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Risk of death significantly higher if both mother and newborn admitted to ICU following birth

2012-10-22
Mothers and newborns who are both admitted to an intensive care unit (ICU) after delivery are significantly more likely to die compared with mom–baby pairs not needing ICU admission, found a study in CMAJ (Canadian Medical Association Journal). As well, when both mother and baby require admission to an ICU, they are much more likely to be managed at different hospitals, thereby negatively impacting maternal–infant bonding. Researchers completed a population-based study of all 1.02 million live born singleton deliveries in Ontario between 2002 and 2010. They found that ...

Healthy behaviors in midlife significantly increase odds of successful aging

2012-10-22
Engaging in a combination of healthy behaviours, such as not smoking, moderate alcohol consumption, exercise, and eating fruits and vegetables daily makes it significantly more likely people will stay healthy as they age, according to a study published in CMAJ (Canadian Medical Association Journal). "Our study shows the cumulative impact of healthy behaviours on successful aging — the greater the number of healthy behaviours, the greater the benefit," writes Dr. Séverine Sabia, Department of Epidemiology and Public Health, UCL (University College London), UK, with coauthors. Successful ...

Kinesin 'chauffeur' helps HIV escape destruction

Kinesin chauffeur helps HIV escape destruction
2012-10-22
A study in The Journal of Cell Biology identifies a motor protein that ferries HIV to the plasma membrane, helping the virus escape from macrophages. HIV reproduces inside disease-fighting T cells, killing them in the process. But the virus can also replicate in macrophages, which survive infection and serve as reservoirs of HIV. In T cells, new viral particles are formed at the plasma membrane, but in macrophages the viruses assemble inside cytoplasmic containers called virus-containing compartments (VCCs). To break out of a macrophage, a virus particle therefore has ...

New research highlights changing epidemiology of Clostridium difficile

2012-10-22
Las Vegas, NV (October 22, 2012) – A stay in the hospital may not be the only way to acquire Clostridium difficile diarrhea – but the potentially life-threatening infection may be associated with a number of health complications in hospitalized children, according to the findings from two studies unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. In a separate case report also presented today, fecal microbiota transplantation in a 20-month old with recurrent Clostridium difficile infection (CDI) suggests the therapeutic ...

Studies explore racial disparities in IBD symptoms and therapy

2012-10-22
Las Vegas, NV (October 22, 2012) –Three separate studies presented today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas help to advance understanding of the differences between African American and Caucasian patients with Inflammatory Bowel Disease (IBD) and provide clinicians with new insight on how racial disparities involving disease characteristics, infliximab use, and fistulizing Crohn's disease may impact their patients—and their decisions on how best to manage the disease. The incidence of inflammatory bowel disease ...

A whale with a distinctly human-like voice

2012-10-22
AUDIO: This audio clip captures the unusual speech-like sounds from white whale NOC. See supplemental information for more data. Click here for more information. For the first time, researchers have been able to show by acoustic analysis that whales—or at least one very special white whale—can imitate the voices of humans. That's a surprise, because whales typically produce sounds in a manner that is wholly different from humans, say researchers who report their findings in the ...

For African beetles, dung balls double as 'air conditioning units'

2012-10-22
Some African dung beetles roll their feasts of dung away to avoid the hordes of other hungry bugs at the pile. But now researchers who report their findings in the October 23 issue of Current Biology, a Cell Press publication, have discovered that the beetles also use the balls in another, rather clever way: The moist balls keep the bugs cool even as they push a weight up to 50 times heavier than their own bodies across the scorching sand. "Like an air conditioning unit, the moist ball is cooled by evaporative cooling," said Jochen Smolka of Lund University. "The beetles ...

Improving the safety of angioplasty in patients with coronary bypass graft disease

2012-10-22
(PHILADELPHIA) – Researchers at Thomas Jefferson University Hospital have shown that combining distal protection devices with the prophylactic use of the drug nicardipine is more effective at preventing life-threatening complications following a percutaneous coronary intervention (PCI) (angioplasty, stenting) on patients who have undergone previous bypass surgery than distal protection devices alone. Their findings will be presented on Tuesday, October 23rd, at 8 a.m. at the Transcatheter Cardiovascular Therapeutics (TCT) conference, at the Miami Beach Convention Center ...

