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Unexpectedly speedy expansion of human, ape cerebellum

2014-10-02
A new study published in the Cell Press journal Current Biology on October 2 could rewrite the story of ape and human brain evolution. While the neocortex of the brain has been called "the crowning achievement of evolution and the biological substrate of human mental prowess," newly reported evolutionary rate comparisons show that the cerebellum expanded up to six times faster than anticipated throughout the evolution of apes, including humans. The findings suggest that technical intelligence was likely at least as important as social intelligence in human cognitive ...

How curiosity changes the brain to enhance learning

2014-10-02
The more curious we are about a topic, the easier it is to learn information about that topic. New research publishing online October 2 in the Cell Press journal Neuron provides insights into what happens in our brains when curiosity is piqued. The findings could help scientists find ways to enhance overall learning and memory in both healthy individuals and those with neurological conditions. "Our findings potentially have far-reaching implications for the public because they reveal insights into how a form of intrinsic motivation—curiosity—affects memory. These findings ...

Stopping liver cancer in its tracks

Stopping liver cancer in its tracks
2014-10-02
This release is available in Japanese. A University of Tokyo research group has discovered that AIM (Apoptosis Inhibitor of Macrophage), a protein that plays a preventive role in obesity progression, can also prevent tumor development in mice liver cells. This discovery may lead to a therapy for hepatocellular carcinoma (HCC), the most common type of liver cancer and the third most common cause of cancer deaths. Professor Toru Miyazaki's group at the Laboratory of Molecular Biomedicine from Pathogenesis, in the Faculty of Medicine has shown that AIM (also known ...

Ancient protein-making enzyme moonlights as DNA protector

Ancient protein-making enzyme moonlights as DNA protector
2014-10-02
LA JOLLA, CA—October 2, 2014—Scientists at The Scripps Research Institute (TSRI) have found that an enzyme best known for its fundamental role in building proteins has a second major function: to protect DNA during times of cellular stress. The finding is remarkable on a basic science level but also points the way to possible therapeutic applications. Strategies that enhance the DNA-protection function of the enzyme, TyrRS, could help protect people from radiation injuries as well as from hereditary defects in DNA repair systems. "We overexpressed TyrRS in zebrafish ...

52-million-year-old amber preserves 'ant-loving' beetle

52-million-year-old amber preserves ant-loving beetle
2014-10-02
Scientists have uncovered the fossil of a 52-million-year old beetle that likely was able to live alongside ants—preying on their eggs and usurping resources—within the comfort of their nest. The fossil, encased in a piece of amber from India, is the oldest-known example of this kind of social parasitism, known as "myrmecophily." Published today in the journal Current Biology, the research also shows that the diversification of these stealth beetles, which infiltrate ant nests around the world today, correlates with the ecological rise of modern ants. "Although ants ...

Counting the seconds for immunological tolerance

Counting the seconds for immunological tolerance
2014-10-02
Our immune system must distinguish between self and foreign and in order to fight infections without damaging the body's own cells at the same time. The immune system is loyal to cells in the body, but how this works is not fully understood. Researchers in the Departments of Biomedicine and Nephrology at the University Hospital and the University of Basel have discovered that the immune system uses a molecular biological clock to target intolerant T cells during their maturation process. These recent findings have been reported in the scientific journal Cell. A functioning ...

DNA 'bias' may keep some diseases in circulation, Penn biologists show

2014-10-02
It's an early lesson in genetics: we get half our DNA from Mom, half from Dad. But that straightforward explanation does not account for a process that sometimes occurs when cells divide. Called gene conversion, the copy of a gene from Mom can replace the one from Dad, or vice versa, making the two copies identical. In a new study published in the American Journal of Human Genetics, University of Pennsylvania researchers Joseph Lachance and Sarah A. Tishkoff investigated this process in the context of the evolution of human populations. They found that a bias toward ...

Study indicates possible new way to treat endometrial, colon cancers

Study indicates possible new way to treat endometrial, colon cancers
2014-10-02
Scientists love acronyms. In the quest to solve cancer's mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. Two examples are ERK (extracellular-signal-related kinase) and JNK (c-June N-Terminal Kinase), enzymes that may offer unexpected solutions for treating some endometrial and colon cancers. A study led by Gordon Mills, M.D., Ph.D., professor and chair of Systems Biology at The University of Texas MD Anderson Cancer Center with Lydia Cheung, Ph.D. as the first author, points to cellular ...

