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Are we genetically 'grounded'?

Are we genetically 'grounded'?
2021-06-11
For centuries, scientists, aeronautic designers and adventure-seekers have sought to replicate the qualities that allow birds to fly, namely wing-structure and balance. However, without an external mechanism such as a hot air balloon or airplane, humans have remained earth-bound, unable to use their own bodies to propel themselves into the stratosphere. While researchers have long-focused on structural factors, like wings, that define the category of bird, a recent study published Science Advances by Professor Avihu Klar at the Hebrew University of Jerusalem's Faculty of Medicine and Prof. Claudio Mello from Oregon Health and Science University found that there are specific molecular characteristics that distinguish birds from animals, and these differences allow birds to flap their ...

Big data: IPK researchers double accuracy in predicting wheat yields

Big data: IPK researchers double accuracy in predicting wheat yields
2021-06-11
The enormous potential of Big Data has already been demonstrated in areas such as financial services and telecommunications. An international team of researchers led by the IPK Leibniz Institute has now tapped the potential of big data for the first time on a large scale for plant research. To this end, data from three projects were used to increase the predictive accuracy for yield in hybrid varieties of wheat. "We were able to draw on the largest dataset published to date, which contains information from almost a decade of wheat research and development," says Prof. Dr. Jochen Reif, Head of the Breeding Research Department at IPK. ...

Examining Diversity of Editors at Leading Medical, Scientific Journals

2021-06-11
What The Study Did: Editorial team composition by gender, race, ethnicity and sexual orientation was assessed at 25 leading medical and scientific journals in this survey study. Authors: James W. Salazar, M.D., M.A.S., of the University of California San Francisco, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2021.2363) Editor's Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, ...

International medical graduate physician deaths from COVID-19 in US

2021-06-11
What The Study Did: International medical graduates often practice as physicians in locations and specialties less preferred by U.S. medical graduates. This study reports on physician mortality from COVID-19, and on the mortality of international medical graduates in particular. Authors: Abraham Verghese, M.D., of Stanford University in California, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.13418) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, ...

International analysis of electronic health records of children, youth hospitalized with COVID-19 in 6 countries

2021-06-11
What The Study Did: Researchers describe international hospitalization trends and key epidemiological and clinical features of children and youth with COVID-19. Authors: Paul Avillach, M.D., Ph.D., of Harvard Medical School in Boston, and Florence Bourgeois, M.D., M.P.H., of Boston Children's Hospital, are the corresponding authors. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.12596) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including ...

Study finds brain areas involved in seeking information about bad possibilities

Study finds brain areas involved in seeking information about bad possibilities
2021-06-11
The term "doomscrolling" describes the act of endlessly scrolling through bad news on social media and reading every worrisome tidbit that pops up, a habit that unfortunately seems to have become common during the COVID-19 pandemic. The biology of our brains may play a role in that. Researchers at Washington University School of Medicine in St. Louis have identified specific areas and cells in the brain that become active when an individual is faced with the choice to learn or hide from information about an unwanted aversive event the individual ...

Anticoagulation in patients hospitalized with COVID-19

2021-06-11
What The Study Did: This study of patients hospitalized with COVID-19 examines the association of anticoagulation treatment with mortality rates. Authors: Valerie M. Vaughn, M.D., M.Sc., of the University of Utah in Salt Lake City, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.11788) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full ...

Comparing symptoms, RNA levels in patients with SARS-CoV-2 infection

2021-06-11
What The Study Did: Researchers compared the association between symptoms and SARS-CoV-2 RNA levels in children and adults. Authors: Erin Chung, M.D., of the University of Washington School of Medicine in Seattle, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2021.2025) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, ...

An omega-3 that's poison for tumors

2021-06-11
So-called "good fatty acids" are essential for human health and much sought after by those who try to eat healthily. Among the Omega-3 fatty acids, DHA or docosahexaenoic acid is crucial to brain function, vision and the regulation of inflammatory phenomena. In addition to these virtues, DHA is also associated with a reduction in the incidence of cancer. How it works is the subject of a major discovery by a multidisciplinary team of University of Louvain (UCLouvain) researchers, who have just elucidated the biochemical mechanism that allows DHA and other related fatty acids to slow the development of tumours. This is a major advance that has recently been published ...

Association of Medicare Advantage star ratings with disparities in quality of care

2021-06-11
What The Study Did: Researchers examined the associations between Medicare Advantage star ratings, which are created using data from all enrollees in a plan, and disparities in care for racial/ethnic minorities and enrollees with lower income and less education. Authors: David J. Meyers, Ph.D., M.P.H., of the Brown University School of Public Health in Providence, Rhode Island, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2021.0793) Editor's Note: The article includes conflict of interest ...

