Cambridge, MA, April 22, 2014 – Researchers from NeuroPhage Pharmaceuticals, Inc. have engineered a series of molecules with the potential to treat most neurodegenerative diseases that are characterized by misfolded proteins, such as Alzheimer's, Parkinson's and Huntington's diseases. These molecules are based on what the Company calls a general amyloid interaction motif, or GAIM, which recognizes a characteristic common to many toxic, misfolded proteins, not just one type of misfolded protein. This approach provides NeuroPhage with an array of therapeutic targets, so that ...

Researchers at the University of Toronto say a sleep disorder that causes people to act out their dreams is the best current predictor of brain diseases like Parkinson's and Alzheimer's. "Rapid-eye-movement sleep behaviour disorder (RBD) is not just a precursor but also a critical warning sign of neurodegeneration that can lead to brain disease," says associate professor and lead author Dr. John Peever. In fact, as many as 80 to 90 per cent of people with RBD will develop a brain disease." As the name suggests, the disturbance occurs during the rapid-eye-movement (REM) ...

Mysteries of one of the most fascinating nearby planetary systems now have been solved, report authors of a scientific paper to be published by the journal Monthly Notices of the Royal Astronomical Society in its early online edition on 22 April 2014. The study, which presents the first viable model for the planetary system orbiting one the first stars discovered to have planets -- the star named 55 Cancri -- was led by Penn State University graduate student Benjamin Nelson in collaboration with faculty at the Center for Exoplanets and Habitable Worlds at Penn State and ...

HOUSTON – (April 22, 2014) – Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, researchers at Baylor College of Medicine have now been able to categorize the alternative splicing (the process in which genes code proteins, determining their role) that takes place during these changes and what mechanisms they affect. The findings, which appear in Nature Communications, also helped to identify a ...

Brain activity of babies in developing countries could be monitored from birth to reveal the first signs of cognitive dysfunction, using a new technique piloted by a London-based university collaboration. The cognitive function of infants can be visualised and tracked more quickly, more accurately and more cheaply using the method, called functional near infra-red spectroscopy (fNIRS), compared to the behavioural assessments Western regions have relied upon for decades. Professor Clare Elwell, Professor of Medical Physics at University College London (UCL), said: "Brain ...

New research published today out of the University of Calgary's Hotchkiss Brain Institute (HBI) uncovers a mechanism to promote growth in damaged nerve cells as a means to restore connections after injury. Dr. Doug Zochodne and his team have discovered a key molecule that directly regulates nerve cell growth in the damaged nervous system. His study was published in the prestigious journal Nature Communications, with lead authors Drs. Kim Christie and Anand Krishnan. "We made the surprising discovery that a protein called Retinoblastoma (Rb) is present in adult neurons," ...

Trio @ Sam Leong is a 4 story commercial development that consists of retail shops, entertainment outlets and restaurants. Developed by Singapore listed developer Tee Land, this development is strategically located behind Mustafa and is expected to draw traffic with its city fringe location. The nearest MRT is Farrer Park MRT station within a 5 minute walk. A Central Business District (CBD), Orchard Road, Marina Bay Sands is only 10 minutes via train or drive. Trio @ Sam Leong road has a good unit mix of retails shops and restaurants targeted to individual business ...

Alexsyss K. Tylor, better known for hosting the controversial Vagina Power Show and featured appearances on the Maury Povich Show and Comedy Central's Tosh 2.0, branched out into the music industry today by signing Dinero Red, debuting new video. "Dinero RED is an amazing artist and lyricist, whose music is in alignment with my brand. I couldn't be happier to launch this new arm of my business; having Diner RED on board is a dream come true," said Tyler. "This has honestly been such a huge turning point in my music career," announced Dinero RED, " we all know I'm ...

The Daytona Beach Best Western Aku Tiki Inn announces special Easter weekend activities for registered guests. On Saturday April 19th and Sunday April 20th the Best Western Aku Tiki Inn will host a variety of family activities to celebrate the holiday. Events include their annual giant Easter Egg hunt, a Jelly Bean contest, kids will enjoy a visit from the Glitter Tattoo Lady and Benson for his awesome scavenger hunts. On Saturday April 19th families will enjoy creating a beach memory with Magic Milk Sand Art from 11am - 3pm EST and face painting from 5pm - 8pm EST. Travelers ...

Don McCauley of the Free Publicity Focus Group and Danielle Hampson, Executive Producer of The Authors Show, founders of The Authors Marketing Powerhouse, have announced The Authors Show radio and broadcast schedule for the week of April 21, 2014. The new show schedule is available at the Authors Marketing Powerhouse site. For those who hope to sell books on the Internet, the challenge can be daunting. It can be confusing difficult, time consuming and expensive. Book Marketing, branded as The Authors Marketing Powerhouse, helps authors overcome these challenges by providing ...

The Spot Athletics is pleased to announce that their athlete, Jaden Mattox, has won the Junior High State Wrestling Championships for the third straight year. This makes him the 8th wrestler in the history of the Ohio Athletic Committee to win all three years of Junior High.  Along with his state championship he was also awarded the outstanding wrestler trophy for the state tournament. J.L. Holdsworth, Owner of The Spot Athletics, commented on Jaden's success: "Jaden has trained with us year round since he started almost three years ago. Most kids want to take time ...

Elan Carson has been writing since age 6 with the help of her grandmother. The Willow Tree is a dramatic novel that depicts Elan Carson's life growing up with a loved one diagnosed with PTSD (post-traumatic stress disorder). Elan's novel explains how she viewed herself as a child and now a woman in today's society. Elan will discuss her journey and experiences with PTSD on the Dark Mantis Talk show. Elan's descriptive narrative will keep the audience enthralled with every page encountered. The Willow Tree's message is remarkably clear on post-dramatic stress disorder. ...

Fabrice Touil took home $187,290. After an entertaining World Poker Tour main event at the Aviation Club de France, Danish Theo Jorgensen has officially won the tournament. He won the tournament with a pair of aces on the flop, edging out second prize winner Antoine Amourette who came out with a pair of sixes. Jorgensen took home $782,818 while Amourette won $405,906. In third place was Per Linde who won $289,935. Fourth place was taken by Mickael Guenni with a prize pool of $231,949. In fifth place, local Fabrice Touill won $187,290. Touil was rather unlucky in his ...

Fabrice Touil, after the first day of the Legends of Poker 2013 Main Event of France leads the chip count. It was quite an impressive day for Touil as he took in 272,400 chips. While the tournament is far from over, he looks poised to make a deep run as he had a very good showing in the initial stages of the Main Event. The tournament is taking place at the Bicycle Casino in Bell Gardens California. Just behind Touil Were the Americans Ryan A. Goindoo with 269,000 chips, Barry Hutter with 212,400 chips, and Nick Phoenix with 207,700. Currently there are two more ...

It has been widely identified that small businesses such as The Plato Group make a significant contribution to national economies through stimulating the local economy of a country. Small businesses such as The Plato Group help rouse the local economy by bringing growth and innovation to the surrounding community. Small businesses tend to attract talent who invent new products or implement new solutions for existing ideas. Many small businesses also possess the ability to respond and adapt quickly to changing economic climates. This is due to the fact that small businesses ...

According to a new study by Research Now, consumers are more cautious when they are online compared to how they behave offline when it comes to trusting and interacting with brands. Across the research group (2500 regular users of social media in the UK, US and Australia) surveyed, 85% of consumers are more likely to trust a brand if they are in one of its shops or other areas of the 'offline world', than compared to interacting with the brand online. One of the fastest growing methods of direct marketing and advertising in the current economy is event marketing. London ...

Don't miss the boat at Seattle's largest maritime industry celebration! It's the Vigor Seattle Maritime Festival, sponsored by the Seattle Propeller Club and Port of Seattle, on May 10 - 11. In addition to the usual fun of the world's largest tugboat races and workboat parade on the downtown waterfront on Saturday, May 10, this year the Festival expands to Sunday, May 11, with dozens of activities set for Lake Union Park. "By expanding the Festival, we can showcase the working waterfront in Lake Union, the Ship Canal and Fishermen's Terminal," said Rachel Shrewsbury, ...

Playmakers is recognizing the eighth anniversary of Good Form Running and Good Form Walking with a month long celebration in May. Developed by Playmakers in Okemos, Good Form Running (GFR) and Good Form Walking (GFW) are simplified techniques that make running and walking easier and more comfortable for people of all ages and abilities. The proven concepts of GFR and GFW are used by New Balance and are taught in hundreds of locations across the country and internationally. This May, Playmakers will lead a widespread celebration called Good Form month! In addition ...

More than eight out of 10 nurses report that medication cabinets improve efficiency despite having to wait in line at peak times. This and other key findings were released in the latest KLAS report, Medication Cabinets, Carts & BCMA 2014: Technology's Impact on Nurse Efficiency and Patient. Other key findings from the report include the impact carts have on nurse efficiency and patient safety and which medication administration technology is the most widely considered. "Very few nurses disagree on the patient-safety gains of using BCMA," said report author Paul ...

Par4Success offers personalized workouts for golfers of all ages using Titliest Performance Institute (TPI) certified professionals and methods. TPI methods focus on helping a golfer develop an efficient golf swing that protects against potential injuries common in the sport. Using TPI methods along with other research based techniques typically reduces injuries while increasing swing speeds, thus helping the golfer improve their game with less risk of injury. "All of our golf fitness professionals have either been certified by the Titliest Performance Institute and/or ...

The Law Offices of Mathys & Schneid, a Naperville, Illinois, personal injury law firm, is pleased to announce the addition of a second associate. Tyler J. Moore, a lifelong resident of the Chicago area, will devote his practice exclusively to civil litigation. Mr. Moore joins partners Mark W. Mathys and Mark T. Schneid and associate Daniel R. Chaidez. The firm pursues justice for clients who have been injured or lost loved ones due to vehicle accidents, construction accidents, medical malpractice, product defects, and falls and other premises liability cases. The ...

Century Smile provides high quality general dental services in a relaxing environment that focuses on hygiene and comfort. Our experienced team will help you get a brilliant, white smile that improves your overall health and looks. If you are looking for sparkling and dazzling smile, the team at Centurysmile has the experience, tools and technology to help you achieve it. Centurysmile provides an array of dental services including hygiene treatments, porcelain fillings, and crowns-services vital to maintaining a fresh and healthy smile. With our expert Dentist like ...

Moms Fighting Autism and Autism College are partnering up to offer a free virtual conference on Saturday April 26th and Sunday April 27th from 8:00 AM to 5:30 PM PST. This year's theme is: Autism from Adolescence to Adulthood, Preparing for Independence and Growth. Keynote speaker Chantal Sicile-Kira, author of five award-winning books on autism, will be speaking on Preparing for the Transition to Adulthood. Speakers include: Brian King, author of Strategies for Building Successful Relationships with People on the Autism Spectrum, who will speak on "Building a Support Community ...

Advanced Polymer Trading, an international trading company specialising in the world wide trade of rubber and plastics, will be at Interpack 2014, one of the world's most important trade fairs for the packaging sector and related processing industries, which will be held from 8 May 2014 to 14 May 2014 in Dusseldorf, Germany. This year's Interpack event will take up around 174,000 square metres of floor space and host around 2,700 exhibitors from a range of packaging related industries including food and beverages, confectionery and baked goods, pharmaceuticals and cosmetics, ...

The Hampton Inn Gaffney South Carolina Hotel offers a special room rate of $115 per night to guests attending Alumni Weekend at Limestone College April 25-27, 2014. The Alumni Office has reserved a block of rooms. Alumni can reconnect with old friends and classmates as they attend special events throughout the weekend. The activities kick off on Friday evening with Shindig at the Cabin, a community concert in downtown Gaffney. The weekend continues with the Outstanding Alumni Awards Luncheon, Afternoon Tea, All Saints Reunion, campus tours, special exhibits, and Sunday ...