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Moffitt researchers develop first genetic test to predict tumor sensitivity to radiation therapy

2015-07-23
TAMPA, Fla. - Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy. Moffitt Cancer Center researchers have contributed to these advances by developing the first test that analyzes the sensitivity of tumors to radiation therapy. They discovered that colon cancer metastases have varying sensitivity to radiation therapy based on their anatomic location. Researchers from Moffitt previously developed ...

Novel algorithm identifies DNA copy-number landscapes in African American colon cancers

2015-07-23
An algorithm dubbed ENVE could be the Google for genetic aberrations -- and it comes from Case Western Reserve. Remember the World Wide Web before the famed search engine? The web offered extraordinary amounts of information, but no consistently reliable way to secure relevant results. Cancer researchers at Case Western Reserve encountered a comparable conundrum when considering reams of data about the body that new technological advances provide -- how could they tell what parts of the information actually offer value. In this instance, the goal was to distinguish ...

Spintronics: Molecules stabilizing magnetism

Spintronics: Molecules stabilizing magnetism
2015-07-23
This news release is available in German. Organic molecules allow producing printable electronics and solar cells with extraordinary properties. In spintronics, too, molecules open up the unexpected possibility of controlling the magnetism of materials and, thus, the spin of the flowing electrons. According to what is reported in Nature Materials by a German-French team of researchers, a thin layer of organic molecules can stabilize the magnetic orientation of a cobalt surface. (DOI: 10.1038/NMAT4361) "This special interaction between organic molecules and metal ...

Reintroduced Channel Islands eagles thrive on a diet of seabirds and fish

Reintroduced Channel Islands eagles thrive on a diet of seabirds and fish
2015-07-23
Reintroducing a species into an area where it has vanished can be a great tool for conservation, but for reintroduction to be successful it's crucial to understand how the habitat has changed in the interim and whether the reintroduced species will be able to thrive in its former home. Extirpated in the 1960s as a result of human activity, Bald Eagles (Haleiaeetus leucocephalus) have been reintroduced to California's Channel Islands over the last 35 years. A study published this week in The Condor: Ornithological Applications examined the diets of these reestablished eagles ...

Social climbing makes the English happier than Americans

2015-07-23
People who grew up in a working class family are more satisfied in later life than those from a higher class background according to new research from The University of Manchester. The study by Dr Bram Vanhoutte and Professor James Nazroo, published in the Journal of Population Ageing, also found that English people who climb the social ladder are more content and happy when they get older than people in the States who are similarly upwardly mobile. The research sought to find out whether social mobility makes people happier in later life while taking into account ...

Investigators developed a tool for more accurate interpretation of biomedical research

2015-07-23
Investigators affiliated with VIB and UGent recently achieved great success with a study involving biomedical research on mouse models. The research group of Prof Peter Vandenabeele (VIB/UGent) recently used tangible examples to demonstrate how the side effects of genetic modification of mice can complicate the interpretation of biomedical research. The team developed a web tool that allows scientists to estimate the impact of this phenomenon more accurately. Their findings were recently published in the medical journal Immunity and received ample attention by a preview ...

Mangroves help protect against sea level rise

2015-07-23
Mangrove forests could play a crucial role in protecting coastal areas from sea level rise caused by climate change, according to new research involving the University of Southampton. A joint study between researchers at the University of Southampton along with colleagues from the Universities of Auckland and Waikato in New Zealand used leading-edge mathematical simulations to study how mangrove forests respond to elevated sea levels. Taking New Zealand mangrove data as the basis of a new modelling system, the team were able to predict what will happen to different types ...

Study: Implicit bias against lesbians, gays decreasing across demographic groups

2015-07-23
The U.S. Supreme Court's recent ruling legalizing marriage between same-sex couples in all 50 states follows on the heels of national polls showing rapid cultural changes in attitudes toward lesbian and gay people. A new University of Virginia study confirms this, showing that not only are Americans' conscious and unconscious biases against lesbian women and gay men decreasing across all demographic groups, but the trend also appears to be accelerating. "Many people have this gut feeling that our culture has changed," said lead researcher Erin Westgate, a doctoral psychology ...

Leading experts prescribe how to make cancer drugs more affordable

2015-07-23
ROCHESTER, MINN. - A group of 118 of the nation's leading cancer experts have drafted a prescription for reducing the high cost of cancer drugs and voiced support for a patient-based grassroots movement demanding action on the issue. Their recommendations and support are outlined in a commentary, co-authored by the group, in the journal Mayo Clinic Proceedings. "High cancer drug prices are affecting the care of patients with cancer and our health care system," says lead author Ayalew Tefferi, M.D., a hematologist at Mayo Clinic. "The average gross household income in ...

