Home Office data shows the number of police officers voluntarily resigning from the force in England and Wales has more than doubled in the last eight years. Scant attention has been paid to the reason for this mass exodus. Until now. Researchers from the University of Portsmouth studied government statistics, and discovered the numbers of officers voluntarily resigning from the police service is rising - from 1,158 in the year ending March 2012 to 2,363 in the year ending March 2020. The figure amounts to 1.83 per cent of the total police officer population in England and Wales up from 0.86 per cent eight years ago. Dr Sarah Charman, from the Institute of Criminal Justice Studies at the University of Portsmouth, led the study. ...

New research will enhance corona safety during cruises and help cruise lines to again attract passengers onboard Researchers within Cell Biology and Industrial Management at Åbo Akademi University have developed models aimed at ensuring corona safety during cruises. The coronavirus pandemic stopped the cruise industry more or less completely. Major international cruise lines, such as Royal Caribbean Group and Carnival Corporation, largely suspended their cruises during 2020, which resulted in practically zero turnover and losses amounting to billions. Upon assignment by Business Finland, an interdisciplinary research team has been working to find solutions for managing the current crisis ...

A lot of us recycle our old textiles, but few of us know that they are very difficult to re-use, and often end up in landfills anyway. Now, researchers at Lund University in Sweden have developed a method that converts cotton into sugar, that in turn can be turned into spandex, nylon or ethanol. WATCH: New method transforms old cotton into glucose https://www.youtube.com/watch?v=B1V--prLs08 Every year, an estimated 25 million tonnes of cotton textiles are discarded around the world. In total, 100 million tonnes of textiles are thrown out. In Sweden, most of the material goes straight into an incinerator and becomes district heating. In other places, it is even worse, as clothes usually end up in landfills. "Considering that cotton is a renewable ...

TAMPA, Fla. - Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options. Drugs that target the G12C mutation in KRAS have shown some activity in lung cancer; however, alternative signaling pathways are often activated that bypass the KRAS inhibitor, resulting in drug resistance. In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers show that various subtypes of lung cancer cells activate different signaling pathways in response to KRASG12C inhibitor treatment. These results may help identify potential combination therapy approaches and guide ...

Atmospheric carbon dioxide (CO2) is a major driver of global warming, but this gas could also serve as a valuable resource. Researchers at KAUST have developed an efficient catalyst that uses light energy to convert CO2 and hydrogen into methane (CH4). This counteracts the release of CO2 when methane is burned as a fuel. Many researchers worldwide are exploring ways to convert CO2 into useful carbon-based chemicals, but their efforts have been limited by low efficiencies that restrict the potential for large-scale application. "Our approach is based on the synergistic combination of light and heat, known as the photothermal effect," says postdoc Diego Mateo. He explains that the heat is generated by the interaction of light with the catalyst, ...

Spikes in temperature can affect a plant's fertility, resulting in a reduction of yield and economic loss How plants can protect themselves from stress has been studied by a consortium led by the University of Warwick Two argonaute-like proteins protect the plant's fertility, understanding these proteins is critical to safeguarding crop production As Temperatures rise due to global warming the need to protect plants from stressful conditions has increased, as stress can cause a loss in yield and cause further impact economically. A consortium led by the University of Warwick have successfully identified ...

Respiratory viruses such as SARS-CoV-2 (causing COVID-19) can often catalyse an overactive immune response that leads to a life-threatening cycle, known as a cytokine storm. Analysing cytokine responses from patients infected with SARS-CoV-2 and similar common respiratory viruses has unearthed glaringly important differences in how SARS-CoV-2 affects cytokines compared to other common respiratory viruses. The comprehensive data resource aims to help specialists identify better treatments and diagnosis of underlying causes that can cause the deadly cytokine storm. Scientists at the ...

In order to avoid the occurrence of such effects, the Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV) recommended guidance values for maximum THC levels in various food groups in 2000. The guidance value for beverages was given as 0.005 mg/kg, for edible oils with 5 mg/kg and for all other foods with 0.150 mg/kg. In 2018, the BfR came to the conclusion that these values no longer correspond to current scientific knowledge. Instead, the BfR recommends that the toxicological assessment of hemp-containing foods be carried out on the basis of the acute reference dose (ARfD) of 1 microgram Δ-THC/kg body-weight derived by the European Food Safety Authority (EFSA) in 2015. The ARfD specifies the estimated maximum quantity ...

DNA nanotechnology - the research field using DNA molecules as building material - has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures. DNA nanostructures, such as DNA origami, serve as an excellent foundation for nanocarrier-based drug delivery applications, and examples of their use in medical treatments have already been demonstrated. Although the stability of such DNA nanostructures under physiological conditions can be improved, little is known about their digestion by endonucleases, which, found everywhere in our blood and tissues, are responsible for destroying foreign DNA in our bodies. To tackle this emerging question, a ...

Scientists have taken a significant step forward in their search for the origin of a progressive eye condition which causes sight loss and can lead to corneal transplant. A new study into keratoconus by an international team of researchers, including a University of Leeds group led by Chris Inglehearn, Professor of Molecular Ophthalmology in the School of Medicine, has for the first time detected DNA variations which could provide clues as to how the disease develops. Keratoconus causes the cornea, which is?the clear outer layer?at the front of the eye, to thin and bulge outwards into a cone shape over time, resulting in blurred vision and sometimes blindness. It usually emerges in young adulthood, often with lifelong ...

Researchers are in the search for generalisable rules and patterns in nature. Biogeographer Julia Kemppinen together with her colleagues tested if plant functional traits show similar patterns along microclimatic gradients across far-apart regions from the high-Arctic Svalbard to the sub-Antarctic Marion Island. Kemppinen and her colleagues found surprisingly identical patterns. It is widely known that global vegetation patterns and plant properties follow major differences in climate. Yet, it has remained a mystery how well the same rules can be applied at very local scales. Are responses to the environment similar in plant communities ...

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process. The formation of ribosomal components involves multiple helper proteins which, much like instruments in an orchestra, interact in a coordinated way. One of these helper proteins - protein ObgE - acts as the conductor, guiding the entire process. The research, which produced the first-ever image-based reconstruction of this process, has been published in Molecular Cell*. Ribosomes are an essential component of all living cells. Frequently referred to as 'molecular protein factories', they translate genetic information into chains of linked-up ...

What can you see on this picture (next to thearticle)? Say what comes to your mind immediately! If you said „star", you focus rather on the details, if you said „sun", then rather on the global pattern. People can be different in whether they typically see the forest or the trees, but the dominant attentional mode is focusing first on the whole, and then on the details. This is the same with children. Or so it has been until now! Children of the Alpha Generation (who has been born after 2010) typically grow up with mobile devices in their hands which seems to change how they perceive the world, as Hungarian researchers showed. The Alpha Generation Lab of Diagnostics and Therapy Excellence Programme at Eötvös Loránd University (Budapest) studies ...

Materials - Quantum building blocks Oak Ridge National Laboratory scientists demonstrated that an electron microscope can be used to selectively remove carbon atoms from graphene's atomically thin lattice and stitch transition-metal dopant atoms in their place. This method could open the door to making quantum building blocks that can interact to produce exotic electronic, magnetic and topological properties. This is the first precision positioning of transition-metal dopants in graphene. The produced graphene-dopant complexes can exhibit atomic-like behavior, inducing desired properties in the graphene. "What could ...

Collaborating with the University of Oxford, Professor Ho Yin Edwin Chan's research team from the School of Life Sciences of The Chinese University of Hong Kong (CUHK) recently unveiled the counteracting relationship between pre-mRNA-processing factor 19 (Prpf19) and exocyst complex component 7 (Exoc7) in controlling the degradation of disease protein and neurodegeneration of the rare hereditary ataxia. The research findings have been published in the prestigious scientific journal, Cell Death & Disease. Protein misfolding contributes to the pathogenesis of SCA3 Proteins play a significant role in every single cell development in the human body, including neurons. Numerous studies have proved that misfolds and aggregation of ...

A new paper by Dr. Miki Ben-Dor and Prof. Ran Barkai from the Jacob M. Alkow Department of Archaeology at Tel Aviv University proposes an original unifying explanation for the physiological, behavioral and cultural evolution of the human species, from its first appearance about two million years ago, to the agricultural revolution (around 10,000 BCE). According to the paper, humans developed as hunters of large animals, causing their ultimate extinction. As they adapted to hunting small, swift prey animals, humans developed higher cognitive abilities, evidenced by the most obvious evolutionary change - the growth of brain volume from ...

