DePuy Orthopaedics announced in August 2010, that it is voluntarily recalling its ASR Hip Replacement System used in hip replacement surgery due to the number of patients who required a second hip replacement procedure, called "revision surgery." New, unpublished 2010 data from the National Joint Registry (NJR) of England and Wales shows a five-year revision rate of approximately 12% for the hip resurfacing system and approximately 13% for the acetabular system. Kevin J. Bozic, MD, an orthopaedic surgeon and vice chair of orthopaedics at the University of California ...

The National Highway Traffic Safety Administration (NHTSA) estimates that one in every six fatal car accidents results from a fatigued driver. This statistic shows why New Jersey's law that criminalizes drowsy driving is necessary to combat the problem of over-tired drivers. In a study by the AAA Foundation for Traffic Safety, 41 percent of the drivers surveyed admitted to having fallen asleep at the wheel. Also, more than a quarter of the drivers reported that within the last month they drove despite being so tired that they had trouble keeping their eyes open. Drowsy ...

In 2008, many predicted that the recession would have a negative effect on marriages, as job losses and mounting debt would lead to more divorces. The divorce rate has steadily declined in the last two years, but the recession has changed the tenor of many divorces. Couples not accustomed to concession found themselves in awkward circumstances where the lack of resources forced them to make economical, "couple-focused" decisions even though they are no longer together. Decisions on Property With the housing market depressed, couples are no longer fighting over who ...

By John J. Scura II It was reported in the Washington Post on September 23, 2010, that the already overburdened foreclosure system is now buried in problems due to increased volume, leading to forged signatures, lenders who take shortcuts reviewing borrowers' files, and even judges signing off on foreclosure papers prematurely, deserting their role as final gate keeper. As an attorney, given the fact that we are talking about whether or not people's homes will be saved, I am appalled that such things are happening. Over the last ten years, we have run the gamut from ...

Walt Disney's grandchildren have been entangled in a complex family feud in Maricopa County Probate Court over their inheritance. The controversy was covered in depth by the Arizona Republic, and illustrates the problems that can arise when co-trustees, family and friends fight over an inheritance. The Beginning of the Story Once upon a time, everything seemed wonderful for the Disney family. Walt's youngest daughter, Sharon, married Bill Lund in 1968. Bill was instrumental in helping Disney find the sites for Disneyland and Walt Disney World--the Happiest Places ...

The Hilton Garden Inn Atlanta Airport Hotel (North) offers convenient lodging to guests attending this year's Peach Drop at Underground Atlanta. Part of the largest New Year's Eve celebration in the southeast, visitors can enjoy a day of family fun and entertainment at the Peach Drop. The event begins at 12 noon on Friday, December 31 with various children's activities and entertainment. Festivities also include live music, followed by the decent of the 800 pound Peach from more than 138 feet in the air. The evening will conclude with a spectacular fireworks display at ...

Sentido Hotels & Resorts has announced that from November 2010 to March 2011, the Sentido Tabarka Beach Resort is offering guests who would like to familiarize themselves with the pleasant sensation of thalasso therapy a trial treatment in the hotel's own thalasso therapy center. When booking any application of their choice, guests are welcome to try another one free of charge with the only prerequisite being a minimum stay of four days. In its 2,400 square meter thalasso therapy center, a fully trained staff of twelve - including a physician, therapists and two ...

Hotter Shoes has revealed that men who love their lady dressed to impress will have to go cold turkey this Christmas Day because most women are destined to spoil their cracking Christmas Day outfit by wearing it with comfy slippers, according to a new survey. Peeling sprouts in heels is out for 2010 - with 88% of women refusing to get through December 25 without the comfort of slippers, furry boots or trainers according to the survey commissioned by comfy shoe specialist Hotter Shoes, looking at the festive footwear habits of 2,000 women. Only 12% of women are prepared ...

Nomensa, a leading usability agency, conducted a recent study that assessed the best online UK retailers. Their results, based on various site-specific criteria, revealed New Look to be the highest scoring website, offering the best shopping basket experience. The high street fashion chain, who sell a wide variety of products from must have women's shoes to figure loving black jeans, have invested a lot of time and effort into providing the most efficient checkout service possible in recent times and such awards are certainly testament to what the brand is looking to ...

With the launch of their new live casino platform, gaming software developer Playtech have really managed to blur the line between online and terrestrial casino gaming. Live casinos are a developing online niche combining real dealers and gaming equipment with online playability. The games are conducted in a purpose built dealer studio and video streamed real time to players' computers along with a linked bet interface to allow for remote participation. The playing cards, roulette wheels, roulette balls and the dealers are all real, alleviating the need to rely on ...

1st Class Medical opened the doors to their new showroom in Englewood, Colorado, and it has been busier than ever. 1st Class Medical is an oxygen concentrator division of North Florida Medical a respiratory company in business for over 30 years. Not only do they have brick and mortar pharmacies and service centers but they have become one of the largest online respiratory companies servicing the United States. The new facility has a full showroom with every home and portable oxygen concentrator on the market today. The new showroom is also home for one of the lightest, ...

Today, 3VR Security, Inc., the global leader in Intelligent Video Search and Analytics, announced that it has closed a $17 million round in new financing with a significant increase in valuation, led by Menlo Ventures. The round will fuel 3VR's continued development of its industry-leading intelligent video search and analytics technologies, as well as its expansion into global markets. This funding is the culmination of a record year for the company, in which it also expanded its leadership team with the addition of Aisling MacRunnels as its new chief marketing officer. ...

Most Australians do not approve of IVF or abortion for sex-selection purposes, and most do not think a hypothetical blue or pink pill to select the sex of a child should be legal, a new study has found. The study, led by Dr Rebecca Kippen from the School of Population Health at the University of Melbourne, analysed responses from more than 2,500 people participating in the Australian Survey of Social Attitudes, combined with a series of in-depth parental interviews. The survey found that 69 per cent of respondents disapproved the use of IVF for sex selection, with ...

On May 25th, 2010, the online arm of Upstream, a newspaper for the international oil and gas industry, reported that British Petroleum had started top-kill procedures on the Macondo well in the Gulf of Mexico. "The company said that the operation, which will pump heavy mud down the wellbore in an attempt to gain control of the oil flow and ultimately kill the well, began at 1 pm CST," Upstream reported. The article continued: "Earlier BP Chief Tony Hayward gave the top-kill procedure a 60 percent to 70 percent chance of success." Physicists watching the situation ...

ST. PAUL, Minn. –People living in the "stroke belt" states eat more fried fish than people living in the rest of the country, which may contribute to the high rate of death from stroke in those states, according to a study published in the December 22, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology. Studies have shown that the omega-3 fatty acids in fish, especially fatty fish, may reduce the risk of stroke. Research has shown that frying fish leads to the loss of the natural fatty acids. The study also found that African-Americans ...

STANFORD, Calif. — A study fast-tracked for online publication Dec. 22 in the New England Journal of Medicine has identified an important gene deletion in up to one of every four cases of glioblastoma, the most common adult brain cancer. This deletion contributes to tumor development, promotes resistance to therapy and considerably worsens a patient's survival prospects. The deletion of the gene, known as NFKBIA, triggers biochemical processes similar to those resulting from a better-known aberration common in glioblastomas: alteration of the epidermal growth factor receptor, ...

A new study is unraveling the earliest events associated with neurodegenerative diseases characterized by abnormal accumulation of tau protein. The research, published by Cell Press in the December 22 issue of the journal Neuron, reveals how tau disrupts neuronal communication at synapses and may help to guide development of therapeutic strategies that precede irreversible neuronal degeneration. Tau normally contributes to the supportive framework of proteins in the cell. It is well established that abnormal tau sometimes clumps into neuron-damaging filamentous deposits ...

Washington, DC – Researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, have found that an arsenic-based agent already FDA-approved for a type of leukemia may be helpful in another hard-to-treat cancer, Ewing's Sarcoma (ES). The research, based on animal studies, also suggests the drug might be beneficial in treating medulloblastoma, a highly malignant pediatric brain cancer. In the December 22 issue of the Journal of Clinical Investigation, the investigators describe how years of research has uncovered a common ...

STANFORD, Calif. — Researchers at the Stanford University School of Medicine have discovered that many cancer cells carry the seeds of their own destruction — a protein on the cell surface that signals circulating immune cells to engulf and digest them. On cancer cells, this "eat me" signal is counteracted by a separate "don't eat me" signal that was described in an earlier study. The two discoveries may lead to better cancer therapies, and also solve a mystery about why a previously reported cancer therapy is not more toxic. In the study to be published Dec. 22 in Science ...

Sex in mammals is genetically determined. In humans, females have two X chromosomes, while males have one X and one Y chromosome. However, some individuals are born with male genitalia despite having two X chromosomes, a condition known as XX male sex reversal. A team of researchers, led by Paul Thomas, University of Adelaide, Australia, has now determined that overexpression of the Sox3 gene in mice causes frequent XX male sex reversal. The clinical relevance of this was highlighted by the discovery of genomic rearrangements in the regulatory region of the human SOX3 gene ...

The timing of the onset of puberty is linked to levels of nutrition: later onset is associated with malnutrition, while earlier onset is linked to childhood obesity. A team of researchers, led by Carol Elias, at the University of Texas Southwestern Medical Center, Dallas, has now generated data in mice that run counter to current thinking about the molecular pathway by which nutrition status affects the onset of puberty. Further, the team defines a new regulatory pathway for the process, which, if confirmed in humans, could potentially lead to new approaches to treating ...

Arsenic is usually thought of as a poison. Despite this, it has been used in medicine for over 2000 years, and the arsenic compound arsenic trioxide (ATO) is FDA approved for the treatment of acute promyelocytic leukemia. Now, a team of researchers, led by Aykut Üren, at Georgetown University Medical Center, Washington, has generated data using human cancer cell lines that suggest that ATO might also be of benefit to individuals with certain brain tumors or connective tissue tumors. Certain cancers, in particular brain tumors known as medulloblastomas and connective tissue ...

A multinational research team led by scientists at the National Institutes of Health has found that a genetic variant of a brain receptor molecule may contribute to violently impulsive behavior when people who carry it are under the influence of alcohol. A report of the findings, which include human genetic analyses and gene knockout studies in animals, appears in the Dec. 23 issue of Nature. "Impulsivity, or action without foresight, is a factor in many pathological behaviors including suicide, aggression, and addiction," explains senior author David Goldman, M.D., ...

CAMBRIDGE, Mass.—Researchers at MIT's Picower Institute for Learning and Memory report for the first time how animals' knowledge obtained through past experiences can subconsciously influence their behavior in new situations. The work, which sheds light on how our past experiences inform our future choices, will be reported on Dec. 22 in an advance online publication of Nature. Previous work has shown that when a mouse explores a new space, neurons in its hippocampus, the center of learning and memory, fire sequentially like gunpowder igniting a makeshift fuse. Individual ...

CAMBRIDGE, Mass. (December 22, 2010) – Whitehead Institute researchers have linked hyperactivity in the mechanistic target of rapamycin complex 1 (mTORC1) cellular pathway, to reduced ketone production, which is a well-defined physiological trait of aging in mice. Their results are reported in the December 23 edition of the journal Nature. "This is the first paper that genetically shows that the mTORC1 pathway in mammals affects an aging phenotype," says Whitehead Institute Member David Sabatini. "It provides us with a molecular framework to study an aging-related process ...