Factors Associated With Self-reported Symptoms of Depression Among Adults With/Without Previous COVID-19

2021-06-11
What The Study Did: This survey study compared features of major depression in people with or without prior COVID-19 illness. Authors: Roy H. Perlis, M.D., M.Sc., of Massachusetts General Hospital in Boston, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.16612) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full study is linked to this news release. Embed this link to provide ...

Promising ovarian cancer treatment proves effective and efficient

Promising ovarian cancer treatment proves effective and efficient
2021-06-11
Reston, VA (Embargoed until 11:00 a.m. EDT, Friday, June 11, 2021)--Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced successful results, dramatically limiting tumor growth and decreasing tumor mass. Designed specifically for ovarian cancers that are resistant to traditional therapies, the new radiopharmaceutical can be produced in 25 minutes at low cost, which leads to better efficiency compared with alternative methods. This research was presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting. According to the American Cancer Society, more than 20,000 women are diagnosed with ovarian cancer each year and nearly 14,000 ...

Autopsy Study of Patients With/Without COVID-19

2021-06-11
What The Study Did: This autopsy study examines differences in skeletal muscle and myocardial inflammation in patients who died with COVID-19 versus other diseases. Authors: Tom Aschman, M.D., and Werner Stenzel, M.D., of the Charite-Universitatsmedizin Berlin, are the corresponding authors. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2021.2004) Editor's Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including ...

Effects of 'Fenton-like' reactions of ferric oxalate on atmospheric oxidation processes and radiative forcing

Effects of 'Fenton-like' reactions of ferric oxalate on atmospheric oxidation processes and radiative forcing
2021-06-11
The Fenton reaction is a chemical transition involving hydrogen peroxide (H2O2) and the ferrous (iron) ion, which acts as a catalyst. This process is used to destroy hazardous contaminants in wastewater through oxidation. In the atmosphere, a similar reaction, or "Fenton-like" reaction, occurs continuously with ferric oxalate([Fe(III)(C2O4)3]3-) and aerosols suspended in the air. This is the most frequent chemical reaction that occurs in the atmosphere. A particle's ability to oxidize is directly related to its phase, either gaseous or aqueous, which has an important impact on secondary organic aerosol (SOA) formation. Therefore, research is necessary not only to evaluate the contribution of this ...

AI predicts how patients with viral infections, including COVID-19, will fare

AI predicts how patients with viral infections, including COVID-19, will fare
2021-06-11
Researchers at University of California San Diego School of Medicine used an artificial intelligence (AI) algorithm to sift through terabytes of gene expression data -- which genes are "on" or "off" during infection -- to look for shared patterns in patients with past pandemic viral infections, including SARS, MERS and swine flu. Two telltale signatures emerged from the study, published June 11, 2021 in eBiomedicine. One, a set of 166 genes, reveals how the human immune system responds to viral infections. A second set of 20 signature genes predicts the severity of a patient's disease. For example, the need to hospitalize or use ...

Star's death will play a mean pinball with rhythmic planets

Star's death will play a mean pinball with rhythmic planets
2021-06-11
Astronomers from University of Warwick and University of Exeter modelling the future of unusual planetary system found a solar system of planets that will 'pinball' off one another Today, the system consists of four massive planets locked in a perfect rhythm Study shows that this perfect rhythm is likely to hold for 3 billion years - but the death of its sun will cause a chain reaction and set the interplanetary pinball game in motion Four planets locked in a perfect rhythm around a nearby star are destined to be pinballed around their solar system when their sun eventually dies, according to a study led by the University of Warwick that peers into its future. Astronomers have modelled how the change in gravitational forces in the system as a result ...

Scientists call for improved management of a weedy tree to protect owl habitat

2021-06-11
When is a weed not a weed? Can native plants be weeds? Sweet pittosporum (Pittosporum undulatum) was once a well-behaved tree growing in gullies from Gippsland in Victoria up to Brisbane in Queensland. But it is now a major problem, leading to an almost complete suppression of native vegetation where it has invaded. Programs to clear it have successfully allowed indigenous plants to return, and within 15 years, with moderate follow up, treated sites are well on the way to successful restoration. However, there has been some debate on whether this is good or bad for birds such as the threatened Powerful Owl. New research by Monash University scientists from the School of Biological Sciences published today in Ecological Solutions and ...

