Researchers at Emory University School of Medicine have obtained a detailed molecular picture that shows how glucocorticoid hormones shut off key immune system genes. The finding could help guide drug discovery efforts aimed at finding new anti-inflammatory drugs with fewer side effects. The results are scheduled for publication Sunday, Dec. 9 by the journal Nature Structural & Molecular Biology. Synthetic glucocorticoid hormones – for example, prednisone and dexamethasone -- are widely used to treat conditions such as allergies, asthma, autoimmune diseases and cancer. ...

PASADENA, Calif., December 10, 2012 – Children who had in-utero exposure to ischemic-hypoxic conditions, situations during which the brain is deprived of oxygen, were significantly more likely to develop attention deficit hyperactivity disorder later in life as compared to unexposed children, according to a Kaiser Permanente study published in the journal Pediatrics. The findings suggest that events in pregnancy may contribute to the occurrence of ADHD over and above well-known familial and genetic influences of the disorder. The population-based study examines the association ...

WINSTON-SALEM, N.C. – Dec. 10, 2012 – When you're postmenopausal and overweight, losing weight is a good thing, but gaining back just a few pounds may actually be detrimental to your cardiovascular health. New research from Wake Forest Baptist Medical Center found that gaining weight back after intentional weight loss is associated with negative long-term effects on some cardiometabolic (CM) risk factors in postmenopausal women. In this paper, published online by the Journal of Gerontology: Medical Sciences, lead authors Daniel Beavers, Ph.D., and Kristen Beavers, Ph.D., ...

For three years, University of Utah researchers have been deploying a computer-based design program called SketchUp in workshops to teach and develop life skills for youth on the autism spectrum. An earlier study showed that using the program helps kids develop their spatial and visual acuity, as well as to leverage those strengths to build positive social interactions. In the latest analysis of experiences from the educational workshops, researchers have found that using the technology also helps open new communication doors with grandparents of the students. The shared ...

Sara Stablein, named 2011 Southwestern Pro of the Year by the U.S. Professional Tennis Association (USPTA), has joined The Bridges at Rancho Santa Fe as its new Tennis Director. Stablein will oversee instruction and programming at The Bridges' $5 million Tennis & Recreation Centre, a five-acre facility serving club members and their children and grandchildren. "Sara is not only an accomplished competitor but she has proven herself as an effective and innovative club director," said The Bridges General Manager Sean McCune, who noted that Stablein spent ...

Forget about Chicago, the biggest toddlin' town around is Montessori International School's Toddler House, 2447 Fairbrook Road and the Toddler Community at 2401 E. Brown Road, both in Mesa. Tots from 12 months to three years of age play with puzzles, don plastic coats and paint, sit in a circle and sing, learn Spanish, and interact happily with one another. A visit to either school denotes a surprisingly calm environment. While the occasional unhappy camper may surface, for the most part the school is free of the sound of whining and the smell of disinfectant that permeates ...

The first bit of advice that a parent will receive from the school system if a child is struggling with reading is that the child needs a tutor. Parents have been listening to this advice for so long that they actually believe it. Stop listening to those that say you can't be helpful and take on the 31 day reading challenge for yourself. All you need to do is read every day for 31 days with your child. If you are looking for tips each day, then there is a new book that was just released called 31 Days to Become a Better Reader: Increasing your Struggling Reader's Reading ...

Today, Pure Hedonist Omnimedia President and Editorial Director Letitia Elizabeth announced the launch of Lillie, a bi-monthly hybrid fashion + food magazine for a new class of woman who cares deeply about the impact her personal style choices have on the environment. Lillie fills a void in the marketplace with substance, wit and unwavering respect for sustainable design and craftsmanship. Created for the nostalgic, modern and highly discerning woman, the magazine play's on women's desire to showcase their personal tastes without sacrificing lifestyle standards. This is ...

