Social determinants of health and the availability of cancer clinical trials in the US
2024-05-07
About The Study: Substantial geographic disparities in cancer clinical trials availability exist throughout the United States, with the most socially vulnerable counties being far less likely to have any trial and having only a fraction of trials available, a disparity that has worsened over time.
Corresponding Author: To contact the corresponding author, Rishi Robert Sekar, M.D., M.S., email rsekar@med.umich.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.10162)
Editor’s Note: Please ...
Multilevel characteristics of cumulative symptom burden in young survivors of childhood cancer
2024-05-07
About The Study: The findings of this study suggest that symptoms are prevalent years after young childhood cancer survivors’ initial cancer diagnosis, and interventions to reduce caregiver anxiety and neighborhood adversity and improve resilience may alleviate symptom burden.
Corresponding Author: To contact the corresponding author, I-Chan Huang, Ph.D., email i-chan.huang@stjude.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.10145)
Editor’s Note: Please see the article for additional information, ...
Why getting in touch with our ‘gerbil brain’ could help machines listen better
2024-05-07
Macquarie University researchers have debunked a 75-year-old theory about how humans determine where sounds are coming from, and it could unlock the secret to creating a next generation of more adaptable and efficient hearing devices ranging from hearing aids to smartphones.
In the 1940s, an engineering model was developed to explain how humans can locate a sound source based on differences of just a few tens of millionths of a second in when the sound reaches each ear.
This model worked on the theory that we must ...
It flickers, then it tips – study identifies early warning signals for the end of the African humid period
2024-05-07
The transition from the African Humid Period (AHP) to dry conditions in North Africa is the clearest example of climate tipping points in recent geological history. They occur when small perturbations trigger a large, non-linear response in the system and shift the climate to a different future state, usually with dramatic consequences for the biosphere. That was also the case in North Africa, where the grasslands, forests, and lakes favored by humans disappeared, causing them to retreat to areas like the mountains, oases, and the Nile Delta. This ...
Aquatic weed among ‘world’s worst’ expands in Northeastern US
2024-05-07
WESTMINSTER, Colorado – 7 May 2024 – An article in the latest issue of Invasive Plant Science and Management provides new insights on a northern hydrilla (Hydrilla verticillata) subspecies (lithuanica) and its establishment outside the Connecticut River. Considered among the “world’s worst” aquatic weeds, northern hydrilla hinders recreational activities by forming dense canopies. If unchecked, it has the potential to displace native species and host a bacterium that produces ...
Emergency department packed to the gills? Someday, AI may help
2024-05-07
UCSF-led study finds artificial intelligence is as good as a physician at prioritizing which patients need to be seen first.
Emergency departments nationwide are overcrowded and overtaxed, but a new study suggests artificial intelligence (AI) could one day help prioritize which patients need treatment most urgently.
Using anonymized records of 251,000 adult emergency department (ED) visits, researchers at UC San Francisco evaluated how well an AI model was able to extract symptoms from patients’ ...
Asthma education is key to reducing deaths worldwide, say respiratory health associations
2024-05-07
NEW YORK, NY - May 7, 2024 – On World Asthma Day 2024 the message is clear: "Asthma Education Empowers." The Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, stresses the crucial role of education in empowering people with asthma to manage their condition effectively and to know when to seek medical assistance.
FIRS also urges health care professionals to enhance their awareness of the preventable morbidity and mortality from asthma and of the published evidence on effective asthma management, so they are equipped to provide reliable information and optimal treatment for their patients.
Asthma ...
60% of women with disabilities view cannabis as a ‘harmless’ drug
2024-05-07
A growing number of states and territories in the United States have legalized medical and recreational cannabis use. As such, recreational cannabis has been associated with a lower perception of risk of harm in the general U.S. population.
However, in women of childbearing age, evidence has shown that cannabis use may increase the risk of adverse reproductive and perinatal health outcomes. Furthermore, research on the perception of risk from using cannabis among vulnerable populations such as those with disabilities is lacking.
Using data from the 2021 National Survey on Drug Use and Health, researchers from Florida ...
Years after his death, late scientist's work could yield new cancer treatments
2024-05-07
Some of the final work of a late University of Virginia School of Medicine scientist has opened the door for life-saving new treatments for solid cancer tumors, including breast cancer, lung cancer and melanoma.
