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Medical cannabis provides dramatic relief for sufferers of chronic ailments

2013-01-24
Though controversial, medical cannabis has been gaining ground as a valid therapy, offering relief to suffers of diseases such as cancer, Post-Traumatic Stress Disorder, ALS and more. The substance is known to soothe severe pain, increase the appetite, and ease insomnia where other common medications fail. In 2009, Zach Klein, a graduate of Tel Aviv University's Department of Film and Television Studies, directed the documentary Prescribed Grass. Through the process, he developed an interest in the scientific research behind medical marijuana, and now, as a specialist ...

Cancer expert remains to be convinced by breast screening review

2013-01-24
Michael Baum, Professor emeritus of surgery at University College London says that, while deaths from breast cancer may be avoided, any benefit will be more than outweighed by deaths due to the long term adverse effects of treatment. He estimates that, for every 10, 000 women invited for screening, three to four breast cancer deaths are avoided at the cost of 2.72 to 9.25 deaths from the long term toxicity of radiotherapy. These figures contrast with an independent report on breast cancer screening, led by Sir Michael Marmot and published in November last year. Marmot ...

Tracking the spread of dengue fever: Domestic networks drive rapid transmission of human infection

2013-01-24
The mosquitoes that spread dengue fever tap into the domestic networks of humans, along with their bloodstreams, finds a study recently published in the Proceedings of the National Academy of Sciences (PNAS). The data from Iquitos, Peru, shows that the trail of the most rapid transmission of human infections does not lead through large, public gathering places, as might be expected, but from house-to-house, as people visit nearby friends and relatives. "It's common in a dengue fever outbreak to first treat public places like schools for mosquitoes, but our results show ...

New, cost-cutting approach to formulating pest-killing fungi

2013-01-24
This press release is available in Spanish. Biopesticides containing beneficial fungi are often grown on grains or other solids, but U.S. Department of Agriculture (USDA) scientists have shown a liquid diet can work better. The approach, dubbed "liquid culture fermentation," offers several benefits, including lower material costs and increased yields of certain forms of insect-killing fungi, including Isaria or Metarhizium, which can serve as biobased alternatives to synthetic pesticides. For decades, biopesticide makers have grown such fungi on moistened grains ...

The 3D fireworks of a star

The 3D fireworks of a star
2013-01-24
In 1901 the star GK Persei gave off a powerful explosion that has not stopped growing and astonishing ever since. Now a team of Spanish and Estonian astronomers has reconstructed the journey of the emitted gas in 3D which, contrary to predictions, has hardly slowed down its speed of up to 1,000 km/s after all this time. Thanks to the images captured from the Isaac Newton Telescope and the Nordic Optical Telescope in La Palma (Canary Islands, Spain), a European team of astronomers has constructed a three dimensional map of the remnant of a nova, or in other words, what ...

'Connection error' in the brains of anorexics

2013-01-24
RUB researchers find altered connectivity in the brain network for body perception. The weaker the connection, the greater the misjudgement of body shape When people see pictures of bodies, a whole range of brain regions are active. This network is altered in women with anorexia nervosa. In a functional magnetic resonance imaging study, two regions that are important for the processing of body images were functionally more weakly connected in anorexic women than in healthy women. The stronger this "connection error" was, the more overweight the respondents considered ...

Researchers prevent cancer spread by blocking tissue scarring

2013-01-24
What to fear most if faced by a cancer diagnosis is the spread of the cancer to other parts of the body. This process called metastasis accounts for over 90% of cancer patient deaths and therefore is a strong focus for cancer researchers. Researchers at BRIC, University of Copenhagen have shown that the enzyme Lysyl Oxidase (LOX) can create a "scarred" microenvironment that enhances cancer spreading. By blocking activity of the LOX enzyme, the researchers succeeded in significantly decreasing metastasis in a model of breast cancer. 'When we inhibit the activity of LOX ...

Synthetic corkscrew peptide kills antibiotic-resistant Gram-negative bacteria

2013-01-24
HOUSTON – An engineered peptide provides a new prototype for killing an entire category of resistant bacteria by shredding and dissolving their double-layered membranes, which are thought to protect those microbes from antibiotics. The synthetic peptide was effective in lab experiments against antibiotic-resistant Gram-negative bacteria, which cause a variety of difficult-to-treat, potentially lethal infections such as pneumonia and sepsis. The team led by scientists at The University of Texas MD Anderson Cancer Center reported its findings online in advance of print ...

