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Healthy lifestyle and cognition in older adults with common neuropathologies of dementia

2024-02-05
About The Study: This study found that in older adults, a healthy lifestyle may provide a cognitive reserve to maintain cognitive abilities independently of common neuropathologies of dementia. Authors: Klodian Dhana, M.D., Ph.D., of Rush University Medical Center in Chicago, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2023.5491) Editor’s Note: Please see the article for additional information, including other authors, ...

Officer-involved killings of unarmed black people and racial disparities in sleep health

2024-02-05
About The Study: Sleep duration among Black survey respondents worsened after exposure to officer-involved killings of unarmed Black individuals in their area of residence. The findings were specific to officer involved killings of unarmed Black people, and no adverse outcomes on sleep health were found for white respondents. These findings underscore the role of structural racism in shaping racial disparities in sleep health.  Authors: Atheendar S. Venkataramani, M.D., Ph.D., of the University ...

Injuries from legal interventions involving conducted energy devices

2024-02-05
About The Study: This study of emergency department visits for physical injuries from use of conducted energy devices, such as TASERs, by police departments found that most visits involved young Black and white males from low-income areas. Black individuals were overrepresented in the sample versus the U.S. population, consistent with research demonstrating increased risk of police violence in Black populations.  Authors: Kevin N. Griffith, Ph.D., of the Vanderbilt University Medical Center ...

Losing sleep over killings of unarmed Black individuals by police

2024-02-05
PHILADELPHIA – Black adults across the United States suffer from sleep problems following exposure to news about unarmed Black individuals killed by police during police encounters, according to new findings published today in JAMA Internal Medicine from researchers at the University of Pennsylvania Perelman School of Medicine. The issue, researchers said, may compound the risk factors that poor sleep already poses for many chronic and mental health conditions, from depression to post traumatic stress disorder. Researchers conducted two separate analyses examining changes in sleep duration in the U.S. non-Hispanic Black population before and after exposure to such deaths ...

New technology unscrambles the chatter of microbes

2024-02-05
Researchers from University of California San Diego, as part of a large collaboration with scientists around the world, have developed a new search tool to help researchers better understand the metabolism of microorganisms. Microbes are key players in virtually all biological and environmental systems, yet limitations in current techniques used to study microbial metabolism make it difficult to decode their interactions and activities. The new research, published February 5, 2023 in Nature Microbiology, directly addresses these limitations, which could ultimately transform our understanding of both human health and the environment. “Humans are walking ecosystems in which microbes vastly ...

Pulmonary rehabilitation is difficult for millions of Americans to access

2024-02-05
New Haven, Conn. — Pulmonary rehabilitation, an essential component of care for patients with chronic respiratory conditions, is difficult for millions of Americans to access, a new Yale-led study reveals. The findings, researchers say, reveal geographic regions where this type of care is most lacking and illustrate the potential for telemedicine in helping to bridge this gap. The study was published Feb. 5 in JAMA Network Open. Pulmonary rehabilitation is a multidisciplinary program that incorporates exercise and strategic techniques to improve quality of life and overall health for patients with respiratory conditions like chronic ...

Bacterial test for raw, organic milk may require more precision

2024-02-05
ITHACA, N.Y. -- Cornell food scientists show that a standard quality test used for raw, organic milk is insufficient for distinguishing between specific groups of bacteria, suggesting that the criteria for determining milk quality at processing plants needs to be updated. Their work was published Jan. 20 in the Journal of Dairy Science. “Testing milk should not be one size fits all,” as tests should be used appropriately to give the best feedback to dairy producers, said lead author Renee Lee ’21, ...

Brazilian researcher helps describe a novel species of jellyfish discovered in a remote location in Japan

Brazilian researcher helps describe a novel species of jellyfish discovered in a remote location in Japan
2024-02-05
A gelatinous animal with a diameter of about 10 cm and a red stomach resembling the Cross of St George when seen from above. This is Santjordia pagesi, a newly described species of medusa. Medusae are a type of free-swimming, umbrella-shaped jellyfish with a reduced stalk. The new species is described in an article published in the journal Zootaxa. The study was conducted by an international group of researchers that included a Brazilian scientist supported by FAPESP.  The scientist in question is André Morandini, last author ...

Small but mighty – study highlights the abundance and importance of the ocean’s tiniest inhabitants

2024-02-05
Tiny plankton – measuring less than 20µm (or 0.02mm) in diameter – make up the majority of plankton in the ocean and play a critical role in the planet’s health, according to new research. However, scientists say challenges in identifying them have led to them becoming a silent majority that is currently being overlooked when it comes to global ocean policy. The study is one of the first to explore the abundance and importance of these tiny ocean inhabitants around the UK coastline, with the technology capable of monitoring them only having been introduced in around 2010. However, ...

