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Early intervention could boost education levels

2014-10-22
Taking steps from an early age to improve childhood education skills could raise overall population levels of academic achievement by as much as 5%, and reduce socioeconomic inequality in education by 15%, according to international research led by the University of Adelaide. In a study now published in the journal Child Development, researchers from the University of Adelaide's School of Population Health and colleagues at the University of Bristol in the UK have modelled the likely outcomes of interventions to improve academic skills in children up to school age. They ...

Steadily rising increases in mitochondrial DNA mutations cause abrupt shifts in disease

Steadily rising increases in mitochondrial DNA mutations cause abrupt shifts in disease
2014-10-22
Philadelphia, Oct. 22, 2014 – New work by a pioneering scientist details how subtle changes in mitochondrial function may cause a broad range of common metabolic and degenerative diseases. Mitochondria are tiny energy-producing structures within our cells that contain their own DNA. The new research shows that small changes in the ratio of mutant to normal mitochondrial DNA within the thousands of mitochondrial DNAs inside each cell can cause abrupt changes in the expression of numerous genes within the nuclear DNA. Furthermore, the different proportions of mutant ...

The unexpected benefits of adjustable rate mortgages

2014-10-22
Using loan level data matched to consumer credit records, researchers have been able to determine that a reduction in mortgage payments of as little as $150 a month spurred a reduction in mortgage defaults and an increase in consumer spending (particularly the financing of automobile purchases), while improving household credit ratings. University of Chicago Booth School of Business Professor Amit Seru, together with Benjamin J. Key of UChicago's Harris School of Public Policy, Tomasz Piskorski of the Columbia Business School and Vincent Yao of Fannie Mae authored "Mortgage ...

Expert recommendations for diagnosing pediatric acute onset neuropsychiatric syndrome

Expert recommendations for diagnosing pediatric acute onset neuropsychiatric syndrome
2014-10-22
New Rochelle, NY, October 22, 2014—A panel of leading clinicians and researchers across various general and specialty pediatric fields developed a consensus statement recommending how to evaluate youngsters in whom neuropsychiatric symptoms suddenly develop, including the abrupt, dramatic onset of obsessive-compulsive disorder (OCD). This difficult diagnosis is typically made by pediatricians or other primary care clinicians and child psychiatrists, who will benefit from the guidance provided in the recommendations published in Journal of Child and Adolescent Psychopharmacology, ...

Researchers resolve the Karakoram glacier anomaly, a cold case of climate science

Researchers resolve the Karakoram glacier anomaly, a cold case of climate science
2014-10-22
Researchers from Princeton University and other institutions may have hit upon an answer to a climate-change puzzle that has eluded scientists for years, and that could help understand the future availability of water for hundreds of millions of people. In a phenomenon known as the "Karakoram anomaly," glaciers in the Karakoram mountains, a range within the Himalayas, have remained stable and even increased in mass while many glaciers nearby — and worldwide — have receded during the past 150 years, particularly in recent decades. Himalayan glaciers provide ...

Global consumption an increasingly significant driver of tropical deforestation

Global consumption an increasingly significant driver of tropical deforestation
2014-10-22
International trade with agricultural and wood products is an increasingly important driver of tropical deforestation. More than a third of recent deforestation can be tied to production of beef, soy, palm oil and timber. "The trend is clear, the drivers of deforestation have been globalized and commercialized", says assistant professor Martin Persson, Chalmers University of Technology. In a report commissioned by US think-tank Center for Global Development (CGD) Martin Persson and colleagues in Linköping, Sweden, and Vienna, Austria, have investigated to which extent ...

An effective, cost-saving way to detect natural gas pipeline leaks

2014-10-22
Major leaks from oil and gas pipelines have led to home evacuations, explosions, millions of dollars in lawsuit payouts and valuable natural resources escaping into the air, ground and water. But in a report in ACS' journal Industrial & Engineering Chemistry Research, scientists say they have developed a new software-based method that finds leaks even when they're small, which could help prevent serious incidents — and save money for customers and industry. Gary Valtinson and Miguel Bagajewicz note that using pipelines to move oil, gas and even water from one place ...

Susceptibility for relapsing major depressive disorder can be calculated

2014-10-22
Selver Demic and his colleagues from the Mercator Research Group have set out to find out more about the causes of depression. "Approx. 20 per cent of the population will suffer a de-pressive episode in the course of their lives," says Demic. "This cohort of 20 per cent includes people who will never again experience any problems after that one-time episode is over. The others, however, will suffer repeatedly or chronically under the disorder, despite taking appropriate medication. We want to use our model to explain the occurrence and recurrence rates." Unfortunate ...