Study gauges humor by age

2014-10-02
Television sitcoms in which characters make jokes at someone else's expense are no laughing matter for older adults, according to a University of Akron researcher. Jennifer Tehan Stanley, an assistant professor of psychology, studied how young, middle-aged and older adults reacted to so-called "aggressive humor"—the kind that is a staple on shows like The Office. By showing clips from The Office and other sitcoms (Golden Girls, Mr. Bean, Curb Your Enthusiasm) to adults of varying ages, she and colleagues at two other universities found that young and middle-aged adults ...

Strong working memory puts brakes on problematic drug use

Strong working memory puts brakes on problematic drug use
2014-10-02
AUDIO: Atika Khurana, assistant professor in the University of Oregon's Department of Counseling Psychology and Human Services, provides a short summary and the implications of a study that looked at the... Click here for more information. EUGENE, Ore. -- Oct. 2, 2014 -- Adolescents with strong working memory are better equipped to escape early drug experimentation without progressing into substance abuse issues, says a University of Oregon researcher. Most important in the picture ...

Sense of invalidation uniquely risky for troubled teens

2014-10-02
PROVIDENCE, R.I. [Brown University] — Among the negative feelings that can plague a teen's psyche is a perception of "invalidation," or a lack of acceptance. A new study by Brown University and Butler Hospital researchers suggests that independent of other known risk factors, measuring teens' sense of invalidation by family members or peers can help predict whether they will try to harm themselves or even attempt suicide. In some cases, as with peers, that sense of invalidation could come from being bullied, but it could also be more subtle. In the case of family, for ...

Socioeconomic factors, fashion trends linked to increase in melanoma

2014-10-02
NEW YORK, NY - A century's worth of cultural and historical forces have contributed to the rise in the incidence of melanoma, including changes in fashion and clothing design, according to an intriguing, retrospective research study conducted by investigators in the Ronald O. Perelman Department of Dermatology at NYU Langone Medical Center. Their findings are the subject of a report, "More Skin, More Sun, More Tan, More Melanoma," in the October 6, 2014 issue of the American Journal of Public Health. The authors surmised that early diagnosis and improved reporting ...

Herbivores play important role in protecting habitats from invasive species

2014-10-02
Champaign Ill. Herbivores (species that eat plants; e.g. caterpillars) consume more non-native (introduced from other places) oak leaf material in areas with diverse native plant communities than in less diverse communities. Why diverse plant communities tend to resist invasion by non-native plants, remains uncertain. Researchers from the Illinois Natural History Survey and the Morton Arboretum have been examining the potential role of herbivores on the invasion of non-native plant species in diverse plant communities. The researchers examined herbivore damage on leaves ...

New report urges caution in handling eyewitness identifications

2014-10-02
WASHINGTON -- A new report from the National Research Council recommends best practices that law enforcement agencies and courts should follow to improve the likelihood that eyewitness identifications used in criminal cases will be accurate. Science has provided an increasingly clear picture of the inherent limits in human visual perception and memory that can lead to errors, as well as the ways unintentional cues during law enforcement processes can compromise eyewitness identifications, the report says. "Human visual perception and memory are changeable, the ability ...

To life! Practicing Judaism could protect against suicide

2014-10-02
In 1897, Emile Durkheim, the father of sociology, speculated that religion could protect against against suicidal impulses. In the century that followed, numerous studies attempted to either prop up or debunk this theory, focusing primarily on Christianity, which condemns suicide as the worst of sins. For the first time, a study published in European Psychiatry approaches Durkheim's premise through the lens of Judaism. According to the research, conducted by Dr. Gal Shoval and Dr. Ben Amit of Tel Aviv University's Sackler School of Medicine and Clalit Health Service's ...

Diet affects mix of intestinal bacteria and the risk of inflammatory bone disease

2014-10-02
(MEMPHIS, Tenn. – October 2, 2014) Diet-induced changes in the gut's bacterial ecosystem can alter susceptibility to an autoinflammatory bone disease by modifying the immune response, St. Jude Children's Research Hospital scientists reported. The findings appeared September 28 as an advanced online publication of the scientific journal Nature. The research provides insight into how the thousands of bacteria and other microorganisms that live in the intestines affect health. The microbes make up the intestinal microbiome, a diverse evolving ecosystem that aids digestion ...

