Chabu, an assistant professor in the MU College of Arts and Science. "Therefore, we don't know much about how tumor cells respond to DNA damage in the broader ...

URBANA, Ill. ¬- If your day started with a cup of coffee, there's a good chance your morning brew came from Colombia. Home to some of the finest Arabica beans, the country is the world's third largest coffee producer. Climate change poses new challenges to coffee production in Colombia, as it does to agricultural production anywhere in the world, but a new University of Illinois study shows effects vary widely depending on where the coffee beans grow. "Colombia is a large country with a very distinct geography. The Andes Mountains cross the country from its southwest to northeast corner. Colombian coffee is currently growing in areas with different altitude levels, and climate impacts will likely be very different for low ...

Pregnancy can increase the risk of morbidity and mortality in women with cardiovascular disease; however, many cardiologists are not having pre-pregnancy contraception discussions with their patients of child-bearing age. There is a need to provide evidence-based guidance for contraceptive safety and effectiveness and pregnancy planning options for this high-risk patient group, according to a paper published in the Journal of the American College of Cardiology (JACC). This paper is one of a five-part JACC focus seminar series addressing a wide range of topics in the emerging cardio-obstetrics field. Prior research has found that 68% of females have had sex at least once by the time they were 17, ...

A recent study proposed a three-dimensional LotusMenu that can "bloom in the palm". With this menu, even if you are not Nezha, you can also control your own lotus. The research paper is titled: "LotusMenu: A 3D Menu using Wrist and Elbow Rotation Inspired by Chinese Traditional Symbol". It's published in SCIENCE CHINA Information Sciences recently, written by Associate Professor Lu Fei's human-computer interaction research team from Beijing University of Posts and Telecommunications. Based on the metaphor of the traditional lotus pattern, the researchers ...

The Bureau of Reclamation today released final technical reports supporting the Water Reliability in the West - 2021 SECURE Water Act Report. Reclamation's 2021 West-Wide Climate and Hydrology Assessment and seven individual basin reports provide detailed information on climate change impacts and adaptation strategies to increase water supply reliability in the West. A new 2021 SECURE Report Web Portal is also available to provide a user-friendly, web-based format for delivery of information in the reports. "Western water supply and delivery systems are affected by changing hydrologic conditions and competing demands," Deputy Commissioner Camille Calimlim Touton said. "These reports highlight Reclamation's effort to use ...

Humans have long explored three big scientific questions: evolution of the universe, evolution of Earth, and evolution of life. Geoscientists have embraced the mission of elucidating the evolution of Earth and life, which are preserved in the information-rich but incomplete geological record that spans more than 4.5 billion years of Earth history. Delving into Earth's deep-time history helps geoscientists decipher mechanisms and rates of Earth's evolution, unravel the rates and mechanisms of climate change, locate natural resources, and envision the future of Earth. Two common approaches, deductive reasoning ...

Researchers from North Carolina State University have developed an exosome-coated stent with a "smart-release" trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue. Angioplasty - a procedure that opens blocked arteries - often involves placing a metal stent to reinforce arterial walls and prevent them from collapsing once the blockage is removed. However, the stent's placement usually causes some injury to the blood vessel wall, which stimulates smooth muscle cells to proliferate and migrate to the site in an attempt to repair the injury. The result is restenosis: a re-narrowing of the blood vessel previously opened by angioplasty. "The ...

ITHACA, N.Y. - The cost of harvesting solar energy has dropped so much in recent years that it's giving traditional energy sources a run for their money. However, the challenges of energy storage - which require the capacity to bank an intermittent and seasonally variable supply of solar energy - have kept the technology from being economically competitive. Cornell University researchers led by Lynden Archer, Dean and Professor of Engineering, have been exploring the use of low-cost materials to create rechargeable batteries that will make energy storage more ...

AMHERST, Mass. - A team of polymer science and engineering researchers at the University of Massachusetts Amherst has demonstrated for the first time that the positions of tiny, flat, solid objects integrated in nanometrically thin membranes - resembling those of biological cells - can be controlled by mechanically varying the elastic forces in the membrane itself. This research milestone is a significant step toward the goal of creating ultrathin flexible materials that self-organize and respond immediately to mechanical force. The team has discovered that rigid solid plates in biomimetic fluid membranes experience interactions ...

Mouse models of neurodevelopmental disorders possess unique, sex-specific metabolic dysfunctions, according to a new study in eNeuro. Understanding the unique metabolic effects of each disorder in both animal models and humans may lead to more personalized treatments and diagnostic methods. Any disorder affecting the brain also impacts the body. People with neurodevelopmental disorders -- including Down syndrome and autism spectrum disorders -- are at increased risk for developing diabetes, obesity, and hypertension. Yet the impact of these three disorders on metabolism has not been studied. Menzies et al. measured the resting energy metabolism of three neurodevelopmental disorder mouse models: Down syndrome, ...

A new report by AARP Pennsylvania and Drexel University's College of Nursing and Health Professions highlights how geographic, racial/ethnic and economic factors are combining to restrict access to health care services for many Pennsylvanians, creating disparities that have become more pronounced during the COVID-19 pandemic. "Disrupting Disparities in Pennsylvania: Retooling for Geographic, Racial and Ethnic Growth" shows that health inequities are most acute among those living in rural and low resourced areas of the state, and among underrepresented populations (particularly Black/African American and Latino), who lack access to health care, experience digital divide and face persistent ...

In an effort to save her beloved animals, Kathy Janson, a Maine Coon cat enthusiast reached out to a University of Cincinnati researcher to find a way to help her pets who were developing heart troubles. Maine Coon cats are known as great mousers, popular farm cats and, of course, for their enormous size. The New England breed is a really big cat and can weigh up to 19 pounds and grow up to 40 inches in length. Janson fell in love with these animals more than 25 years ago bringing them into her Cincinnati suburban home to become part of her family. "Maine ...

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days. The device, known as the mini-MScope, offers an important new tool for studying how neural activity from multiple regions of the outer part of the brain, called the cortex, contribute to behavior, cognition and perception. The groundbreaking study provides new insight into fundamental research that could improve human brain conditions such as concussions, autism, Alzheimer's, and Parkinson's disease, as well as better understanding ...

A study at the University of Chicago Medicine found U.S. women experienced increased incidence of health-related socioeconomic risks (HRSRs), such as food insecurity and interpersonal violence, early in the COVID-19 pandemic. This was associated with "alarmingly high rates" of mental health problems, including depression and anxiety. The research was published April 5 in the Journal of Women's Health. Other studies have found evidence for higher rates of anxiety and depression and related issues, such as alcohol overuse, connected to the pandemic -- but this study is the first to link early pandemic-related changes in HRSRs to mental health effects ...