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Medicine 2024-09-11

How do human and dog interactions affect the brain?

During social interactions, the activity of the brain’s neurons becomes synchronized between the individuals involved. New research published in Advanced Science reveals that such synchronization occurs between humans and dogs, with mutual gazing causing synchronization in the brain’s frontal region and petting causing synchronization in the parietal region. Both regions are associated with attention. The strength of this synchronization increased with growing familiarity of human–dog pairs over 5 days, and tests indicated that the human is the leader while ...
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Environment 2024-09-11

Can green finance effectively reduce carbon dioxide emissions while promoting economic growth?

New research published in Business Strategy and the Environment based on information from G7 countries demonstrates that green finance—loans, investments, and incentives that support environmentally-friendly projects and activities—can reduce carbon dioxide emissions. Also, data indicate that investments in green projects are profitable. The study found that G7 countries' environmental conditions have been negatively impacted by economic development; however, there are advantages of green finance solutions for economic growth. The study’s investigators ...
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Medicine 2024-09-11

Are there racial differences in the use of opioids after returning home from hospitalizations for hip fractures?

In an analysis of information on 164,170 older adult Medicare beneficiaries who were hospitalized for hip fractures, a similar proportion of Black and white beneficiaries used opioids after they were discharged and returned to the community, but Black beneficiaries consistently received lower doses of the pain medications. In the study published in the Journal of the American Geriatrics Society, investigators observed that on average Black beneficiaries received the equivalent of around 250 fewer milligrams ...
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Science 2024-09-11

Are long stems on flowers an adaptation that encourages bat pollination?

Flowers that are pollinated by bats tend to have long stems that make them stand out from the surrounding foliage. New research published in New Phytologist reveals the evolutionary advantage that this characteristic provides to plants to ensure that they are discovered by bats. In simple backgrounds lacking foliage, bats showed no significant difference in the time it took them to find flowers with long versus short stems, but in complex backgrounds (with arrays of leaves and flowers), bats took nearly twice as much time to locate short-stemmed flowers. Investigators hypothesize that flowers located away from the surrounding foliage likely help bats to distinguish ...
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Medicine 2024-09-11

New research provides insights into how the brain regenerates lost myelin

The neurons of the brain are protected by an insulating layer called myelin. In certain diseases like multiple sclerosis, this protective layer is damaged and lost, leading to death of neurons and disability. New research published in The FEBS Journal reveals the importance of a protein called C1QL1 for promoting the replacement of the specialized cells that produce myelin. The findings could have important implications for the ongoing effort to develop new and improved therapies for the treatment of demyelinating diseases. In experiments conducted in mice, deleting the gene that codes for C1QL1 caused a delay in the rate at which oligodendrocytes ...
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Medicine 2024-09-11

Cells that die during inflammation send wound-healing messages 

Cells that die during inflammation send wound-healing messages  A study by the team of Prof. Kodi Ravichandran (VIB-UGent Center for Inflammation Research) and colleagues found that pyroptosis, a form of programmed cell death traditionally thought to be purely inflammatory, also plays a crucial role in promoting healing and tissue repair. This research, published in Nature, opens new avenues for understanding how our bodies respond to injury and could lead to innovative treatments for wounds and inflammatory diseases.  Dying cells  About a billion cells ...
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Medicine 2024-09-11

Risk of secondary cancers after CAR T therapy may be similar to risk after other cancer treatments

Bottom Line: The frequency of second primary malignancies (SPMs) arising in cancer survivors following treatment with CAR T-cell therapy was statistically comparable to the frequency of SPMs following other standard-of-care therapies, according to a systematic review and meta-analysis. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) Author: Kai Rejeski, MD, a visiting investigator and research fellow in the Adult Bone Marrow Transplant Service at Memorial Sloan Kettering Cancer Center. Background: In January 2024, the U.S. Food and ...
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Enhance and revise for better low-light image enhancement
Science 2024-09-11

Enhance and revise for better low-light image enhancement

With the development of intelligent era, information captured in low-light environments has become increasingly vital. Low-light enhancement technology is now a significant research topic in the domain of machine vision. Designing a robust low-light enhancement algorithm can not only improve the contrast of images, but also restore color and texture details, so as to obtain more distinct and accurate low-light scene information. The team led by Prof. Danhua Cao from Huazhong University of Science and Technology (HUST), ...
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Science 2024-09-11