Research suggests retail meat is a potential vehicle for disease-causing Klebsiella

2015-07-23
WASHINGTON, DC (July 23, 2015) -- Chicken, turkey and pork sold in grocery stores harbors disease-causing bacteria known as Klebsiella pneumoniae, according to a new study. The research, which was published online today in the journal Clinical Infectious Diseases, shows that contaminated meat may be an important source of human exposure to Klebsiella.The U.S. food safety system has traditionally focused on a few well-known bacteria like Listeria, Salmonella and Campylobacter, which cause millions of cases of food poisoning every year. The research published today suggests ...

Researchers identify plant cultivation in a 23,000-year-old site in the Galilee

2015-07-22
The Middle East is called the "Cradle of Civilization" because it is where our hunter-gatherer ancestors first established sedentary farming communities. Recently, the traditional dating of humans' first agricultural attempt was shaken up by the discovery of the earliest-known example of plant cultivation in the Levant, 11,000 years earlier than previously accepted. The team of archaeologists, botanists, and ecologists from Bar-Ilan University, Haifa University, Tel Aviv University, and Harvard University published their work in the scientific journal Plos One on July ...

Tel Aviv University among researchers to discover first evidence of farming in Mideast

2015-07-22
Until now, researchers believed farming was "invented" some 12,000 years ago in the Cradle of Civilization -- Iraq, the Levant, parts of Turkey and Iran -- an area that was home to some of the earliest known human civilizations. A new discovery by an international collaboration of researchers from Tel Aviv University, Harvard University, Bar-Ilan University, and the University of Haifa offers the first evidence that trial plant cultivation began far earlier -- some 23,000 years ago. The study focuses on the discovery of the first weed species at the site of a sedentary ...

Coping by avoidance in making decisions for relatives in ICU may lead to PTSD

2015-07-22
Family members who make major medical decisions for relatives in an intensive care unit (ICU) may suffer posttraumatic stress disorder (PTSD) if they cope by avoiding the situation, according to a new study by scientists at Case Western Reserve University's Frances Payne Bolton School of Nursing. The patient isn't the only one affected by the long stay, according to Amy Petrinec, from the school of nursing. Family members may suffer, especially if they're required to make medical decisions with long-range consequences they may not understand, or are reluctant to question. Family ...

Teeth reveal lifetime exposures to metals, toxins

2015-07-22
(NEW YORK CITY - July 22, 2015) Is it possible that too much iron in infant formula may potentially increase risk for neurodegenerative diseases like Parkinson's in adulthood -- and are teeth the window into the past that can help us tell? This and related theories were described in a "Perspectives" article authored by researchers from the Icahn School of Medicine at Mount Sinai and the University of Technology Sydney and Florey Institute of Neuroscience and Mental Health in Australia, and published online recently in Nature Reviews Neurology. "Teeth are of particular ...

Using low-dose irradiation, researchers can now edit human genes

2015-07-22
LOS ANGELES (July 22, 2015) - For the first time, researchers have employed a gene-editing technique involving low-dose irradiation to repair patient cells, according to a study published in the journal Stem Cells Translational Medicine. This method, developed by researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, is 10 times more effective than techniques currently in use. "This novel technique allows for far more efficient gene editing of stem cells and will increase the speed of new discoveries in the field," said co-senior author Clive ...

Climate change reduces coral reefs' ability to protect coasts

2015-07-22
WASHINGTON, D.C. - Coral reefs, under pressure from climate change and direct human activity, may have a reduced ability to protect tropical islands against wave attack, erosion and salinization of drinking water resources, which help to sustain life on those islands. A new paper gives guidance to coastal managers to assess how climate change will affect a coral reef's ability to mitigate coastal hazards. About 30 million people are dependent on the protection by coral reefs as they live on low-lying coral islands and atolls. At present, some of these islands experience ...

Schools with higher black, minority populations call cops, not docs

2015-07-22
Poor schools that have more black and minority students tend to punish students rather than seek medical or psychological interventions for them, according to a Penn State sociologist. "There's been a real push toward school safety and there's been a real push for schools to show they are being accountable," said David Ramey, assistant professor of sociology and criminology. "But, any zero-tolerance policy or mandatory top-down solutions might be undermining what would be otherwise good efforts at discipline, and not establishing an environment based around all the options ...

