Common cholesterol drug greatly alters inflammatory response to common cold
2014-06-02
Cold season may be just behind us, but a new discovery may shed light on how this common condition triggers asthma attacks. In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold. Not only does this discovery suggest that statins could help prevent or reduce the severity of asthma symptoms resulting from colds, but may also open the doors to further research ...
Why some experimental forms of 'The Pill for Males' will never rise to the occasion
2014-06-02
It appears that "The Pill" for men will have to wait a while longer. A new research report published in the June 2014 issue of The FASEB Journal involving mice, shows that a previously developed male hormonal oral contraceptive method (i.e. via testosterone) is unable to stop the production and / or the release of sperm.
"Our research in mice explains why the efficacy of male hormonal contraception is not as effective as expected and it provides clues on how to improve the method," said Ilpo Huhtaniemi, M.D., Ph.D., M.D.hc, FMed.Sci., a researcher involved in the work ...
Early steps toward personalized fitness: Interval training may benefit men more than women
2014-06-02
When it comes to reaping benefits of sprint interval training, it appears that men have won the battle of the sexes, if just barely. According to new research published in the June 2014 issue of The FASEB Journal, men create more new proteins as a result of this exercise than women do. The good news, however, is that men and women experienced similar increases in aerobic capacity. This study is the first to directly measure the creation of proteins made to adapt to this mode of exercise. The study also uniquely used methods that measure the cumulative making of proteins ...
Nano-platform ready: Scientists use DNA origami to create 2D structures
2014-06-02
Scientists at New York University and the University of Melbourne have developed a method using DNA origami to turn one-dimensional nano materials into two dimensions. Their breakthrough, published in the latest issue of the journal Nature Nanotechnology, offers the potential to enhance fiber optics and electronic devices by reducing their size and increasing their speed.
"We can now take linear nano-materials and direct how they are organized in two dimensions, using a DNA origami platform to create any number of shapes," explains NYU Chemistry Professor Nadrian Seeman, ...
Study finds that suicides are far more likely to occur after midnight
2014-06-02
DARIEN, IL – A new study provides novel evidence suggesting that suicides are far more likely to occur between midnight and 4 a.m. than during the daytime or evening.
Results show that the weighted, scaled mean suicide rate per hour was 10.27 percent after midnight, peaking at 16.27 percent between 2 a.m. and 2:59 a.m. In contrast, the mean suicide rate per hour was 2.13 percent between 6 a.m. and 11:59 p.m. When six-hour time blocks were examined, the observed frequency of suicide between midnight and 5:59 a.m. was 3.6 times higher than expected.
"This appears to ...
Antipsychotic medication during pregnancy does affect babies, study shows
2014-06-02
A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies.
The observational study, published in the journal PLOS ONE, reveals that whilst most women gave birth to healthy babies, the use of mood stabilisers or higher doses of antipsychotics during pregnancy increased the need for special care after birth with 43 per cent of babies placed in a Special Care Nursery (SCN) or a Neonatal Intensive Care Unit (NICU), almost three times the national rate in Australia.
As well as an increased likelihood of the need for intensive ...
Neuron tells stem cells to grow new neurons
2014-06-02
DURHAM, N.C. -- Duke researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within.
Neuroscientists have suspected for some time that the brain has some capacity to direct the manufacturing of new neurons, but it was difficult to determine where these instructions are coming from, explains Chay Kuo, M.D. Ph.D., an assistant professor of cell biology, neurobiology ...
Hypnosis extends restorative slow-wave sleep
2014-06-02
Sleeping well is a crucial factor contributing to our physical and mental restoration. SWS in particular has a positive impact for instance on memory and the functioning of the immune system. During periods of SWS, growth hormones are secreted, cell repair is promoted and the defence system is stimulated. If you feel sick or have had a hard working day, you often simply want to get some good, deep sleep. A wish that you can't influence through your own will – so the widely held preconception.
Sleep researchers from the Universities of Zurich and Fribourg now prove ...
Poor sleep equal to binge drinking, marijuana use in predicting academic problems
2014-06-02
DARIEN, IL – A new study shows that college students who are poor sleepers are much more likely to earn worse grades and withdraw from a course than healthy sleeping peers.
