Eggs reveal what may happen to brain on impact
Put to the test, impact from rotational deceleration causes tremendous egg yolk deformation
2021-01-19
(Press-News.org) WASHINGTON, January 19, 2021 -- What causes brain concussions? Is it direct translational or rotational impact? This is one of the research areas currently being explored by Qianhong Wu's lab at Villanova University.
Our brains consist of soft matter bathed in watery cerebrospinal fluid (CSF) inside a hard skull. An impact on the hard skull is transmitted through the thin layer of CSF within the subarachnoid space to the soft brain matter.
In Physics of Fluids, from AIP Publishing, Wu and co-authors Ji Lang and Rungun Nathan describe studying another system with the same features, an egg, to search for answers. An egg resembles the brain, because its soft yolk is bathed within a liquid egg white inside a hard shell.
Considering that in most concussive brain injuries, the skull does not break, Wu wanted to find out if it was possible to break or deform the egg yolk without breaking the eggshell.
The researchers did a simple experiment using an egg scrambler, from which they could see that rotational force can easily break the egg yolk and make it mix with the egg white.
In terms of basic concepts behind this work, a soft capsule -- membranebound soft matter -- is bathed within a contained liquid. The capsule has an impermeable membrane, separating the liquid inside the capsule from the outside.
Two types of impacts can be imposed on the outer container. A translational impact is one that hits the container directly, while a rotational impact occurs when the outer container is accelerated or decelerated rotating. The latter arises naturally in sports when helmets are not round. Consider, for instance, the pair of stiffening ridges behind many ice hockey helmet designs.
The researchers discovered something quite counterintuitive and very surprising. Direct translational impact does not cause the egg deformation, while rotational deceleration causes tremendous egg yolk deformation. This finding sheds light on the motion and deformation of our brain when the head is exposed to sudden external impacts.
"We suspect that rotational, especially decelerational rotational, impact is more harmful to brain matter," said Wu. "The large deformation of brain matter during this process induces the stretch of neurons and causes the damage."
This finding explains why boxers will very likely faint if hit on the chin.
"Considering the chin is the farthest point from the neck, hitting on the chin could cause the highest rotational acceleration/deceleration of the head," he said.
When it comes to concussions, which are a serious issue for public health, "it remains unclear how the brain is injured and how to avoid such injuries," said Wu.
"Critical thinking, along with simple experiments within the kitchen, led to a series of systematic studies to examine the mechanisms that cause egg yolk deformation," Wu said. "We hope to apply the lessons learned from it to the study of brain biomechanics as well as other physical processes that involve soft capsules in a liquid environment, such as red blood cells."
As the first study of its kind, this work provides a new perspective for understanding the response of a membranebound soft object to sudden external impacts. This new perspective will interest those designing helmets.
INFORMATION:
The article "How to deform an egg yolk? On the study of soft matter deformation in a liquid environment" is authored by Qianhong Wu, Ji Lang, and Rungun Nathan. It will appear in Physics of Fluids on Jan. 19, 2021 (DOI: 10.1063/5.0035314). After that date, it can be accessed at https://aip.scitation.org/doi/10.1063/5.0035314.
ABOUT THE JOURNAL
Physics of Fluids is devoted to the publication of original theoretical, computational, and experimental contributions to the dynamics of gases, liquids, and complex fluids. See https://aip.scitation.org/journal/phf.
ELSE PRESS RELEASES FROM THIS DATE:
2021-01-19
For the first time ever, a team of scientists, led by the University of Bristol, have described in detail a dinosaur's cloacal or vent - the all-purpose opening used for defecation, urination and breeding.
Although most mammals may have different openings for these functions, most vertebrate animals possess a cloaca.
Although we know now much about dinosaurs and their appearance as feathered, scaly and horned creatures and even which colours they sported, we have not known anything about how the vent appears.
Dr Jakob Vinther from the University of Bristol's School of Earth Sciences, along with colleagues Robert Nicholls, a palaeoartist, and Dr Diane Kelly, ...
2021-01-19
With a small snout, a short and curled tail, and a big, round stomach, mini pigs are the epitome of cute--and sometimes, they snore. Now, researchers think these snoring pigs can be used to study obstructive sleep apnea. A study appearing January 19 in the journal Heliyon found that obese Yucatan mini pigs do have naturally occurring sleep apnea and that MRI scans taken while they're in sedated sleep can be used to gain new insights into what happens in the airways during sleep apnea episodes via computational flow dynamic (CFD) analysis.
"These are very fat pigs," says first author Zi-Jun Liu, a research professor and principal investigator in the Department of Orthodontics ...
