Prenatal exposure to chemical mixtures and metabolic syndrome risk in children

JAMA Network Open

2024-05-23

(Press-News.org) About The Study: The findings of this cohort study suggest that prenatal exposure to endocrine-disrupting chemical mixtures may be associated with adverse metabolic health in children. Given the pervasive nature of endocrine-disrupting chemicals and the increase in metabolic syndrome, these findings hold substantial public health implications.

Corresponding Author: To contact the corresponding author, Martine Vrijheid, Ph.D., email martine.vrijheid@isglobal.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2024.12040)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12040?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052324

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Effectiveness of a school- and primary care–based HPV vaccination intervention

2024-05-23

About The Study: In this cluster randomized trial, within the context of the late COVID-19 pandemic period and limited school and general practitioner participation, at-school human papillomavirus (HPV) vaccination significantly increased vaccination coverage. The trial did not show a significant effect for training general practitioners and education and motivation, although it may be observed after more time has elapsed after the intervention. Corresponding Author: To contact the corresponding author, Morgane Michel, Ph.D., email morgane.michel@aphp.fr. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.11938) Editor’s ...

Exposure to mixtures of endocrine-disrupting chemicals during pregnancy is associated with higher odds of metabolic syndrome in children

2024-05-23

The term ‘metabolic syndrome’ (MetS) encompasses a group of factors, such as abdominal obesity, hypertension and insulin resistance, that together increase the risk of cardiovascular disease and type 2 diabetes. A new study suggests that prenatal exposure to a combination of endocrine disrupting chemicals (EDCs) is associated with a poorer metabolic health in childhood, which in turn may contribute to an increased risk of metabolic syndrome in adulthood. The research, led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, has been published in JAMA Network Open. EDCs ...

Sea of love: Behind the unusual sexual parasitism of deep-water anglerfishes

2024-05-23

New Haven, Conn. – As the planet’s most expansive ecosystem, the deep sea can be a tough place to find a mate. Though, scientists say, some deep-sea anglerfishes evolved a unique method of reproduction that ensures that once they land a partner in the vast open waters, they remain latched for life. These anglerfishes, called ceratioids, reproduce through sexual parasitism, in which the tiny males attach to their much larger female counterparts to mate. In some species, the males bite the females ...

USTC proposes therapeutic approach for inflammatory bowel disease

2024-05-23

In a study published in Cell Host & Microbe, a research team led by Prof. PAN Wen from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, in collaboration with research teams led by Prof. ZHU Shu and Prof. SONG Xinyang, demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis. On the basis of this mechanism, they proposed a possible approach to restore ISC function in colitis. Inflammatory bowel disease (IBD) is a chronic disease characterized by the microbial ...

International planet hunters unveil massive catalog of strange worlds

2024-05-23

While thousands of planets have been discovered around other stars, relatively little is known about them. A NASA catalog featuring 126 exotic, newly discovered worlds includes detailed measurements that allow for comparisons with our own solar system. The catalog details a fascinating mix of planet types beyond our solar system, from rare worlds with extreme environments to ones that could possibly support life. The planets were analyzed by a large, international team of scientists using NASA’s Transiting Exoplanet Survey Satellite (TESS) in collaboration with the W.M. Keck Observatory on Maunakea, Hawai’i. They are described in today’s edition of The Astrophysical ...

Innovative techniques open new avenues in drug discovery for brain diseases

2024-05-23

Oak Brook, IL – Volume 29, Issue 2 of SLAS Discovery features two review articles, six original research articles covering phenotypic screening perspectives, medulloblastoma therapies and interventions for neurodegenerative diseases. Reviews Perspectives on phenotypic screening−Screen Design and Assay Technology Special Interest Group The SLAS Screen Design and Assay Special Interest Group articulate the group’s discussion held at the SLAS2023 International Conference. Collectively, the group members’ perspectives highlight various challenges, progress and proposed solutions to ...

SLAS Technology presents: Advances in Synthetic Biology

2024-05-23

Oak Brook, IL – Volume 29, Issue 2 of SLAS Technology, includes three original research articles covering skin cutaneous melanoma, glycan-bead coupling and acoustic ejection mass spectrometry, and eight articles from the Advances in Synthetic Biology Special Issue. Original Research Validating core therapeutic targets for osteoporosis treatment based on integrating network pharmacology and informatics This study recognizes metabolism-related lncRNAs associated with osteoporosis (OP) and constructed a prediction model for OP progression using these lncRNAs. The authors identify central therapeutic targets including CBFB, GLO1, NFKB2 ...

YouTubers cheer people up more than casual friends

2024-05-23

One-sided relationships with YouTubers are more emotionally fulfilling than talking to casual friends, a new study suggests. The University of Essex research discovered people feel watching online stars like Zoella, KSI and PewDiePie can cheer them up more than weak-tie acquaintances – like neighbours or co-workers. Dr Veronica Lamarche, from the Department of Psychology, also found people feel liked, respected and understood by fictional characters. The study suggests watching online celebrities offer positive reinforcement - despite them not being able to respond. Dr ...

Researchers advocate for structured framework to study the benefits of exercise training in multiple sclerosis rehabilitation

2024-05-23

East Hanover, NJ – May 22, 2024 – A team of experts in multiple sclerosis (MS) research recommends a structured approach to the study of mechanisms of exercise training for improving outcomes for multiple sclerosis (MS). In a review article, “Focusing on neural mechanisms of exercise training benefits in multiple sclerosis,” (doi: 10.1016/j.msard.2024.105633) published in Multiple Sclerosis and Related Disorders on April 16, 2024, they emphasize the value of adopting an experimental medicine framework to optimize ...

Researchers detect hidden threats with advanced x-ray imaging

2024-05-23

WASHINGTON — Researchers have combined various x-ray imaging technologies to create multi-contrast images that can be used to detect threatening materials such as explosives in thousands of complicated scenarios. The new approach, which also leverages readily available machine learning procedures for materials classification, could be useful for security screening as well as applications in the life and physical sciences. “This method is particularly well suited to discriminating objects with very ...

Prenatal exposure to chemical mixtures and metabolic syndrome risk in children

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: