Metformin plus insulin for preexisting diabetes or gestational diabetes in early pregnancy

JAMA

2023-12-12

(Press-News.org) About The Study: Using metformin plus insulin to treat preexisting type 2 or gestational diabetes diagnosed early in pregnancy did not reduce a composite neonatal adverse outcome in a randomized clinical trial of 794 pregnant adults. The effect of reduction in odds of a large-for-gestational-age infant observed after adding metformin to insulin warrants further investigation.

Authors: Kim A. Boggess, M.D., of the University of North Carolina at Chapel Hill, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2023.22949)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Metformin plus insulin for preexisting diabetes or gestational diabetes in early pregnancy

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