A study carried out by researchers from the Institute of Genomics, University of Tartu revealed that human gut microbiome can be used to predict changes in Type 2 diabetes related glucose regulation up to four years ahead. Type 2 diabetes is a metabolic disease characterized by elevated blood glucose levels that contributes to millions of deaths worldwide each year and its prevalence is rapidly increasing. Type 2 diabetes is preceded by "prediabetes" - a condition when the glucose levels have started to rise, but the progression of the disease ...

Takeaway coffees - they're a convenient start for millions of people each day, but while the caffeine perks us up, the disposable cups drag us down, with nearly 300 billion ending up in landfill each year. While most coffee drinkers are happy to make a switch to sustainable practices, new research from the University of South Australia shows that an absence of infrastructure and a general 'throwaway' culture is severely delaying sustainable change. It's a timely finding, particularly given the new bans on single-use plastics coming into effect in South Australia today, and the likelihood of takeaway coffee cups taking ...

Tsukuba, Japan - Single-celled algae and animal sperm cells are widely separated in evolution but both swim in the same way, by waving their protruding hairs, called cilia or flagella. Motion is driven by molecular motors, complex assemblies of proteins that exert a force when changing shape. The motor proteins are connected to the cell's internal skeleton of microtubules; the moving force from the motor causes microtubules to slide, moving the flagella and propelling the cell. Now a team led by Professor Kazuo Inaba of the University of Tsukuba in collaboration with scientists from Osaka University, Tokyo Institute of Technology and Paul Scherrer Institute has described a new protein that is closely ...

While many people believe misinformation on Facebook and Twitter from time to time, people with lower education or health literacy levels, a tendency to use alternative medicine or a distrust of the health care system are more likely to believe inaccurate medical postings than others, according to research published by the American Psychological Association. "Inaccurate information is a barrier to good health care because it can discourage people from taking preventive measures to head off illness and make them hesitant to seek care when they get sick," said lead author Laura D. Scherer, PhD, with the University of Colorado School of Medicine. "Identifying who is most susceptible to misinformation ...

Electric scooters or "e-scooters" are taking over cities worldwide and have broad appeal with tourists. Although e-scooter use declined during the COVID-19 pandemic, its popularity could rebound rapidly, especially if travelers start to substitute scooters for transit on some shorter trips. Shared e-scooters in particular, are a rapidly emerging mode of transportation, but present a host of regulatory challenges from equitable distribution to parking infrastructure to pedestrian safety, among others. Understanding travel demand patterns of shared ...

An associate professor from RUDN University found out the effect of the number and size of pores on the permeability of bone implants by biological fluids. The results of the study could help choose the optimal physical parameters of implants. The results of the study were published in the International Journal of Engineering. For an implant to survive in the body and to take the place of bone tissue, it should be made of a non-toxic, biologically inert, and wearproof material. However, at the same time, it should be light, porous, and permeable by biological liquids. If an implant does not interfere with the transfer of oxygen, minerals, and nutrients, new bone tissue and blood vessels start to grow around it, and a patient's ...

Osaka, Japan - Osaka University researchers employed machine learning to design new polymers for use in photovoltaic devices. After virtually screening over 200,000 candidate materials, they synthesized one of the most promising and found its properties were consistent with their predictions. This work may lead to a revolution in the way functional materials are discovered. Machine learning is a powerful tool that allows computers to make predictions about even complex situations, as long as the algorithms are supplied with sufficient example data. This is especially useful for complicated ...

With their exuberant colours, fiery personalities and captivating courtship displays, the fairy wrasses are one of the most beloved coral reef fish. Despite this, the evolutionary history of its genus was not well understood - until now. Fairy wrasses diverged in form and colour after repeated sea level rises and falls during the last ice age, finds a new study. Published in top journal Systematic Biology, it employed a novel genome-wide dataset to make this discovery. Lead author, ichthyologist and PhD candidate at the University of Sydney, Mr Yi-Kai (Kai) Tea, says ...

Osaka, Japan - Nature is full of diversity, but underneath the differences are often shared features. Researchers from Japan investigating diversity in plant features have discovered that plant root tips commonly converged to a particular shape because of physical restrictions on their growth. In a study published in February in Development, researchers from Osaka University, Nara Institute of Science and Technology, and Kobe University have revealed that plant root tips are constrained to a dome-shaped outline because of restrictions on their tissue growth. This study is one of the papers selected as a Research Highlight published in this issue of Development ...