In a study of nearly 200 young women who have survived breast cancer, most of those who tried to conceive were able to become pregnant and give birth   This study fills in major gaps from previous studies of fertility among breast cancer survivors   BOSTON – New research by Dana-Farber Cancer Institute investigators has encouraging news for young women who have survived breast cancer and want to have children. The study, which tracked nearly 200 young women treated for breast cancer, found that the majority of those who tried to conceive during a median of 11 years after treatment were able to become pregnant and give birth to a child. The findings, ...

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), will share results of their work in 30 presentations at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which takes place May 31 – June 4 in Chicago. The clinical trials reported on in this work are led by SWOG and conducted by the NIH-funded NCI National Clinical Trials Network (NCTN) and the NCI Community Oncology Research ...

ABSTRACTS: 2018, 2517, 3513, 5504, 6016, 7007, 9515, 12017, LBA8007, LBA9516 CHICAGO ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This special edition features presentations by MD Anderson researchers at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. In addition to the ...

Dae Hyun Kim, MD, ScD is the recipient of a 2024 A. Clifford Barger Excellence in Mentoring Award at Harvard Medical School. Kim is an associate scientist at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, an HMS Associate Professor of Medicine, a geriatrician at the Division of Gerontology in the Department of Medicine at Beth Israel Deaconess Medical Center, and a Harvard School of Public Health Instructor in the Department of Epidemiology. The Excellence in Mentoring Awards were established to recognize the value of quality mentoring ...

The results in Nature Communications find that symbiotic, nitrogen-fixing bacteria can ensure dominance among soil microbes due to its signalling-based communication with the legume plant host. Researchers discovered that when legumes need nitrogen, they will send out from the roots and into the soil specific molecules that are in turn recognized by the symbiotic bacteria to produce another molecule, the Nod factor which is recognized back by the legume plant. When this mutual recognition was established, the plant will modify the panel of root secreted molecules and by this will affect which soil bacteria can grow in the vicinity ...

­­­Colleen Ryan, associate vice provost in the Office of the Vice Provost for Faculty & Academic Affairs Indiana University Bloomington (IUB), has been named vice provost for faculty at Tufts University. She will start in the position on July 1. Ryan currently holds the rank of professor of Italian in the Department of French and Italian at IUB, is an affiliate faculty member in the Department of Gender Studies, and was the director of undergraduate studies for Italian from 2015-2023. Her areas of expertise ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain’s biological pathways and cellular functions. The research, supported the National Institutes of Health (NIH), used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple ...

URBANA, Ill. – Parents are often eager to give their adolescent children advice about school problems, but they may find that youth are less than receptive to their words of wisdom. However, kids who don’t seem to listen to their parents may still benefit from their input, a new study from the University of Illinois Urbana-Champaign shows. The researchers looked at conversations between fifth-grade students and their mothers about academic problems, identifying mom’s advice strategies and the youth’s response. Then they correlated these findings with how ...

News Release Journal of Raptor Research For immediate release   Contact: [Zoey T. Greenberg] science.writer@raptorresearchfoundation.com 360.739.7170   Parents of the Year: Scavenging Raptors Lead a Collaborative Home Life    Let’s face it, scavengers have a bad reputation. However, according to a new paper published in the Journal of Raptor Research, pairs of scavenging falcons called Chimango Caracaras (Milvago chimango) demonstrate an endearing level of collaboration while raising their chicks. In their paper, “Biparental Care in a Generalist Raptor, the Chimango Caracara in Central Argentina” Diego Gallego-García from ...

Deciphering the genetic causes of common neurodevelopmental conditions like autism and common mental illnesses like bipolar disorder has been challenging – not least because of the size and complexity of the human brain – but a new package of research from a global group makes notable progress. Across Science, Science Translational Medicine, and Science Advances, more than a dozen reports from the PsychENCODE Consortium – established in 2015, and dedicated to illuminating the molecular ...

Study combines analyses of multiple genomic platforms over multiple brain regions to probe biological processes and underlying mechanisms of stress-related disorders Results lay groundwork for future diagnostics and targeted treatments BELMONT, Mass. (May 23, 2024) A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the  Mass General Brigham healthcare system, ...

CORVALLIS, Ore. – What if a common element rather than scarce, expensive ones was a key component in electric car batteries? A collaboration co-led by an Oregon State University chemistry researcher is hoping to spark a green battery revolution by showing that iron instead of cobalt and nickel can be used as a cathode material in lithium-ion batteries. The findings, published today in Science Advances, are important for multiple reasons, Oregon State’s Xiulei “David” Ji notes. “We’ve transformed the reactivity of iron metal, the cheapest metal commodity,” he said. “Our electrode can offer a higher energy density ...