Introducing 'more patient reality' into NHS spending decisions

2013-01-24
A study by health economists at the University of York has, for the first time, produced an estimate of the impact on other NHS patients of new and more costly drugs and other treatments. This research suggests a refinement of the way the National Institute for Health and Clinical Excellence (NICE) gauges the cost-effectiveness of new interventions. It also has implications for the prices that the NHS can afford to pay for new drugs when the value-based pricing scheme for all new drugs is introduced by the Government in 2014. The project was funded by the Medical Research ...

Pitt team finds 'Achilles Heel' of key HIV replication protein

2013-01-24
PITTSBURGH, Jan. 24, 2013 – Researchers at the University of Pittsburgh School of Medicine may have found an "Achilles heel" in a key HIV protein. In findings published online today in Chemistry and Biology, they showed that targeting this vulnerable spot could stop the virus from replicating, potentially thwarting HIV infection from progressing to full-blown AIDS. Previous research demonstrated that a small HIV protein called Nef interacts with many other proteins in infected cells to help the virus multiply and hide from the immune system. The Pitt group developed a ...

The impact of affirmative action bans in graduate fields of study

2013-01-24
WASHINGTON, January 23, 2013─Important findings on the impact of banning affirmative action in higher education were just published in the American Educational Research Journal (AERJ) in Online First. Affirmative action in university admissions has long been a matter of public debate, and Fisher v. University of Texas, Austin has placed its use in admissions policy as an issue before the U.S. Supreme Court. AERJ is a top-ranked peer-reviewed journal of the American Educational Research Association. The article, "Understanding the Impact of Affirmative Action Bans ...

Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy

2013-01-24
(Philadelphia, PA) - Researchers at Shriner's Hospital Pediatric Research Center at the Temple University School of Medicine, and the University of Pennsylvania have evidence linking the human papillomavirus 16 (HPV16) – the most common cause of cervical cancer – to a common form of childhood epilepsy. They have shown for the first time that HPV16 may be present in the human brain, and found that when they added a viral protein to the brains of fetal mice, the mice all demonstrated the same developmental problems in the cerebral cortex associated with this type of epilepsy, ...

Don't ignore the snore: Snoring may be early sign of future health risks

2013-01-24
DETROIT – Here's a wake-up call for snorers: Snoring may put you at a greater risk than those who are overweight, smoke or have high cholesterol to have thickening or abnormalities in the carotid artery, according to researchers at Henry Ford Hospital in Detroit. The increased thickening in the lining of the two large blood vessels that supply the brain with oxygenated blood is a precursor to atherosclerosis, a hardening of the arteries responsible for many vascular diseases. "Snoring is more than a bedtime annoyance and it shouldn't be ignored. Patients need to seek ...

Can you 'train' yourself to have more willpower?

2013-01-24
PROVIDENCE, R.I. – You can train your body, your mind … and your willpower? That's according to a new study by researchers at The Miriam Hospital's Weight Control and Diabetes Research Center, who say that with a little practice, it may be possible to strengthen and improve your self-control – and lose more weight. The Miriam research team found that individuals with more willpower – or self-control – lost more weight, were more physically active, consumed fewer calories from fat and had better attendance at weight loss group meetings. The same was true for participants ...

Grammar undercuts security of long computer passwords

2013-01-24
PITTSBURGH—When writing or speaking, good grammar helps people make themselves be understood. But when used to concoct a long computer password, grammar — good or bad — provides crucial hints that can help someone crack that password, researchers at Carnegie Mellon University have demonstrated. A team led by Ashwini Rao, a software engineering Ph.D. student in the Institute for Software Research, developed a password-cracking algorithm that took into account grammar and tested it against 1,434 passwords containing 16 or more characters. The grammar-aware cracker surpassed ...

Neuroinflammation may be behind general-anesthesia-associated learning disabilities

2013-01-24
Several studies have found evidence that children who undergo repeated surgical operations with general anesthesia before the age of 4 may be at an increased risk for learning disabilities. In the March issue of Anesthesiology, Massachusetts General Hospital (MGH) researchers report an animal study indicating that several factors – age, the specific anesthetic agent used and the number of doses – combine to induce impairments in learning and memory accompanied by the inflammation of brain tissue. An accompanying paper from the same team finds that the offspring of mice ...

Urban metabolism for the urban century

2013-01-24
New Haven, Conn.–Like organisms, cities need energy, water, and nutrients, and they need to dispose of wastes and byproducts in ways that are viable and sustainable over the long run. This notion of "urban metabolism" is a model for looking systematically at the resources that flow into cities and the wastes and emissions that flow out from them—to understand the environmental impacts of cities and to highlight opportunities for efficiencies, improvements, and transformation. Yale University's Journal of Industrial Ecology is pleased to announce a special issue on Sustainable ...

