PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Quantitative Biology journal features groundbreaking perspectives on large cellular models

Quantitative Biology journal features groundbreaking perspectives on large cellular models
2024-07-23
(Press-News.org)

In a landmark move to advance the frontiers of artificial intelligence, the Quantitative Biology (QB) journal has published a comprehensive commentary titled "Current Opinions on Large Cellular Models," highlighting the cutting-edge developments in the field of large cellular models (LCMs). The journal has brought together a consortium of leading scholars from China, the United States, and Canada to delve into the future of AI-driven biological research.

The commentary features influential authors behind some of the most impactful LCMs, such as scBERT, Geneformer, scGPT, scFoundation, and GeneCompass. These AI models have revolutionized the way single-cell data is processed and analyzed, offering unprecedented insights into biological processes and scientific discoveries.

"The integration of AI, particularly large-scale pre-training technologies, is charting a new course for the future of quantitative biology research," said Xuegong Zhang, a prominent voice in the field and a contributing author of the commentary.

The commentary offers a detailed overview of the general framework (Figure 1) and core AI concepts behind these models, as well as a forward-looking discussion on how these models can be effectively integrated with biological knowledge. It also addresses the critical challenges faced during the research and development of LCMs, including the scaling law issues and the need for data pre-training.

END


[Attachments] See images for this press release:
Quantitative Biology journal features groundbreaking perspectives on large cellular models

ELSE PRESS RELEASES FROM THIS DATE:

Time-division multiplexing planning and design strategies for parking lots in compact cities

Time-division multiplexing planning and design strategies for parking lots in compact cities
2024-07-23
Compact city is an urban planning strategy aimed at promoting environmental, economic, and social sustainability through spatial configurations featured with relatively high density and mixed land use. The continuous growth in car ownership forces cities to construct more static transportation facilities such as parking lots, squeezing the activity spaces of residents and consequently giving rise to a series of efficiency and equity issues. Thus, the conflict between people and vehicles in compact cities is increasingly prominent and urgently ...

New imaging technique reveals intracellular energy dynamics in kidney cells

New imaging technique reveals intracellular energy dynamics in kidney cells
2024-07-23
The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge. The kidneys are among the most energy-intensive organs in the body. For the kidneys to function, they constantly produce and consume large amounts of adenosine triphosphate (ATP), which is a chemical that the body uses to store and transport energy. However, ATP dynamics—the changes over time in ATP production and utilization—within the kidney have been poorly understood because of the lack of suitable imaging technologies.   Using a newly developed ATP imaging system, the researchers ...

Could smart guide RNAs usher in an era of personalized medicine?

Could smart guide RNAs usher in an era of personalized medicine?
2024-07-23
Guides typically assist tourists with directions, but the experience could be greatly enhanced if they offered personalized services tailored to individual interests. Recently, researchers have transformed guide RNAs, which direct enzymes, into a smart RNA capable of controlling networks in response to various signals. This innovative research is gaining significant attention in the academic community.   A research team consisting of Professor Jongmin Kim and PhD candidates Hansol Kang and Dongwon Park from the Department of Life Sciences at POSTECH has developed a multi-signal ...

Recent progress on VOC pollution control via the catalytic method

Recent progress on VOC pollution control via the catalytic method
2024-07-23
Volatile organic compounds (VOCs), with toxicity and irritability, could cause atmospheric environmental problems such as haze and photochemical smog, seriously threatening the ecological environment and human health. The primary source of VOCs is human production, such as the petrochemical industry, pharmaceutical industry, footwear industry, electronic manufacturing, and cooking fumes. Catalytic oxidation technology can highly effectively remove organic pollutants without secondary pollution, and it is receiving increasing attention in VOC pollution control. In real-world operating conditions, the ...

Stabilizing perovskite solar cells in hot and humid conditions

Stabilizing perovskite solar cells in hot and humid conditions
2024-07-23
HONG KONG (21 July 2024) --- The progress of solar energy technology took a step forward recently with the development of a groundbreaking living passivator at City University of Hong Kong (CityUHK) that can substantially enhance the stability and efficiency of perovskite solar cells. This newly developed passivator is a type of corrosion inhibitor that appreciably changes the potential of a metal. The CityUHK technology leverages dynamic covalent bonds that activate on exposure to moisture and heat, enabling it to evolve new passivators in response to environmental factors. This innovative approach allows for real-time repair and maintenance of perovskite solar cells. ...

Trajectory of type 1 diabetes risk shifts after age 10 years between at-risk males and females

2024-07-23
New research presented at this year’s Annual Meeting of the European Association for Study of Diabetes (Madrid, Spain, 9-13 September) shows that the risk of developing type 1 diabetes (T1D) decreases markedly in girls after age 10 years, while the risk in boys stays the same. Furthermore, risk of T1D is significantly higher boys with a single autoantibody than their female counterparts, suggesting the sex could be linked with autoantibody development, indicating the importance of incorporating sex in the assessment ...

Long-term sulfonylurea use linked to higher risk of low blood sugar unawareness in type 2 diabetes patients

Long-term sulfonylurea use linked to higher risk of low blood sugar unawareness in type 2 diabetes patients
2024-07-22
Background and Goal: Sulfonylureas are a class of oral medications used to manage blood glucose levels in patients with type 2 diabetes. These drugs increase insulin production regardless of blood sugar levels. For this reason, the drugs can cause blood sugar to drop too low, leading to hypoglycemia. The goal of this study was to compare how prevalent impaired awareness of hypoglycemia was when patients with type 2 diabetes were treated with either insulin or sulfonylureas for both long and short-term periods. Study Approach: Researchers collected data from a group of 898 participants with type 2 diabetes enrolled in pharmacies, clinics, ...

Health care providers weigh in on their experiences developing an AI tool to understand primary care patients’ social determinants of health

Health care providers weigh in on their experiences developing an AI tool to understand primary care patients’ social determinants of health
2024-07-22
Background and Goal: Social determinants of health are the conditions in which people are born, grow, live, work, and age. These conditions include income, education, and access to health care. Knowledge of these factors is essential for primary care clinicians to deliver fair and complete care, plan programs and distribute resources effectively. However, this information is rarely captured consistently in clinical settings. This study identified how an Artificial Intelligence (AI) social determinants of health tool can be designed using a collaborative design strategy with input from primary care team members. Study Approach:  ...

Pandemic’s impact on primary care: Significant drop in visits and uneven telehealth use across patient groups

Pandemic’s impact on primary care: Significant drop in visits and uneven telehealth use across patient groups
2024-07-22
Background and Goal: The COVID-19 pandemic likely worsened disparities in access to primary care. The goal of this study was to quantify the nationwide decline in primary care visits and the increase in telehealth utilization and explore whether certain groups of patients were disproportionately impacted. Study Approach: Researchers used primary care electronic health record data from the American Family Cohort— to examine  the percentage change in total visit volume, change in in-person visit volume, and telehealth ...

Transforming clinical practice initiative linked to reduced emergency department visits

2024-07-22
Background and Goal: The Transforming Clinical Practice Initiative was a four-year nationwide program aimed at improving outpatient health care quality. The initiative, funded by the Centers for Medicare & Medicaid Services, also prepared practices for payment systems based on care quality rather than service quantity and included a Change Package to guide practice transformations. This research brief examines whether these transformations were associated with reductions in emergency department visits among both primary and specialty care practices. Study Approach: Researchers analyzed data from 3,773 practices in the Transforming Clinical Practice ...

LAST 30 PRESS RELEASES:

To reach net-zero, reverse current policy and protect largest trees in Amazon, urge scientists

Double trouble: Tobacco use and Long COVID

Eating a plant-forward diet is good for your kidneys

Elucidating liquid-liquid phase separation under non-equilibrium conditions

Fecal microbiome and bile acid profiles differ in preterm infants with parenteral nutrition-associated cholestasis

The Institute of Science and Technology Austria (ISTA) receives €5 million donation for AI research

Study finds link between colorblindness and death from bladder cancer

Tailored treatment approach shows promise for reducing suicide and self-harm risk in teens and young adults

Call for papers: AI in biochar research for sustainable land ecosystems

Methane eating microbes turn a powerful greenhouse gas into green plastics, feed, and fuel

Hidden nitrogen in China’s rice paddies could cut fertilizer use

Texas A&M researchers expose hidden risks of firefighter gear in an effort to improve safety and performance

Wood burning in homes drives dangerous air pollution in winter

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: January 23, 2026

ISSCR statement in response to new NIH policy on research using human fetal tissue (Notice NOT-OD-26-028)

Biologists and engineers follow goopy clues to plant-wilting bacteria

What do rats remember? IU research pushes the boundaries on what animal models can tell us about human memory

Frontiers Science House: did you miss it? Fresh stories from Davos – end of week wrap

Watching forests grow from space

New grounded theory reveals why hybrid delivery systems work the way they do

CDI scientist joins NIH group to improve post-stem cell transplant patient evaluation

Uncovering cancer's hidden oncRNA signatures: From discovery to liquid biopsy

Multiple maternal chronic conditions and risk of severe neonatal morbidity and mortality

Interactive virtual assistant for health promotion among older adults with type 2 diabetes

Ion accumulation in liquid–liquid phase separation regulates biomolecule localization

Hemispheric asymmetry in the genetic overlap between schizophrenia and white matter microstructure

Research Article | Evaluation of ten satellite-based and reanalysis precipitation datasets on a daily basis for Czechia (2001–2021)

Nano-immunotherapy synergizing ferroptosis and STING activation in metastatic bladder cancer

Insilico Medicine receives IND approval from FDA for ISM8969, an AI-empowered potential best-in-class NLRP3 inhibitor

Combined aerobic-resistance exercise: Dual efficacy and efficiency for hepatic steatosis

[Press-News.org] Quantitative Biology journal features groundbreaking perspectives on large cellular models