BELMONT, Mass. (May 23, 2024) Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging. In a new study, published May 23 is Science, a team led by McLean Hospital researchers used comprehensive genetic and cellular analyses to shed new light on the intricate molecular mechanisms underlying schizophrenia. Their new work provides a map for how the genes known to increase risk of schizophrenia affect specific cells within the brain. “We discovered which cell types express ...

The world’s population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022. These numbers underscore the need for considering family planning; however, there have been limited breakthroughs in contraception in recent decades. Specifically for men, there are no oral contraceptive pills available. In a study published in the journal Science, researchers at Baylor College of Medicine and collaborating institutions show in animal models that a novel, non-hormonal sperm-specific approach offers a promising option ...

Artificial intelligence approaches demonstrate how plant science has evolved Machine learning also reveals how model systems have changed and how countries differ in terms of research focus and impact ##### In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology:   http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002612 Article Title: Assessing the evolution of research topics in a biological field using plant science as ...

Using the James Webb Space Telescope, University of Copenhagen researchers have become the first to see the formation of three of the earliest galaxies in the universe, more than 13 billion years ago. The sensational discovery contributes important knowledge about the universe and is now published in the prestigious journal Science. For the first time in the history of astronomy, researchers at the Niels Bohr Institute have witnessed the birth of three of the universe's absolute earliest galaxies, somewhere between 13.3 and 13.4 billion years ago.  The ...

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease, as reported by researchers from the University of Basel and the University Hospital Basel in the journal Science. Exactly 60 years ago, pathologist Anthony Epstein and virologist Yvonne Barr announced the discovery of a virus that has carried their names ever since. The Epstein-Barr virus (EBV) made scientific history as the first virus proven to cause cancer in humans. Epstein and Barr isolated the pathogen, ...

New Haven, Conn. – A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer’s disease.  The findings, reported May 23 in Science, were the result of a multi-institutional collaboration known as PsychENCODE, founded in 2015 by the National Institutes of Health, which seeks new understandings of genomic influences on neuropsychiatric disease. The study was published alongside related studies in Science, Science Advances, and Science ...

AUSTIN, Texas — Stress-related disorders like post-traumatic stress disorder and clinical depression are complex conditions influenced by both genetics and our environment. Despite significant research, the molecular mechanisms behind these disorders have remained elusive. However, researchers at Dell Medical School at The University of Texas at Austin have broken new ground with a study that sheds light on the intricate differences occurring in the brains of people with PTSD and depression compared to neurotypical controls. The study, published this week in Science, could provide potential avenues for novel therapeutics and biomarkers. “Understanding why some people develop ...

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24. These investigations, conducted with colleagues from other major research centers, involve the largest single-cell analysis to date of the brains of people with schizophrenia, and a first-of-its-kind ...

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain. This novel dataset provides crucial insights into the molecular basis of neurodevelopmental and psychiatric brain disorders and paves the way for targeted therapies. The research, published in Science, also details how transcript expression varies by cell type and maturity, finding that changing gene-isoform expression levels can help ...

Researchers from Carnegie Mellon University's School of Computer Science will contribute to two multi-institution research initiatives aimed at reducing the use of carbon and creating sustainable computing. The projects recently received funding through the U.S. National Science Foundation's (NSF) Expeditions in Computing Awards program, which is providing $36 million to three projects selected for their potential to revolutionize computing and make significant impacts toward reducing the carbon footprint of the lifecycle of computers. The ...

By John Lovett University of Arkansas System Division of Agriculture FAYETTEVILLE, Ark. — It’s not just for burritos and popcorn. Microwave technology is also being tested as a new tool to destroy weed seeds and decrease herbicide use. Scientists and engineers with the Arkansas Agricultural Experiment Station are investigating the use of 915 MHz microwaves to neutralize a variety of weed seeds underground. The study is supported by a nearly $300,000 Agriculture and Food Research Initiative grant from the U.S. Department of Agriculture’s National Institute of Food and Agriculture, with additional support ...

Tafadzwa Chaunzwa, MD, a  researcher in the Artificial Intelligence in Medicine (AIM) Program at Mass General Brigham and a senior resident physician at the Harvard Radiation Oncology Program, is the lead author of a paper published in JAMA Oncology. Chaunzwa and senior author Hugo Aerts, PhD, director of the AIM Program, and associate professor at Harvard University, shared highlights from their paper. How would you summarize your study for a lay audience? As treatments like immunotherapy improve cancer survival rates, there is a growing need for clinical decision-support tools that predict treatment response ...

In a recent study, researchers from the Charles Darwin Foundation (CDF), in collaboration with the Guy Harvey Research Institute (GHRI) and Save Our Seas Foundation Shark Research Center (SOSF-SRC) at Nova Southeastern University in Florida, and the Galapagos National Park Directorate (GNPD) have documented the most extensive migration ever recorded for a silky shark (Carcharhinus falciformis), revealing critical insights into the behavior of this severely overfished species and emphasizing the urgent need for cooperative international management measures to prevent further population declines. The ...