Astronomers spot a 'blinking giant' near the centre of the Galaxy

Astronomers spot a 'blinking giant' near the centre of the Galaxy
2021-06-11
Astronomers have spotted a giant 'blinking' star towards the centre of the Milky Way, more than 25,000 light years away. An international team of astronomers observed the star, VVV-WIT-08, decreasing in brightness by a factor of 30, so that it nearly disappeared from the sky. While many stars change in brightness because they pulsate or are eclipsed by another star in a binary system, it's exceptionally rare for a star to become fainter over a period of several months and then brighten again. The researchers believe that VVV-WIT-08 may belong to a new class of 'blinking giant' binary star system, where a giant star ? 100 times larger ...

Oncotarget: Prostate cancer and a possible link with schizophrenia

2021-06-11
Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively. The following gene polymorphisms known to be associated with neuropsychiatric disorders were investigated: A. The STin2 VNTR in the serotonin transporter SLC6A4 gene; B. The 30-bp VNTR in the monoamine oxidase A MAOA gene; C. The Val158Met polymorphism in the catechol-ortho-methyltransferase ...

Novel fast-beam-switching transceiver takes 5G to the next level

Novel fast-beam-switching transceiver takes 5G to the next level
2021-06-11
Scientists at Tokyo Institute of Technology (Tokyo Tech) and NEC Corporation jointly develop a 28-GHz phased-array transceiver that supports efficient and reliable 5G communications. The proposed transceiver outperforms previous designs in various regards by adapting fast beam switching and leakage cancellation mechanism. With the recent emergence of innovative technologies, such as the Internet of Things, smart cities, autonomous vehicles, and smart mobility, our world is on the brink of a new age. This stimulates the use of millimeter-wave bands, which have far more signal bandwidth, to accommodate these new ideas. 5G can offer data ...

Study sheds light on treatment options for devastating childhood brain cancer

Study sheds light on treatment options for devastating childhood brain cancer
2021-06-10
Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine. Radiation therapy to the whole brain and spine followed by an extra radiation dose to the back of the brain prevents this spread and has been the standard of care. However, the radiation used to treat such tumors takes a toll on the brain, damaging cognitive function, especially in younger patients whose brains are just beginning to develop. A national study led by Washington University School of Medicine in St. Louis and St. Jude Children's Research Hospital suggests that children with what is called "average risk medulloblastoma" can receive a radiation "boost" to a smaller ...

Common diabetes drug shows promise as treatment for COVID-19 lung inflammation

Common diabetes drug shows promise as treatment for COVID-19 lung inflammation
2021-06-10
Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans. Metformin works by lowering glucose production in the liver, reducing blood sugar levels that, in turn, improve the body's response to insulin. But scientists have also noted that metformin possesses anti-inflammatory properties, though the basis for this activity was not known. In a study published online June 8, 2021 in the journal END ...

'Disagreeable' married men who shirk domestic responsibilities earn more at work

2021-06-10
Married men who don't help out around the house tend to bring home bigger paychecks than husbands who play a bigger role on the domestic chores front. New research from the University of Notre Dame shows that "disagreeable" men in opposite-sex marriages are less helpful with domestic work, allowing them to devote greater resources to their jobs, which results in higher pay. In contemporary psychology, "agreeableness" is one of the "Big Five" dimensions used to describe human personality. It generally refers to someone who is warm, sympathetic, kind and cooperative. Disagreeable people do not tend to exhibit these characteristics, and they tend to ...

Ocean microplastics: First global view shows seasonal changes and sources

2021-06-10
An estimated 8 million tons of plastic trash enters the ocean each year, and most of it is battered by sun and waves into microplastics--tiny flecks that can ride currents hundreds or thousands of miles from their point of entry. The debris can harm sea life and marine ecosystems, and it's extremely difficult to track and clean up. Now, University of Michigan researchers have developed a new way to spot ocean microplastics across the globe and track them over time, providing a day-by-day timeline of where they enter the water, how they move and where they tend to collect. The approach relies on ...

Study shows how rudeness leads to anchoring, including in medical diagnoses

2021-06-10
Have you ever been cut off in traffic by another driver, leaving you still seething miles later? Or been interrupted by a colleague in a meeting, and found yourself replaying the event in your head even after you've left work for the day? Minor rude events like this happen frequently, and you may be surprised by the magnitude of the effects they have on our decision-making and functioning. In fact, recent research co-authored by management professor Trevor Foulk at the University of Maryland's Robert H. Smith School of Business suggests that in certain situations, incidental rudeness like this can be deadly. In "Trapped ...
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