Indiana Project screenings show need for more mental health services in youth detention

2014-10-22
INDIANAPOLIS -- Indiana is at the forefront of providing mental health screening and services to juvenile offenders, but more efforts are needed to improve the services provided to detained youths, according to Indiana University School of Medicine research findings published in the October issue of the American Journal of Public Health. "A Statewide Collaboration to Initiate Mental Health Screening and Assess Services for Indiana Detained Youths" reviewed 25,265 detention visits of 15,461 youths occurring in 2008 to 2011. The youths were incarcerated in 16 detention ...

Cooling with molecules

Cooling with molecules
2014-10-22
This news release is available in German. An international team of scientists have become the first ever researchers to successfully reach temperatures below minus 272.15 degrees Celsius – only just above absolute zero – using magnetic molecules. The physicists and chemists are presenting their new investigation today (22 October 2014) in the scientific journal Nature Communications. It was developed by six scientists from Bielefeld University, the University of Manchester (Great Britain), and the Universidad de Zaragoza (Spain). Scientists usually express ...

Harvard study offers first-ever look at how NCAA concussion guidelines are followed

2014-10-22
Though most NCAA colleges and universities have created programs to help athletes deal with concussions, a new Harvard study has found that, when it comes to specific components of those plans, many institutions still lag behind accepted standards. The study, the first-ever comprehensive examination of how colleges and universities have complied with the Concussion Policy and Legislation adopted by the NCAA in 2010, is based on the results of a survey sent to all 1,066 NCAA member institutions. Of those institutions, 907 schools responded. The results, according to ...

Silencing the speech gene FOXP2 causes breast cancer cells to metastasize

2014-10-22
BOSTON – It is an intricate network of activity that enables breast cancer cells to move from the primary breast tumor and set up new growths in other parts of the body, a process known as metastasis. Now a research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has identified an unexpected link between a transcription factor known to regulate speech and language development and metastatic colonization of breast cancer. Currently described online in Cell Stem Cell, the new findings demonstrate that, when silenced, the FOXP2 transcription ...

Study finds no increase in pregnancy-related death for African-American women

2014-10-22
October 22, 2014 – In contrast to national trends, a study performed at Alabama's largest hospital finds no racial difference in the risk of pregnancy-related death between African American and Caucasian women, reports the November issue of Anesthesia & Analgesia. However, the results show a significant increase in maternal mortality for women who live greater distances from the hospital, according to the study Dr Michael Froelich of University of Alabama at Birmingham (UAB) and colleagues. The findings point to differences in health care access as a possible explanation ...

Clinical trial could change standard treatment for stroke

2014-10-22
A large international clinical trial has shed new light on the effectiveness of current hospital protocols for managing blood pressure in stroke patients. The two-part ENOS trial (Efficacy of Nitric Oxide in Stroke,) was carried out at The University of Nottingham in collaboration with 23 countries to try to solve two major conundrums faced by doctors when treating people who have suffered a stroke — should blood pressure be lowered using medicated skin patches, and should existing blood pressure medication be stopped or continued after a stroke? The results of ...

Association between air toxics and childhood autism

2014-10-22
PITTSBURGH, Oct. 22, 2014 – Children with autism spectrum disorder (ASD) were more likely to have been exposed to higher levels of certain air toxics during their mothers' pregnancies and the first two years of life compared to children without the condition, according to the preliminary findings of a University of Pittsburgh Graduate School of Public Health investigation of children in southwestern Pennsylvania. This research, funded by The Heinz Endowments, will be presented today at the American Association for Aerosol Research annual meeting in Orlando, Fla. ...

Aphthous ulcers: Causes of mucosal inflammation are unclear

2014-10-22
A painful inflamed lesion on the oral mucosa, which often seems to be burning at the periphery: every third individual has at one point had such a lesion—an aphthous ulcer. Often they resolve after a brief period of time. In 2% to 10% of patients these lesions are recurrent and require medical treatment. Unfortunately, as Andreas Altenberg and co-authors point out in a current review on the therapy of aphthous ulcers (Dtsch Arztebl Int 2014; 111: 665–73), the etiology of these lesions is unclear. Thus aphthous ulcers can only be treated symptomatically. Even ...