Results show that sleep timing and maintenance problems in college students are a strong predictor of academic problems even after controlling for other factors that contribute to academic success, such as clinical depression, feeling isolated, and diagnosis with a learning disability or chronic health issue. The study also found that sleep problems have about the same impact on grade point average ...
NUS scientists demonstrate rare chemical phenomenon to harvest solar energy
2014-06-02
A team of international scientists led by Professor Jagadese J Vittal of the Department of Chemistry at the National University of Singapore's (NUS) Faculty of Science has successfully unraveled the chemical reaction responsible for propelling microscopic crystals to leap distances up to hundreds of times their own size when they are exposed to ultraviolet (UV) light.
This popping effect, akin to the bursting of popcorn kernels at high temperatures, demonstrates the conversion of light into mechanical motion. It is the first instance of a "photosalient effect" driven ...
Half of pregnant women who have hypertension and snore unknowingly have a sleep disorder
2014-06-02
ANN ARBOR, Mich. — 1 in 2 hypertensive pregnant women who habitually snore may have unrecognized obstructive sleep apnea, a sleeping disorder that can reduce blood oxygen levels during the night and that has been linked to serious health conditions, new University of Michigan-led research shows.
One in four hypertensive pregnant women who don't snore also unknowingly suffer from the sleeping disorder, according to the study that appears in the British Journal of Obstetrics and Gynecology.
"We know that habitual snoring is linked with poor pregnancy outcomes for both ...
Marijuana use is associated with impaired sleep quality
2014-06-02
DARIEN, IL – A new study suggests that marijuana use is associated with impaired sleep quality.
Results show that any history of cannabis use was associated with an increased likelihood of reporting difficulty falling asleep, struggling to maintain sleep, experiencing non-restorative sleep, and feeling daytime sleepiness. The strongest association was found in adults who started marijuana use before age 15; they were about twice as likely to have severe problems falling asleep (odds ratio = 2.28), experiencing non-restorative sleep (OR = 2.25) and feeling overly sleepy ...
Even at infancy, human can visually identify objects that stand out: York U study
2014-06-02
TORONTO, June 2, 2014 — Even by three months of age, babies are visually able to locate objects that stand out from a group, a York University study has found.
"For example, an infant can pick a red umbrella in a sea of grey ones," says Psychology Professor Scott Adler in the Faculty of Health, who led the research. "This indicates that babies at a very young age are able to selectively extract information from the environment, just like adults."
Previously it was unknown how early this form of visual attention developed in infants. For the current study, both infants ...
MRSA rates varied dramatically across geographic areas
2014-06-02
LOS ANGELES – (June 2, 2014) – The rates of community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) varied dramatically among academic medical centers in California, New York, Illinois and North Carolina, suggesting there is not a uniform change in the "national epidemic" of the "superbug" that has generated extensive public health concern over the past decade, according to a new study.
The study, published online ahead of print in the journal Clinical Infectious Diseases, surveyed hospital records of 4,171 cases of MRSA and MRSA-related infections between ...
Enzyme used in antidepressants could help researchers develop prostate cancer treatments
2014-06-02
LOS ANGELES (May 30, 2014) – An international team of scientists including researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute and the University of Southern California found that an enzyme commonly used as a target for antidepressants may also promote prostate cancer growth.
The study, published in the Journal of Clinical Investigation, found that suppressing the enzyme monoamine oxidase A, or MAOA, may reduce or even eliminate prostate tumor growth and metastasis in laboratory mice. The finding could open the door for physicians to use antidepressants ...
Virus rounds up enzymes, disarms plant
2014-06-02
University of Tokyo researchers have described how a plant-virus protein suppresses an important plant defense mechanism that remembers viral genetic information, providing a new target for developing the first-ever chemical against plant viruses that globally cause more than $60 billion of crop losses each year.
Invading viruses carry genetic material that hijacks the host cell's machinery, fooling it into producing proteins and new viruses. All cells from fungi to plants and mammals employ RNA silencing, a cellular process essential for the regulation of gene expression ...
New Population Council research presented at 13th ESC Annual Congress
2014-06-02
LISBON, PORTUGAL (31 May 2014) – This week, the Population Council presented new research at the 13th Congress of the European Society of Contraception and Reproductive Health. Presentations included a pharmacokinetic analysis of the Council's investigational one-year contraceptive vaginal ring containing Nestorone® and ethinyl estradiol, and its investigational male contraceptive implant MENT®, as well as new approaches to "green contraception," including strategies to ensure that future contraceptive technologies are both effective and protect the environment.