The city of Cambridge, Minnesota, its Economic Development Division, and Golden Shovel Agency have teamed up together to launch an online web solution, Economic Gateway. The purpose of the website is to raise awareness of the area of Cambridge, MN and all that it has to offer to its residents, current and future business enterprises, and site selectors. The new site can be viewed at http://ci.cambridge.mn.us/. John Marshall, Vice President of Business Development at Golden Shovel explains that "Cambridge has taken a very progressive step in partnering with Golden ...

The Association of Management Consulting Firms has elected P. Michael Saint, chairman and CEO of The Saint Consulting Group, to the organization's Board of Directors. Mr. Saint is founder of The Saint Consulting Group, the world's largest and most experienced firm in the management consulting discipline of land use politics. He is co-author of the book, NIMBY Wars - The Politics of Land Use, published in 2009. Saint Consulting has offices in Hingham, MA, Nashville, Chicago and San Ramon, CA, and international affiliates in Toronto, Vancouver, London and Berlin. The ...

An article published by Search Engine Journal has detailed the factors that lead to success in the area of content marketing. A seasoned veteran of the writing and editing industry, Amanda E. Clark, manages a team of professionals who create compelling content on a daily basis. She commented on the piece in a statement to the press. Competent marketers recognize the key elements that make a content marketing strategy stand out. The article states that by acknowledging audience members' desire for a narrative, content marketers can create the emotion of sentiment and ...

Rated #1 in customer support for the last 3 years in a row, SoftInWay's engineers offer 24/365 support to their clients! In addition to demoing the AxSTREAM Software Suite, the team will share their experiences with recent and complicated ORC / Super Critical CO2 Cycle designs and demonstrate strategies for leveraging their advanced software tools, training and engineering consulting services for their customers to beat the competition. SoftInWay will also share the recently published training program schedule for the first half of 2013. Attendees will be able to pick ...

Trex Company, the industry leading manufacturer of wood-alternative decking and railing products, has recently named digital agency Cuker Interactive as their "Digital Agency of Record." Trex will partner with Cuker Interactive to lead their online marketing initiatives, beginning with a complete redesign of Trex.com. Trex Company is the world's largest manufacturer of high performance wood-alternative decking and railing, with products stocked in over 5,500 retail locations worldwide. Trex's high quality, low maintenance outdoor living products offer unsurpassed ...

If we were to eavesdrop and listen in while the "Father of Medicine" Hippocrates spoke to his students in 400 B.C., we would hear him saying: "Let thy food be thy medicine and thy medicine be thy food."  These words ring even more true today, when WorldHealth.net reports that each year prescription drugs injure 1.5 million people to the degree that they require hospitalization. Sleeping drugs, also known as "hypnotics", come with their own set of side-effects.  For those who seek natural options, some recent research studies have uncovered ...

Jackpot Capital Casino is travelling the globe this holiday season with its $85,000 'Around the World' Scoreboard competition. Five locations in five weeks! Players that make it to the contest's final travel destination can win BIG casino bonuses. Nearly $20,000 in prizes will be awarded every Monday until January 14th and every "Hump Day" there's another chance to win casino bonus money when up to 100 players will get Surprise Wednesday Bonuses. A total of over $85,000 in casino bonuses will be given away before the holiday travel adventure is over. Jackpot ...

According to a recent article from The New York Times the path of destruction caused by recent Superstorm Sandy "unearthed fuel tanks, ravaged cooling towers and battered air-conditioners" causing affected building and business owners to consider a new alternative for these scenarios--geothermal energy. Although not a leader in comparison to oil and gas usage, geothermal exploration has provided a great addition to America's energy resources. The article states, "Geothermal energy systems, common in countries like Iceland and China, use the constant temperature ...

