(New York, NY) Nearly half the surgeons who made at least $1 million in payments from orthopedic device companies did not have that relationship published in their scientific articles, according to a study released today in the on-line edition of the Archives of Internal Medicine. The study shows that readers are not being adequately informed about conflicts of interest even when the funds involved are significant. The study, conducted by researchers at the New York-based Institute on Medicine as a Profession (IMAP), is the first of its kind to use company records ...

New York (September 13, 2010) - According to a new study a protein crucial for the immune response appears to be a key player in the progression of a devastating form of childhood leukemia called T-cell acute lymphoblastic leukemia (T-ALL). Suppressing the activity of the protein kills the leukemic cells, the study shows, opening a potential avenue to new drugs that could prevent progression of the disease. Led by Iannis Aifantis, PhD, associate professor of pathology and director of the Cancer Stem Cell Program at the NYU Cancer Institute at NYU Langone Medical Center, ...

DALLAS – Sept. 13, 2010 – A tiny molecule that spurs the progression of non-small-cell lung cancer could become a player in fighting the disease, say researchers at UT Southwestern Medical Center, who published a study on how the molecule behaves in mice in the Sept. 14 issue of Cancer Cell. Scientists have known that the molecule microRNA-21, or miR-21, is present in overabundant quantities in human tumors, including non-small-cell lung cancer (NSCLC). Until now, however, it was unclear whether miR-21 contributed to the development of lung cancer, or whether it was simply ...

DAVIS--A research team from the University of California, Davis and Peking University, China, has discovered a novel mechanism as to why the long-term, high-dosage use of the well-known arthritis pain medication, Vioxx, led to heart attacks and strokes. Their groundbreaking research may pave the way for a safer drug for millions of arthritis patients who suffer acute and chronic pain. Using metabolomic profiling to analyze murine (rodent) plasma, the scientists discovered that Vioxx causes a dramatic increase in a regulatory lipid that could be a major contributor to ...

A study led by researchers at the BC Centre for Excellence in HIV/AIDS (BC-CfE) at St. Paul's Hospital and the University of British Columbia has found that supervised injection facilities such as Vancouver's Insite connect clients with addiction treatment, which in turn resulted in greater likelihood of stopping injection drug use for at least six months. The study, recently published in the peer-reviewed journal Drug and Alcohol Dependence, is the first ever to examine the link between a supervised injection facility and injection cessation. "Extensive research has ...

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have discovered key plant enzymes that normally make the energy stored in wood, straw, and other non-edible parts of plants difficult to extract. The findings, published today in Proceedings of the National Academy of Sciences, can be used to improve the viability of sustainable biofuels that do not adversely affect the food chain. The team based at the University of Cambridge, and now part of the BBSRC Sustainable Bioenergy Centre (BSBEC), has identified and studied the genes for ...

An antibiotic appears to be a safe treatment for stroke and a good companion therapy for tPA, the clot buster that is currently the only FDA-approved drug therapy, researchers report. A safety study in 60 stroke patients in Georgia, Kentucky and Oregon found the drug well tolerated even at three-and-one-half times the dose currently used for conditions such as rheumatoid arthritis, according to a research team led by the Medical College of Georgia and the University of Georgia. "It's cheap, safe, well tolerated, easy to administer and can be given with tPA," said Dr. ...

The theory holds that one of the best ways to attract foreign capital consists in the adoption of a reduced level of taxes in certain cases, and above all, in the provision of legal certainty. This aim of attracting foreign investment inspired the measures for the the Entidades Tenedoras de Valores Extranjeros (ETVE) or Spanish holding companies, adopted in Spain in the late 1990's and which led to the establishment of these companies in Spain by multinational companies. However, things are changing, according the head of the UC3M Research Group of Taxation and Finance ...

Mom's advice about cleaning your hands may finally be starting to get through. In the latest observational study sponsored by the American Society for Microbiology and the American Cleaning Institute® (formerly The Soap and Detergent Association), 85% of adults washed their hands in public restrooms, compared with 77% in 2007. The 85% total was actually the highest observed since these studies began in 1996. The results were announced at the Interscience Conference on Antimicrobial Agents and Chemotherapy, an infectious disease meeting sponsored by the American Society ...

Albany, NY—September 13, 2010— New research on the children of LGBTQ people (lesbian, gay, bisexual, transgender and queer) has unequivocally revealed that they are not only psychologically healthy, but often appear to exhibit better social and academic adjustment and a significantly lower incidence of social problems than their peers. A new article published in the journal Family Process critically examines this research, and how it impacts LGBTQ families. According to Family Therapist and Social Work professor, Arlene Istar Lev these excellent outcomes might be masking ...

RUSTON, La – Dr. Bogdan Strimbu, assistant professor of biometrics and quantitative silviculture at Louisiana Tech University's School of Forestry, recently organized and conducted a technical session at the International Union of Forest Research Organization's (IUFRO) XXIII World Congress in Seoul, South Korea. The Congress, held every five years, brings together industry leaders from the IUFRO's eight divisions to help form the future research direction for the global field of forestry. The group also decides the organization's general course of research and associated ...

SAN CLEMENTE, Calif. (September 13, 2010) – USGI Medical, Inc., the Incisionless Surgery company, today announced that updated multi-center results confirm durability of the company's Expandable Tissue Anchors™ up to a year or more in a variety of incisionless gastrointestinal (GI) procedures, including use of a ROSE procedure (Repair of Surgery, Endolumenal) to repair dilated tissue after gastric bypass. These findings, which demonstrate long-term, secure tissue approximation with this scarless "through the mouth" approach in the largest cohort of patients ever reported, ...