In a bad mood? Head to Facebook and find someone worse off

In a bad mood? Head to Facebook and find someone worse off
2014-10-02
COLUMBUS, Ohio – When people are in a bad mood, they are more likely to actively search social networking sites like Facebook to find friends who are doing even worse than they are, a new study suggests. Researchers found that, in general, people use social media to connect with people who are posting positive and success-oriented updates. "But when people are in a negative mood, they start to show more interest in the less attractive, less successful people on their social media sites," said Silvia Knobloch-Westerwick, co-author of the study and professor of communication ...

To help solve slums, innovators build jobs, food security into affordable housing blueprints

2014-10-02
Building on the poverty relief success achieved through self-sustaining high-tech "smart villages," Malaysian innovators have created blueprints for an urban counterpart that combines affordable homes, food security and sustainable jobs, aiming to solve the growing global problem of squalid city slums. Like the 50-acre smart village sites, the 5-acre urban version provides affordable accommodation with educational and community facilities and incorporates innovative employment opportunities and food security through aquaculture and state-of-the-art water-efficient greenhouse-based ...

On the scent of a wine's bouquet

On the scent of a wines bouquet
2014-10-02
The majority of wines are produced from around 20 different types of grape, all of which have their own typical aroma. This is due to the terpenes, a diverse category of chemical substances including cholesterol and estrogen. Scientists from Technische Universität München (TUM), the Hochschule Geisenheim and the Universität Bonn have now identified two enzymes that determine the terpene content – and thus the aroma intensity – of grapes. The findings could play an important role in the future development of grape varieties. From Chardonnay to Sauvignon, Dornfelder to ...

Parent coaching early intervention program benefits young children with autism

2014-10-02
October 2, 2014 – A parent coaching intervention brings meaningful benefits for preschool-aged children with autism-spectrum disorders (ASD), according to a clinical trial in the October Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The "Play and Language for Autistic Youngsters" (PLAY) Project approach yields improved parent-child interactions, along with other benefits for children with ASD ...

The fat suit study

The fat suit study
2014-10-02
Have you ever ordered more food at a restaurant than you intended? There are elements of dining rooms that actually prime you to eat more food. One such element is the weight of those dining with or near you. This new Cornell University study found that the body type of your dining partner, or that of those dining nearby, may actually influence how much you serve yourself and how much you eat! The study investigated the impact the presence of an overweight diner on healthy and unhealthy food choices and found you are more likely to serve and eat more unhealthy foods ...

New study finds link between depression and abnormal brain response to visceral pain in patients with IBS

New study finds link between depression and abnormal brain response to visceral pain in patients with IBS
2014-10-02
This news release is available in German, Spanish, French and Japanese. High rates of anxiety and depression amongst patients with irritable bowel syndrome (IBS) have led many researchers to believe there could be a causal relationship between psychological factors and IBS symptoms. Now, scientists in Germany have found clear evidence that patients with IBS process pain signals from the gut abnormally, and that disturbed brain responses to pain are particularly pronounced in patients with more depression symptoms.1 At the 22nd United European Gastroenterology ...

HHS releases 13th Report on Carcinogens

HHS releases 13th Report on Carcinogens
2014-10-02
Four substances have been added in the U.S. Department of Health and Human Services 13th Report on Carcinogens, a science-based document that identifies chemical, biological, and physical agents that are considered cancer hazards for people living in the United States. The new report includes 243 listings. Ortho-toluidine, used to make rubber chemicals, pesticides, and dyes, has been reevaluated and is now listed as a known human carcinogen. Three substances have been added as reasonably anticipated to be human carcinogens. These include 1-bromopropane, used as a cleaning ...

Creepy crawlers play key role in structure of grasslands

2014-10-02
When asked to describe a forest or a meadow, most people would probably begin with the plants, the species diversity, or the color of the foliage. They probably wouldn't pay much attention to the animals living in the soil. But a new Yale-led study shows the critical importance of earthworms, beetles, and other tiny creatures to the structure of grasslands and the valuable ecosystem services they provide. During a 3-year study, researchers found that removing these small animals from the soil of a replicated Scottish sheep meadow altered the plant species that grew ...

Marijuana use associated with lower death rates in patients with traumatic brain injuries

2014-10-02
LOS ANGELES – (Oct. 2, 2014) – Surveying patients with traumatic brain injuries, a group of Los Angeles Biomedical Research Institute (LA BioMed) researchers reported today that they found those who tested positive for THC, the active ingredient in marijuana, were more likely to survive than those who tested negative for the illicit substance. The findings, published in the October edition of The American Surgeon, suggest THC, or tetrahydrocannabinol, may help protect the brain in cases of traumatic brain injury, the researchers said. The study included 446 patients who ...
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