ACG 2012 features new insights on esophageal cancer, trends in C. difficile, GI bleeding mortality

2012-10-22
Las Vegas, NV (October 22, 2012) – Many of the world's preeminent gastroenterologists have convened this week for the American College of Gastroenterology's (ACG) 77th Annual Scientific Meeting at The Venetian Resort, Las Vegas, NV to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management. New technologies for treating conditions like gastroesophageal reflux (GERD), Irritable Bowel Syndrome (IBS) and gastroparesis; groundbreaking insights in inflammatory bowel disease (IBD) that explore racial ...

Beetles use dung balls to stay cool

Beetles use dung balls to stay cool
2012-10-22
Dung beetles roll their feasts of dung away to avoid the hoards of other hungry competitors at the dung pile. But now a team of researchers from South Africa and Sweden have discovered that they also use their balls in another, rather clever way. The moist balls keep the beetles cool even as they push a weight up to 50 times heavier than their own bodies across the hot sand. "The beetles climb on top of their moist balls whenever their front legs and heads overheat," said Prof. Marcus Byrne from Wits University. "We stumbled upon this behaviour by accident while watching ...

Studies suggest possible overlap of IBS symptoms and inflammatory bowel disease

2012-10-22
Las Vegas, NV (October 22, 2012) – Research unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas suggests a possible overlap of symptoms of two prevalent GI disorders: irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) and further suggests a possible link between subtle GI tract inflammation and IBS symptoms—a link that is also the focus of the first systemic review of the literature on this topic and an editorial both published in this month's American Journal of Gastroenterology. One study ...

Selenium deficiency may cause cardiomyopathy post-gastric bypass

2012-10-22
Las Vegas, NV (October 22, 2012) –-Non-compliance with vitamin and mineral supplementation protocols after bariatric surgery could lead to nutritional deficiencies and related health complications, such as heart damage, according to two separate case reports unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. Case Report 1: "Malnutrition Secondary to Non-Compliance with Vitamin and Mineral Supplements after Gastric Bypass Surgery: Complex Problem, Simple Solution" Multivitamin supplementation is considered ...

Chronic constipation linked to increased risk of colorectal cancer

2012-10-22
Las Vegas, NV (October 22, 2012) – Patients with chronic constipation may be at increased risk of developing colorectal cancer and benign neoplasms, according to study findings unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. The study, "Risk of Developing Colorectal Cancer and Benign Neoplasm in Patients with Chronic Constipation," investigated the prevalence and incidence of colorectal cancer and benign neoplasms in 28,854 patients with chronic constipation (CC) and 86,562 controls without CC that ...

Increased colorectal cancer risk for extended family members, younger endometrial cancer patients

2012-10-22
Las Vegas, NV (October 22, 2012) – Women under age 50 who have been diagnosed with endometrial cancer, and first, second and third degree relatives of patients with colorectal cancer may have an increased risk of developing colorectal cancer (CRC), according to two separate studies unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. Two other CRC-related studies presented at ACG 2012 investigated the impact of gender, race and obesity on the incidence of adenoma and advanced adenoma detection rates—suggesting ...

Risks of esophagus cancer studied: Statins may protect against esophageal cancer

2012-10-22
Las Vegas, NV, (October 22, 2012) – Statin use is associated with protection from esophagus cancer according to a new meta-analysis of existing clinical studies exploring the cancer prevention effects of statins presented by a Mayo Clinic researcher, Dr. Siddharth Singh, at the American College of Gastroenterology 77th Annual Scientific Meeting in Las Vegas, NV. Dr. Singh and his Mayo colleagues conducted a systematic review of eleven studies reporting 8,613 cases of esophageal cancer from studies including almost 1 million patients. Incidence of esophageal cancer ...

Type 2 diabetes may increase the risk of Barrett's esophagus

2012-10-22
Las Vegas, NV (October 22, 2012) – Patients with Type 2 Diabetes may face an increased risk for Barrett's Esophagus (BE), regardless of other risk factors including smoking, alcohol consumption, obesity and gastroesophageal reflux disease (GERD), according to research unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. The study, "Diabetes Mellitus Increases the Risk of Barrett's Esophagus: Results from A Large Population Based Control Case Study," suggests that, "if you have diabetes, your risk for Barrett's ...

Death from GI bleeding decreased in United States in past 2 decades

2012-10-22
Las Vegas, NV (October 22, 2012) – The number of patients dying from upper gastrointestinal bleeding has decreased over the past two decades, a result researchers attribute to the advances in medical and endoscopic therapies introduced over the past 20 years, according to a report unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. One example of how such advances are impacting patient care is described in a separate case report also presented today on the first use of Hemospray™ (Cook Endoscopy) that saved the ...