New smart drug targets and reduces site-specific inflammation

2015-07-22
BEER-SHEVA, Israel...July 22, 2015 - Ben-Gurion University of the Negev (BGU) and University of Colorado researchers have developed a dynamic "smart" drug that targets inflammation in a site-specific manner and could enhance the body's natural ability to fight infection and reduce side effects. The uniqueness of this novel anti-inflammatory molecule, reported in the current issue of Journal of Immunology, can be found in a singular property. When injected, it is as a non-active drug. However, a localized site with excessive inflammation will activate it. Most other anti-inflammatory ...

Computer security tools for journalists lacking in a post-Snowden world

2015-07-22
Edward Snowden's leak of classified documents to journalists around the world about massive government surveillance programs and threats to personal privacy ultimately resulted in a Pulitzer Prize for public service. Though Snowden had no intention of hiding his identity, the disclosures also raised new questions about how effectively news organizations can protect anonymous sources and sensitive information in an era of constant data collection and tracking. A new study by University of Washington and Columbia University researchers that will be presented next month ...

New study indicates ankle-brachial index associated with mild cognitive impairment

2015-07-22
Amsterdam, The Netherlands, July 22, 2015 - In a large population-based study of randomly selected participants in Germany, researchers found that mild cognitive impairment (MCI) occurred significantly more often in individuals diagnosed with a lower ankle brachial index (ABI), which is a marker of generalized atherosclerosis and thus cumulative exposure to cardiovascular risk factors during lifetime. Interestingly, this strong association was only observed in patients with non-amnestic MCI, but not amnestic MCI. There also was no independent association of MCI and intima ...

NASA's RapidScat identifies Typhoon Halola's strongest side

NASAs RapidScat identifies Typhoon Halolas strongest side
2015-07-22
Typhoon Halola's strongest typhoon-force winds were located on the northern half of the storm, as identified from the RapidScat instrument that flies aboard the International Space Station. RapidScat gathered surface wind data on the Typhoon Halola on July 21at 2 p.m. GMT (10 a.m. EDT). RapidScat data showed that the strongest sustained winds stretched from northwest to northeast of the center at speeds up to 30 meters per second (108 kph/67 mph). Strong winds wrapped around the center of circulation from northwest to east to the southern quadrant, while the weakest winds ...

Twisted wasps: Two new unique parasitoid wasp species sting the heart of Europe

Twisted wasps: Two new unique parasitoid wasp species sting the heart of Europe
2015-07-22
Much to his own surprise, Hannes Baur from the Natural History Museum Bern not only reports on whole two new parasitoid wasps at the heart of Europe, the Swiss Alps and Swiss Central Plateau. While the common discovery usually involves cryptic, or "camouflaging" within their groups species, his stand out. Baur's work is published in the open-access journal ZooKeys. The insects he describes are visibly quite unique with their body structures. In the case of the Pteromalus briani wasp, its extraordinarily protruding hind legs differentiate it among the whole family. Meanwhile, ...

Mowing dry detention basins makes mosquito problems worse, team finds

Mowing dry detention basins makes mosquito problems worse, team finds
2015-07-22
CHAMPAIGN, Ill. -- A study of the West Nile virus risk associated with "dry" water-detention basins in Central Illinois took an unexpected turn when land managers started mowing the basins. The mowing of wetland plants in basins that failed to drain properly led to a boom in populations of Culex pipiens mosquitoes, which can carry and transmit the deadly virus, researchers report. A paper describing their findings is in press in the journal Ecological Applications. The team, led by University of Illinois postdoctoral researcher Andrew Mackay, found that mowing down cattails ...

This week from AGU: Arctic mercury, EarthQuiz challenge & 5 new research papers

2015-07-22
GeoSpace Warmer air, less sea ice lead to mercury decline in Arctic Ocean The amount of mercury in the Arctic Ocean is declining as the region rapidly warms and loses sea ice, according to a new study. A new study in Geophysical Research Letters suggests that fish, marine mammals, polar bears, whales and humans in the Arctic might potentially be consuming lower amounts of toxic methylmercury as the region warms. Eos.org Puzzles invite you to explore Earth with interactive imagery The EarthQuiz challenge can take you to virtual field locations with just the click of ...

Predicting the shape of river deltas

2015-07-22
The Mississippi River delta is a rich ecosystem of barrier islands, estuaries, and wetlands that's home to a diverse mix of wildlife -- as well as more than 2 million people. Over the past few decades, the shape of the delta has changed significantly, as ocean waves have carved away at the coastline, submerging and shrinking habitats. To keep flooding at bay, engineers have erected dams and levees along the river. However, it's unclear how such protective measures will affect the shape of the river delta, and its communities, over time. Now researchers from MIT and ...
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