Prior to his sudden death in 2016, John Herr, PhD, had been collaborating with UVA Cancer Center’s Craig L. Slingluff Jr., MD, to investigate the possibility that a discovery from Herr’s lab could help treat cancer.
Eight years of research has borne that idea out: Herr’s research into the SAS1B protein could lead to “broad and profound” new treatments ...
SwRI evaluates reliability of pressure relief valves for liquid natural gas tanks in train derailment scenarios
2024-05-07
SAN ANTONIO — May 7, 2024 —Southwest Research Institute (SwRI) has helped determine the viability of pressure relief valves for liquid natural gas tanks in the event of a train derailment for the Federal Rail Administration (FRA). The report from the FRA shows that a study conducted by SwRI demonstrates that the pressure relief valves work as designed to prevent overpressurization and explosion if a derailment occurs.
“The pressure relief valves on tanks that transport liquid ...
Study: You’re breathing potential carcinogens inside your car
2024-05-07
The air inside all personal vehicles is polluted with harmful flame retardants—including those known or suspected to cause cancer—according to a new peer-reviewed study published in Environmental Science & Technology. Car manufacturers add these chemicals to seat foam and other materials to meet an outdated federal flammability standard with no proven fire-safety benefit.
“Our research found that interior materials release harmful chemicals into the cabin air of our cars,” said lead author Rebecca ...
Using AI to predict GPA from college application essays
2024-05-07
Jonah Berger and Olivier Toubia used natural language processing to understand what drives academic success. The authors analyzed over 20,000 college application essays from a large public university that attracts students from a range of racial, cultural, and economic backgrounds and found that the semantic volume of the writing, or how much ground an application essay covered predicted college performance, as measured by grade point average. Essays that covered more semantic ground predicted higher grades. Similarly, essays with smaller conceptual jumps between successive parts of ...
Few tenure-track jobs for engineering PhDs
2024-05-07
A study finds that most engineering PhD graduates will never secure a tenure-track faculty position. Over the past 50 years, the number of full-time faculty positions in US universities has steadily declined while production of science and engineering PhD graduates has nearly doubled. Siddhartha Roy and colleagues analyzed data on PhD graduates and tenure-track and tenured faculty members across all engineering disciplines from 2006–2021. The average annual likelihood of securing a tenure-track faculty position in engineering during this 16-year period was 12.4%. The likelihood of securing a tenure-track faculty position was 18.5% in ...
Hidden citations in physics
2024-05-07
In the scientific literature, a citation acts as a mechanism to signal prior knowledge, enhance credibility, and protect against plagiarism. But it also gives credit to the individual or team who established or discovered the knowledge in question, and citations have thus emerged as a metric to measure the impact of a work or researcher. However, when a discovery or technique becomes common knowledge, scientists often stop bothering to cite it. Thus, the most impactful work is often undercited. Albert-László Barabási ...
Wildfire risk management in the era of climate change
2024-05-07
A Perspective explores lessons learned from recent deadly wildfires and proposes a strategy for managing wildfire risk. Wildfire risk and wildfire deaths are on the rise due to climate change, policies of fire suppression, and development in the wildland-urban interface. The August 8, 2023, fire that destroyed the historic town of Lahaina, Hawaii, claimed 98 lives, in part due to a failure to alert residents to the danger. In 2018, 104 lives were lost in a fire in Mati, Greece, for which there were also no alerts. For both ...
A smart neckband for tracking dietary intake
2024-05-07
A smart neckband allows wearers to monitor their dietary intake. Automatically monitoring food and fluid intake can be useful when managing conditions including diabetes and obesity, or when maximizing fitness. But wearable technologies must be able to distinguish eating and drinking from similar movements, such as speaking and walking. Chi Hwan Lee and colleagues propose a machine-learning enabled neckband that can differentiate body movements, speech, and fluid and food intake. The neckband’s sensor module includes ...
Gut bacteria metabolite shows promise of fighting inflammatory bowel disease
2024-05-07
Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health. Any disturbance in the gut microbiota can, therefore, have a systemic impact. Intestinal microbes metabolize dietary components into beneficial fatty acids (FAs), supporting metabolism and maintaining host body homeostasis. Metabolites originating from polyunsaturated fatty acids (PUFAs), influenced by gut microbes such as Lactobacillus plantarum, exhibit potent effects on ...