New dinosaur fossil challenges bird evolution theory

New dinosaur fossil challenges bird evolution theory
2013-01-24
The discovery of a new bird-like dinosaur from the Jurassic period challenges widely accepted theories on the origin of flight. Co-authored by Dr Gareth Dyke, Senior Lecturer in Vertebrate Palaeontology at the University of Southampton, the paper describes a new feathered dinosaur about 30 cm in length which pre-dates bird-like dinosaurs that birds were long thought to have evolved from. Over many years, it has become accepted among palaeontologists that birds evolved from a group of dinosaurs called theropods from the Early Cretaceous period of Earth's history, around ...

Sun shoots out 2 coronal mass ejections

Sun shoots out 2 coronal mass ejections
2013-01-24
VIDEO: This movie shows two coronal mass ejections (CMEs) erupting from the sun on Jan. 23, 2013. The first was not directed at Earth; the second one is, but is not... Click here for more information. On Jan. 23, 2013, at 9:55 a.m. EST, the sun erupted with an Earth-directed coronal mass ejection, or CME. Experimental NASA research models, based on observations from the Solar Terrestrial Relations Observatory (STEREO) and ESA/NASA's Solar and Heliospheric Observatory, show ...

Valuing nature is not enough

2013-01-24
Is it possible to put a price tag on the natural world? A researcher at The University of Nottingham has been examining the rise of a new concept — ecosystem services — to describe the multitude of resources supplied to us by Mother Nature. Academic Dr Marion Potschin, of the University's Centre for Environmental Management, is among an international team of researchers who have been investigating the ethical considerations of this new concept, which some have argued turns nature into a 'commodity'. In a paper published in the journal BioScience, Dr Potschin and her ...

Cells 'flock' to heal wounds

2013-01-24
Like flocks of birds, cells coordinate their motions as they race to cover and ultimately heal wounds to the skin. How that happens is a little less of a mystery today. Researchers once thought only the cells at the edge of a growing patch of wounded skin were actively moving while dividing cells passively filled in the middle. But that's only part of the picture. Rice University physicist Herbert Levine and his colleagues have discovered that the process works much more efficiently if highly activated cells in every part of the patch exert force as they pull their neighbors ...

UCI neuroscientists create fiber-optic method of arresting epileptic seizures

2013-01-24
Irvine, Calif., Jan. 24, 2013 — UC Irvine neuroscientists have developed a way to stop epileptic seizures with fiber-optic light signals, heralding a novel opportunity to treat the most severe manifestations of the brain disorder. Using a mouse model of temporal lobe epilepsy, Ivan Soltesz, Chancellor's Professor and chair of anatomy & neurobiology, and colleagues created an EEG-based computer system that activates hair-thin optical strands implanted in the brain when it detects a real-time seizure. These fibers subsequently "turn on" specially expressed, light-sensitive ...

Mouse menopause model sheds light on UTIs in post-menopausal women

2013-01-24
Researchers from Washington University School of Medicine, St. Louis, show that reservoirs of uropathogenic E. coli within the bladder exist in higher numbers post-menopause than pre-menopause in a mouse model, a finding that could help explain the greater prevalence of urinary tract infections in post-menopausal women. They also found that estrogen supplementation reduced the numbers of such reservoirs dramatically. The research was published online ahead of print in the journal Infection and Immunity. Urinary tract infections (UTIs) afflict an estimated 13 million ...

Vocabulary instruction failing US students

Vocabulary instruction failing US students
2013-01-24
EAST LANSING, Mich. — Vocabulary instruction in the early years is not challenging enough to prepare students for long-term reading comprehension, argues a study led by a Michigan State University education researcher. The study, which appears in Elementary School Journal, analyzed commonly used reading curricula in U.S. kindergarten classrooms. It found that, generally, the programs do not teach enough vocabulary words; the words aren't challenging enough; and not enough focus is given to make sure students understand the meaning of the words. "Vocabulary instruction ...

Research: Lupus drugs carry no significant cancer risk for patients

2013-01-24
This press release is available in French. Montreal, January 24, 2013 – People who take immunosuppressive drugs to treat lupus do not necessarily increase their cancer risk according to new research led by scientists at the Research Institute of the McGill University Health Centre (RI-MUHC). This landmark study, which was published in Annals of the Rheumatic Diseases this month, addresses long-standing fears of a link between lupus medication and cancer. Systemic lupus erythematosus (SLE), commonly known as lupus, is an autoimmune disease in which the body's immune ...
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