Multiple ways to evolve tiny knee bone could have helped humans walk upright

The evolution of bones in primates’ knees could have implications for how humans evolved to walk upright, a new study has found. Researchers from King’s College London analysed the presence of the lateral fabella, a bone in the knee the size of a sesame seed, in 93 different species of primates. They found that while most primates have these bones, they are often absent in hominoids, the group of primates that humans belong to alongside chimpanzees, gorillas, gibbons, and others. Yet ...
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UBCO study explores access to psychedelics for therapeutic use
Medicine 2024-09-10

UBCO study explores access to psychedelics for therapeutic use

Feeling safe and comfortable are key when discussing your health and wellbeing with your primary care provider. However, that feeling of comfort and safety can’t be taken for granted among many people who have turned to psychedelic substances—including psilocybin—to help control their symptoms of depression, anxiety or PTSD. Now, a team of UBC Okanagan researchers in the Irving K. Barber Faculty of Arts and Social Sciences has published a study looking into patient perspectives and potential issues when it comes to discussing psychedelics for therapeutic use with their physicians. Dr. Michelle St. Pierre conducts ...
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Medicine 2024-09-10

Lower diligence level linked to higher cardiovascular disease risk in type 2 diabetes

People with type 2 diabetes, who display lower levels of diligence, may have a significantly higher risk of developing cardiovascular disease with which diabetes is strongly associated, finds research published in the open access journal BMJ Open Diabetes Research & Care. While certain personality traits may influence cardiovascular disease risk, adopting a healthy lifestyle is still beneficial, irrespective of diligence level, the findings show. Effective management of type 2 diabetes ...
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Medicine 2024-09-10

Statins cost effective and linked to better health outcomes in older people

Statin treatment is cost effective and linked to better health outcomes in older people with or without previous cardiovascular disease, although the risk reductions were substantially smaller in the latter, reports a modelling on the lifetime benefits of these drugs among the over-70s, published online in the journal Heart. The findings back consideration of these drugs for most over-70s, say the researchers. Statins are used extensively to ward off heart attacks and strokes in middle-aged people, ...
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Science 2024-09-10

Abdominal fat linked to widespread chronic pain, especially in women

Excess abdominal fat is associated with widespread chronic pain, particularly in women, finds the first study of its kind, published in the open access journal Regional Anesthesia & Pain Medicine.   Reducing excess fat deposits in the abdomen may help reduce chronic musculoskeletal pain, especially if it’s experienced at multiple body sites, suggest the researchers. Previously published research has shown that obesity is associated with musculoskeletal pain, but it’s not known if excess fat tissue is linked to chronic musculoskeletal pain and at multiple body sites, ...
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Wearable brain imaging device shines a light on how babies respond in real-world situations
Medicine 2024-09-10

Wearable brain imaging device shines a light on how babies respond in real-world situations

A new technology which uses harmless light waves to measure activity in babies’ brains has provided the most complete picture to date of brain functions like hearing, vision and cognitive processing outside a conventional, restrictive brain scanner, in a new study led by researchers at UCL and Birkbeck. The wearable brain imaging headgear, which was developed in collaboration with UCL spin-out Gowerlabs, found unexpected activity in the prefrontal cortex, an area of the brain that processes emotions, in response to social stimuli, appearing to confirm ...
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Science 2024-09-10

"Cuddle hormone" oxytocin may provide pain relief and help curb harmful opioid use

In the midst of America’s growing opioid crisis, a much healthier alternative to long-term pain management is emerging — one affectionately known as “the cuddle hormone,” or oxytocin. University of Florida researchers are currently investigating whether a synthetic version of this naturally-occurring human hormone can be used in conjunction with prescription drugs to help curb opioid addictions, especially in susceptible older adults. An interdisciplinary research team is conducting the two-year study, with $414,375 in funding from the National ...
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Science 2024-09-10

Study reveals mechanism that activates glucose production in the liver in response to stress

A study led by Brazilian researchers has produced a detailed description of the morphology of the nerves in the liver and how they control production of glucose when the organism is under stress. This process is known as hepatic gluconeogenesis. It is a key metabolic function of the liver that helps maintain a normal blood sugar level, especially when fasting and at times of high energy needs.  An article on the study, which entailed experiments with mice, is published in the journal Metabolism. According to the authors, the sympathetic nerves that stimulate the release of noradrenaline in the liver helped ...
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Aumolertinib maintenance after chemoradiotherapy in stage III non-small cell lung cancer improves PFS compared to placebo
Medicine 2024-09-10

Aumolertinib maintenance after chemoradiotherapy in stage III non-small cell lung cancer improves PFS compared to placebo

(San Diego, Calif.--September 9, 2024, 10:05 a.m.) -- The epidermal growth factor receptor tyrosine kinase inhibitor aumolertinib demonstrated improved progression-free survival compared to placebo without any significant new adverse reactions, according to data from the POLESTAR study presented today at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer. Consolidation therapy with durvalumab is established as the standard of care for patients who do not experience disease progression following concurrent chemoradiotherapy. However, it is unknown what the specific benefit ...
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Science 2024-09-10

Weight loss of up to 13% achieved in three months with once-a-day tablet, phase 1 trial finds

Individuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) will hear. Amycretin, which is being developed by the Danish pharmaceutical company Novo Nordisk A/S, mimics the action of two peptide hormones in one single molecule. Amycretin is both an amylin and glucagon-like peptide-1 (GLP-1) receptor agonist. Both of these play a key role in appetite regulation ...
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Medicine 2024-09-10

Time-restricted eating improves blood sugar control in adults at risk of type 2 diabetes regardless of time of day

Restricting the eating window to 8 hours a day significantly improves blood glucose control in adults at risk of type 2 diabetes irrespective of whether it is earlier or later in the day, according to a randomised crossover trial to be presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept). “Our study found that restricting eating to a window of 8 hours per day significantly improved the daily time spent in the normal blood glucose range and reduced fluctuations in blood glucose levels. However, altering the 8-hour restricted eating period ...
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Medicine 2024-09-10

Individuals with complications of diabetes are at higher risk of gum disease, Danish study finds

Gum disease is more common in individuals with microvascular complications of diabetes, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) and published in The Journal of Dental Research has found. Periodontitis is a chronic inflammatory disease that affects the gums and the bones supporting the teeth. It is caused by the accumulation of bacterial plaque, and if left untreated, it can lead to the destruction of the tissues that hold the teeth in place, ultimately resulting in tooth loss. “This tooth loss can affect essential functions like chewing and speaking, while ...
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Medicine 2024-09-10

Weight loss drug liraglutide is safe and effective in children under 12, study finds

The obesity medication liraglutide is safe and effective in children aged 6 to <12 years, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September), and published simultaneously in the New England Journal of Medicine (NEJM), has found. Childen aged six to <12 years who took liraglutide for just over a year experienced a reduction in BMI of 7.4% compared to placebo and experienced improvements in blood pressure and blood sugar control. The results of ...
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Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal
Medicine 2024-09-10

Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal

Results from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received chemotherapy before surgery to remove advanced squamous cell-type cancer of the nose or sinus. The European Society of Medical Oncology is highlighting the trial at its ESMO Congress 2024 in Barcelona, Spain. Surgery is required for these patients but at a high physical cost. Patients enrolled in this trial had signs that surgery would result in loss of the eye, the base of the skull bone, or both. However, in the randomized prospective trial EA3163, patients receiving chemotherapy ...
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Science 2024-09-10

The glug of it all

As Rohit Velankar, now a senior at Fox Chapel Area High School, poured juice into a glass, he could feel that the rhythmic glug, glug, glug was flexing the walls of the carton. Rohit pondered the sound, and wondered if a container’s elasticity influenced the way its fluid drained. He initially sought the answer to his question for his science fair project, but it spiraled into something more when he teamed up with his father, Sachin Velankar, a professor of chemical and petroleum engineering at the University of Pittsburgh Swanson School of Engineering.  They set up an experiment ...
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UTA to build netted drone facility in Fort Worth
Engineering 2024-09-10

UTA to build netted drone facility in Fort Worth

The University of Texas at Arlington is expanding its research and innovation capabilities by building a $2.3 million, state-of-the-art outdoor netted drone facility. The Maverick Autonomous Vehicle Research Center (MAVRC) will be located at the UT Arlington Research Institute (UTARI) in Fort Worth, with a planned completion date of January 2025. “MAVRC will significantly and positively impact UTA’s presence in the region by supporting the university-industry-government-community ecosystem focused ...
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Energy 2024-09-10

Streamlining energy regulations on Native American reservations could help alleviate poverty

MADISON–Land was once set aside as Native American reservations because it was undesirable and low in resources, but now interested Native Americans may have economic leverage in the growing industry of clean energy. A team of researchers led by UW–Madison professors Dominic Parker and Sarah Johnston quantified the economic potential of wind and solar energy projects on these lands and discussed the regulatory barriers for tribes wishing to tap into it. “This is the first comprehensive ...
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