Breakthrough paves the way for next generation of vision implants
2024-05-07
A group of researchers from Chalmers University of Technology in Sweden, University of Freiburg and the Netherlands Institute for Neuroscience have created an exceptionally small implant, with electrodes the size of a single neuron that can also remain intact in the body over time – a unique combination that holds promise for future vision implants for the blind.
Often when a person is blind, some or part of the eye is damaged, but the visual cortex in the brain is still functioning and waiting for ...
New study finds increase in exposures to synthetic tetrahydrocannabinols among young children, teens, and adults
2024-05-07
(COLUMBUS, Ohio) – A sharp rise in exposures to synthetic cannabis products among youth — some leading to hospitalization — highlights the need for increased education around the dangers of exposure and increased focus on safe storage and packaging, according to pediatricians and researchers at Nationwide Children’s Hospital and the Central Ohio Poison Center.
A new study conducted by researchers at the Center for Injury Research and Policy of the Abigail Wexner Research Institute at Nationwide Children’s Hospital and the Central Ohio Poison Center examined trends in calls to poison ...
Dogma-challenging telomere findings may offer new insights for cancer treatments
2024-05-07
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.
PARP1’s job is genome surveillance: When it senses breaks or lesions in DNA, it adds a molecule called ADP-ribose to specific proteins, which act as a beacon to recruit other ...
Scientists cooked pancakes, Brussels sprouts, and stir fry to detect an oxidant indoors for the first time
2024-05-07
A feast cooked up by UBC researchers has revealed singlet oxygen indoors for the first time.
Oxi-don’t
Singlet oxygen is an oxidant. These chemical compounds can be beneficial—ozone in the stratosphere is one example—but can also cause stress to our lungs, contributing to the development of cancer, diabetes, and heart disease in the long term.
Cooking foods can release brown carbon, molecules with the potential to create oxidants when they absorb light. In addition, exposure to cooking emissions has been linked to chronic diseases in chefs.
Historically, it was thought there wasn’t enough light indoors to have much ...
Quantum breakthrough: World’s purest silicon brings scientists one step closer to scaling up quantum computers
2024-05-07
More than 100 years ago, scientists at The University of Manchester changed the world when they discovered the nucleus in atoms, marking the birth of nuclear physics.
Fast forward to today, and history repeats itself, this time in quantum computing.
Building on the same pioneering method forged by Ernest Rutherford – "the founder of nuclear physics" – scientists at the University, in collaboration with the University of Melbourne in Australia, have produced an enhanced, ultra-pure form of silicon that allows ...
New super-pure silicon chip opens path to powerful quantum computers
2024-05-07
Researchers at the Universities of Melbourne and Manchester have invented a breakthrough technique for manufacturing highly purified silicon that brings powerful quantum computers a big step closer.
The new technique to engineer ultra-pure silicon makes it the perfect material to make quantum computers at scale and with high accuracy, the researchers say.
Project co-supervisor Professor David Jamieson, from the University of Melbourne, said the innovation – published today in Communication Materials, a Nature journal – uses qubits of phosphorous atoms implanted ...
Millions in costs due to discharge of scrubber water into the Baltic Sea
2024-05-07
Discharge from ships with so-called scrubbers cause great damage to the Baltic Sea. A new study from Chalmers University of Technology, Sweden, shows that these emissions caused pollution corresponding to socio-economic costs of more than EUR 680 million between 2014 and 2022. At the same time, the researchers note that the shipping companies' investments in the much-discussed technology, where exhaust gases are "washed" and discharged into the sea, have already been recouped for most of the ships. This means that the industry is now making billions ...
Bio-inspired materials’ potential for efficient mass transfer boosted by a new twist on a century-old theory
2024-05-07
The natural vein structure found within leaves – which has inspired the structural design of porous materials that can maximise mass transfer – could unlock improvements in energy storage, catalysis, and sensing thanks to a new twist on a century-old biophysical law.
An international team of researchers, led by the NanoEngineering Group at the Cambridge Graphene Centre, has developed a new materials theory based on ‘Murray’s Law’, applicable to a wide range of next-generation functional ...
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