Sopping up proteins with thermosponges

2014-10-22
Boston, MA – A research team led by Brigham and Women's Hospital (BWH) has developed and tested a novel nanoparticle platform that efficiently delivers clinically important proteins in vivo in initial proof-of-concept tests. Nanoparticles, which are particles measuring nanometers in size, hold promise for a range of applications, including human therapeutics. The key advantage of the new platform, known as a thermosponge nanoparticle, is that it eliminates the need for harsh solvents, which can damage the very molecules the particles are designed to carry. The study ...

BJOG releases MPT special supplement

2014-10-22
(Sacramento, CA): Broad-spectrum prevention that can simultaneously prevent unintended pregnancy along with STIs, including HIV, is on the horizon say experts in a special supplement of the BJOG: An International Journal of Obstetrics and Gynaecology. The issue features an international assemblage of researchers, funders, developers and advocates who identify the pressing global health rationale for MPTs and present new research and strategies for making the go/no-go funding and research decisions that shape the field. The invited guest editor for the supplement is Dr. ...

The 2011 English summer riots: Courts accused of 'collective hysteria'

2014-10-22
A review of sentencing following the 2011 English riots has shown that sentences were much harsher than realised at first. And just as people got caught up in the riots and acted out of character the study, carried out by The University of Manchester and Liverpool John Moores University, found that the courts themselves got caught up in a similar kind of collective hysteria. Dr Hannah Quirk, a Senior Lecturer in Criminal Law and Justice from The University of Manchester, was the co-author of the research which has just been published in The British Journal of Criminology. ...

Protecting us from our cells

Protecting us from our cells
2014-10-22
Our immune system defends us from harmful bacteria and viruses, but, if left unchecked, the cells that destroy those invaders can turn on the body itself, causing auto-immune diseases like type-1 diabetes or multiple sclerosis. A molecule called insulin-like growth factor-1 (IGF-1) boosts the body's natural defence against this 'friendly fire', scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have found. The findings, published today in EMBO Molecular Medicine, are especially exciting because IGF-1 is already approved for use in patients, ...

New window on the early universe

New window on the early universe
2014-10-22
Using two world-class supercomputers, the researchers were able to demonstrate the effectiveness of their approach by simulating the formation of a massive galaxy at the dawn of cosmic time. The ALMA radio telescope – which stands at an elevation of 5,000 meters in the Atacama Desert of Chile, one of the driest places on earth – was then used to forge observations of the galaxy, showing how their method improves upon previous efforts. It is extremely difficult to gather information about galaxies at the edge of the Universe: the signals from these heavenly ...

Proper dental care linked to reduced risk of respiratory infections in ICU patients

2014-10-22
CHICAGO (October 22, 2014) – New research shows vulnerable patients in the Intensive Care Unit (ICU) who received enhanced oral care from a dentist were at significantly less risk for developing a lower respiratory tract infection (LRTI), like ventilator-associated pneumonia, during their stay. The study was published in the November issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA). "Bacteria causing healthcare-associated infections often start in the oral cavity," said Fernando Bellissimo-Rodrigues, ...

Automated tracking increases compliance of flu vaccination for health-care personnel

2014-10-22
CHICAGO (October 22, 2014) – New research found tracking influenza vaccination of healthcare personnel through an automated system increased vaccination compliance and reduced workload burden on human resources and occupational health staff. The study is published in the November issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA). "Mandatory vaccination programs help protect vulnerable patients, but can be tremendously time and resource dependent," said Susan Huang, MD, MPH, an author of ...

Olive oil more stable and healthful than seed oils for frying food

2014-10-22
Frying is one of the world's most popular ways to prepare food — think fried chicken and french fries. Even candy bars and whole turkeys have joined the list. But before dunking your favorite food in a vat of just any old oil, consider using olive. Scientists report in ACS' Journal of Agricultural and Food Chemistry that olive oil withstands the heat of the fryer or pan better than several seed oils to yield more healthful food. Mohamed Bouaziz and colleagues note that different oils have a range of physical, chemical and nutritional properties that can degrade ...

Skin patch could replace the syringe for disease diagnosis

2014-10-22
Drawing blood and testing it is standard practice for many medical diagnostics. As a less painful alternative, scientists are developing skin patches that could one day replace the syringe. In the ACS journal Analytical Chemistry, one team reports they have designed and successfully tested, for the first time, a small skin patch that detected malaria proteins in live mice. It could someday be adapted for use in humans to diagnose other diseases, too. Simon R. Corrie and colleagues note that while blood is rich with molecular clues that tell a story about a person's health, ...
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