Marijuana use may cause severe cyclic nausea, vomiting, a little-known, but costly effect

2012-10-22
Las Vegas, NV (October 22, 2012) – Marijuana use—both natural and synthetic—may cause cannabinoid hyperemesis (CH) a little-known but costly effect that researchers suggest is a serious burden to the health care system as it often leads to expensive diagnostic tests and ineffective treatments in an effort to find the cause of a patient's symptoms and provide relief, according to two separate case reports unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. Cannabinoid hyperemesis is characterized by a history of ...

New technologies and endoscopic techniques emerge to address gastrointestinal disorders

2012-10-22
Las Vegas, NV, (October 22, 2012) – Advances in endoscopic technologies and techniques will be highlighted in clinical research presented at the 77th Annual Scientific Meeting of the American College of Gastroenterology in Las Vegas, NV. A Press Briefing with experts on these topics is scheduled for Monday October 22, at 12:45 pm Pacific Daylight Time by dialing toll-free 888-850-4523 (participant code 424049). A new scarless option to treat rare swallowing disorder, achalasia Enhancements in a technique known as NOTES (natural orifice transluminal endoscopic surgery) ...

Chronic electrical stimulation at acupressure points may relieve stomach woes for diabetics

2012-10-22
Las Vegas, NV (October 22, 2012) – Diabetic patients who suffer from a common complication of diabetes called gastroparesis may find that chronic electrical stimulation (ES) at specific acupuncture points could relieve gastroparesis symptoms such as nausea, vomiting, early satiety, abdominal fullness, upper abdominal pain and bloating, according to study results unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas. The study, "Chronic Electrical Stimulation at Acupuncture Points Improves Dyspeptic Symptoms," ...

Electrical stimulation of the esophagus promising treatment for unresolved reflux symptoms

2012-10-22
Las Vegas, NV, (October 22, 2012) – Clinical evidence of the safety and effectiveness of electrical stimulation of a muscular valve in the esophagus demonstrates promising results in resolving symptoms of gastroesophageal reflux (GERD) and is being presented at the 77th Annual Scientific Meeting of the American College of Gastroenterology in Las Vegas, NV. Three studies examined small numbers of patients who had a device implanted that uses low energy electrical pulses to strengthen a weak or dysfunctional lower esophageal sphincter (LES) which is the underlying cause ...

Wits part of study that discovers a unique feature of HIV that helps to create antibodies

2012-10-22
Wits researchers have played a pivotal role in an AIDS study published today in the journal, Nature Medicine, which describes how a unique change in the outer covering of the virus found in two HIV infected South African women enabled them to make potent antibodies which are able to kill up to 88% of HIV types from around the world. This ground-breaking discovery provides an important new approach that could be useful in making an AIDS vaccine. The study, performed by members of the Centre for the Aids Programme of Research in South Africa (CAPRISA) consortium, involves ...

New test may uncover deadly hypertension disease in pregnancy

New test may uncover deadly hypertension disease in pregnancy
2012-10-22
SANTA BARBARA – Collaborators at Cottage Health System and University of California, Santa Barbara (UCSB) have identified biomarkers that may yield a revolutionary diagnostic test for pre-eclampsia, a complex and potentially life-threatening hypertensive condition affecting 5% of pregnancies worldwide. The most common dangerous complication of pregnancy, pre-eclampsia is potentially fatal and often mimics or is confused with other pregnancy-related conditions—such as swelling, gastric pain, and high blood pressure. Pre-eclampsia can lead to eclampsia, which carries a ...

Scientists seek national wildlife conservation network

2012-10-22
Fairbanks, Alaska--Wildlife conservation efforts in the United States are facing habitat loss, climate change and major reductions in funding. To address these threats, a group of prominent wildlife biologists and policy experts is recommending the formation of a state-based national conservation-support network. Their proposal is published in the November issue of the journal BioScience. "We surveyed wildlife managers from every state and territory to assess the state of the wildlife conservation system," said co-author Brad Griffith, a wildlife biologist with the U.S. ...

Astronomers study 2 million light year 'extragalactic afterburner'

2012-10-22
Blasting over two million lights years from the centre of a distant galaxy is a supersonic jet of material that looks strikingly similar to the afterburner flow of a fighter jet, except in this case the jet engine is a supermassive black hole and the jet material is moving at nearly the speed of light. Research published over the weekend in the Astrophysical Journal Letters shows the galaxy-scale jet to have bright and dark regions, similar to the phenomenon in an afterburner exhaust called 'shock diamonds.' A new image of the previously studied jet reveals regularly ...
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