Bullied teens’ brains show chemical change associated with psychosis

Bullied teens’ brains show chemical change associated with psychosis
2024-02-05
Researchers have found that adolescents being bullied by their peers are at greater risk of the early stages of psychotic episodes and in turn experience lower levels of a key neurotransmitter in a part of the brain involved in regulating emotions. The finding suggests that this neurotransmitter — a chemical messenger that transmits nerve impulses for communication by a nerve cell — may be a potential target for pharmaceutical interventions aimed at reducing the risk of psychotic disorders. Psychosis is a mental state characterized by loss of contact with reality, incoherent speech and behavior, and typically hallucinations and delusions seen in psychiatric disorders ...

Unlocking precision medicine for inflammatory bowel disease

Unlocking precision medicine for inflammatory bowel disease
2024-02-05
The prevalence of inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is rapidly increasing worldwide, affecting an estimated 6.8 million people. This surge brings significant economic burdens, with annual healthcare costs exceeding $12,000 and $7,000 for CD and UC patients, respectively. Tailored drug selection based on individual factors can potentially reduce these costs and improve patient outcomes. Factors associated with a Western lifestyle such as urbanization, high animal protein intake, ultra-processed foods, and reduced fiber ...

High production of polyols using crude glycerol by wild-type safe yeasts

2024-02-05
Utilizing crude glycerol for the synthesis of high-value products offers a promising solution to counter the adverse effects of declining glycerol prices in the biodiesel sector. The prevalence of crude glycerol, a by-product of biodiesel production, across agriculture, biofuel, and industrial sectors is steadily rising. Recent advancements have demonstrated the effectiveness of both wild-type and mutant yeast strains as microbial cell factories capable of converting glycerol into a diverse array of valuable compounds, including microbial oils, sugar-alcohols (polyols), and organic acids. With the projected increase in biodiesel production, there is a need to explore integrated ...

Solvent sieve method sets new record for perovskite light-emitting diodes

Solvent sieve method sets new record for perovskite light-emitting diodes
2024-02-05
Using a simple solvent sieve method, researchers from the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) have taken the lead in developing highly efficient and stable perovskite light-emitting diodes (PeLEDs) with record performance. The study was published in Nature Photonics. Perovskites are one of the most promising optoelectronic materials due to their excellent optoelectronic performance and low preparation cost. Compared with traditional organic light-emitting diodes (OLEDs), PeLEDs have a narrower light-emitting spectrum and superior color ...

Combination therapy lowers blood pressure in patients receiving ibrutinib

2024-02-05
(WASHINGTON, Feb. 5, 2024) – Combination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutinib, according to a new study published in Blood Advances. Targeted drugs such as ibrutinib have improved outcomes for patients with cancers of the lymphatic system, but patients treated with ibrutinib and other drugs in its class often develop new or worsening high blood pressure (or hypertension or HTN). Few studies have examined how best to treat this potentially serious side effect, nor do any formal guidelines exist to steer doctors toward the most effective treatments. “To ...

Ultra-sensitive lead detector could significantly improve water quality monitoring

Ultra-sensitive lead detector could significantly improve water quality monitoring
2024-02-05
Engineers at the University of California San Diego have developed an ultra-sensitive sensor made with graphene that can detect extraordinarily low concentrations of lead ions in water. The device achieves a record limit of detection of lead down to the femtomolar range, which is one million times more sensitive than previous sensing technologies. “With the extremely high sensitivity of our device, we ultimately hope to detect even the presence of one lead ion in a reasonable volume of water,” said Prabhakar Bandaru, a professor in the Department of Mechanical and Aerospace Engineering at the UC San Diego Jacobs School of Engineering. “Lead exposure is a serious health concern, ...

World’s largest childhood trauma study uncovers brain rewiring

2024-02-05
The world’s largest brain study of childhood trauma has revealed how it affects development and rewires vital pathways.     The University of Essex study – led by the Department of Psychology’s Dr Megan Klabunde – uncovered a disruption in neural networks involved in self-focus and problem-solving.    This means under-18s who experienced abuse will likely struggle with emotions, empathy and understanding their bodies.     Difficulties in school caused by memory, hard mental tasks and decision making may also emerge.    Dr ...

Number of shark bites consistent with recent trends, with small spike in fatalities

Number of shark bites consistent with recent trends, with small spike in fatalities
2024-02-05
There was an increase in the number of unprovoked shark attacks worldwide and an uptick in fatalities in 2023 compared to the previous year. The University of Florida’s International Shark Attack File (ISAF), a scientific database of global shark attacks, confirmed 69 unprovoked bites in 2023. Although this is higher than the most recent five-year average of 63 attacks, the data remain consistent with long-term trends. Ten of the past year’s unprovoked attacks were fatal, up from five the year before, with a disproportionate number occurring in Australia. Although the country accounted for 22% of all attacks, ...