"The ...
Clinical trial shows drug combination may be effective in recurrent ovarian cancer
2014-06-02
VIDEO:
Dr. Joyce Liu talks about her clinical trial showing drug combination may be effective in recurrent ovarian cancer.
Click here for more information.
CHICAGO –– Significant improvement with the use of a combination drug therapy for recurrent ovarian cancer was reported at the annual meeting of the American Society of Clinical Oncology (ASCO) meeting in Chicago today. This is the first ovarian cancer study to use a combination of drugs that could be taken orally. The ...
New data shows ProMark accurately predicts aggressive prostate cancer, pathology outcomes
2014-06-02
CAMBRIDGE, Massachusetts, June 2, 2014 – Today, for the first time, Metamark presents results from the clinical validation study that showed ProMark™, the first and only proteomic-based imaging biopsy test, achieved its primary endpoint by accurately differentiating between aggressive and non-aggressive forms of prostate cancer at early stages of disease. ProMark™ was shown to predict which patients have low-risk disease with a sensitivity of 90 percent or better, confidently identifying patients who are appropriate for active surveillance or need aggressive therapy. The ...
Study shows tale of 2 prognoses in pediatric brain tumor, pilocytic astrocytoma
2014-06-02
Pilocytic astrocytoma (PA) is a primarily pediatric brain tumor caused mainly by mutations in the BRAF gene. In fact, there are two specific mechanisms for activation of BRAF implicated in PA formation: by fusion of the gene with nearby gene KIAA1549 (K:B fusion) or by point mutations of the BRAF gene itself. Research presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2014 used a newly designed test for K:B fusion to show that point mutations lead to a more dangerous form of the disease than does K:B fusion.
"Overall, the prognosis for Pilocytic ...
DREAM project crowdsources answer to cancer cell drug sensitivities
2014-06-02
A study published June 1 in the journal Nature Biotechnology describes the results of an open challenge to predict which breast cancer cell lines will respond to which drugs, based only on the sum of cells' genomic data. The winning entry, from the Helsinki Institute for Information Technology, was 78 percent accurate in identifying sensitive versus resistant cell lines, and was one of 44 algorithms submitted by groups from around the world.
"The idea is simple – we have this question and anybody can participate in searching for the answer. The question is, do we have ...
A master of disguise: A new stick insect species from China
2014-06-02
Many representatives of the fauna possess unique masking abilities but stick insects are among the masters of disguise within the animal world. During a field trip in Guangxi, China Mr. Ho Wai-chun George from the Hong Kong Entomological Society discovers a new species from this enigmatic insect group, which he describes in a recent research paper published in the open access journal Deutsche Entomologische Zeitschrift.
Like the name suggests the new stick insect Sinophasma damingshanensis is distinguished by peculiarly elongated body and green-brownish coloration, which ...
New species from the past
2014-06-02
A piece of Eocene Baltic Amber of about 45 million years age contains a well preserved extinct flat bug, which turned out to be a new species to science. This exciting discovery is one of the many secrets that deposits of Baltic amber have revealed in the last years and are yet to come in the future. The study describing the new species was published in the open access journal Deutsche Entomologische Zeitschrift.
The new species Aradus macrosomus is a rather large representative of the genus, differing by its size and particular structures from its congeners. The name ...
Same face, many first impressions
2014-06-02
Slight variations in how an individual face is viewed can lead people to develop significantly different first impressions of that individual, according to research published in Psychological Science, a journal of the Association for Psychological Science.
"Our findings suggest that impressions from still photos of individuals could be deeply misleading," says psychological scientist and study author Alexander Todorov of Princeton University.
Previous research has shown that people form first impressions about someone's personality after viewing their face only briefly. ...
What finding out a child's sex before birth says about a mother
2014-06-02
COLUMBUS, Ohio – An expectant mother who chooses to find out her child's sex before birth may be giving subtle clues about her views on proper gender roles, new research suggests.
The study found that women who choose not to learn their child's sex may be more open to new experiences, and combine egalitarian views about the roles of men and women in society with conscientiousness.
On the other hand, expectant mothers who scored high on a test of parenting perfectionism were more likely than others to learn their baby's sex.
"These results suggest women who choose ...
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