According to Cancun Cosmetic Dentistry complaints from patients regarding cosmetic appearances have easily been addressed by the advances made available from businesses participating in the medical and dental tourism markets. The trusted Mexico-based facility notes that many seek cosmetic procedures in foreign countries not only for a way to recover in a peaceful destination, but also to receive high-level care at a fraction of the cost found in America and Canada. However, according to an article from PeterGreenberg.com, these practices are becoming more prevalent not ...

Many drivers simply pay their traffic fines with the hope to avoid the consequences of these charges, unaware that many of the charges could follow them for year or even increase their auto insurance rates. Traffic tickets can become an expensive and time-consuming legal battle for drivers that try to contest these charges without the help of an experienced Orange county traffic ticket lawyer. CheapTrafficAttorneys.com is now offering legal assistance for all traffic charges throughout Orange County. For many traffic tickets, the initial fines seem like a reasonable ...

With close to $180 billion in assets, 529 plans have become the primary college-savings vehicle for most parents and grandparents. If you haven't yet opened up an account in a 529 plan, follow these seven steps and you will be on your way to financing your child's future college expenses and reducing student debt. 1. Pick the plan. You don't have to choose your own state's 529 plan--but perhaps you should. Check to see if your state offers some extra perks--like a state tax deduction, matching contribution, or expense waiver--that you lose with an out-of-state 529 ...

Rocky Mountain Tanners is a wholesale leather provider that offers leather from a variety of game animals, including leather made from elk skin, deer skin, and American Bison/buffalo hides. These leathers are difficult to find at leather retailers and specialty shops. Rocky Mountain Tanners sells these leathers pre-tanned at affordable prices. Elk leather is a historical tradition in the American West. For centuries, Native Americans and mountain men alike have sought elk skins to tan and make into leather. Leather made from elk hides continues to be in high demand among ...

Smiles LA, East Los Angeles dental office, recently announced that they will be offering smile makeovers to both new and established patients. Smiles LA is delighted to offer a range of services designed to enhance the natural beauty of an individual's smile. In today's climate, possessing a luminous smile confers benefits to an individual in both professional and personal dealings. Dr. Elyson, East Los Angeles dentist, explains the benefits a smile makeover accords including restored function to chewing and speaking, plus an elevated mood due to an increased desire ...

Alpine Sales and Rental Corporation offers rock cutting, soil remediation and trenching equipment for all construction and mining needs. Alpine's rock and concrete cutters use technology derived from the mining industry to create powerful, highly versatile hydraulic cutting tools that can provide an alternative to the traditional hammer. With carbide teeth and precision cutting capabilities, Alpine's cutter heads are available in a wide variety of sizes and shapes to match virtually any job at hand, including cutting and grinding rock, concrete and more. Alpine's soil ...

Certification is one of the most important steps in a lawyer's professional life. As part of their commitment to maintaining high standards in their practice, partners Mitch Panter, Brett Panter and David Sampedro have all achieved board certification by the Florida Bar. Continuing education is extremely important, especially for our partners who are passionate about their careers and about helping people, and who do everything in their power to maintain their high standards of professionalism and knowledge. Board certification is the highest level of evaluation for ...

St. Louis, Missouri Auto Accident Attorney Daniel P. Finney, Jr., of the Finney Law Office, LLC, has been selected to the American Society of Legal Advocates. Finney is known for his tireless work representing victims of car accidents, trucking accidents, medical negligence and other personal injury claims. The American Society of Legal Advocates limits their selection to less than 2% of all attorneys nationwide. ASLA membership is by invitation only and seeks to select attorneys from all practice areas. Finney was chosen for his specialty in litigating personal injury ...

The Defense of Marriage Act (DOMA) was signed into law in 1996. Now, 16 years later, the law is being challenged in both the courts and the polling booths. As noted in the New York Times, high courts in New York and Connecticut have held DOMA as unconstitutional and a violation of the equal protection clause of the Constitution. In addition to the judicial system taking action, voters also made their opinions clear in several states during this past election. DOMA Defined DOMA, in short, defines marriage as being between one man and one woman. The federal act means ...