2021-01-19
WASHINGTON, January 19, 2021 -- Biomedical engineers developed a technique to observe wound healing in real time, discovering a central role for cells known as fibroblasts. The work, reported in APL Bioengineering, by AIP Publishing, is the first demonstration of a wound closure model within human vascularized tissue in a petri dish.
Prior investigations of wound healing have used animal models, but healing in humans does not occur the same way. One difference is that wounds in mice and rats, for example, can heal without granulation tissue, a type of tissue critical to the healing of human wounds.
Granulation tissue forms after blood coagulates, and the wound scabs over. Coagulation creates a fibrin network that serves as a temporary matrix. Granulation tissue then takes over, ...
2021-01-19
WASHINGTON, January 19, 2021 -- The quest for ever-smaller electronic components led an international group of researchers to explore using molecular building blocks to create them. DNA is able to self-assemble into arbitrary structures, but the challenge with using these structures for nanoelectronic circuits is the DNA strands must be converted into highly conductive wires.
Inspired by previous works using the DNA molecule as a template for superconducting nanowires, the group took advantage of a recent bioengineering advance known as DNA origami to fold DNA into arbitrary shapes.
In AIP ...
2021-01-19
Youths with mood disorders who use and abuse cannabis (marijuana) have a higher risk for self-harm, death by all causes and death by unintentional overdose and homicide, according to research led by The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine.
Study findings are published in the JAMA Pediatrics.
"Marijuana use and addiction is common among youth and young adults with mood disorders, but the association of this behavior with self-harm, suicide and overall mortality risk is poorly understood in this already vulnerable population. These findings ...
2021-01-19
If you ever saw a honeybee hopping elegantly from flower to flower or avoiding you as you passed by, you may have wondered how such a tiny insect has such perfect navigation skills. These flying insects' skills are partially explained by the concept of optical flow: they perceive the speed with which objects move through their field of view. Robotics researchers have tried to mimic these strategies on flying robots, but with limited success. A team of TU Delft and the Westphalian University of Applied Sciences researchers therefore present an optical flow-based learning process that allows robots to estimate distances through the visual appearance (shape, color, texture) of the objects ...
2021-01-19
The older we grow, the weaker our muscles get, riddling old age with frailty and physical disability. But this doesn't only affect the individual, it also creates a significant burden on public healthcare. And yet, research efforts into the biological processes and biomarkers that define muscle aging have not yet defined the underlying causes.
Now, a team of scientists from lab of Johan Auwerx at EPFL's School of Life Sciences looked at the issue through a different angle: the similarities between muscle aging and degenerative muscle diseases. They have discovered protein aggregates that deposit in skeletal muscles during natural aging, and that blocking this can prevent the detrimental features of muscle ...
2021-01-19
FLAGSTAFF, Ariz. -- Jan. 19, 2021 -- The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.
COVID-19 isn't humanity's first encounter with a coronavirus, so named because of the corona, or crown-like, protein spikes on their surface. Before SARS-CoV-2 -- the virus that causes COVID-19 -- humans have navigated at least 6 other types of coronaviruses.
The study sought to understand how coronaviruses (CoVs) ignite the human immune system and conduct a deeper dive on the inner workings of the antibody response. The ...
2021-01-19
Researchers looked at neurons within the basal ganglia, a part of the brain that, when damaged, can severely impact a person's motor ability, making seemingly simple reaching-and-grasping tasks near impossible
They focused on a large group of neurons, which has two distinct types - D1 direct striatal output neurons and D2 indirect output neurons
These neurons are implicated in the development of Parkinson's and Huntington's - neurodegenerative diseases that result in the progressive degeneration or death of nerve cells
In this research, mice were trained to reach for and grasp a chocolate pellet, and optical methods were used to either excite or inhibit their D1 or D2 neurons
The researchers ...
2021-01-19
Biology - Volcanic microbes
Oak Ridge National Laboratory contributed to an international study that found almost 300 novel types of microbes living near a deep sea volcano. These microbes, which could be used in biotechnology, reveal new insights about their extreme underwater environment.
Two distinct communities of heat-loving and many acid-loving microbes live near Brother's Volcano, located about 200 miles northeast of New Zealand and 6,000 feet underwater. Known as extremophiles, these microbes thrive in water heated by magma and hydrothermal vents.
Though they live close to one another, the microbial communities reflect differences in water chemistry and temperature from geological ...
LAST 30 PRESS RELEASES:
[Press-News.org] Eggs reveal what may happen to brain on impact
Put to the test, impact from rotational deceleration causes tremendous egg yolk deformation