Schmidt Sciences awards $1.95M gift to Mount Sinai's Windreich Department of Artificial Intelligence and Human Health to establish The Eric and Wendy Schmidt AI in Human Health Fellowship Program

2024-02-05
New York, NY (February 5, 2024) — The Windreich Department of Artificial Intelligence (AI) and Human Health at the Icahn School of Medicine at Mount Sinai announced a transformative $1.95 million gift from Schmidt Sciences to create The Eric and Wendy Schmidt AI in Human Health Fellowship Program. The gift will support an inaugural cohort of five fellows over a three-year fellowship. By leveraging AI and machine learning to tackle the increasing volume of data in health care, The Eric and Wendy Schmidt AI in Human Health Fellows will play a pivotal role in advancing medical research. ...

NFL PLAY 60 Fitness Break broadcast delivers movement minutes in advance of Super Bowl LVIII

2024-02-05
DALLAS, Feb. 5, 2024 — The American Heart Association and the National Football League (NFL), in collaboration with its 32 NFL clubs, are challenging kids to get moving and PLAY 60 in advance of Super Bowl LVIII with the latest installment of the NFL PLAY 60 Fitness Break broadcast series. On Thursday, February 8 at 1 p.m. ET/ 12 p.m. CT/ 10 a.m. PT the Association and the NFL will deliver an action packed, 15-minute synchronous broadcast to help students add movement to their day leading up to the big game along with ...

Microbial division of labor produces higher biofuel yields

Microbial division of labor produces higher biofuel yields
2024-02-05
CHAMPAIGN, Ill. — Scientists have found a way to boost ethanol production via yeast fermentation, a standard method for converting plant sugars into biofuels. Their approach, detailed in the journal Nature Communications, relies on careful timing and a tight division of labor among synthetic yeast strains to yield more ethanol per unit of plant sugars than previous approaches have achieved. “We constructed an artificial microbial community consisting of two engineered yeast strains: a glucose specialist and a xylose specialist,” said Yong-Su Jin, a professor of food science and human nutrition ...

Fencing young mussels for ecosystem restoration

Fencing young mussels for ecosystem restoration
2024-02-05
The restoration of mussel beds in the Wadden Sea or the Delta is a lot more successful when young mussels are helped a little with low, protective fences on the bottom. That is shown by research conducted by marine biologist Jildou Schotanus at the Hogeschool Zeeland / University of Applied Sciences in Vlissingen and at the Royal Netherlands Institute for Sea Research in Yerseke. She defends her thesis Restoring mussel beds on highly dynamic mudflats at the University of Groningen on Monday February 5th. Ecosystem engineers Mussels are so-called ecosystem ...

Mild Covid-19 infections make insomnia more likely, especially in people with anxiety or depression

2024-02-05
Although most patients diagnosed with Covid-19 will quickly recover, some people experience symptoms that linger well after they start testing negative again — including insomnia. Scientists already knew that insomnia was common in patients who had to be hospitalized, but a team of scientists led by Dr Huong T. X. Hoang of Phenikaa University, Vietnam began to wonder if mild infections might also affect sleep quality. “As a sleep researcher, I received many questions and complaints from relatives, friends, ...

Winners of the 2024 Hill Prizes announced

Winners of the 2024 Hill Prizes announced
2024-02-05
Hill Prize in Medicine Awarded to Martin M. Matzuk, M.D., Ph.D. (NAS), Baylor College of Medicine Hill Prize in Engineering Awarded to Maria A. Croyle, Ph.D., The University of Texas at Austin Hill Prize in Biological Sciences Awarded to Russell A. DeBose-Boyd, Ph.D. (NAS), UT Southwestern Medical Center Hill Prize in Physical Sciences Awarded to Allan H. MacDonald, Ph.D. (NAS), The University of Texas at Austin Hill Prize in Technology Awarded to Hermann Lebit, Ph.D., Alma Energy February 5, 2024 – Austin – TAMEST ...

Beyond the pedals: testing upper limb feasibility of cardiopulmonary exercise testing

Beyond the pedals: testing upper limb feasibility of cardiopulmonary exercise testing
2024-02-05
How can inclusivity be achieved in cardiopulmonary exercise tests for individuals facing lower limb injuries or disabilities that make it impossible to pedal a bicycle? Conventional exercise assessments rely primarily on lower limb exercise to determine maximal oxygen uptake – a cardiopulmonary function metric that indicates the maximum amount of oxygen that can be taken into the body in one minute. If lower limbs cannot be exercised, it necessitates an upper limb alternative. However, no clear upper limb ...

Making drug use less dangerous for users is the only way to tackle overdose epidemic

2024-02-05
With more than 100,000 drug overdose deaths in the United States in one year, communities need more than ‘just say no’ drug prevention education and abstinence-only addiction treatment to save lives, an expert has warned. Statistics show that most people who complete conventional drug prevention education as youth eventually go on to use alcohol, nicotine, or illegal drugs. Harm reduction expert Sheila P. Vakharia, PhD, MSW, explains: “The majority have experimented, others use socially, and some experience substance-related problems or addictions. And, regardless of their patterns of use, most have never been taught strategies for safer substance use, ...
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