Gardeners are used to cross-breeding flowers to produce pretty petals or sweet scents – now scientists have shown the importance of nature's talent for producing new types of flowers. DNA analysis of wild evergreen rhododendrons in the Himalayas has suggested that hundreds of species of the plant could be derived from hybrids – cross-breeds between different species. Their findings may help explain the rich biodiversity of the natural world, as it shows how random pairings of wild plants millions of years ago has led to the development of hundreds of new species that ...

St. Jude Children's Research Hospital investigators have identified a novel structure in cells that serves as a control switch in the body's system for eliminating damaged cells and also offers new therapeutic potential. The findings provide fresh insight into the machinery at work as cells ramp up production of p53 protein following DNA damage. The p53 protein plays a critical role in how cells respond to the stress that damages DNA. The gene that carries instructions for making p53 protein is the most commonly mutated gene in human cancers. Investigators also identified ...

A team of Welsh scientists have successfully cloned a human virus offering new hope for the treatment of potentially life-threatening diseases. Human cytomegalovirus (HCMV) is a major infectious cause of congenital malformations worldwide. The virus is also known to cause life-threatening disease in transplant patients and people with HIV/AIDS. The development of new treatments has been hampered as scientists have been unable to stably replicate HCMV outside the human body. Dr Richard Stanton from Cardiff University's School of Medicine who led the joint research, ...

Beyond the orbit of Neptune reside countless icy rocks known as trans-Neptunian objects (TNOs). One of the biggest, Pluto, is classified as a dwarf planet. The region also supplies us with comets such as famous Comet Halley. Most TNOs are small and receive little sunlight, making them faint and difficult to spot. Now, astronomers using clever techniques to cull the data archives of NASA's Hubble Space Telescope have added 14 new TNOs to the catalog. Their method promises to turn up hundreds more. "Trans-Neptunian objects interest us because they are building blocks ...

GAINESVILLE, Fla. --- Racism may be less of a factor in politics than other realms of life, according to a new University of Florida study, which found few white voters in Florida to be upset by the presidential candidacy of a black man, and many to be proud of it. To assess attitudes among white voters in a southern state about Barack Obama's historic election to the presidency, two UF political scientists analyzed results from four statewide telephone surveys -- each involving between 449 and 829 respondents – conducted in the fall of 2008 and spring of 2009. Their ...

Earthy or musty odors, along with visual evidence of blue-green algae, also known as cyanobacteria, may serve as a warning that harmful cyanotoxins are present in lakes or reservoirs. In a newly published USGS study of cyanobacterial blooms in Midwest lakes, taste-and-odor compounds were found almost every time cyanotoxins were found, indicating odor may serve as a warning that harmful toxins are present. "It is commonly believed that there are no health risks associated with taste-and-odor compounds," said Dr. Jennifer Graham, USGS limnologist and lead scientist on this ...

Though it was once believed that all asteroids are giant pieces of solid rock, later hypotheses have it that some are actually a collection of small gravel-sized rocks, held together by gravity. If one of these "rubble piles" spins fast enough, it's speculated that pieces could separate from it through centrifugal force and form a second collection ― in effect, a second asteroid. Now researchers at Tel Aviv University, in collaboration with an international group of scientists, have proved the existence of these theoretical "separated asteroid" pairs. Ph.D. student ...

EVANSTON, Ill. --- It seems the old nature versus nurture debate can't be won. But a new Northwestern University study of men in the Philippines makes a strong case for nurture's role in male to female differences -- suggesting that rapid weight gain in the first six months of life predicts earlier puberty for boys. Males who experienced rapid growth as babies -- an indication that they were not nutritionally stressed -- also were taller, had more muscle and were stronger, and had higher testosterone levels as young adults. They had sex for the first time at a younger ...

Gainesville, FL. -- The first genetic study to compare nuclear DNA of endangered Antillean manatees in Belize with Florida manatees confirmed their designation as separate subspecies. Belize's manatees, however, were found to have extremely low genetic diversity, raising questions about their long-term genetic viability. The Central American country of Belize hosts the largest known breeding population of Antillean manatees and is touted by biologists for its potential to repopulate other parts of Central America where manatees are severely reduced, rare or absent. ...

When looking for a new physician, patients are often encouraged to select those who are board certified or who have not made payments on malpractice claims. Yet these characteristics are not always a good predictor of which physicians will provide the highest quality medical care, according to a new study from the RAND Corporation, a nonprofit research organization, and the University of Pittsburgh School of Medicine. "We found that the types of information widely available to patients for choosing a physician do not predict whether that physician will deliver evidence-based ...

An unusual wildflower that accumulates metals in its leaves has been found to use them as a kind of 'armor' against bacterial infection. Scientists from Oxford University have shown that when Alpine pennycress (Thlaspi caerulescens) plants accumulate metals in their leaves, they become resistant to attack by the bacterium Pseudomonas syringae pv. maculicola. They report their findings September 9 in the open-access journal PLoS Pathogens. Thlaspi, a small plant in the mustard family that grows on metal-rich soils scattered around Britain and Europe, such as the sites ...

VIDEO: Artificial skin for people and robots could be a reality using the ultra-sensitive sensors developed by Zhenan Bao, associate professor of chemical engineering at Stanford University, and her team. The... Click here for more information. The light, tickling tread of a pesky fly landing on your face may strike most of us as one of the most aggravating of life's small annoyances. But for scientists working to develop pressure sensors for artificial skin for use on ...

RIVERSIDE, Calif. – Molecular machines can be found everywhere in nature, for example, transporting proteins through cells and aiding metabolism. To develop artificial molecular machines, scientists need to understand the rules that govern mechanics at the molecular or nanometer scale (a nanometer is a billionth of a meter). To address this challenge, a research team at the University of California, Riverside studied a class of molecular machines that 'walk' across a flat metal surface. They considered both bipedal machines that walk on two 'legs' and quadrupedal ones ...